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Zevra Therapeutics, Inc.NasdaqGS:ZVRA Stock Report

Market Cap US$594.1m
Share Price
US$10.61
US$26
59.2% undervalued intrinsic discount
1Y43.4%
7D7.2%
Portfolio Value
View

Zevra Therapeutics, Inc.

NasdaqGS:ZVRA Stock Report

Market Cap: US$594.1m

Zevra Therapeutics (ZVRA) Stock Overview

A commercial-stage company, focuses on addressing unmet needs for the treatment of rare diseases in the United States. More details

ZVRA fundamental analysis
Snowflake Score
Valuation5/6
Future Growth6/6
Past Performance3/6
Financial Health4/6
Dividends0/6

ZVRA Community Fair Values

Create Narrative

See what 56 others think this stock is worth. Follow their fair value or set your own to get alerts.

Zevra Therapeutics, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Zevra Therapeutics
Historical stock prices
Current Share PriceUS$10.61
52 Week HighUS$13.16
52 Week LowUS$7.16
Beta0.88
1 Month Change12.87%
3 Month Change18.68%
1 Year Change43.38%
3 Year Change139.50%
5 Year Change21.53%
Change since IPO-94.08%

Recent News & Updates

ZVRA: NPC Diagnosis Expansion And EU Decision Will Drive Future Upside Potential

Narrative Update: Zevra Therapeutics The updated analyst price target for Zevra Therapeutics is now $23, a $1 increase, as analysts point to the launch progress of Miplyffa, expectations for continued U.S. market penetration, and potential future catalysts including EU approval, patent term extension, and celiprolol development in VEDS. Analyst Commentary Bullish analysts are highlighting Zevra Therapeutics as a name where current valuation is closely linked to the rollout of Miplyffa and a set of identifiable potential catalysts.

ZVRA: NPC Diagnosis Expansion Will Drive Future Upside Potential

Analysts have maintained Zevra Therapeutics' fair value estimate at $26.00, with slight tweaks to growth, margin, and future P/E assumptions. Recent Street research highlights a $23 price target, supported by views that current pricing reflects conservative Miplyffa adoption and potential upside from broader patient reach and future regulatory or pipeline milestones.

ZVRA: Expanding NPC Diagnosis And EU Decision Will Drive Future Upside

Analysts have kept Zevra Therapeutics' fair value estimate steady at $26.00 while updating their assumptions on Miplyffa's launch trajectory and potential upside from EU approval, expanded U.S. adoption, and celiprolol optionality, which they note is reflected in Street price targets moving toward $23.00. Analyst Commentary Bullish analysts are framing Zevra's current share price as tied closely to conservative expectations for Miplyffa, largely anchored to the already diagnosed U.S. Niemann Pick type C population.

Recent updates

ZVRA: NPC Diagnosis Expansion And EU Decision Will Drive Future Upside Potential

Narrative Update: Zevra Therapeutics The updated analyst price target for Zevra Therapeutics is now $23, a $1 increase, as analysts point to the launch progress of Miplyffa, expectations for continued U.S. market penetration, and potential future catalysts including EU approval, patent term extension, and celiprolol development in VEDS. Analyst Commentary Bullish analysts are highlighting Zevra Therapeutics as a name where current valuation is closely linked to the rollout of Miplyffa and a set of identifiable potential catalysts.

ZVRA: NPC Diagnosis Expansion Will Drive Future Upside Potential

Analysts have maintained Zevra Therapeutics' fair value estimate at $26.00, with slight tweaks to growth, margin, and future P/E assumptions. Recent Street research highlights a $23 price target, supported by views that current pricing reflects conservative Miplyffa adoption and potential upside from broader patient reach and future regulatory or pipeline milestones.

ZVRA: Expanding NPC Diagnosis And EU Decision Will Drive Future Upside

Analysts have kept Zevra Therapeutics' fair value estimate steady at $26.00 while updating their assumptions on Miplyffa's launch trajectory and potential upside from EU approval, expanded U.S. adoption, and celiprolol optionality, which they note is reflected in Street price targets moving toward $23.00. Analyst Commentary Bullish analysts are framing Zevra's current share price as tied closely to conservative expectations for Miplyffa, largely anchored to the already diagnosed U.S. Niemann Pick type C population.

Zevra Therapeutics: Miplyffa Uptake Validates Rare Disease Commercial Model

Mar 10

ZVRA: Growing NPC Access And Data Will Support Long-Term Rare Disease Upside

Analysts have maintained their $26.00 price target for Zevra Therapeutics, citing updated assumptions that reflect slightly different estimates for revenue growth, profit margins, and future P/E, without materially changing their overall view of the stock's valuation. What's in the News Zevra Therapeutics appointed Justin Renz as Chief Financial Officer, effective March 9, 2026.

ZVRA: Expanded Access And NPC Data Will Support Long-Term Rare Disease Upside

Analysts have kept their Zevra Therapeutics price target steady at $26.00. This points to largely unchanged fair value assumptions, even as they refine inputs such as revenue growth, profit margins and future P/E expectations.

ZVRA: Expanded Access And NPC Data Will Support Long-Term Rare Disease Upside

Analysts have maintained their price target on Zevra Therapeutics at $26.00, citing only modest tweaks to assumptions around revenue growth, profit margins, the discount rate, and future P/E that did not materially change their overall view. What's in the News Zevra presented four posters at the 22nd Annual WORLDSymposium highlighting new data on MIPLYFFA (arimoclomol) for Niemann Pick Disease Type C.

ZVRA: Expanded Access Deal Will Support Long-Term Rare Disease Upside

Narrative Update: Zevra Therapeutics Analyst Price Target The analyst price target for Zevra Therapeutics is now set at US$26.00. Analysts cite small adjustments to revenue growth assumptions, profit margin expectations, and future P/E estimates as key drivers for the updated view.

ZVRA: Expanded Rare Disease Access Agreement Will Support Long-Term Upside

Analysts have maintained their price target for Zevra Therapeutics at US$26.00, citing only modest adjustments to assumptions around revenue growth, profit margins and future P/E. Taken together, these changes do not alter their overall view of the company’s valuation.

ZVRA: Future Rare Disease Portfolio Will Support Long-Term Upside

Analysts have modestly increased their price target on Zevra Therapeutics to $26.00 per share, citing slightly stronger long term revenue growth and profit margin assumptions, alongside a marginally lower projected future price to earnings multiple. What's in the News Chief Financial Officer and Treasurer R.

ZVRA: Future Rare Disease Approvals Will Drive Long-Term Upside

Analysts have reduced their price target on Zevra Therapeutics by 3.00 dollars to 26.00 dollars, citing expectations for slower revenue growth, slightly lower profit margins, and a modestly higher discount rate, partially offset by a lower anticipated future price to earnings multiple. What's in the News Chief Financial Officer and Treasurer R.

Zevra Therapeutics, Inc. (NASDAQ:ZVRA) Just Reported And Analysts Have Been Cutting Their Estimates

Nov 08
Zevra Therapeutics, Inc. (NASDAQ:ZVRA) Just Reported And Analysts Have Been Cutting Their Estimates

Zevra Therapeutics (NASDAQ:ZVRA) Is Using Debt Safely

Nov 03
Zevra Therapeutics (NASDAQ:ZVRA) Is Using Debt Safely

What You Can Learn From Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) P/S After Its 26% Share Price Crash

Sep 08
What You Can Learn From Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) P/S After Its 26% Share Price Crash

Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) 26% Jump Shows Its Popularity With Investors

Jul 10
Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) 26% Jump Shows Its Popularity With Investors

Revenues Tell The Story For Zevra Therapeutics, Inc. (NASDAQ:ZVRA) As Its Stock Soars 26%

May 22
Revenues Tell The Story For Zevra Therapeutics, Inc. (NASDAQ:ZVRA) As Its Stock Soars 26%
User avatar

MIPLYFFA Launch Will Spark European Expansion In 2025

Successful MIPLYFFA launch and European expansion plans indicate potential revenue growth and stable streams through strong demand and patient engagement.

Investors Appear Satisfied With Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) Prospects

Mar 10
Investors Appear Satisfied With Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) Prospects

Here's What Analysts Are Forecasting For Zevra Therapeutics, Inc. (NASDAQ:ZVRA) After Its Third-Quarter Results

Nov 15
Here's What Analysts Are Forecasting For Zevra Therapeutics, Inc. (NASDAQ:ZVRA) After Its Third-Quarter Results

Investors Appear Satisfied With Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) Prospects As Shares Rocket 34%

Aug 30
Investors Appear Satisfied With Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) Prospects As Shares Rocket 34%

Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) 26% Jump Shows Its Popularity With Investors

Jul 12
Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) 26% Jump Shows Its Popularity With Investors

Analysts Just Shaved Their Zevra Therapeutics, Inc. (NASDAQ:ZVRA) Forecasts Dramatically

Apr 07
Analysts Just Shaved Their Zevra Therapeutics, Inc. (NASDAQ:ZVRA) Forecasts Dramatically

Zevra Therapeutics, Inc. (NASDAQ:ZVRA) Just Reported And Analysts Have Been Cutting Their Estimates

Apr 04
Zevra Therapeutics, Inc. (NASDAQ:ZVRA) Just Reported And Analysts Have Been Cutting Their Estimates

Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) Stock Retreats 27% But Revenues Haven't Escaped The Attention Of Investors

Apr 02
Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) Stock Retreats 27% But Revenues Haven't Escaped The Attention Of Investors

Investors Appear Satisfied With Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) Prospects

Dec 28
Investors Appear Satisfied With Zevra Therapeutics, Inc.'s (NASDAQ:ZVRA) Prospects

Shareholder Returns

ZVRAUS PharmaceuticalsUS Market
7D7.2%5.1%1.8%
1Y43.4%34.5%29.8%

Return vs Industry: ZVRA exceeded the US Pharmaceuticals industry which returned 34.5% over the past year.

Return vs Market: ZVRA exceeded the US Market which returned 29.8% over the past year.

Price Volatility

Is ZVRA's price volatile compared to industry and market?
ZVRA volatility
ZVRA Average Weekly Movement8.2%
Pharmaceuticals Industry Average Movement9.7%
Market Average Movement7.1%
10% most volatile stocks in US Market16.1%
10% least volatile stocks in US Market3.2%

Stable Share Price: ZVRA has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: ZVRA's weekly volatility (8%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
200661Neil McFarlanewww.zevra.com

Zevra Therapeutics, Inc., a commercial-stage company, focuses on addressing unmet needs for the treatment of rare diseases in the United States. The company develops its products through Ligand Activated Technology platform. Its lead product candidate is KP1077, consisting of KP1077IH, which is under Phase 3 clinical trial for the treatment of idiopathic hypersomnia, and KP1077N, which is under Phase 3 clinical trial to treat narcolepsy.

Zevra Therapeutics, Inc. Fundamentals Summary

How do Zevra Therapeutics's earnings and revenue compare to its market cap?
ZVRA fundamental statistics
Market capUS$594.10m
Earnings (TTM)US$77.59m
Revenue (TTM)US$106.47m
8.1x
P/E Ratio
5.9x
P/S Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
ZVRA income statement (TTM)
RevenueUS$106.47m
Cost of RevenueUS$16.48m
Gross ProfitUS$89.99m
Other ExpensesUS$12.40m
EarningsUS$77.59m

Last Reported Earnings

Dec 31, 2025

Next Earnings Date

May 06, 2026

Earnings per share (EPS)1.31
Gross Margin84.52%
Net Profit Margin72.87%
Debt/Equity Ratio40.0%

How did ZVRA perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/05 10:35
End of Day Share Price 2026/05/05 00:00
Earnings2025/12/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Zevra Therapeutics, Inc. is covered by 16 analysts. 9 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Kenneth TrbovichBrean Capital Historical (Janney Montgomery)
Kambiz YazdiBTIG
Sumant Satchidanand KulkarniCanaccord Genuity