Immunome (IMNM) Stock Overview

A biotechnology company, engages in the discovery, design, development, manufacturing, and commercialization of antibody-drug conjugates and other oncology therapeutics in the United States. More details

IMNM fundamental analysis
Snowflake Score
Valuation	4/6
Future Growth	2/6
Past Performance	0/6
Financial Health	6/6
Dividends	0/6

Rewards

Trading at 87.3% below our estimate of its fair value

Revenue is forecast to grow 53.38% per year

Analysts in good agreement that stock price will rise by 54.5%

Risk Analysis

Shareholders have been substantially diluted in the past year

Currently unprofitable and not forecast to become profitable over the next 3 years

Significant insider selling over the past 3 months

IMNM Community Fair Values

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Immunome, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Immunome
Historical stock prices
Current Share Price	US$23.00
52 Week High	US$27.65
52 Week Low	US$7.42
Beta	2.12
1 Month Change	6.14%
3 Month Change	-7.74%
1 Year Change	189.67%
3 Year Change	269.77%
5 Year Change	29.65%
Change since IPO	71.00%

Recent updates

Seeking Alpha • Jan 30

Immunome Can Take The Fight To Competitors With Varegacestat

Summary Immunome's varegacestat is in a phase 3 trial in patients with desmoid tumors that should produce results in H2'25. Varegacestat offers potential advantages, such as once-daily dosing, over SWTX's already-marketed drug for desmoid tumors, Ogsiveo. IMNM's announcement of a plan to offer $125M of common stock could provide a dip in the stock, but would provide more funds to develop its pipeline of antibody-drug conjugates. Read the full article on Seeking Alpha

Seeking Alpha • Dec 11

Immunome: A Recently Acquired Lead Asset And A Small Market

Summary Immunome's lead asset, AL102, is in a Phase 3 trial for desmoid tumors, showing promising ORR compared to the approved OGSIVEO. Immunome has a turbulent history, shifting focus from COVID-19 therapies to oncology, and acquiring AL102 from Ayala Therapeutics. Financially, Immunome has a market cap of $867mn and a cash runway of 4-5 quarters, risking dilution before drug launch. Despite the potential, IMNM's current market cap already reflects the risk-adjusted value of AL102, making it an avoid for now. Read the full article on Seeking Alpha

Seeking Alpha • Jan 18

Immunome: Why It Has Doubled Over The Last Month

Summary Immunome has experienced a meteoric rise in market capitalization without any pipeline drugs reaching clinical trials. The company's pipeline includes IM-1021, an antibody-drug conjugate targeting ROR1, and IM-4320, a monoclonal antibody targeting IL-38. IMNM's financial overview shows a cash runway of approximately 5 years, but the long wait time for clinical trials poses a significant risk. Read the full article on Seeking Alpha

Analysis Article • Mar 17

Will Immunome (NASDAQ:IMNM) Spend Its Cash Wisely?

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...

Analysis Article • Nov 20

Is Immunome (NASDAQ:IMNM) In A Good Position To Deliver On Growth Plans?

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...

Seeking Alpha • Aug 05

Immunome GAAP EPS of -$0.74

Immunome press release (NASDAQ:IMNM): Q2 GAAP EPS of -$0.74. As of June 30, 2022, cash and cash equivalents totaled $34.6 million.

Analysis Article • Aug 05

Here's Why We're Watching Immunome's (NASDAQ:IMNM) Cash Burn Situation

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although...

Seeking Alpha • Jun 30

Immunome gains 34% after preclinical data on COVID-19 antibody

Clinical-stage biotech Immunome (NASDAQ:IMNM) added ~34% on Thursday on the publication of research indicating that the company’s experimental three-antibody cocktail IMM-BCP-01 was effective against COVID-19 variants of concern including BA.1 and BA.2. IMM-BCP-01 consists of three patient-derived neutralizing antibodies, designed to target non-overlapping regions on the SARS-CoV-2 spike protein. According to results published in the journal science, IMM-BCP-01 was found to have decreased Omicron infection in the lungs of Syrian golden hamsters. The lab results have also indicated potential antiviral effector response, including phagocytosis, antibody-mediated cellular cytotoxicity, complement pathway activation. Results indicate that “IMM-BCP-01 could be a promising means for preventing or treating infection of SARS-CoV-2 variants of concern, including Omicron BA.1 and BA.2, in susceptible individuals,” researchers wrote. Early this month, Immunome (IMNM) announced the dosing initiation of an early-stage study for IMM-BCP-01 involving recently diagnosed COVID-19 patients. The topline data from the single dose, dose escalation study is expected in 2H 2022.

Analysis Article • Feb 21

We Think Immunome (NASDAQ:IMNM) Can Afford To Drive Business Growth

Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...

Analysis Article • Oct 02

Companies Like Immunome (NASDAQ:IMNM) Are In A Position To Invest In Growth

We can readily understand why investors are attracted to unprofitable companies. For example, biotech and mining...

Shareholder Returns

	IMNM	US Biotechs	US Market
7D	-1.4%	0.1%	2.6%
1Y	189.7%	35.5%	26.2%

Return vs Industry: IMNM exceeded the US Biotechs industry which returned 42% over the past year.

Return vs Market: IMNM exceeded the US Market which returned 31.1% over the past year.

Price Volatility

Is IMNM's price volatile compared to industry and market?
IMNM volatility
IMNM Average Weekly Movement	6.9%
Biotechs Industry Average Movement	10.7%
Market Average Movement	7.2%
10% most volatile stocks in US Market	16.1%
10% least volatile stocks in US Market	3.2%

Stable Share Price: IMNM has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: IMNM's weekly volatility (7%) has been stable over the past year.

About the Company

Founded	Employees	CEO	Website
2006	177	Clay Siegall	immunome.com

Immunome, Inc., a biotechnology company, engages in the discovery, design, development, manufacturing, and commercialization of antibody-drug conjugates and other oncology therapeutics in the United States. The company develops clinical asset comprising Varegacestat, a gamma secretase inhibitor that is in Phase 3 clinical trial for the treatment of desmoid tumors; and IM-1021, a receptor tyrosine kinase-like orphan receptor 1 antibody-drug conjugate (ADC), which is in Phase 1 clinical trial. It is also developing preclinical assets, including IM-3050, a fibroblast activation protein targeted radioligand therapy; and solid tumor ADC drug candidates, such as IM-1617, IM-1340, and IM-1335.

Immunome, Inc. Fundamentals Summary

How do Immunome's earnings and revenue compare to its market cap?
IMNM fundamental statistics
Market cap	US$2.54b
Earnings (TTM)	-US$212.39m
Revenue (TTM)	US$6.94m

375.3x

P/S Ratio

-12.3x

P/E Ratio

Is IMNM overvalued?

See Fair Value and valuation analysis

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
IMNM income statement (TTM)
Revenue	US$6.94m
Cost of Revenue	US$177.29m
Gross Profit	-US$170.34m
Other Expenses	US$42.05m
Earnings	-US$212.39m

Last Reported Earnings

Dec 31, 2025

Next Earnings Date

n/a

Earnings per share (EPS)	-1.88
Gross Margin	-2,454.19%
Net Profit Margin	-3,059.99%
Debt/Equity Ratio	0%

How did IMNM perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

Data	Last Updated (UTC time)
Company Analysis	2026/05/11 16:49
End of Day Share Price	2026/05/11 00:00
Earnings	2025/12/31
Annual Earnings	2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

Package	Data	Timeframe	Example US Source ^*
Company Financials	10 years	Income statement Cash flow statement Balance sheet	SEC Form 10-K SEC Form 10-Q
Analyst Consensus Estimates	+3 years	Forecast financials Analyst price targets	Analyst Research Reports Blue Matrix
Market Prices	30 years	Stock prices Dividends, Splits and Actions	ICE Market Data SEC Form S-1
Ownership	10 years	Top shareholders Insider trading	SEC Form 4 SEC Form 13D
Management	10 years	Leadership team Board of directors	SEC Form 10-K SEC Form DEF 14A
Key Developments	10 years	Company announcements	SEC Form 8-K

^* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Immunome, Inc. is covered by 14 analysts. 13 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

Analyst	Institution
Adam Vogel	Craig-Hallum Capital Group LLC
Cory Kasimov	Evercore ISI
Salveen Richter	Goldman Sachs

Immunome (IMNM) Stock Overview

Rewards

Risk Analysis

Immunome, Inc. Competitors

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Price History & Performance

Recent News & Updates

Immunome Files NDA for Varegacestat After Phase 3 Success in Desmoid Tumors

Immunome Inc Submits New Drug Application for Varegacestat for Treatment of Adults with Desmoid Tumors

Immunome, Inc., Annual General Meeting, Jun 09, 2026

Director recently sold US$1.3m worth of stock

Director notifies of intention to sell stock

Consensus revenue estimates decrease by 44%, EPS upgraded

Recent updates

Immunome Files NDA for Varegacestat After Phase 3 Success in Desmoid Tumors

Immunome Inc Submits New Drug Application for Varegacestat for Treatment of Adults with Desmoid Tumors

Immunome, Inc., Annual General Meeting, Jun 09, 2026

Director recently sold US$1.3m worth of stock

Director notifies of intention to sell stock

Consensus revenue estimates decrease by 44%, EPS upgraded

Full year 2025 earnings: EPS and revenues miss analyst expectations

Immunome, Inc. has completed a Follow-on Equity Offering in the amount of $400.4375 million.

Immunome, Inc. has filed a Follow-on Equity Offering in the amount of $400 million.

Price target increased by 25% to US$30.00

Third quarter 2025 earnings released: US$0.65 loss per share (vs US$0.78 loss in 3Q 2024)

New minor risk - Share price stability

Second quarter 2025 earnings: EPS and revenues exceed analyst expectations

Consensus revenue estimates increase by 118%

Price target decreased by 9.7% to US$24.50

First quarter 2025 earnings: EPS and revenues exceed analyst expectations

Immunome, Inc., Annual General Meeting, Jun 10, 2025

New minor risk - Share price stability

Consensus revenue estimates decrease by 41%, EPS upgraded

Chief Technical Officer recently bought US$104k worth of stock

Full year 2024 earnings: EPS and revenues miss analyst expectations

Price target decreased by 12% to US$27.00

Immunome, Inc. Doses First Patient in Phase 1 Trial of IM-1021, A ROR1-Targeted ADC

Immunome, Inc. has completed a Follow-on Equity Offering in the amount of $150.000002 million.

Immunome Can Take The Fight To Competitors With Varegacestat

Immunome, Inc. has filed a Follow-on Equity Offering in the amount of $125 million.

New major risk - Shareholder dilution

Immunome: A Recently Acquired Lead Asset And A Small Market

New minor risk - Share price stability

President recently bought US$962k worth of stock

Third quarter 2024 earnings: Revenues exceed analysts expectations while EPS lags behind

Immunome Presents Preclinical Data Demonstrating Robust Anti-Tumor Activity for IM-1021

Immunome, Inc. Appoints Roee Shahar as Executive Vice President, Commercial

Executive VP of Operations notifies of intention to sell stock

Immunome, Inc. to Present Updated Results for RINGSIDE Phase 2 Trial of AL102 for the Treatment of Desmoid Tumors At the European Society for Medical Oncology Congress 2024

Consensus revenue estimates increase by 21%, EPS downgraded

Price target decreased by 8.7% to US$30.60

Immunome, Inc. Appoints Phil Tsai as Chief Technical Officer

President recently bought US$1.4m worth of stock

Consensus EPS estimates fall by 97%, revenue upgraded

Immunome, Inc. (NasdaqCM:IMNM) completed the acquisition of Substantially all Assets of Atreca, Inc. (NasdaqGS:BCEL).

Immunome, Inc. Announces Promotion of Max Rosett to Chief Financial Officer

Immunome, Inc. has filed a Follow-on Equity Offering in the amount of $200 million.

Immunome, Inc. Appoints Kinney Horn as Chief Business Officer

Immunome, Inc., Annual General Meeting, Jun 12, 2024

Immunome, Inc. Appoints Sandra M. Swain to Board of Directors

Consensus EPS estimates fall by 17%

Immunome, Inc. (NasdaqCM:IMNM) completed the acquisition of Assets from Ayala Pharmaceuticals, Inc. (OTCPK:ADXS).

Immunome, Inc. has completed a Follow-on Equity Offering in the amount of $200 million.

Immunome, Inc. has filed a Follow-on Equity Offering in the amount of $200 million.

New minor risk - Share price stability

Immunome, Inc. Announces Promotion of Max Rosett to Executive Vice President, Operations

Consensus EPS estimates upgraded to US$0.97 loss

Immunome: Why It Has Doubled Over The Last Month

Immunome Appoints Phil Roberts as Chief Technical Officer

Immunome, Inc. Announces Board Changes

Immunome, Inc. Announces Executive Changes, Effective January 2, 2024

Immunome, Inc. announced that it has received $124.722508 million in funding from Enavate Sciences, EcoR1 Capital, LLC, Redmile Group, LLC, Janus Henderson Group plc, Avidity Partners Management, L.P., Woodline Partners LP and other investors

Immunome, Inc. Appoints Jean-Jacques Bienaimé to Board of Directors

Immunome Appoints Bob Lechleider as Chief Medical Officer

Less than half of directors are independent

New major risk - Shareholder dilution

Immunome, Inc. (NasdaqCM:IMNM) entered into an agreement to acquire MorphImmune, Inc. from Research Bridge Partners, Investment Arm and others for $51.7 million.