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U.S. Biotech Industry Analysis

UpdatedOct 03, 2025
DataAggregated Company Financials
Companies548
  • 7D5.7%
  • 3M10.1%
  • 1Y0.1%
  • YTD11.5%

In the last week, the Biotech industry is up 5.7%, with AbbVie up 8.2%. During this same period, the MoonLake Immunotherapeutics underperformed, falling 87%. The industry has been flat over the past 12 months despite the gain this week. Earnings are forecast to grow by 25% annually.

Industry Valuation and Performance

Has the U.S. Biotech Industry valuation changed over the past few years?

DateMarket CapRevenueEarningsPEAbsolute PEPS
Fri, 03 Oct 2025US$1.1tUS$163.5b-US$18,231,777,884.7816.6x-61.3x6.8x
Sun, 31 Aug 2025US$1.1tUS$163.5b-US$18,374,916,758.5615.4x-57.4x6.5x
Tue, 29 Jul 2025US$992.7bUS$155.1b-US$22,907,102,966.3914.7x-43.3x6.4x
Thu, 26 Jun 2025US$932.5bUS$156.0b-US$23,833,808,017.7716.8x-39.1x6x
Sat, 24 May 2025US$908.4bUS$155.9b-US$24,112,206,612.1115.6x-37.7x5.8x
Mon, 21 Apr 2025US$756.9bUS$119.2b-US$36,619,881,205.0719.4x-20.7x6.3x
Wed, 19 Mar 2025US$848.7bUS$118.4b-US$37,468,766,996.5019.6x-22.6x7.2x
Fri, 14 Feb 2025US$828.4bUS$118.3b-US$35,648,753,290.5717.4x-23.2x7x
Sun, 12 Jan 2025US$947.8bUS$149.4b-US$26,263,014,335.7116.6x-36.1x6.3x
Tue, 10 Dec 2024US$1.0tUS$150.0b-US$26,481,719,164.0717.7x-39.1x6.9x
Thu, 07 Nov 2024US$1.1tUS$148.4b-US$30,716,238,423.6717.2x-35.3x7.3x
Sat, 05 Oct 2024US$879.9bUS$113.1b-US$35,952,253,973.7722x-24.5x7.8x
Mon, 02 Sep 2024US$909.4bUS$113.1b-US$35,712,101,098.3824x-25.5x8x
Wed, 31 Jul 2024US$1.2tUS$164.9b-US$28,962,809,067.1126.4x-42.6x7.5x
Fri, 28 Jun 2024US$1.1tUS$164.4b-US$27,987,328,341.4127.9x-41x7x
Sun, 26 May 2024US$1.1tUS$164.6b-US$26,653,350,594.7223.8x-42.2x6.8x
Tue, 23 Apr 2024US$1.1tUS$164.2b-US$23,311,155,066.5220.4x-45.9x6.5x
Thu, 21 Mar 2024US$1.2tUS$164.4b-US$23,861,120,065.0121.1x-48.9x7.1x
Sat, 17 Feb 2024US$1.2tUS$169.1b-US$20,461,379,458.5815.7x-57.1x6.9x
Mon, 15 Jan 2024US$1.4tUS$204.8b-US$22,497,556,941.0018.8x-63.9x7x
Wed, 13 Dec 2023US$1.3tUS$204.6b-US$22,084,753,624.0019x-59.4x6.4x
Fri, 10 Nov 2023US$1.2tUS$204.3b-US$22,786,529,302.0018.9x-54.1x6x
Sun, 08 Oct 2023US$1.3tUS$207.4b-US$13,060,168,797.0017.2x-96.3x6.1x
Tue, 05 Sep 2023US$1.3tUS$207.5b-US$12,454,516,459.0018.4x-103.9x6.2x
Thu, 03 Aug 2023US$1.1tUS$187.2b-US$14,216,380,818.0013.7x-79.9x6.1x
Sat, 01 Jul 2023US$1.1tUS$186.2b-US$16,042,400,813.0013.7x-70x6x
Mon, 29 May 2023US$1.1tUS$185.9b-US$16,045,777,796.0011.2x-69.9x6x
Wed, 26 Apr 2023US$1.2tUS$198.4b-US$3,227,872,728.0013.1x-364.9x5.9x
Fri, 24 Mar 2023US$1.1tUS$199.5b-US$3,534,604,837.0012.6x-316.2x5.6x
Sun, 19 Feb 2023US$1.2tUS$202.6b-US$64,851,937.0016.5x-17785.7x5.7x
Tue, 17 Jan 2023US$1.2tUS$203.7bUS$1.8b14.5x670.9x5.8x
Thu, 15 Dec 2022US$1.2tUS$203.0bUS$1.5b14.7x771.2x5.8x
Sat, 12 Nov 2022US$1.1tUS$201.0bUS$2.5b14.6x444x5.5x
Mon, 10 Oct 2022US$1.0tUS$206.1bUS$5.4b14.9x190.4x5x
Price to Earnings Ratio

190.4x


Total Market Cap: US$1.0tTotal Earnings: US$5.4bTotal Revenue: US$206.1bTotal Market Cap vs Earnings and Revenue0%0%0%
U.S. Biotech Industry Price to Earnings3Y Average 31.9x202320242025
Current Industry PE
  • Investors are relatively neutral on the American Biotechs industry at the moment, indicating that they anticipate long term growth rates to remain steady.
  • The industry is trading close to its 3-year average PS ratio of 6.5x.
Past Earnings Growth
  • Total earnings for the Biotechs industry have declined over the last three years, with the industry now making a loss overall.
  • Revenues have also declined 7.4% per year, which is driving profits down.

Industry Trends

Which industries have driven the changes within the U.S. Healthcare industry?

US Market1.62%
Healthcare6.37%
Biotech5.66%
Biotech5.66%
Industry PEThere are no additional sub-industries under this industry.
Forecasted GrowthThere are no additional sub-industries under this industry.

Top Stock Gainers and Losers

Which companies have driven the market over the last 7 days?

CompanyLast Price7D1YValuation
ABBV AbbVieUS$236.568.2%
+US$31.8b
21.0%PE112.2x
AMGN AmgenUS$297.409.7%
+US$14.1b
-6.3%PE24.2x
VRTX Vertex PharmaceuticalsUS$408.857.1%
+US$6.9b
-9.9%PE28.8x
REGN Regeneron PharmaceuticalsUS$600.008.0%
+US$4.6b
-40.9%PE14x
INSM InsmedUS$152.8012.7%
+US$3.6b
114.0%PS81.1x

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