Lyell Immunopharma, Inc.

NasdaqGS:LYEL Stock Report

Market Cap: US$486.5m

Lyell Immunopharma Future Growth

Future criteria checks 2/6

Lyell Immunopharma is forecast to grow earnings and revenue by 0.3% and 66.8% per annum respectively while EPS is expected to grow by 28.3% per annum.

Key information

0.3%

Earnings growth rate

28.31%

EPS growth rate

Biotechs earnings growth24.7%
Revenue growth rate66.8%
Future return on equityn/a
Analyst coverage

Good

Last updated07 May 2026

Recent future growth updates

Recent updates

Seeking Alpha Apr 16

A First Look At Lyell Immunopharma

Summary Lyell Immunopharma offers potential upside with lead CAR T candidate ronde-cel for 3L+ relapsed-refractory large B-cell lymphoma, showing strong efficacy and safety. Ronde-cel's registrational trial targets impressive potential results, with pivotal data expected mid-2027 and BLA submission in 2H27. LYL273, recently in-licensed for metastatic colorectal cancer, demonstrated a 67% ORR and 8-month mPFS at dose level 2; pivotal trial initiation is planned for 1H27. Despite a $300 million premium to cash and a history of clinical failures, LYEL is a high-risk, high-reward play best suited for aggressive, risk-tolerant investors. Read the full article on Seeking Alpha
Seeking Alpha Oct 25

Lyell Immunopharma: Oversold And Poised For A Turning Point To Growth

Summary Lyell Immunopharma, Inc.'s financials show reduced losses and efficient cash management, with a strong cash position supporting operations through 2027 despite a challenging biotech environment. The company's innovative CAR T-cell therapies, particularly LYL119 and IMPT-314, target critical oncology challenges with promising early clinical results expected by late 2025. Lyell's acquisition of ImmPACT Bio expands its pipeline into hematologic cancers, enhancing its portfolio with dual-targeting CAR T-cell therapies and broadening therapeutic options. Despite market skepticism and high-risk nature, Lyell's undervalued assets and strategic focus on T-cell reprogramming and operational efficiency position it for long-term success. Read the full article on Seeking Alpha
Seeking Alpha Apr 16

Lyell Immunopharma: Testing The T-Cell Thesis With 2 Upcoming Data Catalysts

Summary Lyell Immunopharma, Inc.'s stock price has risen over 20% YTD and over 45% in the past 12 months. The company focuses on T-cell therapies for solid tumors and has two clinical-stage assets. Lyell has upcoming data catalysts, with Phase 1 results expected in the first half of 2024 and the second half of this year. The two programs in question involve a CAR-T cell therapy targeting breast and lung cancer and a TIL therapy targeting melanoma, lung, and colorectal cancer. Lyell has funding to last until 2027 and a review of its approach to designing cell therapies gives me some optimism upcoming data readouts can be positive - there is substantial risk to this thesis; however, that must be acknowledged. Read the full article on Seeking Alpha
Analysis Article Feb 23

Companies Like Lyell Immunopharma (NASDAQ:LYEL) Are In A Position To Invest In Growth

We can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...
Analysis Article Nov 09

Companies Like Lyell Immunopharma (NASDAQ:LYEL) Are In A Position To Invest In Growth

We can readily understand why investors are attracted to unprofitable companies. For example, although Amazon.com made...
Analysis Article Aug 29

Analysts' Revenue Estimates For Lyell Immunopharma, Inc. (NASDAQ:LYEL) Are Surging Higher

Lyell Immunopharma, Inc. ( NASDAQ:LYEL ) shareholders will have a reason to smile today, with the analysts making...
Analysis Article Aug 11

We Think Lyell Immunopharma (NASDAQ:LYEL) Can Afford To Drive Business Growth

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Analysis Article Dec 15

Lyell Immunopharma (NASDAQ:LYEL) Is In A Good Position To Deliver On Growth Plans

Even when a business is losing money, it's possible for shareholders to make money if they buy a good business at the...
Seeking Alpha Oct 06

Lyell Immunopharma gets FDA nod to start phase 1 trial of its cancer therapy LYL845

Lyell Immunopharma (NASDAQ:LYEL) on Thursday said the U.S. FDA had cleared its investigational new drug application to start a phase 1 trial for its experimental cancer therapy LYL845. LYEL stock +4.1% to $8.42 after hours. LYL485 is a tumor infiltrating lymphocyte enhanced with LYEL's reprogramming technology. The early-stage trial will evaluate LYL485 as a treatment for melanoma, the most serious type of skin cancer, LYEL said in a statement. The trial will also have expansion cohorts for patients with non-small cell lung cancer and colorectal cancer. Initial data presentation from the trial is expected in 2024.
Analysis Article Sep 12

Companies Like Lyell Immunopharma (NASDAQ:LYEL) Are In A Position To Invest In Growth

We can readily understand why investors are attracted to unprofitable companies. For example, biotech and mining...
Analysis Article Aug 08

News Flash: Analysts Just Made A Huge Upgrade To Their Lyell Immunopharma, Inc. (NASDAQ:LYEL) Forecasts

Lyell Immunopharma, Inc. ( NASDAQ:LYEL ) shareholders will have a reason to smile today, with the analysts making...

Earnings and Revenue Growth Forecasts

NasdaqGS:LYEL - Analysts future estimates and past financials data (USD Millions)
DateRevenueEarningsFree Cash FlowCash from OpAvg. No. Analysts
12/31/202837-276-82N/A3
12/31/20272-251-71N/A5
12/31/20260-190-61N/A6
3/31/20260-246-134-134N/A
12/31/20250-274-151-150N/A
9/30/20250-326-166-165N/A
6/30/20250-331-172-171N/A
3/31/20250-335-176-175N/A
12/31/20240-343-163-162N/A
9/30/20240-204-156-156N/A
6/30/20240-210-159-158N/A
3/31/20240-228-161-159N/A
12/31/20230-235-166-164N/A
9/30/202349-190-171-163N/A
6/30/202348-209-173-163N/A
3/31/202384-182-184-168N/A
12/31/202285-183-194-170N/A
9/30/202239-258-192-163N/A
6/30/202242-237-190-151N/A
3/31/20229-263-197-141N/A
12/31/202111-250-192-126N/A
9/30/202110-205-200-120N/A
6/30/20218-192-197-116N/A
3/31/20219-230-235-171N/A
12/31/20208-208-212-161N/A
12/31/20191-131N/A39N/A

Analyst Future Growth Forecasts

Earnings vs Savings Rate: LYEL is forecast to remain unprofitable over the next 3 years.

Earnings vs Market: LYEL is forecast to remain unprofitable over the next 3 years.

High Growth Earnings: LYEL is forecast to remain unprofitable over the next 3 years.

Revenue vs Market: LYEL's revenue (66.8% per year) is forecast to grow faster than the US market (11.4% per year).

High Growth Revenue: LYEL's revenue (66.8% per year) is forecast to grow faster than 20% per year.


Earnings per Share Growth Forecasts


Future Return on Equity

Future ROE: Insufficient data to determine if LYEL's Return on Equity is forecast to be high in 3 years time


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/07 21:58
End of Day Share Price 2026/05/07 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

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Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Lyell Immunopharma, Inc. is covered by 7 analysts. 6 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Jack AllenBaird
Jason ZemanskyBofA Global Research
Reni BenjaminCitizens JMP Securities, LLC