REGENXBIO Management
Management criteria checks 4/4
We currently do not have sufficient information about the CEO.
Key information
Curran Simpson
Chief executive officer
US$4.2m
Total compensation
| CEO salary percentage | 15.84% |
| CEO tenure | 2yrs |
| CEO ownership | 0.09% |
| Management average tenure | 7.3yrs |
| Board average tenure | 9yrs |
Recent management updates
Recent updates
Seeking Alpha • Jun 28
Regenxbio: 'Strong Buy' On FDA Course Reversal For NAVSUNLI And Potential AA DMD Filing
Summary REGENXBIO upgraded to 'Strong Buy' on FDA's course reversal for rare disease therapies, notably impacting NAVSUNLI [RGX-121] for MPS II. Company expects to resubmit NAVSUNLI BLA in Q3 2026, leveraging robust CAMPSIITE trial data and no new study requirements per FDA alignment. RGX-202 for DMD and sura-vec for wet AMD offer additional catalysts, with pivotal trial data and regulatory submissions anticipated through 2027. Company faces a cash runway into early 2027, but milestone payments, PRV monetization, and an ATM facility provide potential funding options. Read the full article on Seeking Alpha
Narrative Update • Jun 15
RGNX: Future Duchenne Regulatory Outcomes Will Test Gene Therapy Bullish Thesis
Narrative Update on REGENXBIO The analyst price target for REGENXBIO in this framework moves from $12.00 to $10.00 as analysts factor in recent target cuts tied to a higher projected share count and continued regulatory uncertainty around RGX-202 in Duchenne muscular dystrophy. At the same time, they acknowledge encouraging functional data and a higher assumed profit margin.
Narrative Update • Jun 01
RGNX: AFFINITY DUCHENNE Data Will Shape Future Regulatory And Share Price Upside
Analysts have trimmed the implied fair value on REGENXBIO stock from about $29.75 to roughly $24.18. This reflects a cluster of lower Street price targets in the $12 to $42 range as they factor in a higher discount rate, updated views on RGX-202 regulatory uncertainty, and revised expectations for revenue growth, profit margins, and future P/E.Narrative Update • Apr 26
RGNX: Future Gene Therapy Milestones Will Test Regulatory Risk And Support Bullish Reassessment
REGENXBIO's consensus analyst price target has been revised lower, with cuts ranging from about $1 to $12 as analysts factor in updated clinical timelines, recent FDA commentary around RGX-121 and the approach to rare disease, as well as upcoming pivotal readouts for key gene therapy programs. Analyst Commentary Recent research updates show that while several firms still carry positive ratings on REGENXBIO, they have been trimming price targets and highlighting a more cautious setup around regulatory risk, clinical execution, and timelines for key programs.Narrative Update • Apr 11
RGNX: Future Pivotal Gene Therapy Readouts Will Drive Bullish Reassessment
Analysts have nudged their average price target for REGENXBIO slightly lower to reflect recent target cuts across firms, while still highlighting upcoming regulatory updates and pivotal readouts in Duchenne muscular dystrophy and wet age related macular degeneration as key drivers for their updated views. Analyst Commentary Recent research updates show that while upcoming data and regulatory milestones remain central to the REGENXBIO story, several price targets have been adjusted lower following the latest quarterly results and clinical updates.Narrative Update • Mar 28
RGNX: Future Gene Therapy Milestones Will Drive Reassessment Despite Regulatory Uncertainty
Analysts have nudged their blended price target for REGENXBIO modestly lower by a few dollars to reflect recent reductions in firm level targets, while still pointing to upcoming regulatory updates and pivotal readouts across programs like RGX-202 and ABBV-RGX-314 as key factors in their outlook. Analyst Commentary Street research around REGENXBIO has tilted more cautious in recent weeks, with several price targets adjusted lower following the latest quarterly update, recent regulatory news and evolving views on the company’s gene therapy portfolio.Narrative Update • Mar 12
RGNX: Future Gene Therapy Readouts Will Drive Reassessment Despite Regulatory Setbacks
Analysts have trimmed their average price targets on REGENXBIO, with cuts such as $32 to $30, $45 to $42 and $18 to $17. These changes reflect updated assumptions for slightly lower revenue growth and profit margins, partly offset by a modestly lower discount rate and a higher future P/E multiple.Narrative Update • Feb 26
RGNX: Regulatory Resolution And Gene Therapy Data Will Drive Reassessment
Analysts have trimmed their price targets on REGENXBIO by up to $12, reflecting updated views on RGX-121 related regulatory uncertainty and revised assumptions for the discount rate, revenue growth, profit margin and future P/E, while the central fair value estimate remains at $12.00. Analyst Commentary Recent research updates around REGENXBIO have centered on RGX-121 and the regulatory commentary that investors are trying to interpret.Narrative Update • Feb 11
RGNX: Clinical Hold Setbacks Will Refocus Attention On Upcoming Pivotal Data
Analysts have trimmed their fair value estimate for REGENXBIO to $12.00 from $14.00, citing a reset in price targets across the Street following clinical updates. The revised estimate still reflects higher modeled revenue growth and a lower future P/E multiple in their assumptions.Analysis Article • Feb 06
REGENXBIO Inc. (NASDAQ:RGNX) Looks Inexpensive After Falling 28% But Perhaps Not Attractive Enough
REGENXBIO Inc. ( NASDAQ:RGNX ) shareholders won't be pleased to see that the share price has had a very rough month...Analysis Article • Jan 29
Is REGENXBIO (NASDAQ:RGNX) Weighed On By Its Debt Load?
David Iben put it well when he said, 'Volatility is not a risk we care about. What we care about is avoiding the...Analysis Article • Dec 23
REGENXBIO Inc. (NASDAQ:RGNX) Surges 27% Yet Its Low P/S Is No Reason For Excitement
REGENXBIO Inc. ( NASDAQ:RGNX ) shares have continued their recent momentum with a 27% gain in the last month alone. The...Analysis Article • Oct 09
REGENXBIO Inc. (NASDAQ:RGNX) Held Back By Insufficient Growth Even After Shares Climb 29%
REGENXBIO Inc. ( NASDAQ:RGNX ) shares have continued their recent momentum with a 29% gain in the last month alone...Analysis Article • Oct 03
Is REGENXBIO (NASDAQ:RGNX) A Risky Investment?
David Iben put it well when he said, 'Volatility is not a risk we care about. What we care about is avoiding the...Analysis Article • Aug 12
Investors Don't See Light At End Of REGENXBIO Inc.'s (NASDAQ:RGNX) Tunnel
NasdaqGS:RGNX 1 Year Share Price vs Fair Value Explore REGENXBIO's Fair Values from the Community and select yours With...Narrative Update • Aug 08
Gene Therapy Breakthroughs Will Unlock Expanding Future Markets
Analysts have revised REGENXBIO’s price target downward to $29.75, reflecting heightened sector scrutiny after competitor safety issues but maintaining confidence in RGX-202’s differentiated immune suppression strategy and clinical outlook. Analyst Commentary Safety issues with a competitor's product (Sarepta's Elevidys) have renewed focus on immune prophylaxis, highlighting Regenxbio's proactive approach to immune suppression with RGX-202.Analysis Article • May 15
REGENXBIO Inc. Just Missed EPS By 64%: Here's What Analysts Think Will Happen Next
It's shaping up to be a tough period for REGENXBIO Inc. ( NASDAQ:RGNX ), which a week ago released some disappointing...Analysis Article • May 01
REGENXBIO Inc. (NASDAQ:RGNX) Shares Fly 34% But Investors Aren't Buying For Growth
REGENXBIO Inc. ( NASDAQ:RGNX ) shareholders would be excited to see that the share price has had a great month, posting...Analysis Article • Apr 24
Is REGENXBIO (NASDAQ:RGNX) A Risky Investment?
The external fund manager backed by Berkshire Hathaway's Charlie Munger, Li Lu, makes no bones about it when he says...
New Narrative • Mar 30
FDA Approval And Nippon Shinyaku Partnership Will Advance Pipeline
Strategic partnerships and FDA approvals drive potential revenue growth through new market penetrations and milestone payments.Seeking Alpha • Mar 26
5 Reasons To Buy Regenxbio Right Now
Summary Regenxbio Inc. is rated a "Strong Buy" due to many reasons reasons, some of those have nothing/little to do (directly) with pipeline or clinical trials. RGNX has an extremely low Enterprise Value, with potential for the EV to turn negative once upcoming scheduled/milestone payments and royalties come in. RGNX benefits from strategic partnerships, including $110M from Nippon Shinyaku and $200M from AbbVie, plus potential higher royalties from Novartis. Technically speaking, the stock is shifting from bearish to bullish, with significant upside potential and positive price target trends from multiple analysts. RGNX is a prime buyout candidate, with AbbVie as a likely bidder, supported by several other potential suitors in the biotech and pharma sectors that are active/interested in Gene Therapy. Read the full article on Seeking AlphaAnalysis Article • Mar 04
The Market Doesn't Like What It Sees From REGENXBIO Inc.'s (NASDAQ:RGNX) Revenues Yet As Shares Tumble 27%
To the annoyance of some shareholders, REGENXBIO Inc. ( NASDAQ:RGNX ) shares are down a considerable 27% in the last...Seeking Alpha • Jan 15
Regenxbio Inc.: Why It Is Down, And When It Will Go Up Again
Summary Regenxbio Inc. remains undervalued despite its cutting-edge AAV gene therapy technology and promising assets like RGX-314 for wet AMD and RGX-121 for MPS II. RGX-314, partnered with AbbVie, targets wet AMD with global regulatory submissions expected in H1 2026; RGX-121 has a rolling BLA submission expected to complete in Q1 2025. Financially, RGNX has a market cap of $344mn and a cash balance of $279mn, bolstered by a recent $110mn upfront fee from Nippon Shinyaku. Despite historical underperformance, I remain hopeful, banking on the durability of their wet AMD treatment and will continue buying at dips, giving RGNX stock two more years. Read the full article on Seeking AlphaAnalysis Article • Dec 28
Revenues Working Against REGENXBIO Inc.'s (NASDAQ:RGNX) Share Price Following 26% Dive
Unfortunately for some shareholders, the REGENXBIO Inc. ( NASDAQ:RGNX ) share price has dived 26% in the last thirty...Seeking Alpha • Oct 31
REGENXBIO: With Additional MPS II Data, Program Advancement Remains On Track
Summary Positive updated long-term results from phase I/II/III CAMPSITE study using RGX-121 for the treatment of patients with MPS II. Rolling BLA submission of RGX-121 for the treatment of patients with MPS II expected any day now in Q4 of 2024. The global Hunter Syndrome treatment market is expected to reach $1.78 billion by 2030. RGX-202 for the treatment of patients with DMD and ABBV-RGX-314 for treatment of patients with diabetic retinopathy are other programs in pipeline; Late-stage studies starting Q4 of 2024 and 1st half 2025 respectively. Read the full article on Seeking AlphaAnalysis Article • Sep 12
Does REGENXBIO (NASDAQ:RGNX) Have A Healthy Balance Sheet?
Some say volatility, rather than debt, is the best way to think about risk as an investor, but Warren Buffett famously...Seeking Alpha • Aug 06
Regenxbio: RGX-121 Could Achieve A First For Rare Neurodegenerative Disorder
Summary Regenxbio Inc.'s rolling BLA submission of RGX-121 for the treatment of patients with MPS II expected in Q3 of 2024. Additional results from the phase 1/2/3 CAMPSIITE study, using RGX-121 for the treatment of patients with MPS II, expected in the 2nd half of 2024. Initiation of a pivotal study, using RGX-202 for the treatment of patients with Duchenne Muscular Dystrophy, expected in Q4 of 2024. Subretinal delivery of ABBV-RGX-314 for the treatment of patients with Wet-AMD is ongoing; Two studies being done are ATMOSPHERE and ASCENT and regulatory submissions U.S. And EU on track for 1st half of 2026. Read the full article on Seeking AlphaAnalysis Article • Aug 04
REGENXBIO Inc. (NASDAQ:RGNX) Second-Quarter Results: Here's What Analysts Are Forecasting For This Year
Shareholders might have noticed that REGENXBIO Inc. ( NASDAQ:RGNX ) filed its quarterly result this time last week. The...Analysis Article • Jul 26
Revenues Working Against REGENXBIO Inc.'s (NASDAQ:RGNX) Share Price
REGENXBIO Inc.'s ( NASDAQ:RGNX ) price-to-sales (or "P/S") ratio of 8.2x might make it look like a buy right now...Seeking Alpha • Jun 11
Regenxbio: Transforming Gene Therapy With Innovative AAV Treatments, Strong Buy
Summary REGENXBIO develops AAV therapies using its proprietary NAV platform, offering one-dose treatments targeting disease root causes. The company's pipeline includes promising candidates for age-related macular degeneration, Duchenne muscular dystrophy, and Hunter syndrome. ABBV-RGX-314, RGX-202, and RGX-121 are key pipeline candidates targeting significant markets with promising clinical data. The collaboration with AbbVie for ABBV-RGX-314 includes potential milestone payments and significant market potential in wet AMD and DR. I deem RGNX a "strong buy" due to its innovative pipeline, strategic partnerships, robust financial health, and potential market impact. Read the full article on Seeking AlphaCEO Compensation Analysis
| Date | Total Compensation | Salary | Company Earnings |
|---|---|---|---|
| Mar 31 2026 | n/a | n/a | -US$290m |
| Dec 31 2025 | US$4m | US$666k | -US$194m |
| Sep 30 2025 | n/a | n/a | -US$178m |
| Jun 30 2025 | n/a | n/a | -US$176m |
| Mar 31 2025 | n/a | n/a | -US$158m |
| Dec 31 2024 | US$5m | US$572k | -US$227m |
| Sep 30 2024 | n/a | n/a | -US$239m |
| Jun 30 2024 | n/a | n/a | -US$241m |
| Mar 31 2024 | n/a | n/a | -US$260m |
| Dec 31 2023 | US$3m | US$513k | -US$263m |
| Sep 30 2023 | n/a | n/a | -US$261m |
| Jun 30 2023 | n/a | n/a | -US$274m |
| Mar 31 2023 | n/a | n/a | -US$270m |
| Dec 31 2022 | US$2m | US$475k | -US$280m |
| Sep 30 2022 | n/a | n/a | US$74m |
| Jun 30 2022 | n/a | n/a | US$91m |
| Mar 31 2022 | n/a | n/a | US$101m |
| Dec 31 2021 | US$3m | US$448k | US$128m |
| Sep 30 2021 | n/a | n/a | -US$212m |
| Jun 30 2021 | n/a | n/a | -US$145m |
| Mar 31 2021 | n/a | n/a | -US$121m |
| Dec 31 2020 | US$2m | US$428k | -US$111m |
| Sep 30 2020 | n/a | n/a | -US$91m |
| Jun 30 2020 | n/a | n/a | -US$135m |
| Mar 31 2020 | n/a | n/a | -US$103m |
| Dec 31 2019 | US$2m | US$382k | -US$95m |
Compensation vs Market: Curran's total compensation ($USD4.20M) is about average for companies of similar size in the US market ($USD3.54M).
Compensation vs Earnings: Curran's compensation has been consistent with company performance over the past year.
CEO
Curran Simpson (64 yo)
2yrs
Tenure
US$4,200,712
Compensation
Mr. Curran M. Simpson, M.S., had been the Chief Operating Officer at REGENXBIO Inc. since January 2023 until July 01, 2024 and served as its Executive Vice President until July 01, 2024 and serves as its P...
Leadership Team
| Name | Position | Tenure | Compensation | Ownership |
|---|---|---|---|---|
| President | 2yrs | US$4.20m | 0.089% $ 608.3k | |
| Executive VP & Chief Strategy and Legal Officer | 9.9yrs | US$2.04m | 0.17% $ 1.2m | |
| Executive VP & Chief Medical Officer | 7.3yrs | US$1.80m | 0.088% $ 606.6k | |
| Executive VP & CFO | 1.8yrs | US$3.21m | 0.019% $ 130.4k | |
| Executive VP of Product Development & CTO | 1.3yrs | no data | 0.16% $ 1.1m | |
| Executive VP & Chief Scientific Officer | 9.3yrs | US$2.96m | 0.11% $ 775.1k | |
| Chief Communications & People Officer | 8.8yrs | no data | no data | |
| Executive VP & Chief Commercial Officer | 7.9yrs | no data | no data | |
| SVP of Global Regulatory Strategy and Quality | less than a year | no data | no data | |
| Clinical Development Lead | no data | no data | no data |
7.3yrs
Average Tenure
55yo
Average Age
Experienced Management: RGNX's management team is seasoned and experienced (7.3 years average tenure).
Board Members
| Name | Position | Tenure | Compensation | Ownership |
|---|---|---|---|---|
| President | 2yrs | US$4.20m | 0.089% $ 608.3k | |
| Independent Director | 10.8yrs | US$339.99k | 0.037% $ 253.1k | |
| Independent Director | 4.8yrs | US$339.99k | 0.037% $ 253.1k | |
| Independent Director | 11.2yrs | US$327.49k | 0.037% $ 253.1k | |
| Member of Scientific Advisor | no data | no data | no data | |
| Independent Director | 17.4yrs | US$319.99k | 6.15% $ 42.2m | |
| Member of Scientific Advisor | no data | no data | no data | |
| Independent Director | 8.2yrs | US$327.49k | 0.037% $ 253.1k | |
| Lead Independent Director | 9.9yrs | US$359.99k | 0.037% $ 253.1k | |
| Independent Director | 4.8yrs | US$324.99k | 0.037% $ 253.1k | |
| Chairman | 17.3yrs | US$354.99k | 0.85% $ 5.8m | |
| Independent Director | 4.1yrs | US$329.99k | 0.043% $ 293.0k |
9.0yrs
Average Tenure
71.5yo
Average Age
Experienced Board: RGNX's board of directors are considered experienced (9 years average tenure).
Company Analysis and Financial Data Status
| Data | Last Updated (UTC time) |
|---|---|
| Company Analysis | 2026/07/06 06:35 |
| End of Day Share Price | 2026/07/06 00:00 |
| Earnings | 2026/03/31 |
| Annual Earnings | 2025/12/31 |
Data Sources
The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.
| Package | Data | Timeframe | Example US Source * |
|---|---|---|---|
| Company Financials | 10 years |
| |
| Analyst Consensus Estimates | +3 years |
|
|
| Market Prices | 30 years |
| |
| Ownership | 10 years |
| |
| Management | 10 years |
| |
| Key Developments | 10 years |
|
* Example for US securities, for non-US equivalent regulatory forms and sources are used.
Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.
Analysis Model and Snowflake
Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.
Learn about the world class team who designed and built the Simply Wall St analysis model.
Industry and Sector Metrics
Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.
Analyst Sources
REGENXBIO Inc. is covered by 23 analysts. 10 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.
| Analyst | Institution |
|---|---|
| Brian Skorney | Baird |
| Huidong Wang | Barclays |
| Eliana Merle | Barclays |