Stock Analysis

Assessing Gossamer Bio (GOSS) Valuation After FDA Progress and Pulmonary Hypertension Pipeline Advances

Gossamer Bio (GOSS) has caught the market’s eye this month, and for good reason. The company’s shares have been trading higher in response to encouraging FDA designations for its experimental drug seralutinib, targeting pulmonary arterial hypertension (PAH) and pulmonary hypertension associated with interstitial lung disease (PH-ILD). Along with a strong presence at recent investor conferences, Gossamer Bio appears determined to cement its position in these specialized lung disease markets. Investors are watching closely, wondering how these scientific milestones might translate into long-term value. Broadly, Gossamer Bio’s stock has seen significant momentum. The share price has leapt over 75% in the past month, nearly doubling year-to-date, and delivering a strong 276% return over the past year. This surge comes after a difficult multi-year stretch, as the company worked to advance its pipeline and refocus on core opportunities. Recent developments signal that market sentiment is shifting, as investors begin to price in the potential for transformative growth if regulatory and clinical goals are met. With all this in play, the big question for investors is simple: after this year’s surge, is Gossamer Bio now undervalued with further room to run, or is the market already factoring in most of the future upside?

Most Popular Narrative: 60.9% Undervalued

According to the most widely followed valuation narrative, Gossamer Bio is currently seen as deeply undervalued. This perspective views the company’s future prospects, driven by late-stage clinical progress and expanding global partnerships, as yet to be fully appreciated in the current stock price.

*The collaboration with Chiesi Group to enter a global registrational Phase III study for seralutinib in PH-ILD enhances the opportunity for expanded indications and market reach, potentially impacting revenue positively. The anticipation of potential first-in-class treatment status for seralutinib, with observed safety and reverse remodeling effects, implies significant market adoption potential, which could improve net margins due to competitive product positioning.*

Want to know which breakthrough assumptions are powering this eye-catching fair value? The narrative is betting big on a future profit turnaround, ambitious revenue leaps, and a premium market multiple. How does the story stack up, and what specific numbers do analysts think can get Gossamer Bio there? Dig into the main drivers that set this bullish valuation apart from the crowd.

Result: Fair Value of $8.86 (UNDERVALUED)

Have a read of the narrative in full and understand what's behind the forecasts.

However, setbacks in Phase III trials or delays from regulatory challenges could quickly dampen the optimism that is driving current price targets.

Find out about the key risks to this Gossamer Bio narrative.

Another View: The Market Ratio Test

Looking at Gossamer Bio from a different angle, a traditional market ratio paints a less optimistic picture. This view suggests the stock could be on the expensive side, at least for now. Which perspective will ultimately prove right?

See what the numbers say about this price — find out in our valuation breakdown.

NasdaqGS:GOSS PS Ratio as at Sep 2025
NasdaqGS:GOSS PS Ratio as at Sep 2025

Stay updated when valuation signals shift by adding Gossamer Bio to your watchlist or portfolio. Alternatively, explore our screener to discover other companies that fit your criteria.

Build Your Own Gossamer Bio Narrative

If you see things differently or want to analyze the numbers your own way, it only takes a few minutes to shape your own perspective. Do it your way.

A great starting point for your Gossamer Bio research is our analysis highlighting 2 key rewards and 3 important warning signs that could impact your investment decision.

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

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Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team@simplywallst.com

About NasdaqGS:GOSS

Gossamer Bio

A clinical-stage biopharmaceutical company, focuses on developing and commercializing seralutinib for the treatment of pulmonary arterial hypertension (PAH) in the United States.

High growth potential and good value.

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