Prothena (PRTA) Panoramica del titolo
Prothena Corporation plc, società di biotecnologie cliniche in fase avanzata, si concentra sulla scoperta e sullo sviluppo di nuove terapie per il trattamento di malattie causate dalla disregolazione delle proteine. Maggiori dettagli
| Punteggio fiocco di neve | |
|---|---|
| Valutazione | 4/6 |
| Crescita futura | 5/6 |
| Prestazioni passate | 0/6 |
| Salute finanziaria | 5/6 |
| Dividendi | 0/6 |
Premi
Analisi del rischio
Non sono stati rilevati rischi per PRTA dai nostri controlli di rischio.
PRTA Community Fair Values
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Analyst Price Targets
Concorrenti di Prothena Corporation plc
Storia dei prezzi e prestazioni
| Prezzi storici delle azioni | |
|---|---|
| Prezzo attuale dell'azione | US$9.69 |
| Massimo di 52 settimane | US$11.80 |
| Minimo di 52 settimane | US$6.16 |
| Beta | -0.31 |
| Variazione di 1 mese | 10.24% |
| Variazione a 3 mesi | -3.49% |
| Variazione di 1 anno | 50.58% |
| Variazione a 3 anni | -85.00% |
| Variazione a 5 anni | -83.64% |
| Variazione dall'IPO | 34.58% |
Notizie e aggiornamenti recenti
Aggiornamento della narrazione • Jun 25
PRTA: Fast Track ATTR Cardio Program And Tau Data Will Support Upside
Analysts kept their fair value estimate for Prothena steady at $21.40 while making only minimal model tweaks, citing broader enthusiasm around tau-targeting Alzheimer's therapies following the CELIA Phase 2 data as a key support for the updated price target framework. What’s in the News for Prothena U.S. FDA granted Fast Track Designation to coramitug, an amyloid depleter antibody in Phase 3 development for treating ATTR cardiomyopathy (ATTR-CM), according to Prothena’s update on the Novo Nordisk partnered program.Aggiornamento della narrazione • Jun 04
PRTA: Fast Track ATTR Program And Tau Readthroughs Will Support Future Upside
Analysts have nudged their fair value estimate for Prothena stock from $21.00 to $21.40, citing updated assumptions on long term revenue growth, profit margins, and future P/E multiples following fresh readthroughs from recent Alzheimer's tau data. What's in the News The U.S. FDA granted Fast Track Designation to coramitug, an amyloid depleter antibody in Phase 3 development for ATTR amyloidosis with cardiomyopathy (ATTR-CM).Recent updates
Aggiornamento della narrazione • Jun 25
PRTA: Fast Track ATTR Cardio Program And Tau Data Will Support Upside
Analysts kept their fair value estimate for Prothena steady at $21.40 while making only minimal model tweaks, citing broader enthusiasm around tau-targeting Alzheimer's therapies following the CELIA Phase 2 data as a key support for the updated price target framework. What’s in the News for Prothena U.S. FDA granted Fast Track Designation to coramitug, an amyloid depleter antibody in Phase 3 development for treating ATTR cardiomyopathy (ATTR-CM), according to Prothena’s update on the Novo Nordisk partnered program.Aggiornamento della narrazione • Jun 04
PRTA: Fast Track ATTR Program And Tau Readthroughs Will Support Future Upside
Analysts have nudged their fair value estimate for Prothena stock from $21.00 to $21.40, citing updated assumptions on long term revenue growth, profit margins, and future P/E multiples following fresh readthroughs from recent Alzheimer's tau data. What's in the News The U.S. FDA granted Fast Track Designation to coramitug, an amyloid depleter antibody in Phase 3 development for ATTR amyloidosis with cardiomyopathy (ATTR-CM).Aggiornamento della narrazione • May 09
PRTA: Fast Track ATTR Program And Buybacks Will Support Future Upside
Analysts kept Prothena's fair value estimate steady at $21.00 with only small tweaks to the discount rate and long term assumptions, suggesting their price target is broadly unchanged while refining the supporting model inputs. What's in the News The U.S. FDA granted Fast Track Designation to coramitug, an amyloid depleter antibody in Phase 3 development for transthyretin amyloidosis with cardiomyopathy.Aggiornamento della narrazione • Apr 22
PRTA: ATTR Milestones And Share Repurchase Plan Will Support Future Upside
Analysts maintained Prothena's fair value estimate at $21.00, citing largely unchanged assumptions regarding revenue growth, profit margin, discount rate, and a very large future P/E multiple. What's in the News Prothena has earned $150 million to date out of up to $1.2 billion in eligible milestone payments from Novo Nordisk under their ATTR amyloidosis agreement.Aggiornamento della narrazione • Apr 02
PRTA: ATTR Milestones And Share Repurchase Will Drive Future Upside
Analysts have kept their price target for Prothena broadly unchanged at $21.00, with only slight adjustments to underlying assumptions on discount rate, revenue growth, profit margin and future P/E, in order to better reflect their current view of the stock's risk and earnings profile. What's in the News Prothena has earned $150 million to date of the total eligible milestone payments of up to $1.2 billion from Novo Nordisk under their ATTR amyloidosis agreement, including a recent $50 million milestone tied to a prespecified enrollment target in the ongoing Phase 3 CLEOPATTRA trial of coramitug for ATTR-CM (Key Developments).Aggiornamento della narrazione • Mar 19
PRTA: Share Buyback And ATTR Milestones Will Support Future Upside
Analysts have nudged their price target on Prothena to $21.00 from $20.50, reflecting updated assumptions on growth, margins, and a very large prospective future P/E multiple. What's in the News Prothena has earned a total of $150 million to date from potential milestone payments of up to $1.2 billion under its ATTR amyloidosis agreement with Novo Nordisk, tied to clinical development and sales milestones (Key Developments).Aggiornamento della narrazione • Mar 04
PRTA: Share Buyback And Index Inclusion Will Support Future Upside
Analysts now set their Prothena price target at about $20.50, compared with roughly $20.33 previously. This reflects updated assumptions around revenue growth, profit margins and future P/E levels.
Nuova narrazione • Feb 23
Bullish View Expects Partnered Neurology Pipeline And CYTOPE Platform To Reshape Long-Term Prospects
Catalysts About Prothena Prothena is a late stage biotech company focused on protein misfolding and neurodegenerative diseases through partnered and wholly owned antibody and CYTOPE programs. What are the underlying business or industry changes driving this perspective?Aggiornamento della narrazione • Feb 18
PRTA: Index Inclusion And ALS Platform Milestones Will Drive Future Upside
Analysts maintained their Prothena fair value estimate at $20.33 per share, making only minor adjustments to assumptions such as discount rate, revenue growth, profit margin, and future P/E, which together support this unchanged price target. What's in the News Prothena Corporation plc was added to the S&P Biotechnology Select Industry Index, which can increase visibility for the stock among index-tracking funds and sector-focused investors (Key Developments).Aggiornamento della narrazione • Feb 03
PRTA: Future Milestones From ALS Platform And ATTR Program Will Drive Upside
Analysts have trimmed their price target for Prothena to about US$20.33 per share, reflecting slightly adjusted assumptions around discount rate, profit margin, and future P/E that fine tune rather than overhaul their prior view. What's in the News Prothena was added to the S&P Biotechnology Select Industry Index, putting the stock into a tracked industry benchmark that some index funds and ETFs follow (Index Constituent Adds).Aggiornamento della narrazione • Jan 20
PRTA: Partnered Royalties And Milestones Will Drive Upside Over Next 12 Months
Narrative update Analysts have lifted their price target on Prothena to US$36 from US$15, highlighting the value they see in the partnered pipeline and its potential for net sales royalties and milestone payments over the catalyst-heavy year ahead. Analyst Commentary Bullish analysts are pointing to the recent price target revision to US$36 as a signal that the market may be underappreciating the potential value of Prothena's partnered programs, especially the royalty and milestone streams that could build over time.Aggiornamento della narrazione • Jan 05
PRTA: Partnered Royalties And Milestones Will Drive Upside Over Catalyst-Rich Year
Narrative Update Analysts have raised their price target on Prothena to US$36 from US$15, citing what they describe as strong potential in the company's partnered pipeline, including expected net sales royalties and milestone payments over the coming year and in subsequent periods. Analyst Commentary Recent commentary from bullish analysts centers on the uplift in the price target to US$36, tied directly to how they see Prothena executing on its partnered programs and the potential cash flows that could come from those collaborations.Aggiornamento della narrazione • Dec 18
PRTA: Partnered Pipeline Milestones Will Drive Upside Over Catalyst-Rich Year Ahead
Analysts have significantly raised their price target on Prothena to $36 from $15, reflecting increased confidence in the lucrative potential of its partnered pipeline, including expected net sales royalties, milestone payments, and a catalyst-rich outlook over the next year. Analyst Commentary Bullish analysts highlight that the substantial price target increase is grounded in greater conviction around Prothena's partnered pipeline, which they see as a key driver of long term value creation and multiple expansion.Articolo di analisi • Dec 11
We Think Prothena (NASDAQ:PRTA) Can Afford To Drive Business Growth
Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...Aggiornamento della narrazione • Dec 04
PRTA: Partnered Pipeline Milestones Will Drive Upside Over Catalyst-Rich Year Ahead
Analysts have lifted their fair value estimate for Prothena by about $2 per share, citing stronger long term revenue growth expectations from its partnered pipeline, lucrative royalty and milestone economics, and a robust catalyst calendar that they believe offers substantial upside potential. Analyst Commentary Recent adjustments to Prothena's valuation reflect a growing conviction that the company’s partnered programs and associated economics could materially enhance long term growth, though execution and timing risks remain key variables for investors.Aggiornamento della narrazione • Nov 20
PRTA: Upcoming Partnered Pipeline Milestones Will Drive Substantial Upside Over Next Year
Analysts have increased their price target for Prothena, raising it from $16.50 to $18.33. They cite optimism about the company's partnered pipeline and upcoming catalysts as key drivers for this upward revision.Aggiornamento della narrazione • Nov 05
PRTA: Upcoming Pipeline Milestones Will Drive Bullish Momentum Over Next 12 Months
Analysts have increased their price target for Prothena significantly, raising it from $15 to $36. They cite the company's strong partnered pipeline as well as substantial potential from upcoming catalysts and milestone payments.Aggiornamento della narrazione • Oct 22
Analysts Maintain Prothena Price Target as Valuation Adjustments Reflect Recent Clinical Results
Analysts have marginally raised their price target for Prothena from $13.00 to $13.00. They cited slight adjustments in discount rate and profit margin assumptions as drivers for the updated valuation.Aggiornamento della narrazione • Oct 08
AFFIRM-AL And Alzheimer's Trials Will Unlock New Opportunities
Analysts have raised Prothena's fair value estimate by $1.00 to $13.00, citing improved profit margin forecasts and a slightly lower projected future price-to-earnings ratio. What's in the News Prothena announced results from the Phase 1 ASCENT clinical program for PRX012 in early symptomatic Alzheimer's disease.Aggiornamento della narrazione • Sep 13
AFFIRM-AL And Alzheimer's Trials Will Unlock New Opportunities
Prothena’s consensus price target has been revised down to $12.00, reflecting weaker expectations primarily due to a notable decline in net profit margin and a reduced future P/E multiple. What's in the News Prothena reported Phase 1 ASCENT program results for PRX012 in early symptomatic Alzheimer's, showing stable pharmacokinetics, low immunogenicity, significant amyloid reduction, but higher ARIA-E rates compared to FDA-approved antibodies; company plans to seek partnerships for PRX012 and PRX012-TfR.Aggiornamento della narrazione • Aug 29
AFFIRM-AL And Alzheimer's Trials Will Unlock New Opportunities
Despite a sharp upward revision in both revenue growth and net profit margin forecasts for Prothena, the consensus analyst price target has significantly decreased from $24.29 to $15.00. What's in the News Phase 1 ASCENT results for PRX012 in early symptomatic Alzheimer's showed promising amyloid plaque reduction and pharmacokinetics, but higher ARIA-E rates than approved therapies; Prothena will seek partnership to advance PRX012 and its preclinical Ab-TfR antibody.Articolo di analisi • May 29
The Prothena Corporation plc (NASDAQ:PRTA) Analysts Have Been Trimming Their Sales Forecasts
One thing we could say about the analysts on Prothena Corporation plc ( NASDAQ:PRTA ) - they aren't optimistic, having...Seeking Alpha • May 27
Prothena: Despite Phase 3 Trial Failure, Other Neurodegenerative Programs In Place
Summary Prothena Corporation plc's phase 3 AFFIRM-AL trial for birtamimab in AL amyloidosis failed, leading to program termination and workforce reduction. Despite Phase 3 AL Amyloidosis trial failure, I maintain a Hold rating due to Prothena's robust pipeline, including Alzheimer's, Parkinson's, and ATTR-CM candidates. Key near-term catalysts include phase 1 PRX012 Alzheimer's data mid-2025 and other releases going forward, plus data updates for candidates prasinezumab and coramitug for PD and ATTR-CM. The Alzheimer's Disease market, in the 8 major markets [8MM] is expected to reach $19.3 billion by 2033; About between 5% to 6% of AD patients are early-symptomatic. Read the full article on Seeking AlphaArticolo di analisi • May 22
Why Investors Shouldn't Be Surprised By Prothena Corporation plc's (NASDAQ:PRTA) 27% Share Price Plunge
Unfortunately for some shareholders, the Prothena Corporation plc ( NASDAQ:PRTA ) share price has dived 27% in the last...Articolo di analisi • Apr 02
Benign Growth For Prothena Corporation plc (NASDAQ:PRTA) Underpins Stock's 26% Plummet
Prothena Corporation plc ( NASDAQ:PRTA ) shares have had a horrible month, losing 26% after a relatively good period...
Nuova narrazione • Mar 26
AFFIRM-AL And Alzheimer's Trials Will Unlock New Opportunities
Successful clinical trials for Birtamimab and Alzheimer's treatments could significantly boost Prothena's revenue through large market opportunities.Seeking Alpha • Mar 03
Prothena Corporation: Multiple Failures Make It Risky
Summary Prothena Corporation focuses on neurodegenerative diseases with a diverse pipeline, including Birtamimab for AL amyloidosis, which is in a phase 3 trial. Despite past trial failures, Birtamimab showed a survival benefit in severe AL amyloidosis patients, leading to a new phase 3 study. Financially, Prothena has a market cap of $850mn and a cash runway of 5-10 quarters, but is heavily spending on R&D. I recommend avoiding PRTA due to unpredictable upcoming data and past trial failures, making it risky and potentially un-investible. Read the full article on Seeking AlphaArticolo di analisi • Feb 22
Prothena Corporation plc (NASDAQ:PRTA) Just Released Its Yearly Earnings: Here's What Analysts Think
It's been a good week for Prothena Corporation plc ( NASDAQ:PRTA ) shareholders, because the company has just released...Articolo di analisi • Jan 24
Insufficient Growth At Prothena Corporation plc (NASDAQ:PRTA) Hampers Share Price
With a price-to-sales (or "P/S") ratio of 6.2x Prothena Corporation plc ( NASDAQ:PRTA ) may be sending bullish signals...Seeking Alpha • Dec 22
Prothena Surges After Parkinson's Drug Misses Primary Endpoint
Summary Prothena's stock surged 34% despite Prasinezumab missing its Phase IIb primary endpoint, as Roche continues to invest. Prothena's pipeline includes multiple clinically staged drugs, with partnerships with major pharma companies, offering high-risk/high-reward potential. Investors should be cautious due to Prothena's 61% stock decline in 2024, but meaningful clinical success could create a buying opportunity. Prothena is rated as a HOLD, with upcoming catalysts in Parkinson's and Alzheimer's diseases that could fuel significant price appreciation. Read the full article on Seeking AlphaArticolo di analisi • Nov 06
Prothena (NASDAQ:PRTA) Is In A Good Position To Deliver On Growth Plans
Just because a business does not make any money, does not mean that the stock will go down. For example, biotech and...Seeking Alpha • Oct 18
Prothena: Delays And Data Uncertainty Undermine Case For Investing (Downgrade)
Summary Prothena Corporation plc's stock has dropped 67% since my last “Buy” rating, primarily due to delays and a lack of meaningful Phase 1 data for PRX012. PRX012, targeting amyloid beta for Alzheimer's, is Prothena's key value driver but remains in Phase 1, lagging competitors with similar drugs. Birtamimab's Phase 3 data has also faced delays, and while promising, it competes in a crowded market with limited patient populations. Despite a strong cash position, Prothena's pipeline progress and competitive landscape justify a downgrade to “Hold” until more substantial data is available. Read the full article on Seeking AlphaArticolo di analisi • Oct 02
Prothena Corporation plc (NASDAQ:PRTA) Looks Inexpensive After Falling 25% But Perhaps Not Attractive Enough
Prothena Corporation plc ( NASDAQ:PRTA ) shareholders won't be pleased to see that the share price has had a very rough...Articolo di analisi • Jul 26
Unpleasant Surprises Could Be In Store For Prothena Corporation plc's (NASDAQ:PRTA) Shares
You may think that with a price-to-sales (or "P/S") ratio of 14.9x Prothena Corporation plc ( NASDAQ:PRTA ) is a stock...Articolo di analisi • Jun 19
Companies Like Prothena (NASDAQ:PRTA) Are In A Position To Invest In Growth
There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...Seeking Alpha • Jun 07
Prothena: Potential For Future Price Drop On Failure Risk Of Late-Stage Trials
Summary Prothena Corporation is a late-stage biotech which specializes in proteinopathies and neurodegenerative diseases. They have a diverse pipeline. However, their main assets in attention currently are a first-in-class amyloid depleter, Birtamimab (wholly owned), and a Parkinson’s a-synuclein mAb, Prasinezumab (collab with Roche). Their revenue is primarily dependent on key milestone payments from collaborators. The stock has been dropping since its peak about a year ago, and I believe it still has room to drop for the foreseeable future due to the risk of failure of late-stage trials. Read the full article on Seeking AlphaArticolo di analisi • May 14
New Forecasts: Here's What Analysts Think The Future Holds For Prothena Corporation plc (NASDAQ:PRTA)
Prothena Corporation plc ( NASDAQ:PRTA ) shareholders will have a reason to smile today, with the analysts making...Seeking Alpha • Feb 23
Prothena: Alzheimer's Data Update In 2024 Could Move The Needle
Summary Prothena Corporation plc has an update coming on the phase 1 study using PRX012 for the treatment of patients with Alzheimer's Disease, expected in 2024. Company is already in the process of exploring the use of PRX012 for the treatment of patients with Alzheimer's Disease in the ongoing phase 3 ASCENT-2 study. The global market for Alzheimer's Disease is estimated to reach $15.5 billion by 2031. BMS-986446 is being advanced in collaboration with Bristol-Myers Squibb with the big pharma having taken over the program going forward; Prothena received a $55 million milestone payment based off of it. Read the full article on Seeking AlphaRendimenti per gli azionisti
| PRTA | US Biotechs | US Mercato | |
|---|---|---|---|
| 7D | -3.3% | 4.1% | 1.6% |
| 1Y | 50.6% | 41.1% | 18.6% |
Ritorno vs Industria: PRTA ha superato il US Biotechs che ha restituito 41.1 % nell'ultimo anno.
Rendimento vs Mercato: PRTA ha superato il mercato US che ha restituito 18.6 % nell'ultimo anno.
Volatilità dei prezzi
| PRTA volatility | |
|---|---|
| PRTA Average Weekly Movement | 7.6% |
| Biotechs Industry Average Movement | 10.3% |
| Market Average Movement | 7.3% |
| 10% most volatile stocks in US Market | 16.7% |
| 10% least volatile stocks in US Market | 3.2% |
Prezzo delle azioni stabile: PRTA non ha avuto una volatilità dei prezzi significativa negli ultimi 3 mesi rispetto al mercato US.
Volatilità nel tempo: La volatilità settimanale ( 8% ) di PRTA è rimasta stabile nell'ultimo anno.
Informazioni sull'azienda
| Fondato | I dipendenti | AMMINISTRATORE DELEGATO | Sito web |
|---|---|---|---|
| 2012 | 67 | Gene Kinney | www.prothena.com |
Prothena Corporation plc, società di biotecnologie cliniche in fase avanzata, si concentra sulla scoperta e sullo sviluppo di nuove terapie per il trattamento di malattie causate dalla disregolazione delle proteine. La sua pipeline di prodotti comprende Prasinezumab, un anticorpo monoclonale umanizzato in fase di sperimentazione che è in fase 3 di sperimentazione clinica per il trattamento del morbo di Parkinson e di altre sinucleinopatie. L'azienda sviluppa anche Coramitug, un anticorpo in fase di sperimentazione, che è in fase 3 di sperimentazione clinica per il trattamento dell'amiloidosi da transtiretina; BMS-986446, un anticorpo anti-tau che è in fase 2 di sperimentazione clinica per il trattamento della malattia di Alzheimer; PRX019, un anticorpo in fase di sperimentazione che è in fase 1 di sperimentazione clinica per il trattamento delle malattie neurodegenerative; e PRX123, un vaccino doppio Aß-Tau, che è in fase di sperimentazione preclinica per il trattamento della malattia di Alzheimer.
Prothena Corporation plc Riepilogo dei fondamenti
| PRTA statistiche fondamentali | |
|---|---|
| Capitalizzazione di mercato | US$507.30m |
| Utili (TTM) | -US$151.18m |
| Ricavi(TTM) | US$57.94m |
8.8x
Rapporto P/S-3.4x
Rapporto P/EPRTA è sopravvalutato?
Vedi Fair Value e analisi di valutazioneUtili e ricavi
| PRTA Conto economico (TTM) | |
|---|---|
| Ricavi | US$57.94m |
| Costo del fatturato | US$96.67m |
| Profitto lordo | -US$38.73m |
| Altre spese | US$112.45m |
| Utili | -US$151.18m |
Ultimi utili riportati
Mar 31, 2026
Prossima data di guadagno
n/a
| Utile per azione (EPS) | -2.89 |
| Margine lordo | -66.84% |
| Margine di profitto netto | -260.92% |
| Rapporto debito/patrimonio netto | 0% |
Come si è comportato PRTA nel lungo periodo?
Vedi performance storica e confrontoAnalisi aziendale e situazione dei dati finanziari
| Dati | Ultimo aggiornamento (ora UTC) |
|---|---|
| Analisi dell'azienda | 2026/07/05 02:07 |
| Prezzo dell'azione a fine giornata | 2026/07/02 00:00 |
| Utili | 2026/03/31 |
| Utili annuali | 2025/12/31 |
Fonti dei dati
I dati utilizzati nella nostra analisi aziendale provengono da S&P Global Market Intelligence LLC. I seguenti dati sono utilizzati nel nostro modello di analisi per generare questo report. I dati sono normalizzati, il che può comportare un ritardo nella disponibilità della fonte.
| Pacchetto | Dati | Tempistica | Esempio Fonte USA * |
|---|---|---|---|
| Dati finanziari della società | 10 anni |
| |
| Stime di consenso degli analisti | +3 anni |
|
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| Prezzi di mercato | 30 anni |
| |
| Proprietà | 10 anni |
| |
| Gestione | 10 anni |
| |
| Sviluppi principali | 10 anni |
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* Esempio per i titoli statunitensi, per i titoli non statunitensi si utilizzano forme e fonti normative equivalenti.
Se non specificato, tutti i dati finanziari si basano su un periodo annuale ma vengono aggiornati trimestralmente. Si tratta dei cosiddetti dati TTM (Trailing Twelve Month) o LTM (Last Twelve Month). Per saperne di più.
Modello di analisi e Snowflake
I dettagli del modello di analisi utilizzato per generare questo report sono disponibili sulla nostra pagina Github; disponiamo inoltre di guide su come utilizzare i nostri report e di tutorial su Youtube.
Scoprite il team di livello mondiale che ha progettato e realizzato il modello di analisi Simply Wall St.
Metriche di settore e industriali
Le nostre metriche di settore e di sezione sono calcolate ogni 6 ore da Simply Wall St; i dettagli del nostro processo sono disponibili su Github.
Fonti analitiche
Prothena Corporation plc è coperta da 24 analisti. 6 di questi analisti ha fornito le stime di fatturato o di utile utilizzate come input per il nostro report. Le stime degli analisti vengono aggiornate nel corso della giornata.
| Analista | Istituzione |
|---|---|
| Geoffrey Meacham | Barclays |
| Tazeen Ahmad | BofA Global Research |
| null null | BTIG |