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Denali Therapeutics NasdaqGS:DNLI Stock Report

Last Price

US$17.14

Market Cap

US$2.4b

7D

11.1%

1Y

-35.4%

Updated

04 May, 2024

Data

Company Financials +

Denali Therapeutics Inc.

NasdaqGS:DNLI Stock Report

Market Cap: US$2.4b

DNLI Stock Overview

Denali Therapeutics Inc., a biopharmaceutical company, develops a portfolio of product candidates engineered to cross the blood-brain barrier for neurodegenerative diseases and lysosomal storage diseases in the United States.

DNLI fundamental analysis
Snowflake Score
Valuation4/6
Future Growth1/6
Past Performance0/6
Financial Health6/6
Dividends0/6

Denali Therapeutics Inc. Competitors

Price History & Performance

Summary of all time highs, changes and price drops for Denali Therapeutics
Historical stock prices
Current Share PriceUS$17.14
52 Week HighUS$33.31
52 Week LowUS$14.56
Beta1.33
1 Month Change-9.74%
3 Month Change6.79%
1 Year Change-35.37%
3 Year Change-68.43%
5 Year Change-23.17%
Change since IPO-20.09%

Recent News & Updates

An Intrinsic Calculation For Denali Therapeutics Inc. (NASDAQ:DNLI) Suggests It's 44% Undervalued

Apr 17
An Intrinsic Calculation For Denali Therapeutics Inc. (NASDAQ:DNLI) Suggests It's 44% Undervalued

Denali Therapeutics Inc.'s (NASDAQ:DNLI) Price Is Right But Growth Is Lacking After Shares Rocket 25%

Mar 21
Denali Therapeutics Inc.'s (NASDAQ:DNLI) Price Is Right But Growth Is Lacking After Shares Rocket 25%

Recent updates

An Intrinsic Calculation For Denali Therapeutics Inc. (NASDAQ:DNLI) Suggests It's 44% Undervalued

Apr 17
An Intrinsic Calculation For Denali Therapeutics Inc. (NASDAQ:DNLI) Suggests It's 44% Undervalued

Denali Therapeutics Inc.'s (NASDAQ:DNLI) Price Is Right But Growth Is Lacking After Shares Rocket 25%

Mar 21
Denali Therapeutics Inc.'s (NASDAQ:DNLI) Price Is Right But Growth Is Lacking After Shares Rocket 25%

Denali: Leveraging Transport Vehicle Technology For Neurological Gains

Mar 07

Companies Like Denali Therapeutics (NASDAQ:DNLI) Are In A Position To Invest In Growth

Feb 21
Companies Like Denali Therapeutics (NASDAQ:DNLI) Are In A Position To Invest In Growth

Improved Revenues Required Before Denali Therapeutics Inc. (NASDAQ:DNLI) Shares Find Their Feet

Jan 26
Improved Revenues Required Before Denali Therapeutics Inc. (NASDAQ:DNLI) Shares Find Their Feet

We're Not Very Worried About Denali Therapeutics' (NASDAQ:DNLI) Cash Burn Rate

Nov 20
We're Not Very Worried About Denali Therapeutics' (NASDAQ:DNLI) Cash Burn Rate

Investor Optimism Abounds Denali Therapeutics Inc. (NASDAQ:DNLI) But Growth Is Lacking

Oct 09
Investor Optimism Abounds Denali Therapeutics Inc. (NASDAQ:DNLI) But Growth Is Lacking

Companies Like Denali Therapeutics (NASDAQ:DNLI) Are In A Position To Invest In Growth

Aug 22
Companies Like Denali Therapeutics (NASDAQ:DNLI) Are In A Position To Invest In Growth

Denali Therapeutics Inc.'s (NASDAQ:DNLI) Intrinsic Value Is Potentially 69% Above Its Share Price

May 02
Denali Therapeutics Inc.'s (NASDAQ:DNLI) Intrinsic Value Is Potentially 69% Above Its Share Price

Analysts Are More Bearish On Denali Therapeutics Inc. (NASDAQ:DNLI) Than They Used To Be

Mar 04
Analysts Are More Bearish On Denali Therapeutics Inc. (NASDAQ:DNLI) Than They Used To Be

Here's Why We're Not Too Worried About Denali Therapeutics' (NASDAQ:DNLI) Cash Burn Situation

Feb 06
Here's Why We're Not Too Worried About Denali Therapeutics' (NASDAQ:DNLI) Cash Burn Situation

These Analysts Think Denali Therapeutics Inc.'s (NASDAQ:DNLI) Sales Are Under Threat

Nov 09
These Analysts Think Denali Therapeutics Inc.'s (NASDAQ:DNLI) Sales Are Under Threat

Denali Therapeutics proposes $250M stock offering; shares down 6% post market

Oct 18

Companies Like Denali Therapeutics (NASDAQ:DNLI) Are In A Position To Invest In Growth

Oct 12
Companies Like Denali Therapeutics (NASDAQ:DNLI) Are In A Position To Invest In Growth

Biogen, Denali begin dosing in late-stage trial of Parkinson's candidate BIIB122

Oct 10

We're Not Very Worried About Denali Therapeutics' (NASDAQ:DNLI) Cash Burn Rate

Jun 08
We're Not Very Worried About Denali Therapeutics' (NASDAQ:DNLI) Cash Burn Rate

Denali Therapeutics Inc. (NASDAQ:DNLI) Analysts Just Slashed This Year's Estimates

Mar 07
Denali Therapeutics Inc. (NASDAQ:DNLI) Analysts Just Slashed This Year's Estimates

Denali Therapeutics: 2021 Was Mostly Bad Luck And Trouble

Feb 25

Are Investors Undervaluing Denali Therapeutics Inc. (NASDAQ:DNLI) By 28%?

Feb 14
Are Investors Undervaluing Denali Therapeutics Inc. (NASDAQ:DNLI) By 28%?

Denali Therapeutics: Another Near-Term Capital Gain Prospect Market-Makers See As Underpriced

Sep 10

Shareholder Returns

DNLIUS BiotechsUS Market
7D11.1%4.7%0.7%
1Y-35.4%2.7%23.9%

Return vs Industry: DNLI underperformed the US Biotechs industry which returned 2.9% over the past year.

Return vs Market: DNLI underperformed the US Market which returned 24.2% over the past year.

Price Volatility

Is DNLI's price volatile compared to industry and market?
DNLI volatility
DNLI Average Weekly Movement13.6%
Biotechs Industry Average Movement11.6%
Market Average Movement6.1%
10% most volatile stocks in US Market16.7%
10% least volatile stocks in US Market3.0%

Stable Share Price: DNLI's share price has been volatile over the past 3 months.

Volatility Over Time: DNLI's weekly volatility (14%) has been stable over the past year, but is still higher than 75% of US stocks.

About the Company

FoundedEmployeesCEOWebsite
2013445Ryan Wattswww.denalitherapeutics.com

Denali Therapeutics Inc., a biopharmaceutical company, develops a portfolio of product candidates engineered to cross the blood-brain barrier for neurodegenerative diseases and lysosomal storage diseases in the United States. The company’s transport vehicle (TV)-enabled programs include DNL310 ETV, an IDS enzyme replacement therapy program for MPS II; TAK-594/DNL593 which is in Phase 1/II for frontotemporal dementia-granulin; DNL126 program for MPS IIIA; and DNL622 for MPS I, as well as other preclinical programs that target amyloid beta and HER2. Its brain-penetrant small molecule programs comprise BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; SAR443820/DNL788 RIPK1 inhibitor program for CNS disease; DNL343 eIF2B Activator program for amyotrophic lateral sclerosis; and SAR443122/DNL758 RIPK1 inhibitor program for peripheral inflammatory diseases.

Denali Therapeutics Inc. Fundamentals Summary

How do Denali Therapeutics's earnings and revenue compare to its market cap?
DNLI fundamental statistics
Market capUS$2.44b
Earnings (TTM)-US$145.22m
Revenue (TTM)US$330.53m

7.4x

P/S Ratio

-16.8x

P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
DNLI income statement (TTM)
RevenueUS$330.53m
Cost of RevenueUS$423.88m
Gross Profit-US$93.34m
Other ExpensesUS$51.88m
Earnings-US$145.22m

Last Reported Earnings

Dec 31, 2023

Next Earnings Date

n/a

Earnings per share (EPS)-1.02
Gross Margin-28.24%
Net Profit Margin-43.94%
Debt/Equity Ratio0%

How did DNLI perform over the long term?

See historical performance and comparison
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