How Leqembi’s At-Home Injection Launch at Eisai (TSE:4523) Has Changed Its Investment Story

Simply Wall St
  • Earlier this month, Eisai and Biogen announced the U.S. launch of a new subcutaneous maintenance dosing regimen for Leqembi (lecanemab), offering at-home autoinjector treatment for patients with early Alzheimer's disease who have completed initial intravenous therapy.
  • This marks the first anti-amyloid Alzheimer's therapy available as a self-administered at-home injection, with expanded patient education, digital companion tools, and support services aimed at improving access, adherence, and the overall treatment experience.
  • We'll examine how the introduction of an at-home injection option for Leqembi could reshape Eisai's growth outlook and patient reach.

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Eisai Investment Narrative Recap

To be a shareholder in Eisai, you need to believe in the continued expansion and adoption of its Alzheimer's portfolio, especially LEQEMBI, as a driver of revenue and profit growth. The launch of at-home subcutaneous maintenance dosing for LEQEMBI could be a pivotal short-term catalyst, potentially strengthening convenience and adherence, though the overall financial impact depends on uptake and reimbursement clarity; pricing pressure and regulatory risk remain key headwinds to watch.

Of recent announcements, the approval of once-every-four-weeks intravenous maintenance dosing for LEQEMBI in China closely relates to the current U.S. subcutaneous launch, highlighting Eisai’s ongoing push for flexibility and broader access across geographies. Both product updates aim to help position Eisai’s flagship Alzheimer’s therapy competitively and support patient retention against mounting global and regional pricing and reimbursement uncertainties.

However, despite these advances, investors should also be aware that significant regulatory and pricing risks could quickly impact future growth if...

Read the full narrative on Eisai (it's free!)

Eisai's narrative projects ¥897.0 billion revenue and ¥66.6 billion earnings by 2028. This requires 3.8% yearly revenue growth and an increase of ¥16.3 billion in earnings from ¥50.3 billion currently.

Uncover how Eisai's forecasts yield a ¥4988 fair value, a 8% upside to its current price.

Exploring Other Perspectives

TSE:4523 Community Fair Values as at Oct 2025

Retail investors in the Simply Wall St Community assigned Eisai fair values between ¥4,988 and ¥6,744 across two estimates, reflecting diverse outlooks on future earnings potential. However, with intensifying regulatory and pricing risks globally, your view on Eisai’s growth prospects will be shaped by factors beyond recent product launches, explore multiple opinions to challenge your thinking.

Explore 2 other fair value estimates on Eisai - why the stock might be worth as much as 46% more than the current price!

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

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