Largest U.S. Pharmaceuticals & Biotech Stocks by Market Cap

Name: Financial Insights Based on S&P Global Market Intelligence
Creator: Simply Wall St Pty Ltd
License: https://www.spglobal.com/content/dam/spglobal/corporate/en/documents/secure/MI-FastTrack-Terms-and-Conditions-July-2023.pdf

UPDATED Dec 23, 2025

Discover large cap U.S. Pharmaceuticals & Biotech companies that are on the NYSE and NASDAQ. These Pharmaceuticals & Biotech Companies are organised by Market Cap.

724 companies

Company	Last Price	7D Return	1Y Return	Market Cap	Analysts Target	Valuation	Growth	Div Yield
LLY Eli Lilly	US$1,071.64	1.6%	34.7%	US$963.9b	US$1,093.22	PE52.1x	E23.0%	0.6%
JNJ Johnson & Johnson	US$205.78	-1.7%	41.1%	US$499.5b	US$209.29	PE19.7x	E1.0%	2.5%
ABBV AbbVie	US$228.79	2.3%	27.1%	US$402.8b	US$244.68	PE172.2x	E32.0%	3.0%
MRK Merck	US$105.04	6.9%	5.6%	US$259.9b	US$110.04	PE13.7x	E9.2%	3.2%
TMO Thermo Fisher Scientific	US$579.94	1.7%	9.6%	US$216.3b	US$639.39	PE33.2x	E10.5%	0.3%
AMGN Amgen	US$331.49	1.5%	25.3%	US$178.4b	US$325.88	PE25.5x	E9.5%	3.0%
DHR Danaher	US$230.83	2.7%	0.03%	US$161.1b	US$258.09	PE46.5x	E17.1%	0.6%
GILD Gilead Sciences	US$125.19	5.4%	33.3%	US$154.0b	US$132.38	PE19.2x	E7.4%	2.5%
PFE Pfizer	US$24.88	-2.5%	-7.0%	US$143.3b	US$28.62	PE14.4x	E1.1%	6.9%
VRTX Vertex Pharmaceuticals	US$459.21	0.9%	12.5%	US$116.8b	US$489.04	PE31.7x	E13.6%	n/a
BMY Bristol-Myers Squibb	US$54.28	0.09%	-6.0%	US$111.3b	US$54.50	PE18.3x	E3.6%	4.6%
REGN Regeneron Pharmaceuticals	US$785.17	5.2%	9.9%	US$80.0b	US$789.90	PE17.6x	E8.5%	0.4%
ZTS Zoetis	US$123.54	0.3%	-25.0%	US$54.5b	US$158.22	PE20.5x	E6.5%	1.7%
ALNY Alnylam Pharmaceuticals	US$398.70	1.9%	63.9%	US$53.9b	US$491.92	PE1209.1x	E50.7%	n/a
A Agilent Technologies	US$138.36	-0.6%	1.7%	US$39.3b	US$168.29	PE30.1x	E9.7%	0.7%
IQV IQVIA Holdings	US$225.15	1.6%	12.6%	US$38.2b	US$253.95	PE29.9x	E13.9%	n/a
INSM Insmed	US$176.77	-11.9%	150.6%	US$37.5b	US$214.94	PS84.3x	E71.1%	n/a
TEVA Teva Pharmaceutical Industries	US$31.54	4.8%	40.7%	US$35.8b	US$32.77	PE50.8x	E21.9%	0%
ONC BeOne Medicines	US$312.32	2.6%	72.0%	US$34.7b	US$400.06	PE504.2x	E46.6%	n/a
NTRA Natera	US$235.40	3.5%	45.0%	US$32.6b	US$246.26	PS15.4x	E59.6%	n/a
MTD Mettler-Toledo International	US$1,412.41	-0.004%	14.4%	US$28.7b	US$1,503.38	PE34.5x	E7.4%	n/a
BIIB Biogen	US$174.82	1.9%	17.3%	US$25.6b	US$180.69	PE15.9x	E7.7%	n/a
WAT Waters	US$383.21	1.2%	2.7%	US$22.9b	US$406.34	PE35.2x	E14.3%	n/a
RPRX Royalty Pharma	US$39.39	2.6%	56.1%	US$22.4b	US$46.32	PE22x	E10.4%	2.2%

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