uniQure (QURE): Examining Valuation Following Positive Huntington’s Disease Gene Therapy Results

uniQure (NasdaqGS:QURE) is attracting attention after reporting positive Phase I/II trial results for its Huntington’s disease gene therapy candidate, AMT-130. The data showed a significant slowing in disease progression.

See our latest analysis for uniQure.

uniQure’s story has quickly shifted from steady to headline-grabbing, thanks to the promising AMT-130 update. The stock’s recent 30-day share price return of 252.15% and a remarkable 1-year total shareholder return nearing 990% show momentum has exploded, with investors evidently repositioning after positive clinical news and recent conference buzz. While comments around insider selling have kept some on the sidelines, the long-term performance is a testament to renewed optimism and outweighs short-term jitters.

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With the stock surging nearly tenfold over the past year, investors now face a critical question: is uniQure still undervalued after its clinical breakthrough, or has the market already priced in future growth expectations?

Most Popular Narrative: 7% Undervalued

According to the most influential narrative, uniQure’s estimated fair value stands at $66.50, noticeably higher than the latest close around $61.56 per share. This sets the stage for conflicting expectations about just how far the recent rally can go if business catalysts materialize.

The newly reported topline Phase 1/2 data are widely seen as a game-changer, with clear evidence that AMT-130 meaningfully impacts Huntington's progression across several functional and cognitive measures. This reduces regulatory risk and bolsters the outlook for accelerated approval.

Read the complete narrative.

Curious how those approval hopes power such an aggressive fair value? Find out which blockbuster revenue forecasts and profit multiples this narrative is baking in. There is more to the calculation than you might expect.

Result: Fair Value of $66.50 (UNDERVALUED)

Have a read of the narrative in full and understand what's behind the forecasts.

However, challenges remain, such as regulatory uncertainties for AMT-130 and recent shortfalls in revenue. Either of these issues could quickly dampen future expectations.

Find out about the key risks to this uniQure narrative.

Build Your Own uniQure Narrative

If you want to dig deeper or challenge the consensus, you can quickly build your own perspective based on the numbers in just a few minutes. Do it your way

A great starting point for your uniQure research is our analysis highlighting 2 key rewards and 3 important warning signs that could impact your investment decision.

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

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