NasdaqGM:NTLABiotechs
Why Intellia Therapeutics (NTLA) Is Down 12.6% After FDA Lifts Hold On Key CRISPR Trial
In late January 2026, Intellia Therapeutics announced that the FDA removed the clinical hold on its MAGNITUDE-2 Phase 3 trial of CRISPR-based therapy nexiguran ziclumeran for hereditary transthyretin amyloidosis with polyneuropathy, allowing patient enrollment and dosing to resume under enhanced liver safety monitoring and a slightly expanded enrollment target.
This decision marks a key regulatory step for Intellia’s in vivo gene-editing program, highlighting both the promise of a one-time...