Denali Therapeutics Inc.

NasdaqGS:DNLI Voorraadrapport

Marktkapitalisatie: US$4.0b

Denali Therapeutics Toekomstige groei

Future criteriumcontroles 2/6

Denali Therapeutics zal naar verwachting groeien in winst en omzet met respectievelijk 26.8% en 53% per jaar. De winst per aandeel zal naar verwachting groeien met 29.6% per jaar. Het rendement op het eigen vermogen zal over 3 jaar naar verwachting -59.1% zijn.

Belangrijke informatie

26.8%

Groei van de winst

29.56%

Groei van de winst per aandeel

Biotechs winstgroei27.7%
Inkomstengroei53.0%
Toekomstig rendement op eigen vermogen-59.11%
Dekking van analisten

Good

Laatst bijgewerkt11 Aug 2026

Recente toekomstige groei-updates

Recent updates

Nieuw narratief Aug 21

Blood Brain Barrier Platform And Rare Disease Pipeline Will Shape Long Term Neurology Potential

Catalysts About Denali Therapeutics Denali Therapeutics develops biologic medicines designed to cross the blood brain barrier for rare genetic and common neurodegenerative diseases. What are the underlying business or industry changes driving this perspective?
Seeking Alpha Aug 13

Denali Therapeutics: AVLAYAH Converts A Platform Story Into A Commercial One

Summary Denali Therapeutics (DNLI) is transitioning from a neuroscience platform to a commercial biotech with AVLAYAH, its FDA-approved rare-disease therapy. AVLAYAH's Q2 revenue of $3.6M is projected to triple in Q3, reflecting accelerating patient uptake and payer coverage progress. DNLI's TransportVehicle platform underpins a pipeline spanning enzymes, antibodies, and oligonucleotides, targeting both rare and large neurodegenerative markets. Valuation requires execution: AVLAYAH's commercial ramp and zafinofusp alfa's progress are critical, while Alzheimer’s programs offer significant long-term optionality. Read the full article on Seeking Alpha
Nieuw narratief Aug 07

Brain Delivery Platform And Rare Disease Portfolio Will Support Long-Term Upside Potential

Catalysts About Denali Therapeutics Denali Therapeutics focuses on biologic medicines engineered to cross the blood brain barrier for rare genetic and common neurodegenerative diseases. What are the underlying business or industry changes driving this perspective?
Analyse-artikel May 08

We're Not Very Worried About Denali Therapeutics' (NASDAQ:DNLI) Cash Burn Rate

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Seeking Alpha Mar 20

Denali Therapeutics: Vast Pipeline, First Approval Up Ahead

Summary Denali Therapeutics' stock has significantly dropped from $100 to $15 since 2021, but the company is now heavily derisked with promising product candidates nearing key milestones. Lead asset DNL310 shows strong biomarker data for Hunter syndrome, with plans for a BLA submission and accelerated approval by Q2 2025. The Biogen partnership for Parkinson’s Disease asset DNL151 includes substantial milestone payments and profit-sharing, highlighting its potential impact. Despite past failures, Denali's extensive pipeline and solid financial runway make it a compelling buy at current low stock prices. Read the full article on Seeking Alpha
Seeking Alpha Jan 09

Denali: Despite ALS Primary Endpoint Failure, Possible Path Forward Remains

Summary Denali Therapeutics Inc.'s DNL343 failed to meet the primary endpoint in the phase 2/3 HEALY ALS trial, but potential biomarker analyses in 2025 may offer a path forward. Despite the trial setback in ALS, Denali's stock remains stable due to continued pre-specified analyses expected in late 2025. BLA filing of tividenofusp alfa for the treatment of patients with MPS II remains on track under the Accelerated Approval Pathway Program in early 2025. Financially, Denali has $1.28 billion in cash but may need additional funding in 2025, posing a risk of shareholder dilution. Read the full article on Seeking Alpha
Analyse-artikel Dec 09

We're Hopeful That Denali Therapeutics (NASDAQ:DNLI) Will Use Its Cash Wisely

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...
Seeking Alpha Aug 20

Denali Therapeutics: A Promising Biotech With Revolutionary BBB-Crossing Technology

Summary Denali Therapeutics' proprietary Transport Vehicle technology enables drug delivery across the blood-brain barrier, targeting neurodegenerative diseases. DNL310, targeting MPS II, and DNL343 for ALS are key drug candidates with potential, though competition is significant. The company’s $500 million capital raise supports its aggressive R&D investment, providing a runway for developing its pipeline. Despite its promising platform, DNLI still has a relatively high cash burn and regulatory hurdles before achieving drug approval. Due to Denali's high-risk, long-term biotech development, I deem DNLI a DCA "buy" for investors who understand the inherent risks. Read the full article on Seeking Alpha
Analyse-artikel Jul 26

Companies Like Denali Therapeutics (NASDAQ:DNLI) Are In A Position To Invest In Growth

Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...
Analyse-artikel May 23

Revenues Not Telling The Story For Denali Therapeutics Inc. (NASDAQ:DNLI) After Shares Rise 25%

Denali Therapeutics Inc. ( NASDAQ:DNLI ) shareholders would be excited to see that the share price has had a great...
Seeking Alpha May 13

Denali Therapeutics: MPS Treatment Program Continues With End Of 2024 Data

Summary Denali Therapeutics Inc.'s DNL-310 is currently being explored in an ongoing phase 2/3 COMPASS study for treatment of patients with MPS II; Enrollment completion expected in 2024. Denali is in talks with CDER division of FDA to seek for Accelerated Approval pathway for DNL-310 for the treatment of patients with MPS II. Biomarker and safety data from a phase 1/2 study, using DNL-126 for the treatment of patients with MPS IIIA, expected end of 2024. Another promising program from the pipeline is the development of DNL-343, which is being advanced in the phase 2/3 HEALEY ALS Platform trial for treatment of patients with amyotrophic lateral sclerosis. Read the full article on Seeking Alpha
Analyse-artikel Apr 17

An Intrinsic Calculation For Denali Therapeutics Inc. (NASDAQ:DNLI) Suggests It's 44% Undervalued

Key Insights Using the 2 Stage Free Cash Flow to Equity, Denali Therapeutics fair value estimate is US$30.71 Denali...
Analyse-artikel Mar 21

Denali Therapeutics Inc.'s (NASDAQ:DNLI) Price Is Right But Growth Is Lacking After Shares Rocket 25%

Those holding Denali Therapeutics Inc. ( NASDAQ:DNLI ) shares would be relieved that the share price has rebounded 25...
Seeking Alpha Mar 07

Denali: Leveraging Transport Vehicle Technology For Neurological Gains

Summary Denali's stock performance has been flat despite the biotech sector's 20% rise; recently raised $500 million in a PIPE. ALS trial failure with partner Sanofi pressured stock; Denali's focus is on transport vehicle (TV) technology and BBB crossing. Denali boasts a strong financial position with $1.53 billion in cash, extending operational runway significantly. Recommends "buy" based on Denali's innovative TV technology, financial health, and potential in neurological disorders despite biotech risks. Read the full article on Seeking Alpha
Analyse-artikel Feb 21

Companies Like Denali Therapeutics (NASDAQ:DNLI) Are In A Position To Invest In Growth

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...
Analyse-artikel Jan 26

Improved Revenues Required Before Denali Therapeutics Inc. (NASDAQ:DNLI) Shares Find Their Feet

Denali Therapeutics Inc.'s ( NASDAQ:DNLI ) price-to-sales (or "P/S") ratio of 7x might make it look like a buy right...
Analyse-artikel Nov 20

We're Not Very Worried About Denali Therapeutics' (NASDAQ:DNLI) Cash Burn Rate

Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...
Analyse-artikel Oct 09

Investor Optimism Abounds Denali Therapeutics Inc. (NASDAQ:DNLI) But Growth Is Lacking

With a median price-to-sales (or "P/S") ratio of close to 10.4x in the Biotechs industry in the United States, you...

Winst- en omzetgroeiprognoses

NasdaqGS:DNLI - Toekomstschattingen van analisten en financiële gegevens uit het verleden (USD Millions )
DatumInkomstenInkomstenVrije kasstroomGeldmiddelen uit operationele activiteitenGem. Aantal analisten
12/31/2028310-375-22-17315
12/31/2027129-4538-34919
12/31/202661-452-433-33019
6/30/20264-511-466-434N/A
3/31/2026N/A-508-419-412N/A
12/31/2025N/A-513-422-413N/A
9/30/2025N/A-499-411-398N/A
6/30/2025N/A-479-368-350N/A
3/31/2025N/A-454-384-366N/A
12/31/2024N/A-423-364-348N/A
9/30/2024N/A-427-376-363N/A
6/30/20241-420-402-391N/A
3/31/2024295-137-425-413N/A
12/31/2023331-145-371-358N/A
9/30/2023341-124-348-332N/A
6/30/2023343-128-321-302N/A
3/31/2023101-371-248-231N/A
12/31/2022108-326-263-245N/A
9/30/2022111-303-254-238N/A
6/30/2022112-284-234-222N/A
3/31/202283-286-243-233N/A
12/31/202149-291-220-211N/A
9/30/202135330361368N/A
6/30/202135756404410N/A
3/31/202134058415420N/A
12/31/202033671413416N/A
9/30/202024-228-150-145N/A
6/30/202028-216-183-176N/A
3/31/202026-215N/A-176N/A
12/31/201927-198N/A-152N/A
9/30/2019148-66N/A-11N/A
6/30/2019135-55N/A-15N/A
3/31/2019133-52N/A-14N/A
12/31/2018129-36N/A50N/A
9/30/20183-137N/A-61N/A
6/30/20182-123N/A-49N/A
3/31/20181-91N/A-24N/A
12/31/2017N/A-88N/A-77N/A
9/30/2017N/A-85N/A-77N/A
6/30/2017N/A-93N/A-76N/A
3/31/2017N/A-90N/A-75N/A
12/31/2016N/A-87N/A-72N/A

Toekomstige groeivoorspellingen analisten

Verdiensten versus spaarpercentage: De verwachting is dat DNLI de komende 3 jaar verliesgevend zal blijven.

Winst versus markt: De verwachting is dat DNLI de komende 3 jaar verliesgevend zal blijven.

Hoge groeiwinsten: De verwachting is dat DNLI de komende 3 jaar verliesgevend zal blijven.

Omzet versus markt: De omzet van DNLI ( 53% per jaar) zal naar verwachting sneller groeien dan de markt US ( 12.9% per jaar).

Hoge groei-inkomsten: De omzet van DNLI ( 53% per jaar) zal naar verwachting sneller groeien dan 20% per jaar.


Groeiprognoses winst per aandeel


Toekomstig rendement op eigen vermogen

Toekomstige ROE: Er wordt voorspeld dat DNLI binnen 3 jaar verliesgevend zal zijn.


Ontdek groeibedrijven

Bedrijfsanalyse en status van financiële gegevens

GegevensLaatst bijgewerkt (UTC-tijd)
Bedrijfsanalyse2026/08/21 10:09
Aandelenkoers aan het einde van de dag2026/08/21 00:00
Inkomsten2026/06/30
Jaarlijkse inkomsten2025/12/31

Gegevensbronnen

De gegevens die gebruikt zijn in onze bedrijfsanalyse zijn afkomstig van S&P Global Market Intelligence LLC. De volgende gegevens worden gebruikt in ons analysemodel om dit rapport te genereren. De gegevens zijn genormaliseerd, waardoor er een vertraging kan optreden voordat de bron beschikbaar is.

PakketGegevensTijdframeVoorbeeld Amerikaanse bron *
Financiële gegevens bedrijf10 jaar
  • Resultatenrekening
  • Kasstroomoverzicht
  • Balans
Consensus schattingen analisten+3 jaar
  • Financiële prognoses
  • Koersdoelen analisten
Marktprijzen30 jaar
  • Aandelenprijzen
  • Dividenden, splitsingen en acties
Eigendom10 jaar
  • Top aandeelhouders
  • Handel met voorkennis
Beheer10 jaar
  • Leiderschapsteam
  • Raad van bestuur
Belangrijkste ontwikkelingen10 jaar
  • Bedrijfsaankondigingen

* Voorbeeld voor effecten uit de VS, voor niet-Amerikaanse effecten worden gelijkwaardige formulieren en bronnen gebruikt.

Tenzij anders vermeld zijn alle financiële gegevens gebaseerd op een jaarperiode, maar worden ze elk kwartaal bijgewerkt. Dit staat bekend als Trailing Twelve Month (TTM) of Last Twelve Month (LTM) gegevens. Meer informatie.

Analysemodel en Snowflake

Details van het analysamodel dat is gebruikt om dit rapport te genereren zijn beschikbaar op onze Github-pagina, we hebben ook handleidingen over hoe u onze rapporten kunt gebruiken en tutorials op YouTube.

Leer meer over het team van wereldklasse dat het Simply Wall St-analysemodel heeft ontworpen en gebouwd.

Industrie en sector

Onze industrie- en sectormetrics worden elke 6 uur berekend door Simply Wall St, details van ons proces zijn beschikbaar op Github.

Bronnen van analisten

Denali Therapeutics Inc. wordt gevolgd door 33 analisten. 19 van deze analisten hebben de schattingen van de omzet of winst ingediend die zijn gebruikt als input voor ons rapport. Inzendingen van analisten worden de hele dag door bijgewerkt.

AnalistInstelling
null nullBaird
Joel BeattyBaird
Charles MooreBaird