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U.S. Biotech Industry Analysis
UpdatedNov 20, 2025
DataAggregated Company Financials
Companies545
- 7D1.0%
- 3M16.3%
- 1Y16.0%
- YTD20.6%
The Biotech is pretty flat in the last 7 days, but Exact Sciences has stood out, gaining 49%. As for the the longer term, the industry is up 16% over the past 12 months. Looking forward, earnings are forecast to grow by 24% annually.
Industry Valuation and Performance
Has the U.S. Biotech Industry valuation changed over the past few years?
| Date | Market Cap | Revenue | Earnings | PE | Absolute PE | PS |
|---|---|---|---|---|---|---|
| Fri, 21 Nov 2025 | US$1.2t | US$163.8b | -US$16,250,245,666.11 | 17.4x | -74x | 7.3x |
| Sun, 19 Oct 2025 | US$1.2t | US$163.4b | -US$18,206,489,780.58 | 16.4x | -64.1x | 7.1x |
| Tue, 16 Sep 2025 | US$1.1t | US$163.6b | -US$18,378,517,336.68 | 15.8x | -58.3x | 6.6x |
| Thu, 14 Aug 2025 | US$1.0t | US$163.2b | -US$14,658,010,083.94 | 15.6x | -70.7x | 6.4x |
| Sat, 12 Jul 2025 | US$985.4b | US$155.8b | -US$23,408,172,286.86 | 18.5x | -42.1x | 6.3x |
| Mon, 09 Jun 2025 | US$951.3b | US$155.9b | -US$23,930,730,032.61 | 16.8x | -39.8x | 6.1x |
| Wed, 07 May 2025 | US$949.3b | US$154.1b | -US$25,408,936,426.34 | 18.3x | -37.4x | 6.2x |
| Fri, 04 Apr 2025 | US$791.2b | US$118.6b | -US$37,117,653,368.22 | 21.5x | -21.3x | 6.7x |
| Sun, 02 Mar 2025 | US$850.7b | US$118.9b | -US$37,265,127,499.97 | 17x | -22.8x | 7.2x |
| Tue, 28 Jan 2025 | US$983.3b | US$149.5b | -US$26,320,225,889.85 | 17.1x | -37.4x | 6.6x |
| Thu, 26 Dec 2024 | US$990.4b | US$149.9b | -US$26,369,148,329.00 | 16x | -37.6x | 6.6x |
| Sat, 23 Nov 2024 | US$1.0t | US$150.0b | -US$26,559,949,256.44 | 17x | -37.7x | 6.7x |
| Mon, 21 Oct 2024 | US$908.0b | US$113.1b | -US$35,950,283,773.02 | 21.7x | -25.3x | 8x |
| Wed, 18 Sep 2024 | US$929.9b | US$113.2b | -US$35,966,527,614.94 | 22.9x | -25.9x | 8.2x |
| Fri, 16 Aug 2024 | US$870.9b | US$113.2b | -US$36,254,285,538.64 | 22.2x | -24x | 7.7x |
| Sun, 14 Jul 2024 | US$1.2t | US$164.5b | -US$28,119,714,352.84 | 29.4x | -42.5x | 7.3x |
| Tue, 11 Jun 2024 | US$1.2t | US$164.5b | -US$26,797,092,425.07 | 28.1x | -43.3x | 7.1x |
| Thu, 09 May 2024 | US$1.1t | US$164.6b | -US$26,520,766,232.38 | 24.3x | -42.5x | 6.8x |
| Sat, 06 Apr 2024 | US$1.1t | US$164.4b | -US$23,433,178,577.03 | 25x | -47.8x | 6.8x |
| Mon, 04 Mar 2024 | US$1.2t | US$167.9b | -US$21,330,880,627.75 | 15.9x | -56.4x | 7.2x |
| Wed, 31 Jan 2024 | US$1.4t | US$204.7b | -US$22,654,596,727.00 | 17.8x | -63.8x | 7.1x |
| Fri, 29 Dec 2023 | US$1.4t | US$204.9b | -US$22,192,805,164.00 | 19.9x | -62.8x | 6.8x |
| Sun, 26 Nov 2023 | US$1.2t | US$204.8b | -US$22,013,452,568.00 | 18.6x | -55.7x | 6x |
| Tue, 24 Oct 2023 | US$1.2t | US$207.5b | -US$13,040,981,709.00 | 16.2x | -93x | 5.8x |
| Thu, 21 Sep 2023 | US$1.3t | US$207.5b | -US$12,879,934,249.00 | 16.5x | -99.1x | 6.1x |
| Sat, 19 Aug 2023 | US$1.3t | US$207.6b | -US$12,299,327,844.00 | 17.4x | -102.8x | 6.1x |
| Mon, 17 Jul 2023 | US$1.1t | US$186.7b | -US$15,968,283,125.00 | 12.9x | -71.1x | 6.1x |
| Wed, 14 Jun 2023 | US$1.2t | US$186.1b | -US$15,943,311,093.00 | 11.8x | -73x | 6.3x |
| Fri, 12 May 2023 | US$1.2t | US$191.8b | -US$11,762,653,395.00 | 14.4x | -98.3x | 6x |
| Sun, 09 Apr 2023 | US$1.2t | US$216.8b | -US$5,729,497,835.00 | 14x | -203x | 5.4x |
| Tue, 07 Mar 2023 | US$1.1t | US$199.1b | -US$4,903,297,889.00 | 16x | -233.9x | 5.8x |
| Thu, 02 Feb 2023 | US$1.2t | US$204.0b | US$1.9b | 15.1x | 622.3x | 5.7x |
| Sat, 31 Dec 2022 | US$1.1t | US$203.5b | US$1.7b | 14.3x | 663.2x | 5.6x |
| Mon, 28 Nov 2022 | US$1.1t | US$202.3b | US$1.3b | 14.6x | 845.5x | 5.6x |
Price to Earnings Ratio
845.5x
Current Industry PE
- Investors are optimistic on the American Biotechs industry, and appear confident in long term growth rates.
- The 3-year average PS ratio of 6.5x is lower than the industry's current PS ratio of 7.3x.
Past Earnings Growth
- Total earnings for the Biotechs industry have declined over the last three years, with the industry now making a loss overall.
- Revenues have also declined 6.8% per year, which is driving profits down.
Industry Trends
Which industries have driven the changes within the U.S. Healthcare industry?
| US Market | -3.20% | |
| Healthcare | -0.69% | |
| Biotech | 0.97% | |
| Biotech | 0.97% | |
Industry PEThere are no additional sub-industries under this industry.
Forecasted GrowthThere are no additional sub-industries under this industry.
Top Stock Gainers and Losers
Which companies have driven the market over the last 7 days?
| Company | Last Price | 7D | 1Y | Valuation | |
|---|---|---|---|---|---|
| EXAS Exact Sciences | US$100.67 | 48.6% +US$6.2b | 89.7% | PS6.2x | |
| REGN Regeneron Pharmaceuticals | US$737.00 | 6.0% +US$4.3b | -1.0% | PE16.5x | |
| CDTX Cidara Therapeutics | US$219.55 | 107.1% +US$3.6b | 1,158.2% | PB16.3x | |
| NTRA Natera | US$225.55 | 12.4% +US$3.4b | 33.2% | PS14.7x | |
| INSM Insmed | US$199.64 | 4.5% +US$1.9b | 170.5% | PS95.2x |