Snowflake Score | |
---|---|
Valuation | 2/6 |
Future Growth | 2/6 |
Past Performance | 0/6 |
Financial Health | 6/6 |
Dividends | 0/6 |
DNLI Stock Overview
Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutic candidates for neurodegenerative diseases in the United States.
Denali Therapeutics Competitors
Price History & Performance
Historical stock prices | |
---|---|
Current Share Price | US$29.30 |
52 Week High | US$79.70 |
52 Week Low | US$20.24 |
Beta | 1.89 |
1 Month Change | 16.13% |
3 Month Change | -9.57% |
1 Year Change | -61.89% |
3 Year Change | 42.86% |
5 Year Change | n/a |
Change since IPO | 36.60% |
Recent News & Updates
We're Not Very Worried About Denali Therapeutics' (NASDAQ:DNLI) Cash Burn Rate
Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Shareholder Returns
DNLI | US Biotechs | US Market | |
---|---|---|---|
7D | 9.5% | 10.3% | 6.3% |
1Y | -61.9% | -24.5% | -18.8% |
Return vs Industry: DNLI underperformed the US Biotechs industry which returned -24.5% over the past year.
Return vs Market: DNLI underperformed the US Market which returned -18.8% over the past year.
Price Volatility
DNLI volatility | |
---|---|
DNLI Average Weekly Movement | 11.2% |
Biotechs Industry Average Movement | 13.2% |
Market Average Movement | 8.1% |
10% most volatile stocks in US Market | 16.7% |
10% least volatile stocks in US Market | 3.2% |
Stable Share Price: DNLI is not significantly more volatile than the rest of US stocks over the past 3 months, typically moving +/- 11% a week.
Volatility Over Time: DNLI's weekly volatility (11%) has been stable over the past year.
About the Company
Founded | Employees | CEO | Website |
---|---|---|---|
2013 | 380 | Ryan Watts | https://www.denalitherapeutics.com |
Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutic candidates for neurodegenerative diseases in the United States. It offers leucine-rich repeat kinase 2 (LRRK2) inhibitor product candidate, including BIIB122/DNL151, a small molecule inhibitor, which is in phase I and phase Ib clinical trials for the treatment of Parkinson’s disease. The company also develops DNL310 that is in Phase I/II clinical trials for the treatment of hunter syndrome; DNL343, which is in phase 1 clinical trial the treatment of amyotrophic lateral sclerosis (ALS); AR443820/DNL788 completed a phase I clinical trial for the treatment of ALS, multiple sclerosis (MS), and Alzheimer’s disease; and SAR443122/DNL758, which is in phase II clinical trial for the treatment of cutaneous lupus erythematosus.
Denali Therapeutics Fundamentals Summary
DNLI fundamental statistics | |
---|---|
Market Cap | US$3.60b |
Earnings (TTM) | -US$285.76m |
Revenue (TTM) | US$82.88m |
43.5x
P/S Ratio-12.6x
P/E RatioIs DNLI overvalued?
See Fair Value and valuation analysisEarnings & Revenue
DNLI income statement (TTM) | |
---|---|
Revenue | US$82.88m |
Cost of Revenue | US$291.24m |
Gross Profit | -US$208.36m |
Other Expenses | US$77.40m |
Earnings | -US$285.76m |
Last Reported Earnings
Mar 31, 2022
Next Earnings Date
n/a
Earnings per share (EPS) | -2.32 |
Gross Margin | -251.41% |
Net Profit Margin | -344.79% |
Debt/Equity Ratio | 0% |
How did DNLI perform over the long term?
See historical performance and comparisonValuation
Is DNLI undervalued compared to its fair value, analyst forecasts and its price relative to the market?
Valuation Score
2/6Valuation Score 2/6
Price-To-Sales vs Peers
Price-To-Sales vs Industry
Price-To-Sales vs Fair Ratio
Below Fair Value
Significantly Below Fair Value
PEG Ratio
Key Valuation Metric
Which metric is best to use when looking at relative valuation for DNLI?
Other financial metrics that can be useful for relative valuation.
What is DNLI's n/a Ratio? | |
---|---|
n/a Ratio | 0x |
n/a | n/a |
Market Cap | US$3.60b |
Key Statistics | |
---|---|
Enterprise Value/Revenue | 29.6x |
Enterprise Value/EBITDA | -8.7x |
PEG Ratio | n/a |
Price to Sales Ratio vs Peers
How does DNLI's PS Ratio compare to its peers?
DNLI PS Ratio vs Peers |
---|
Company | PS | Estimated Growth | Market Cap |
---|---|---|---|
Peer Average | 20.5x | ||
CYTK Cytokinetics | 62.3x | 66.3% | US$4.2b |
NTRA Natera | 5.4x | 18.3% | US$3.6b |
FOLD Amicus Therapeutics | 9.3x | 25.0% | US$3.0b |
PTCT Therapeutics | 5x | 10.6% | US$2.8b |
DNLI Denali Therapeutics | 43.5x | 52.5% | US$3.6b |
Price-To-Sales vs Peers: DNLI is expensive based on its Price-To-Sales Ratio (43.5x) compared to the peer average (20.5x).
Price to Earnings Ratio vs Industry
How does DNLI's PE Ratio compare vs other companies in the US Biotechs Industry?
Price-To-Sales vs Industry: DNLI is expensive based on its Price-To-Sales Ratio (43.5x) compared to the US Biotechs industry average (13.7x)
Price to Sales Ratio vs Fair Ratio
What is DNLI's PS Ratio compared to its Fair PS Ratio? This is the expected PS Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.
Fair Ratio | |
---|---|
Current PS Ratio | 43.5x |
Fair PS Ratio | 0.7x |
Price-To-Sales vs Fair Ratio: DNLI is expensive based on its Price-To-Sales Ratio (43.5x) compared to the estimated Fair Price-To-Sales Ratio (0.7x).
Share Price vs Fair Value
What is the Fair Price of DNLI when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.
Below Fair Value: DNLI ($29.3) is trading below our estimate of fair value ($68.77)
Significantly Below Fair Value: DNLI is trading below fair value by more than 20%.
Price to Earnings Growth Ratio
PEG Ratio: Insufficient data to calculate DNLI's PEG Ratio to determine if it is good value.
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Future Growth
How is Denali Therapeutics forecast to perform in the next 1 to 3 years based on estimates from 14 analysts?
Future Growth Score
2/6Future Growth Score 2/6
Earnings vs Savings Rate
Earnings vs Market
High Growth Earnings
Revenue vs Market
High Growth Revenue
Future ROE
29.3%
Forecasted annual earnings growth
Earnings and Revenue Growth Forecasts
Analyst Future Growth Forecasts
Earnings vs Savings Rate: DNLI is forecast to remain unprofitable over the next 3 years.
Earnings vs Market: DNLI is forecast to remain unprofitable over the next 3 years.
High Growth Earnings: DNLI is forecast to remain unprofitable over the next 3 years.
Revenue vs Market: DNLI's revenue (52.5% per year) is forecast to grow faster than the US market (8.3% per year).
High Growth Revenue: DNLI's revenue (52.5% per year) is forecast to grow faster than 20% per year.
Earnings per Share Growth Forecasts
Future Return on Equity
Future ROE: DNLI is forecast to be unprofitable in 3 years.
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Past Performance
How has Denali Therapeutics performed over the past 5 years?
Past Performance Score
0/6Past Performance Score 0/6
Quality Earnings
Growing Profit Margin
Earnings Trend
Accelerating Growth
Earnings vs Industry
High ROE
-5.6%
Historical annual earnings growth
Earnings and Revenue History
Quality Earnings: DNLI is currently unprofitable.
Growing Profit Margin: DNLI is currently unprofitable.
Past Earnings Growth Analysis
Earnings Trend: DNLI is unprofitable, and losses have increased over the past 5 years at a rate of 5.6% per year.
Accelerating Growth: Unable to compare DNLI's earnings growth over the past year to its 5-year average as it is currently unprofitable
Earnings vs Industry: DNLI is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (96.9%).
Return on Equity
High ROE: DNLI has a negative Return on Equity (-31.13%), as it is currently unprofitable.
Discover strong past performing companies
Financial Health
How is Denali Therapeutics's financial position?
Financial Health Score
6/6Financial Health Score 6/6
Short Term Liabilities
Long Term Liabilities
Debt Level
Reducing Debt
Stable Cash Runway
Forecast Cash Runway
Financial Position Analysis
Short Term Liabilities: DNLI's short term assets ($988.4M) exceed its short term liabilities ($341.2M).
Long Term Liabilities: DNLI's short term assets ($988.4M) exceed its long term liabilities ($61.7M).
Debt to Equity History and Analysis
Debt Level: DNLI is debt free.
Reducing Debt: DNLI has not had any debt for past 5 years.
Balance Sheet
Cash Runway Analysis
For companies that have on average been loss making in the past we assess whether they have at least 1 year of cash runway.
Stable Cash Runway: DNLI has sufficient cash runway for more than 3 years based on its current free cash flow.
Forecast Cash Runway: DNLI has sufficient cash runway for more than 3 years if free cash flow continues to grow at historical rates of 24.2% each year
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Dividend
What is Denali Therapeutics's current dividend yield, its reliability and sustainability?
Dividend Score
0/6Dividend Score 0/6
Notable Dividend
High Dividend
Stable Dividend
Growing Dividend
Earnings Coverage
Future Dividend Coverage
Dividend Yield vs Market
Notable Dividend: Unable to evaluate DNLI's dividend yield against the bottom 25% of dividend payers, as the company has not reported any recent payouts.
High Dividend: Unable to evaluate DNLI's dividend yield against the top 25% of dividend payers, as the company has not reported any recent payouts.
Stability and Growth of Payments
Stable Dividend: Insufficient data to determine if DNLI's dividends per share have been stable in the past.
Growing Dividend: Insufficient data to determine if DNLI's dividend payments have been increasing.
Earnings Payout to Shareholders
Earnings Coverage: Insufficient data to calculate payout ratio to determine if its dividend payments are covered by earnings.
Cash Payout to Shareholders
Cash Flow Coverage: Unable to calculate sustainability of dividends as DNLI has not reported any payouts.
Discover strong dividend paying companies
Management
How experienced are the management team and are they aligned to shareholders interests?
3.8yrs
Average management tenure
CEO
Ryan Watts (45 yo)
6.83yrs
Tenure
US$12,673,479
Compensation
Dr. Ryan J. Watts, Ph.D. is the Co-Founder of Denali Therapeutics Inc. and has been its President and Chief Executive Officer since August 2015. Dr. Watts has been a Director of Denali Therapeutics Inc. si...
CEO Compensation Analysis
Compensation vs Market: Ryan's total compensation ($USD12.67M) is above average for companies of similar size in the US market ($USD6.87M).
Compensation vs Earnings: Ryan's compensation has increased whilst the company is unprofitable.
Leadership Team
Experienced Management: DNLI's management team is considered experienced (3.8 years average tenure).
Board Members
Experienced Board: DNLI's board of directors are considered experienced (7.1 years average tenure).
Ownership
Who are the major shareholders and have insiders been buying or selling?
Insider Trading Volume
Insider Buying: Insufficient data to determine if insiders have bought more shares than they have sold in the past 3 months.
Recent Insider Transactions
Ownership Breakdown
Dilution of Shares: Shareholders have not been meaningfully diluted in the past year.
Top Shareholders
Company Information
Denali Therapeutics Inc.'s employee growth, exchange listings and data sources
Key Information
- Name: Denali Therapeutics Inc.
- Ticker: DNLI
- Exchange: NasdaqGS
- Founded: 2013
- Industry: Biotechnology
- Sector: Pharmaceuticals & Biotech
- Implied Market Cap: US$3.602b
- Shares outstanding: 122.95m
- Website: https://www.denalitherapeutics.com
Number of Employees
Location
- Denali Therapeutics Inc.
- 161 Oyster Point Boulevard
- 2nd Floor
- South San Francisco
- California
- 94080
- United States
Listings
Company Analysis and Financial Data Status
Data | Last Updated (UTC time) |
---|---|
Company Analysis | 2022/06/28 00:00 |
End of Day Share Price | 2022/06/28 00:00 |
Earnings | 2022/03/31 |
Annual Earnings | 2021/12/31 |
Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more here.