NasdaqGS:AGIOBiotechs
Agios Pharmaceuticals (AGIO) Is Down 7.7% After Halting Tebapivat While Advancing Mitapivat in Sickle Cell Disease – Has The Bull Case Changed?
Agios Pharmaceuticals recently reported topline Phase 2 results for tebapivat in sickle cell disease and, citing insufficient differentiation versus other pyruvate kinase activators, decided to halt further development in this indication despite observing hemoglobin and hemolysis improvements and a safety profile aligned with prior trials.
At the same time, the company is pursuing an alternative path in sickle cell disease through the FDA’s Priority Review of a supplemental New Drug...