U.S. Pharmaceuticals & Biotech Leverage Leaders

Vaxcyte

Market Cap: US$8.9b

A clinical-stage vaccine innovation company, develops conjugate and novel protein vaccines to prevent or treat bacterial infectious diseases.

Dianthus Therapeutics

Market Cap: US$4.9b

A clinical-stage biotechnology company, engages in the development of therapies for patients with severe autoimmune diseases.

Stevanato Group

Market Cap: US$3.8b

Engages in the design, production, and distribution of products and processes to provide solutions for biopharma and healthcare industries in Europe, the Middle East, Africa, North America, South America, and the Asia Pacific.

Biogen

Market Cap: US$26.0b

Biogen Inc. discovers, develops, manufactures, and delivers therapies in the United States, Europe, Germany, Asia, and internationally.

Qiagen

Market Cap: US$8.5b

Provides sample to insight solutions that transform biological samples into molecular insights worldwide.

ACADIA Pharmaceuticals

Market Cap: US$3.8b

A biopharmaceutical company, focuses on the development and commercialization of medicines for neurological and rare disease in North America.

Centessa Pharmaceuticals

Market Cap: US$6.1b

Centessa Pharmaceuticals plc, together with its subsidiaries, discovers, develops, and delivers orexin-based neuroscience therapeutics in the United Kingdom and the United States.

Exelixis

Market Cap: US$11.8b

An oncology company, focuses on the discovery, development, and commercialization of new medicines for difficult-to-treat cancers in the United States.

Corcept Therapeutics

Market Cap: US$4.5b

A biopharmaceutical company, engages in the discovery and development of medications to treat severe endocrinologic, oncologic, metabolic, and neurologic disorders in the United States.

ADMA Biologics

Market Cap: US$2.3b

A biopharmaceutical company, develops, manufactures, and markets specialty plasma-derived biologics for the treatment of immune deficiencies and infectious diseases in the United States and internationally.

IDEAYA Biosciences

Market Cap: US$2.7b

A precision medicine oncology company, discovers and develops targeted therapeutics for patient populations selected using molecular diagnostics in the United States.

United Therapeutics

Market Cap: US$25.2b

Engages in the development and commercialization of products to address the unmet medical needs of patients with chronic and life-threatening diseases in the United States and internationally.

Structure Therapeutics

Market Cap: US$3.9b

A clinical stage global biopharmaceutical company, develops and delivers novel oral small molecule therapeutics to treat various chronic diseases with unmet medical needs in the United States.

Beam Therapeutics

Market Cap: US$2.6b

A biotechnology company, engages in the development of precision genetic medicines for patients suffering from serious diseases in the United States.

Kiniksa Pharmaceuticals International

Market Cap: US$3.6b

A biopharmaceutical company, develops and commercializes medical therapies in the United States, the United Kingdom, and internationally.

Regeneron Pharmaceuticals

Market Cap: US$78.8b

Regeneron Pharmaceuticals, Inc. discovers, invents, develops, manufactures, and commercializes medicines to treat various diseases worldwide.

Catalyst Pharmaceuticals

Market Cap: US$3.1b

A commercial-stage biopharmaceutical company, focuses on developing and commercializing medicines for patients living with rare diseases in the United States.

Terns Pharmaceuticals

Market Cap: US$6.1b

A clinical-stage biopharmaceutical company, develops small-molecule product candidates for the treatment of oncology and obesity.

Supernus Pharmaceuticals

Market Cap: US$3.0b

A biopharmaceutical company, engages in the development and commercialization of products for the treatment of central nervous system (CNS) diseases in the United States.

Erasca

Market Cap: US$5.4b

A clinical-stage precision oncology company, focuses on discovering, developing, and commercializing therapies for patients with RAS/MAPK pathway-driven cancers.

Xenon Pharmaceuticals

Market Cap: US$5.6b

A neuroscience-focused biopharmaceutical company, engages in the discovery, development, and delivery of therapeutics to treat patients with neurological and psychiatric disorders.

Apogee Therapeutics

Market Cap: US$6.4b

A clinical stage biotechnology company, develops novel biologics for the treatment of atopic dermatitis, asthma, eosinophilic esophagitis, chronic obstructive pulmonary disease, and other inflammatory and immunology indications in the United States.

Stoke Therapeutics

Market Cap: US$2.1b

Engages in the development of treatments for severe genetic diseases by upregulating protein expression.

Enliven Therapeutics

Market Cap: US$2.7b

A clinical-stage biopharmaceutical company, focuses on the discovery and development of small molecule inhibitors to help patients with cancer.

Incyte

Market Cap: US$19.3b

A biopharmaceutical company, engages in the discovery, development, and commercialization of therapeutics in the United States, Europe, Canada, and Japan.

Bio-Techne

Market Cap: US$8.7b

Develops, manufactures, and sells life science reagents, instruments, and services for the research, diagnostics, and bioprocessing markets worldwide.

Agilent Technologies

Market Cap: US$32.6b

Provides application focused solutions to the life sciences, diagnostics, and applied chemical markets worldwide.

Spyre Therapeutics

Market Cap: US$4.1b

A clinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD) and rheumatic diseases.

Neurocrine Biosciences

Market Cap: US$13.2b

Neurocrine Biosciences, Inc. discovers, develops, and commercialize pharmaceuticals for neurological, psychiatric, endocrine, and immunological disorders in the United States and internationally.

Tango Therapeutics

Market Cap: US$3.0b

A precision oncology company, focuses on the discovery and development of drugs in defined patient populations with unmet medical need.

Denali Therapeutics

Market Cap: US$3.1b

A biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases.

Celldex Therapeutics

Market Cap: US$2.6b

A biopharmaceutical company, engages in developing therapeutic antibodies for patients with severe inflammatory, allergic, autoimmune, and other diseases.

Roivant Sciences

Market Cap: US$20.4b

A clinical-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of medicines and technologies.

Oruka Therapeutics

Market Cap: US$3.2b

A clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psoriasis (PsO), and other inflammatory and immunology (I&I) indications.

Immunome

Market Cap: US$2.5b

A biotechnology company, engages in the discovery, design, development, manufacturing, and commercialization of antibody-drug conjugates and other oncology therapeutics in the United States.

Viking Therapeutics

Market Cap: US$4.1b

A clinical-stage biopharmaceutical company, focuses on the development of novel therapies for metabolic and endocrine disorders.