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Edgewise Therapeutics, Inc.NasdaqGS:EWTX Stock Report

Market Cap US$3.5b
Share Price
US$33.56
US$43.67
23.1% undervalued intrinsic discount
1Y134.3%
7D6.8%
1D
Portfolio Value
​
View

Edgewise Therapeutics, Inc.

NasdaqGS:EWTX Stock Report

Market Cap: US$3.5b

Edgewise Therapeutics (EWTX) Stock Overview

A biopharmaceutical company, discovers, develops, and commercializes therapies for the treatment of muscle disorders. More details

EWTX fundamental analysis
Snowflake Score
Valuation0/6
Future Growth2/6
Past Performance0/6
Financial Health6/6
Dividends0/6

Rewards

Revenue is forecast to grow 66.25% per year

Risk Analysis

Makes less than USD$1m in revenue ($0)

Currently unprofitable and not forecast to become profitable over the next 3 years

Significant insider selling over the past 3 months


EWTX Community Fair Values

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Edgewise Therapeutics, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Edgewise Therapeutics
Historical stock prices
Current Share PriceUS$33.56
52 Week HighUS$39.96
52 Week LowUS$12.15
Beta0.25
1 Month Change6.27%
3 Month Change11.42%
1 Year Change134.28%
3 Year Change244.21%
5 Year Change17.42%
Change since IPO11.87%

Recent News & Updates

Recent updates

Seeking Alpha • Dec 29

Edgewise: Maintaining Buy On Part D EDG-7500 Data And Next Q2 2026 Catalyst

Summary Edgewise Therapeutics, Inc. maintains a Buy rating, driven by favorable interim 12-week safety data for EDG-7500 in phase 2 CIRRUS-HCM and multiple 2026 catalysts. EDG-7500 demonstrated strong tolerability and no clinically meaningful LVEF reductions, potentially differentiating it from cardiac myosin inhibitors for HCM treatment. Key 2026 catalysts include phase 2 CIRRUS-HCM efficacy data in Q2 2026 and potential phase 3 initiation for EDG-7500 in Q4 2026, targeting both oHCM and nHCM patients. EWTX is also advancing Sevasemten for BMD and DMD, with pivotal data and regulatory milestones expected in late 2026, supported by recent capital raises. Read the full article on Seeking Alpha
Analysis Article • Mar 12

Here's Why We're Not At All Concerned With Edgewise Therapeutics' (NASDAQ:EWTX) Cash Burn Situation

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Seeking Alpha • Mar 10

Edgewise Therapeutics: More Expensive Now, But Much More Derisked

Summary Edgewise Therapeutics' stock surged after strong midstage data from its Becker Muscular Dystrophy program, with the lead molecule sevasemten showing promising results. The GRAND CANYON trial, targeting Becker Muscular Dystrophy, aims for regulatory approval with primary endpoint NSAA, following positive Phase 2 CANYON data. Financially, Edgewise has a market cap of $2.67bn and a cash runway of 8-9 quarters, supporting ongoing and future trials. Despite the increased stock price, EWTX remains a buy due to its derisked status and potential success across multiple myosin inhibition programs. Read the full article on Seeking Alpha
Seeking Alpha • Dec 31

Edgewise: Remains A Buy After Latest Becker Muscular Dystrophy Data

Summary Company achieved positive phase 2 CANYON study results for sevasemten in Becker Muscular Dystrophy, boosting long-term investment potential. Key catalysts include FDA and EMA meetings, GRAND CANYON study recruitment completion, and phase 2 CANYON data publication, all expected to likely enhance shareholder value. The pipeline extends beyond BMD, with sevasemten in phase 2 trials for Duchenne Muscular Dystrophy and EDG-7500 targeting Hypertrophic Cardiomyopathy, offering multiple growth opportunities. The global Becker Muscular Dystrophy market is expected to reach $1.28 billion by 2034. Read the full article on Seeking Alpha
Analysis Article • Nov 26

Here's Why We're Not Too Worried About Edgewise Therapeutics' (NASDAQ:EWTX) Cash Burn Situation

We can readily understand why investors are attracted to unprofitable companies. By way of example, Edgewise...
Seeking Alpha • Sep 19

Edgewise: Stock Is Bouncing On Heart Disease Drug Data, Albeit From Just 7 Patients (Rating Upgrade)

Summary I previously rated Edgewise Therapeutics a sell due to limited market potential and lack of clinical data for sevasemten. Sevasemten, Edgewise's lead drug, remains unchanged in its potential, with ongoing pivotal studies for Becker Muscular Dystrophy. Edgewise stock has surged over 50% today however on Phase 1 data for EDG-7500, a cardiac sarcomere modulator for hypertrophic cardiomyopathy and diastolic dysfunction. The positive Phase 1 data for EDG-7500 significantly impacts Edgewise's valuation, highlighting the importance of considering early-stage assets. There is a long path to a potential approval shot, however, and the reliability of a 7-patient data set is not sufficient for a "buy" recommendation at this time. One for the watchlist. Read the full article on Seeking Alpha
Analysis Article • Aug 12

We Think Edgewise Therapeutics (NASDAQ:EWTX) Can Afford To Drive Business Growth

There's no doubt that money can be made by owning shares of unprofitable businesses. By way of example, Edgewise...
Seeking Alpha • Aug 05

Edgewise Therapeutics: Strong Open Label Data Makes For A Bullish Signal

Summary Edgewise Therapeutics develops small molecules for myopathies, with lead molecule sevasemten in phase 3 for Becker Muscular Dystrophy. Company was founded in 2017, backed by OrbiMed, with an experienced management team and strong financials. Sevasemten offers a genotype-agnostic approach, competitive difference from dystrophin-targeting therapies, with potential high market valuation. Read the full article on Seeking Alpha
Seeking Alpha • May 10

Edgewise: Intriguing Drug Candidate, But Consider Selling After Recent Run

Summary Edgewise Therapeutics, Inc. reported its first quarter earnings, revealing a strong cash position of $532m and a net loss of $(28.5m). The company is advancing two clinical-stage programs, including a pivotal trial for Becker muscular dystrophy and a Phase 1 trial for hypertrophic cardiomyopathy for a second candidate. Sevasemten, the lead drug candidate, showed positive results in a two-year study for Becker muscular dystrophy, supporting the hypothesis that it can preserve and improve muscle function. An FDA Fast Track designation for sevasemten has triggered a bull run that has seen the share price gain by >250%. A lack of genuinely meaningful catalysts in 2024, and a lengthy wait until an application for approval can be made, make this a good time to sell, in my view, although long-term, there are signs the drug is approvable. Read the full article on Seeking Alpha
Analysis Article • May 10

We're Not Very Worried About Edgewise Therapeutics' (NASDAQ:EWTX) Cash Burn Rate

We can readily understand why investors are attracted to unprofitable companies. For example, Edgewise Therapeutics...
Seeking Alpha • Feb 18

Edgewise Therapeutics: Behind The Massive Rally

Summary Edgewise Therapeutics' stock has rallied massively after receiving FDA designations for its lead asset, EDG-5506, which has a potential $750 million opportunity in BMD. The company is focused on developing precision medicines for severe genetic neuromuscular and cardiac disorders. Edgewise Therapeutics has recently raised additional capital and has four data readouts for EDG-5506 scheduled for 2024. A full investment analysis around Edgewise Therapeutics follows in the paragraphs below. Read the full article on Seeking Alpha
Analysis Article • Dec 07

Companies Like Edgewise Therapeutics (NASDAQ:EWTX) Are In A Position To Invest In Growth

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Analysis Article • Aug 16

Edgewise Therapeutics (NASDAQ:EWTX) Is In A Good Position To Deliver On Growth Plans

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Analysis Article • Apr 28

Companies Like Edgewise Therapeutics (NASDAQ:EWTX) Are In A Position To Invest In Growth

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, biotech and mining...
Analysis Article • Jan 13

We Think Edgewise Therapeutics (NASDAQ:EWTX) Can Afford To Drive Business Growth

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Seeking Alpha • Sep 13

Edgewise Therapeutics proposes $100M stock offering plan

Edgewise Therapeutics (NASDAQ:EWTX) announced Tuesday its plans to raise $100M in the underwritten public stock offering; price, size and other terms not yet determined. The Colorado-based biopharmaceutical company told underwriters will be granted an overallotment option to purchase up to an additional $15M shares. It comes right after Edgewise Therapeutics received FDA's approval for phase 2 trial of its experimental drug, EDG-5506, in children with muscular dystrophy. Stock is down 2% in pre-market trading.
Seeking Alpha • Aug 04

Edgewise Therapeutics GAAP EPS of -$0.32 beats by $0.02

Edgewise Therapeutics press release (NASDAQ:EWTX): Q2 GAAP EPS of -$0.32 beats by $0.02. Cash, cash equivalents and marketable securities of $248.4 million as of June 30, 2022
Analysis Article • Aug 02

Companies Like Edgewise Therapeutics (NASDAQ:EWTX) Are In A Position To Invest In Growth

Just because a business does not make any money, does not mean that the stock will go down. For example, although...

Shareholder Returns

EWTXUS PharmaceuticalsUS Market
7D6.8%2.6%2.5%
1Y134.3%41.5%26.4%

Return vs Industry: EWTX exceeded the US Pharmaceuticals industry which returned 44.3% over the past year.

Return vs Market: EWTX exceeded the US Market which returned 28.7% over the past year.

Price Volatility

Is EWTX's price volatile compared to industry and market?
EWTX volatility
EWTX Average Weekly Movement8.3%
Pharmaceuticals Industry Average Movement9.9%
Market Average Movement7.2%
10% most volatile stocks in US Market16.5%
10% least volatile stocks in US Market3.1%

Stable Share Price: EWTX has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: EWTX's weekly volatility (8%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
2017154Kevin Kochedgewisetx.com

Edgewise Therapeutics, Inc., a biopharmaceutical company, discovers, develops, and commercializes therapies for the treatment of muscle disorders. Its lead product candidate, sevasemten, an orally administered small molecule that is in Phase II clinical trials, designed to address the root cause of dystrophinopathies including Duchenne muscular dystrophy and Becker muscular dystrophy. The company develops EDG-7500, a small molecule for the treatment of hypertrophic cardiomyopathy and other severe cardiac disorders that is in Phase I clinical trials; and EDG-15400, a novel small molecule for the treatment of heart failure with preserved ejection fraction.

Edgewise Therapeutics, Inc. Fundamentals Summary

How do Edgewise Therapeutics's earnings and revenue compare to its market cap?
EWTX fundamental statistics
Market capUS$3.52b
Earnings (TTM)-US$176.01m
Revenue (TTM)n/a
0.0x
P/S Ratio
-20.5x
P/E Ratio

Is EWTX overvalued?

See Fair Value and valuation analysis

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
EWTX income statement (TTM)
RevenueUS$0
Cost of RevenueUS$0
Gross ProfitUS$0
Other ExpensesUS$176.01m
Earnings-US$176.01m

Last Reported Earnings

Mar 31, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-1.64
Gross Margin0.00%
Net Profit Margin0.00%
Debt/Equity Ratio0%

How did EWTX perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/26 06:32
End of Day Share Price 2026/05/26 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Edgewise Therapeutics, Inc. is covered by 14 analysts. 12 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Cory KasimovEvercore ISI
Paul ChoiGoldman Sachs
Debjit ChattopadhyayGuggenheim Securities, LLC