Spero Therapeutics Past Earnings Performance
Past criteria checks 4/6
Spero Therapeutics has been growing earnings at an average annual rate of 34.9%, while the Biotechs industry saw earnings growing at 36.2% annually. Revenues have been growing at an average rate of 24.3% per year. Spero Therapeutics's return on equity is 28.8%, and it has net margins of 24.9%.
Key information
34.93%
Earnings growth rate
48.65%
EPS growth rate
| Biotechs Industry Growth | 17.04% |
| Revenue growth rate | 24.30% |
| Return on equity | 28.78% |
| Net Margin | 24.90% |
| Last Earnings Update | 31 Mar 2026 |
Recent past performance updates
Recent updates
Spero Therapeutics: Yesterday's Selloff On Utebzi Approval Seems Bewildering
Summary Spero Therapeutics, Inc. and partner GSK receive FDA approval for Utebzi, the first oral carbapenem for complicated urinary tract infections, via partnership with GSK. SPRO stands to receive milestone payments and royalties from GSK, with potential annual earnings of ~$50m and upside if Utebzi achieves blockbuster status. Despite a volatile share price and limited pipeline, SPRO's low burn rate and funding runway into 2028 support a 'buy the dip' thesis for risk-tolerant investors. I initiate SPRO with a Buy rating, viewing the stock as undervalued relative to its prospective revenue streams, but highlight the high-risk, lumpy nature of the opportunity. Read the full article on Seeking AlphaSpero Therapeutics, Inc. (NASDAQ:SPRO) Held Back By Insufficient Growth Even After Shares Climb 26%
Spero Therapeutics, Inc. ( NASDAQ:SPRO ) shareholders would be excited to see that the share price has had a great...
Positive Phase III Efficacy Will Unlock Expanded Antibiotic Markets
The downward revision in Spero Therapeutics’ consensus price target largely reflects declines in its future P/E multiple and net profit margin, resulting in a lower fair value estimate of $4.00. What's in the News The phase III PIVOT-PO trial of tebipenem HBr, an investigational oral treatment for complicated urinary tract infections (cUTIs), was stopped early due to efficacy, following an Independent Data Monitoring Committee recommendation.Is Spero Therapeutics (NASDAQ:SPRO) In A Good Position To Deliver On Growth Plans?
NasdaqGS:SPRO 1 Year Share Price vs Fair Value Explore Spero Therapeutics's Fair Values from the Community and select...Insufficient Growth At Spero Therapeutics, Inc. (NASDAQ:SPRO) Hampers Share Price
With a price-to-sales (or "P/S") ratio of 3.1x Spero Therapeutics, Inc. ( NASDAQ:SPRO ) may be sending very bullish...
Successful Phase III Trial Will Redefine Treatment For Complicated UTIs
Successful PIVOT-PO trial and regulatory approval could propel revenue growth, leveraging a strategic partnership with GSK for commercialization.Spero Therapeutics, Inc. (NASDAQ:SPRO) Looks Inexpensive After Falling 27% But Perhaps Not Attractive Enough
To the annoyance of some shareholders, Spero Therapeutics, Inc. ( NASDAQ:SPRO ) shares are down a considerable 27% in...Spero Therapeutics: Undervalued Based On Just Tebipenem And GSK Deal
Summary Spero Therapeutics' tebipenem, an oral carbapenem for cUTIs, has high approval potential, supported by a successful phase 3 trial and a GSK licensing deal. The need for oral carbapenems is critical due to rising resistance to current oral treatments for complicated urinary tract infections. Tebipenem's success in the confirmatory phase 3 trial is highly probable, given its prior phase 3 success and publication in NEJM. Despite risks, SPRO's valuation is attractive, with significant upside potential from tebipenem milestones and possible pipeline progress. Read the full article on Seeking AlphaThere Is A Reason Spero Therapeutics, Inc.'s (NASDAQ:SPRO) Price Is Undemanding
Spero Therapeutics, Inc.'s ( NASDAQ:SPRO ) price-to-sales (or "P/S") ratio of 0.5x might make it look like a strong buy...Insufficient Growth At Spero Therapeutics, Inc. (NASDAQ:SPRO) Hampers Share Price
Spero Therapeutics, Inc.'s ( NASDAQ:SPRO ) price-to-sales (or "P/S") ratio of 0.7x might make it look like a strong buy...Spero Therapeutics Delivers On Game Plan To Create Shareholder Value
Summary Spero Therapeutics, Inc. has continued to build and advance its pipeline over the past several months and is now on the verge of generating landmark data with multi-bagger potential. Spero has excellent downside protection and additional upside from the payments from the Tebipenem HBr deal with GSK. Spero's significant undervaluation and potential path forward are highlighted in the peer comparison. Read the full article on Seeking AlphaSpero Therapeutics, Inc. (NASDAQ:SPRO) Held Back By Insufficient Growth Even After Shares Climb 27%
Spero Therapeutics, Inc. ( NASDAQ:SPRO ) shares have continued their recent momentum with a 27% gain in the last month...Spero Therapeutics, Inc.'s (NASDAQ:SPRO) Share Price Boosted 26% But Its Business Prospects Need A Lift Too
The Spero Therapeutics, Inc. ( NASDAQ:SPRO ) share price has done very well over the last month, posting an excellent...Need To Know: Analysts Just Made A Substantial Cut To Their Spero Therapeutics, Inc. (NASDAQ:SPRO) Estimates
Today is shaping up negative for Spero Therapeutics, Inc. ( NASDAQ:SPRO ) shareholders, with the analysts delivering a...Spero Therapeutics, Inc. (NASDAQ:SPRO) Shares Fly 26% But Investors Aren't Buying For Growth
Those holding Spero Therapeutics, Inc. ( NASDAQ:SPRO ) shares would be relieved that the share price has rebounded 26...Industry Analysts Just Upgraded Their Spero Therapeutics, Inc. (NASDAQ:SPRO) Revenue Forecasts By 40%
Spero Therapeutics, Inc. ( NASDAQ:SPRO ) shareholders will have a reason to smile today, with the analysts making...Revenue & Expenses Breakdown
How Spero Therapeutics makes and spends money. Based on latest reported earnings, on an LTM basis.
Earnings and Revenue History
| Date | Revenue | Earnings | G+A Expenses | R&D Expenses |
|---|---|---|---|---|
| 31 Mar 26 | 61 | 15 | 19 | 0 |
| 31 Dec 25 | 67 | 9 | 21 | 0 |
| 30 Sep 25 | 41 | -44 | 24 | 0 |
| 30 Jun 25 | 49 | -54 | 25 | 0 |
| 31 Mar 25 | 45 | -70 | 25 | 0 |
| 31 Dec 24 | 48 | -69 | 24 | 0 |
| 30 Sep 24 | 106 | 4 | 23 | -33 |
| 30 Jun 24 | 118 | 17 | 24 | 0 |
| 31 Mar 24 | 111 | 23 | 24 | 0 |
| 31 Dec 23 | 104 | 23 | 26 | 0 |
| 30 Sep 23 | 78 | -2 | 26 | 33 |
| 30 Jun 23 | 54 | -10 | 27 | 0 |
| 31 Mar 23 | 54 | -27 | 28 | 0 |
| 31 Dec 22 | 54 | -46 | 36 | 0 |
| 30 Sep 22 | 9 | -102 | 43 | 0 |
| 30 Jun 22 | 10 | -113 | 48 | 0 |
| 31 Mar 22 | 13 | -103 | 49 | 0 |
| 31 Dec 21 | 18 | -90 | 42 | 0 |
| 30 Sep 21 | 17 | -79 | 36 | 0 |
| 30 Jun 21 | 18 | -76 | 30 | 0 |
| 31 Mar 21 | 15 | -74 | 26 | 0 |
| 31 Dec 20 | 9 | -79 | 21 | 0 |
| 30 Sep 20 | 11 | -85 | 18 | 0 |
| 30 Jun 20 | 12 | -84 | 17 | 0 |
| 31 Mar 20 | 12 | -80 | 16 | 0 |
| 31 Dec 19 | 18 | -61 | 16 | 0 |
| 30 Sep 19 | 16 | -47 | 15 | 0 |
| 30 Jun 19 | 12 | -39 | 14 | 0 |
| 31 Mar 19 | 11 | -36 | 14 | 0 |
| 31 Dec 18 | 4 | -42 | 13 | 0 |
| 30 Sep 18 | 3 | -46 | 12 | 0 |
| 30 Jun 18 | 3 | -47 | 12 | 0 |
| 31 Mar 18 | 3 | -50 | 12 | 0 |
| 31 Dec 17 | 2 | -46 | 11 | 0 |
| 30 Sep 17 | 1 | -40 | 11 | 0 |
| 30 Jun 17 | 1 | -35 | 9 | 0 |
| 31 Mar 17 | 0 | -30 | 7 | 0 |
| 31 Dec 16 | 0 | -30 | 7 | 0 |
Quality Earnings: SPRO has high quality earnings.
Growing Profit Margin: SPRO became profitable in the past.
Free Cash Flow vs Earnings Analysis
Past Earnings Growth Analysis
Earnings Trend: SPRO has become profitable over the past 5 years, growing earnings by 34.9% per year.
Accelerating Growth: SPRO has become profitable in the last year, making the earnings growth rate difficult to compare to its 5-year average.
Earnings vs Industry: SPRO has become profitable in the last year, making it difficult to compare its past year earnings growth to the Biotechs industry (54.5%).
Return on Equity
High ROE: SPRO's Return on Equity (28.8%) is considered high.
Return on Assets
Return on Capital Employed
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Company Analysis and Financial Data Status
| Data | Last Updated (UTC time) |
|---|---|
| Company Analysis | 2026/07/05 03:20 |
| End of Day Share Price | 2026/07/02 00:00 |
| Earnings | 2026/03/31 |
| Annual Earnings | 2025/12/31 |
Data Sources
The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.
| Package | Data | Timeframe | Example US Source * |
|---|---|---|---|
| Company Financials | 10 years |
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| Analyst Consensus Estimates | +3 years |
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| Market Prices | 30 years |
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| Ownership | 10 years |
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| Management | 10 years |
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| Key Developments | 10 years |
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* Example for US securities, for non-US equivalent regulatory forms and sources are used.
Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.
Analysis Model and Snowflake
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Industry and Sector Metrics
Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.
Analyst Sources
Spero Therapeutics, Inc. is covered by 6 analysts. 0 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.
| Analyst | Institution |
|---|---|
| Esther Lannie Hong | Berenberg |
| Jason Matthew Gerberry | BofA Global Research |
| Esther Lannie Hong | Brean Capital Historical (Janney Montgomery) |