Stock Analysis

Novavax (NVAX) Is Up 14.5% After Sanofi Expands Use of Matrix-M Adjuvant Technology - What's Changed

  • Sanofi recently announced an expanded agreement with Novavax, granting broader rights to use Novavax’s Matrix-M adjuvant in the early-stage development of its pandemic influenza vaccine candidates, supported by U.S. government funding.
  • This collaboration may position Novavax for new milestone payments and future royalties, highlighting increased adoption of its vaccine technology by a major pharmaceutical partner.
  • We'll look at how Sanofi’s increased adoption of Matrix-M technology could impact Novavax's long-term revenue prospects and risk profile.

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Novavax Investment Narrative Recap

For investors considering Novavax, the central premise is that broad adoption of its Matrix-M platform by established partners such as Sanofi can help the company offset dependence on legacy COVID-19 vaccine revenues. The recent expansion of the Sanofi agreement reinforces demand for Novavax technology and may introduce new revenue streams through milestone and royalty payments, but it does not fundamentally shift the immediate catalysts or primary risk; Novavax remains reliant on the pace and success of partner-driven commercialization and milestone recognition.

The most relevant recent announcement is the milestone payment triggered by Takeda's regulatory approval of Nuvaxovid for the Omicron variant, reflecting Novavax’s ongoing execution on partnership milestones. This kind of news complements the Sanofi expansion by supporting near-term revenues and highlighting how Novavax’s strategy hinges on successful external commercialization efforts and regulatory progress.

However, in contrast, investors should be mindful that milestone payments are contingent on partner commercialization timelines, which…

Read the full narrative on Novavax (it's free!)

Novavax's narrative projects $348.5 million in revenue and $55.9 million in earnings by 2028. This requires a 31.4% annual revenue decline and a $366.9 million decrease in earnings from $422.8 million today.

Uncover how Novavax's forecasts yield a $12.50 fair value, a 31% upside to its current price.

Exploring Other Perspectives

NVAX Community Fair Values as at Oct 2025
NVAX Community Fair Values as at Oct 2025

Community valuations for Novavax range widely, from US$2.48 to US$220, across 13 individual Simply Wall St Community submissions. Revenue timing risk tied to partner milestones continues to shape the outlook for future performance, consider the range of views and explore more perspectives for a fuller picture.

Explore 13 other fair value estimates on Novavax - why the stock might be a potential multi-bagger!

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

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