Spero Therapeutics, Inc.

NasdaqGS:SPRO Stock Report

Market Cap: US$134.7m

Spero Therapeutics Ownership

Who are the major shareholders and have insiders been buying or selling?

Recent Insider Transactions

NasdaqGS:SPRO Recent Insider Transactions by Companies or Individuals
DateValueNameEntityRoleSharesMax Price
06 Feb 26SellUS$44,019Timothy KeutzerIndividual18,652US$2.36
06 Feb 26SellUS$207,484Esther RajaveluIndividual87,917US$2.36
04 Feb 26SellUS$101,175Timothy KeutzerIndividual46,586US$2.24
02 Feb 26SellUS$40,572Esther RajaveluIndividual18,442US$2.20
07 Nov 25SellUS$95,440Esther RajaveluIndividual40,270US$2.37
28 Aug 25SellUS$3,339Timothy KeutzerIndividual1,695US$1.97
28 Aug 25SellUS$12,947Ankit MahadeviaIndividual6,572US$1.97

Insider Trading Volume

Insider Buying: SPRO insiders have only sold shares in the past 3 months.

Ownership Breakdown

What is the ownership structure of SPRO?
Owner TypeNumber of SharesOwnership Percentage
Individual Insiders1,370,2062.43%
Public Companies9,190,60616.3%
VC/PE Firms9,190,60616.3%
Institutions11,618,47120.6%
General Public24,969,40644.3%

Dilution of Shares: Shareholders have not been meaningfully diluted in the past year.

Top Shareholders

Top 25 shareholders own 53.9% of the company
OwnershipNameSharesCurrent ValueChange %Portfolio %
16.3%
GSK plc
9,190,606US$22.0m375%0.43%
16.3%
SR One Capital Management, LP
9,190,606US$22.0m0%2.68%
4.19%
Pfizer Venture Investments LLC
2,362,348US$5.6m0%1.9%
3.7%
The Vanguard Group, Inc.
2,083,462US$5.0m4.7%no data
2.85%
Anson Group
1,603,569US$3.8m0%0.45%
2.27%
Renaissance Technologies LLC
1,279,522US$3.1m-11.9%no data
1.58%
GV Management Company, LLC
889,979US$2.1m0%0.32%
0.94%
Geode Capital Management, LLC
529,195US$1.3m0.33%no data
0.77%
BlackRock, Inc.
433,616US$1.0m-0.26%no data
0.68%
Ankit Mahadevia
383,795US$917.3k0%no data
0.51%
Timothy Keutzer
288,547US$689.6k90.7%no data
0.39%
The Informed Momentum Company LLC
218,084US$521.2k-22.8%0.05%
0.37%
State Street Global Advisors, Inc.
210,151US$502.3k10.1%no data
0.37%
Ionic Capital Management LLC
208,725US$498.9k0%0.57%
0.32%
GSA Capital Partners LLP
178,930US$427.6k67.4%0.04%
0.3%
Esther Rajavelu
168,554US$402.8k115%no data
0.28%
Jane Street Group, LLC
158,344US$378.4k268%no data
0.23%
SEI Investments Company
132,010US$315.5k0%no data
0.23%
OMERS Administration Corporation
131,127US$313.4k0%no data
0.23%
Northern Trust Global Investments
129,643US$309.8k0%no data
0.23%
Satyavrat Shukla
127,856US$305.6k0%no data
0.21%
Squarepoint OPS LLC
119,434US$285.4k0%no data
0.21%
UBS Asset Management AG
116,447US$278.3k330%no data
0.21%
ADAR1 Capital Management, LLC
115,539US$276.1k0%0.03%
0.2%
Bridgeway Capital Management, LLC
114,800US$274.4k0%no data

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/02/17 10:33
End of Day Share Price 2026/02/13 00:00
Earnings2025/09/30
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Spero Therapeutics, Inc. is covered by 6 analysts. 0 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Esther Lannie HongBerenberg
Jason Matthew GerberryBofA Global Research
Esther Lannie HongBrean Capital (formerly Janney Montgomery)