Largest U.S. Pharmaceuticals & Biotech Stocks by Market Cap

Name: Financial Insights Based on S&P Global Market Intelligence
Creator: Simply Wall St Pty Ltd
License: https://www.spglobal.com/content/dam/spglobal/corporate/en/documents/secure/MI-FastTrack-Terms-and-Conditions-July-2023.pdf

UPDATED Nov 16, 2025

Discover large cap U.S. Pharmaceuticals & Biotech companies that are on the NYSE and NASDAQ. These Pharmaceuticals & Biotech Companies are organised by Market Cap.

731 companies

Company	Last Price	7D Return	1Y Return	Market Cap	Analysts Target	Valuation	Growth	Div Yield
LLY Eli Lilly	US$1,025.28	10.9%	37.4%	US$918.0b	US$1,003.15	PE49.9x	E20.4%	0.6%
JNJ Johnson & Johnson	US$195.93	5.0%	27.2%	US$472.1b	US$200.82	PE18.8x	E0.2%	2.7%
ABBV AbbVie	US$232.36	6.0%	40.8%	US$410.7b	US$243.55	PE174.9x	E32.2%	3.0%
MRK Merck	US$92.92	7.7%	-3.5%	US$230.6b	US$102.32	PE12.1x	E4.4%	3.5%
TMO Thermo Fisher Scientific	US$578.71	1.1%	12.8%	US$217.4b	US$613.58	PE33.1x	E10.2%	0.3%
AMGN Amgen	US$336.74	5.2%	18.7%	US$181.3b	US$318.51	PE25.9x	E9.5%	2.8%
DHR Danaher	US$221.21	5.4%	-4.0%	US$156.3b	US$254.20	PE44.6x	E17.2%	0.6%
GILD Gilead Sciences	US$125.02	5.2%	41.4%	US$155.1b	US$130.61	PE19.1x	E8.5%	2.5%
PFE Pfizer	US$25.06	2.6%	1.0%	US$142.5b	US$28.96	PE14.5x	E1.7%	6.9%
VRTX Vertex Pharmaceuticals	US$437.15	6.8%	-6.1%	US$110.9b	US$484.08	PE30.2x	E13.6%	n/a
BMY Bristol-Myers Squibb	US$46.65	-0.09%	-17.0%	US$95.0b	US$52.73	PE15.7x	E4.3%	5.3%
REGN Regeneron Pharmaceuticals	US$693.50	5.5%	-8.4%	US$71.2b	US$749.21	PE15.5x	E6.6%	0.5%
ALNY Alnylam Pharmaceuticals	US$449.16	1.5%	90.7%	US$59.3b	US$483.40	PE1362.1x	E51.2%	n/a
ZTS Zoetis	US$120.82	0.5%	-31.0%	US$53.2b	US$170.63	PE20.1x	E6.2%	1.7%
A Agilent Technologies	US$146.82	0.05%	15.5%	US$41.6b	US$152.33	PE34.1x	E11.7%	0.7%
INSM Insmed	US$193.22	1.9%	191.5%	US$41.2b	US$208.56	PS92.2x	E72.2%	n/a
ONC BeOne Medicines	US$365.82	14.3%	93.3%	US$40.5b	US$395.37	PE590.5x	E46.7%	n/a
IQV IQVIA Holdings	US$220.61	4.8%	14.5%	US$37.6b	US$247.50	PE29.3x	E13.9%	n/a
TEVA Teva Pharmaceutical Industries	US$25.41	6.0%	54.7%	US$29.2b	US$27.68	PE40.9x	E17.4%	0%
MTD Mettler-Toledo International	US$1,403.08	-2.5%	18.9%	US$28.7b	US$1,492.64	PE34.3x	E7.4%	n/a
NTRA Natera	US$204.28	2.4%	39.9%	US$28.2b	US$230.89	PS13.3x	E64.9%	n/a
BNTX BioNTech	US$103.09	-0.05%	3.4%	US$24.8b	US$135.86	PS6.8x	E7.4%	n/a
BIIB Biogen	US$167.55	7.7%	4.7%	US$24.6b	US$176.10	PE15.3x	E6.3%	n/a
RPRX Royalty Pharma	US$39.16	1.6%	52.4%	US$22.6b	US$45.54	PE21.9x	E10.4%	2.2%

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