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U.S. Biotech Industry Analysis

UpdatedMay 18, 2025
DataAggregated Company Financials
Companies564
  • 7D3.7%
  • 3M-10.1%
  • 1Y-14.5%
  • YTD-7.1%

Regeneron Pharmaceuticals is up 13%, leading the way for the Biotech industry, which has gained 3.7%. Meanwhile, Halozyme Therapeutics actually underperformed within the industry, shrinking 21% in the last week. In the past year, the industry is down 14%. Looking forward, earnings are forecast to grow by 24% annually.

Industry Valuation and Performance

Has the U.S. Biotech Industry valuation changed over the past few years?

DateMarket CapRevenueEarningsPEAbsolute PEPS
Sun, 18 May 2025US$895.3bUS$155.9b-US$24,392,718,921.6016.3x-36.7x5.7x
Tue, 15 Apr 2025US$740.5bUS$119.2b-US$36,459,397,381.9019.9x-20.3x6.2x
Thu, 13 Mar 2025US$834.6bUS$118.7b-US$37,659,545,163.6818.4x-22.2x7x
Sat, 08 Feb 2025US$857.1bUS$117.3b-US$30,948,989,158.0417.2x-27.7x7.3x
Mon, 06 Jan 2025US$980.2bUS$149.6b-US$26,354,792,434.1217x-37.2x6.6x
Wed, 04 Dec 2024US$1.0tUS$149.9b-US$26,584,927,055.4016.5x-39.1x6.9x
Fri, 01 Nov 2024US$1.1tUS$147.3b-US$30,454,139,694.2717.1x-34.7x7.2x
Sun, 29 Sep 2024US$893.6bUS$113.2b-US$36,006,680,210.7121.3x-24.8x7.9x
Tue, 27 Aug 2024US$909.0bUS$113.1b-US$35,851,266,005.4623.3x-25.4x8x
Thu, 25 Jul 2024US$1.2tUS$164.5b-US$28,090,976,401.9328.2x-43x7.3x
Sat, 22 Jun 2024US$1.1tUS$164.4b-US$27,943,646,272.0028.1x-41.1x7x
Mon, 20 May 2024US$1.1tUS$164.6b-US$26,835,738,666.6423.9x-42.8x7x
Wed, 17 Apr 2024US$1.1tUS$164.2b-US$23,402,696,044.0520.5x-46.3x6.6x
Fri, 15 Mar 2024US$1.2tUS$167.4b-US$22,100,849,384.5416.3x-54.1x7.1x
Sun, 11 Feb 2024US$1.2tUS$169.3b-US$26,263,046,791.8719.8x-44.2x6.9x
Tue, 09 Jan 2024US$1.4tUS$204.8b-US$22,499,844,981.0020.8x-63.1x6.9x
Thu, 07 Dec 2023US$1.3tUS$204.6b-US$22,056,080,007.0019.4x-58.1x6.3x
Sat, 04 Nov 2023US$1.2tUS$206.7b-US$20,531,174,316.0018.8x-60.4x6x
Mon, 02 Oct 2023US$1.3tUS$207.4b-US$13,122,605,528.0017.1x-95.8x6.1x
Wed, 30 Aug 2023US$1.3tUS$207.6b-US$12,432,896,963.0017.8x-103.8x6.2x
Fri, 28 Jul 2023US$1.1tUS$186.8b-US$16,232,166,533.0014.3x-69.6x6x
Sun, 25 Jun 2023US$1.1tUS$186.2b-US$16,162,116,001.0013.6x-70.3x6.1x
Tue, 23 May 2023US$1.2tUS$186.0b-US$15,902,975,009.0013.3x-72.9x6.2x
Thu, 20 Apr 2023US$1.2tUS$198.4b-US$3,264,741,817.0013.6x-362.5x6x
Sat, 18 Mar 2023US$1.1tUS$199.2b-US$3,900,694,523.0013.2x-286.4x5.6x
Mon, 13 Feb 2023US$1.2tUS$202.7b-US$211,129,546.0016.4x-5476.8x5.7x
Wed, 11 Jan 2023US$1.2tUS$203.5bUS$1.7b14.1x695.4x5.7x
Fri, 09 Dec 2022US$1.2tUS$202.7bUS$1.4b14.9x819.9x5.8x
Sun, 06 Nov 2022US$1.1tUS$204.6bUS$3.6b14.2x299.5x5.3x
Tue, 04 Oct 2022US$1.0tUS$206.2bUS$5.5b14.6x189.3x5x
Thu, 01 Sep 2022US$1.0tUS$206.4bUS$7.3b14.1x140x5x
Sat, 30 Jul 2022US$1.1tUS$212.0bUS$11.3b15.6x93.2x5x
Mon, 27 Jun 2022US$1.1tUS$212.4bUS$11.1b15.4x95.1x4.9x
Wed, 25 May 2022US$992.4bUS$212.8bUS$11.1b15.7x89.2x4.7x
Price to Earnings Ratio

89.2x


Total Market Cap: US$992.4bTotal Earnings: US$11.1bTotal Revenue: US$212.8bTotal Market Cap vs Earnings and Revenue0%0%0%
U.S. Biotech Industry Price to Earnings3Y Average 53.8x202320242025
Current Industry PE
  • Investors are relatively neutral on the American Biotechs industry at the moment, indicating that they anticipate long term growth rates to remain steady.
  • The industry is trading close to its 3-year average PS ratio of 6.3x.
Past Earnings Growth
  • Total earnings for the Biotechs industry have declined over the last three years, with the industry now making a loss overall.
  • Revenues have also declined 9.9% per year, which is driving profits down.

Industry Trends

Which industries have driven the changes within the U.S. Healthcare industry?

US Market5.34%
Healthcare0.68%
Biotech3.71%
Biotech3.71%
Industry PEThere are no additional sub-industries under this industry.
Forecasted GrowthThere are no additional sub-industries under this industry.

Top Stock Gainers and Losers

Which companies have driven the market over the last 7 days?

CompanyLast Price7D1YValuation
REGN Regeneron PharmaceuticalsUS$594.3212.6%
+US$7.0b
-39.5%PE14x
GILD Gilead SciencesUS$102.505.8%
+US$7.0b
51.4%PE21.4x
ALNY Alnylam PharmaceuticalsUS$285.3113.6%
+US$4.5b
91.0%PS15.8x
AMGN AmgenUS$272.412.5%
+US$3.5b
-12.8%PE24.7x
VRTX Vertex PharmaceuticalsUS$438.653.2%
+US$3.5b
-1.5%PS10.1x
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Latest News

EXEL

US$45.40

Exelixis

7D

25.5%

1Y

117.1%

TVTX

US$16.80

Travere Therapeutics

7D

-16.1%

1Y

177.2%

AMGN

US$272.41

Amgen

7D

2.5%

1Y

-12.8%

BHVN

US$16.02

Biohaven

7D

-20.8%

1Y

-57.1%

RVMD

US$39.54

Revolution Medicines

7D

-2.2%

1Y

0.3%

LEGN

US$27.78

Legend Biotech

7D

-12.6%

1Y

-38.5%

HALO

US$52.02

Halozyme Therapeutics

7D

-21.0%

1Y

16.3%

REGN

US$594.32

Regeneron Pharmaceuticals

7D

12.6%

1Y

-39.5%

ALNY

US$285.31

Alnylam Pharmaceuticals

7D

13.6%

1Y

91.0%

EXAS

US$56.42

Exact Sciences

7D

9.3%

1Y

12.0%

VRTX

US$438.65

Vertex Pharmaceuticals

7D

3.2%

1Y

-1.5%

BIIB

US$125.59

Biogen

7D

6.3%

1Y

-45.5%