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U.S. Biotech Industry Analysis

UpdatedAug 12, 2025
DataAggregated Company Financials
Companies556
  • 7D-3.4%
  • 3M10.7%
  • 1Y-7.9%
  • YTD1.4%

Over the last 7 days, the Biotech industry has dropped 3.4%, driven by a pullback from Vertex Pharmaceuticals of 21%. On the other hand Gilead Sciences is actually up 5.2%. The industry has fallen 7.9% in the last year. As for the next few years, earnings are expected to grow by 24% per annum.

Industry Valuation and Performance

Has the U.S. Biotech Industry valuation changed over the past few years?

DateMarket CapRevenueEarningsPEAbsolute PEPS
Tue, 12 Aug 2025US$1.0tUS$163.2b-US$15,403,535,856.8814.3x-66.2x6.2x
Thu, 10 Jul 2025US$959.7bUS$155.8b-US$23,411,293,319.8218.2x-41x6.2x
Sat, 07 Jun 2025US$931.9bUS$155.9b-US$23,945,759,591.2516.8x-38.9x6x
Mon, 05 May 2025US$959.6bUS$153.8b-US$24,601,947,084.6619.7x-39x6.2x
Wed, 02 Apr 2025US$796.3bUS$118.6b-US$37,136,248,113.9221.4x-21.4x6.7x
Fri, 28 Feb 2025US$843.5bUS$118.6b-US$37,303,235,811.0217x-22.6x7.1x
Sun, 26 Jan 2025US$981.2bUS$149.5b-US$26,320,970,275.6817.2x-37.3x6.6x
Tue, 24 Dec 2024US$956.2bUS$149.9b-US$26,388,997,522.1915.3x-36.2x6.4x
Thu, 21 Nov 2024US$989.6bUS$150.0b-US$26,776,308,908.7316.8x-37x6.6x
Sat, 19 Oct 2024US$909.8bUS$113.1b-US$35,980,542,500.0221.7x-25.3x8x
Mon, 16 Sep 2024US$932.2bUS$113.2b-US$36,059,145,110.5923.4x-25.9x8.2x
Wed, 14 Aug 2024US$861.0bUS$113.0b-US$36,639,604,267.0422.7x-23.5x7.6x
Fri, 12 Jul 2024US$1.2tUS$164.5b-US$28,077,075,512.8029.6x-41.5x7.1x
Sun, 09 Jun 2024US$1.2tUS$164.5b-US$26,798,622,131.2128.1x-43.1x7x
Tue, 07 May 2024US$1.1tUS$162.6b-US$27,558,558,120.2427.4x-40.8x6.9x
Thu, 04 Apr 2024US$1.1tUS$164.3b-US$23,560,093,353.1223.5x-48.7x7x
Sat, 02 Mar 2024US$1.2tUS$167.9b-US$21,266,980,809.7515.9x-55.4x7x
Mon, 29 Jan 2024US$1.4tUS$204.7b-US$22,652,938,045.0018.3x-63.1x7x
Wed, 27 Dec 2023US$1.4tUS$204.9b-US$22,191,084,128.0019.6x-61.8x6.7x
Fri, 24 Nov 2023US$1.2tUS$204.7b-US$22,047,730,821.0018x-55.3x6x
Sun, 22 Oct 2023US$1.2tUS$207.4b-US$13,088,260,702.0016.6x-93.6x5.9x
Tue, 19 Sep 2023US$1.3tUS$207.5b-US$12,859,693,014.0017.2x-99.5x6.2x
Thu, 17 Aug 2023US$1.3tUS$207.7b-US$12,321,742,893.0017.7x-103.2x6.1x
Sat, 15 Jul 2023US$1.1tUS$186.7b-US$15,944,193,566.0013.3x-71.2x6.1x
Mon, 12 Jun 2023US$1.1tUS$186.0b-US$15,970,598,297.0011.7x-71.6x6.2x
Wed, 10 May 2023US$1.2tUS$192.6b-US$11,459,990,654.0014.5x-101.7x6x
Fri, 07 Apr 2023US$1.2tUS$216.9b-US$5,766,366,754.0014.5x-201.7x5.4x
Sun, 05 Mar 2023US$1.2tUS$199.0b-US$4,964,241,359.0016.5x-232.2x5.8x
Tue, 31 Jan 2023US$1.2tUS$203.7bUS$1.7b14.6x660.8x5.7x
Thu, 29 Dec 2022US$1.1tUS$203.3bUS$1.6b14.2x689x5.5x
Sat, 26 Nov 2022US$1.1tUS$202.3bUS$1.3b14.6x845.6x5.6x
Mon, 24 Oct 2022US$1.1tUS$206.2bUS$5.3b15.8x200.9x5.2x
Wed, 21 Sep 2022US$1.1tUS$206.6bUS$5.8b14.4x180x5.1x
Fri, 19 Aug 2022US$1.1tUS$206.6bUS$7.3b16.2x148.6x5.3x
Price to Earnings Ratio

148.6x


Total Market Cap: US$1.1tTotal Earnings: US$7.3bTotal Revenue: US$206.6bTotal Market Cap vs Earnings and Revenue0%0%0%
U.S. Biotech Industry Price to Earnings3Y Average 42.7x202320242025
Current Industry PE
  • Investors are relatively neutral on the American Biotechs industry at the moment, indicating that they anticipate long term growth rates to remain steady.
  • The industry is trading close to its 3-year average PS ratio of 6.4x.
Past Earnings Growth
  • Total earnings for the Biotechs industry have declined over the last three years, with the industry now making a loss overall.
  • Revenues have also declined 7.6% per year, which is driving profits down.

Industry Trends

Which industries have driven the changes within the U.S. Healthcare industry?

US Market0.73%
Healthcare-2.34%
Biotech-3.37%
Biotech-3.37%
Industry PEThere are no additional sub-industries under this industry.
Forecasted GrowthThere are no additional sub-industries under this industry.

Top Stock Gainers and Losers

Which companies have driven the market over the last 7 days?

CompanyLast Price7D1YValuation
GILD Gilead SciencesUS$120.475.2%
+US$7.0b
65.1%PE23.7x
NTRA NateraUS$157.0415.0%
+US$2.9b
36.3%PS11x
INSM InsmedUS$112.891.5%
+US$2.7b
52.4%PS59.9x
ABBV AbbVieUS$198.640.7%
+US$2.6b
4.4%PE94.3x
ALNY Alnylam PharmaceuticalsUS$435.003.7%
+US$2.0b
61.0%PS23.2x

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