Denali Therapeutics Inc.

NasdaqGS:DNLI Stock Report

Market Cap: US$3.6b

Denali Therapeutics Valuation

Is DNLI undervalued compared to its fair value, analyst forecasts and its price relative to the market?

Valuation Score

1/6

Valuation Score 1/6

  • Below Fair Value

  • Significantly Below Fair Value

  • Price-To-Book vs Peers

  • Price-To-Book vs Industry

  • Price-To-Book vs Fair Ratio

  • Analyst Forecast

Share Price vs Fair Value

What is the Fair Price of DNLI when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.

Below Fair Value: Insufficient data to calculate DNLI's fair value for valuation analysis.

Significantly Below Fair Value: Insufficient data to calculate DNLI's fair value for valuation analysis.


Key Valuation Metric

Which metric is best to use when looking at relative valuation for DNLI?

Key metric: As DNLI is unprofitable and pre-revenue we use its Price-To-Book Ratio for relative valuation analysis.

The above table shows the Price to Book ratio for DNLI. This is calculated by dividing DNLI's market cap by their current book value.
What is DNLI's PB Ratio?
PB Ratio2.7x
BookUS$1.32b
Market CapUS$3.60b

Price to Book Ratio vs Peers

How does DNLI's PB Ratio compare to its peers?

The above table shows the PB ratio for DNLI vs its peers. Here we also display the market cap and forecasted growth for additional consideration.
CompanyForward PBEstimated GrowthMarket Cap
Peer Average467.5x
MLTX MoonLake Immunotherapeutics
7x-0.09%US$3.4b
RYZB RayzeBio
6.5x2.0%US$3.7b
IMVT Immunovant
9.2x8.3%US$4.1b
VSBC VitaSpring Biomedical
1847xn/aUS$3.1b
DNLI Denali Therapeutics
2.7x25.6%US$3.6b

Price-To-Book vs Peers: DNLI is good value based on its Price-To-Book Ratio (2.7x) compared to the peer average (7.6x).


Price to Book Ratio vs Industry

How does DNLI's PB Ratio compare vs other companies in the US Biotechs Industry?

58 CompaniesPrice / BookEstimated GrowthMarket Cap
GRAL GRAIL
0.2x35.7%US$588.01m
AMRN Amarin
0.4x-7.7%US$208.43m
IMAB I-Mab
0.4x1.8%US$77.50m
MGX Metagenomi
0.3x-23.2%US$77.47m
DNLI 2.7xIndustry Avg. 2.0xNo. of Companies71PB01.63.24.86.48+
58 CompaniesEstimated GrowthMarket Cap
No more companies

Price-To-Book vs Industry: DNLI is expensive based on its Price-To-Book Ratio (2.7x) compared to the US Biotechs industry average (1.9x).


Price to Book Ratio vs Fair Ratio

What is DNLI's PB Ratio compared to its Fair PB Ratio? This is the expected PB Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.

DNLI PB Ratio vs Fair Ratio.
Fair Ratio
Current PB Ratio2.7x
Fair PB Ration/a

Price-To-Book vs Fair Ratio: Insufficient data to calculate DNLI's Price-To-Book Fair Ratio for valuation analysis.


Analyst Price Targets

What is the analyst 12-month forecast and do we have any statistical confidence in the consensus price target?

The above table shows the analyst DNLI forecast and predictions for the stock price in 12 month’s time.
DateShare PriceAverage 1Y Price TargetDispersionHighLow1Y Actual priceAnalysts
CurrentUS$25.00
US$42.08
+68.3%
36.1%US$90.00US$28.00n/a13
Nov ’25US$27.05
US$41.15
+52.1%
39.5%US$90.00US$22.00n/a13
Oct ’25US$28.67
US$39.21
+36.8%
40.5%US$90.00US$22.00n/a14
Sep ’25US$24.44
US$38.86
+59.0%
41.5%US$90.00US$22.00n/a14
Aug ’25US$23.33
US$38.47
+64.9%
44.3%US$95.00US$22.00n/a15
Jul ’25US$22.01
US$38.67
+75.7%
43.7%US$95.00US$22.00n/a15
Jun ’25US$18.56
US$38.67
+108.3%
43.7%US$95.00US$22.00n/a15
May ’25US$16.16
US$40.27
+149.2%
43.1%US$95.00US$24.00n/a15
Apr ’25US$20.56
US$42.80
+108.2%
43.7%US$95.00US$24.00n/a15
Mar ’25US$20.86
US$43.13
+106.8%
42.7%US$95.00US$26.00n/a15
Feb ’25US$16.39
US$46.67
+184.7%
45.3%US$105.00US$26.00n/a15
Jan ’25US$21.46
US$46.67
+117.5%
45.3%US$105.00US$26.00n/a15
Dec ’24US$18.97
US$50.31
+165.2%
40.5%US$105.00US$26.00n/a16
Nov ’24US$19.03
US$52.27
+174.7%
37.7%US$105.00US$26.00US$27.0515
Oct ’24US$20.63
US$55.60
+169.5%
37.3%US$105.00US$26.00US$28.6715
Sep ’24US$23.31
US$56.86
+143.9%
36.7%US$105.00US$26.00US$24.4414
Aug ’24US$28.32
US$58.93
+108.1%
34.7%US$105.00US$30.00US$23.3314
Jul ’24US$29.51
US$58.93
+99.7%
34.7%US$105.00US$30.00US$22.0114
Jun ’24US$30.92
US$58.93
+90.6%
33.9%US$105.00US$30.00US$18.5615
May ’24US$25.80
US$59.67
+131.3%
34.0%US$105.00US$32.00US$16.1615
Apr ’24US$23.04
US$59.69
+159.1%
32.9%US$105.00US$32.00US$20.5616
Mar ’24US$27.30
US$60.94
+123.2%
33.0%US$105.00US$36.00US$20.8616
Feb ’24US$30.88
US$63.75
+106.4%
31.1%US$105.00US$36.00US$16.3916
Jan ’24US$27.81
US$64.33
+131.3%
31.3%US$105.00US$36.00US$21.4615
Dec ’23US$31.20
US$64.80
+107.7%
30.5%US$105.00US$38.00US$18.9715
Nov ’23US$28.96
US$66.43
+129.4%
30.0%US$105.00US$38.00US$19.0314

Analyst Forecast: Target price is more than 20% higher than the current share price, but analysts are not within a statistically confident range of agreement.


Discover undervalued companies