U.S. Pharmaceuticals & Biotech Leverage Leaders

SELLAS Life Sciences Group

Market Cap: US$2.4b

A late-stage clinical biopharmaceutical company, focuses on the development of novel therapeutics for various cancer indications in the United States.

Celldex Therapeutics

Market Cap: US$2.7b

A biopharmaceutical company, engages in developing therapeutic antibodies for patients with severe inflammatory, allergic, autoimmune, and other diseases.

Harmony Biosciences Holdings

Market Cap: US$2.0b

A commercial-stage pharmaceutical company, focuses on developing and commercializing therapies for patients with rare neurological diseases in the United States.

West Pharmaceutical Services

Market Cap: US$25.3b

Designs, manufactures, and sells containment and delivery systems for injectable drugs and healthcare products in the Americas, Europe, the Middle East, Africa, and the Asia Pacific.

Relay Therapeutics

Market Cap: US$4.2b

Operates as a clinical-stage precision medicines company.

Veracyte

Market Cap: US$4.6b

Operates as a diagnostics company in the United States and internationally.

Pharvaris

Market Cap: US$2.4b

A late-stage biopharmaceutical company, focuses on the development and commercialization of therapies for rare diseases with unmet needs covering angioedema and other bradykinin-mediated diseases.

BioMarin Pharmaceutical

Market Cap: US$11.3b

A biotechnology company, engages in the development and commercialization of therapies for life-threatening rare diseases and medical conditions in the United States, Europe, Latin America, the Middle East, the Asia Pacific, and internationally.

Alumis

Market Cap: US$3.7b

A clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disorders.

Immunovant

Market Cap: US$8.0b

A clinical-stage immunology company, develops targeted therapies to meet the needs of people with autoimmune diseases.

Hemab Therapeutics Holdings

Market Cap: US$2.3b

Operates as a clinical-stage biotechnology company developing therapies that reimagine the treatment of blood coagulation disorders to sustain life and human resilience in United States of America and Denmark.

Kymera Therapeutics

Market Cap: US$9.1b

A clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics that selectively degrade disease-causing proteins by harnessing the body’s own natural protein degradation system.

Natera

Market Cap: US$37.8b

A diagnostics company, engages in the development and commercialization of molecular testing services worldwide.

Edgewise Therapeutics

Market Cap: US$4.1b

A biopharmaceutical company, discovers, develops, and commercializes therapies for the treatment of muscle disorders.

10x Genomics

Market Cap: US$6.0b

Develops and sells instruments, consumables, and software for analyzing biological systems in the United States, rest of the Americas, Europe, the Middle East, Africa, China, and the rest of the Asia Pacific.

Kardigan

Market Cap: US$2.0b

Operates as a biopharmaceutical company focused on developing medicines for cardiovascular diseases.

Regencell Bioscience Holdings

Market Cap: US$3.0b

Operates as a Traditional Chinese medicine (TCM) bioscience company in Hong Kong.

BioNTech

Market Cap: US$23.2b

Engages in the development and commercialization of immunotherapies in Germany.

Kodiak Sciences

Market Cap: US$2.6b

A clinical stage biopharmaceutical company, engages in the research, development, and commercialization of therapeutics to treat retinal diseases.

Medpace Holdings

Market Cap: US$14.7b

Provides clinical research-based drug and medical device development services in North America, Europe, Asia, South America, Africa, and Australia.

Beam Therapeutics

Market Cap: US$2.7b

A biotechnology company, engages in the development of precision genetic medicines for patients suffering from serious diseases in the United States.

Parabilis Medicines

Market Cap: US$3.9b

Operates as a clinical-stage biopharmaceutical company focused on developing helical peptide therapeutics for disease treatment.

IDEAYA Biosciences

Market Cap: US$3.3b

A precision medicine oncology company, develops targeted therapeutics for patient populations selected using molecular diagnostics in the United States.

NewAmsterdam Pharma

Market Cap: US$3.7b

A late-stage biopharmaceutical company, develops therapies to enhance patient care in populations with cardiometabolic disease.

Xenon Pharmaceuticals

Market Cap: US$6.4b

A neuroscience-focused biopharmaceutical company, engages in the discovery, development, and delivery of therapeutics to treat patients with neurological and psychiatric disorders.

Belite Bio

Market Cap: US$6.2b

A clinical stage biopharmaceutical drug development company, engages in the research and development of novel therapeutics with unmet medical needs in the United States.

Repligen

Market Cap: US$7.9b

A life sciences company, develops and commercializes bioprocessing technologies and systems in North America, Europe, the Asia Pacific, and internationally.

Praxis Precision Medicines

Market Cap: US$8.7b

A clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance in the United States.

Tango Therapeutics

Market Cap: US$4.1b

A precision oncology company, focuses on the discovery and development of drugs in defined patient populations with unmet medical need.

Iovance Biotherapeutics

Market Cap: US$2.3b

A commercial-stage biopharmaceutical company, develops and commercializes cell therapies using autologous tumor infiltrating lymphocyte for the treatment of metastatic melanoma and other solid tumor cancers in the United States and internationally.

Immunome

Market Cap: US$2.6b

A biotechnology company, engages in the discovery, design, development, manufacturing, and commercialization of antibody-drug conjugates and other oncology therapeutics in the United States.

Denali Therapeutics

Market Cap: US$3.8b

A biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases.

Kailera Therapeutics

Market Cap: US$2.3b

Operates as a clinical-stage biopharmaceutical company developing therapies for obesity and related conditions.

Bio-Rad Laboratories

Market Cap: US$8.2b

Develops, manufactures, and distributes life science research and clinical diagnostic products in the United States, Europe, Asia, Canada, Latin America, and internationally.

BeOne Medicines

Market Cap: US$35.6b

An oncology company, engages in discovering and developing various treatments for cancer patients in the United States, China, Europe, and internationally.

Mineralys Therapeutics

Market Cap: US$2.4b

A biopharmaceutical company, develops medicines to target diseases driven by dysregulated aldosterone in the United States.