Shield Therapeutics plc

AIM:STX Stock Report

Market Cap: UK£69.4m

Shield Therapeutics Past Earnings Performance

Past criteria checks 0/6

Shield Therapeutics's earnings have been declining at an average annual rate of -4.4%, while the Pharmaceuticals industry saw earnings growing at 3.4% annually. Revenues have been growing at an average rate of 51.4% per year.

Key information

-4.39%

Earnings growth rate

26.49%

EPS growth rate

Pharmaceuticals Industry Growth14.12%
Revenue growth rate51.44%
Return on equityn/a
Net Margin-35.52%
Last Earnings Update31 Dec 2025

Recent past performance updates

Recent updates

Narrative Update Jun 05

STX: Pediatric And Japan Trial Milestones Will Drive Future Earnings Upside

Shield Therapeutics' analyst price target is now set at £0.14. Analysts attribute this level to unchanged fair value, discount rate and P/E assumptions, combined with modest adjustments to revenue growth and profit margin forecasts.
Narrative Update May 21

STX: Pediatric And Asia Regulatory Milestones Will Drive Future Earnings Upside

Shield Therapeutics’ latest analyst price target has been set at £0.14, with analysts attributing this unchanged fair value to a slightly adjusted discount rate, modestly revised revenue growth and profit margin assumptions, and a recalibrated future P/E multiple. What's in the News MEDLEAP Pharma, a subsidiary of Vital KSK Holdings Inc., enrolled the first patient in a Phase II exploratory clinical trial in Japan evaluating ACCRUFeR (ferric maltol) for Pulmonary Arterial Hypertension.
Narrative Update May 04

STX: Pediatric And Asia Expansion Will Drive Future Earnings Upside

Analysts have adjusted their price target on Shield Therapeutics to £0.14 per share, with the change linked to updated assumptions that maintain the fair value level while recalibrating revenue growth, profit margin and future P/E expectations. What's in the News Partner MEDLEAP Pharma enrolled the first patient in a Phase II clinical trial in Japan testing ACCRUFeR (ferric maltol) as a potential treatment for pulmonary arterial hypertension, following prior confirmation of the development plan by Japan's Pharmaceuticals and Medical Devices Agency (Product-Related Announcement).
Narrative Update Apr 18

STX: Expanded Pediatric Reach And China Entry Will Support Stronger Future Earnings

Analysts have trimmed their fair value estimate for Shield Therapeutics to £0.14 per share, citing updated assumptions that combine a lower revenue growth outlook with a higher projected profit margin and a reduced future P/E multiple. What's in the News EMA's Committee for Medicinal Products for Human Use issued a positive opinion to extend FeRACCRU's indication to include adolescents, so it is now indicated for iron deficiency in adults and pediatric patients 12 years and older in Europe, with all measures in the agreed Pediatric Investigation Plan confirmed as fulfilled (Key Developments).
Analysis Article Apr 12

Shield Therapeutics plc (LON:STX) Released Earnings Last Week And Analysts Lifted Their Price Target To UK£0.17

It's been a good week for Shield Therapeutics plc ( LON:STX ) shareholders, because the company has just released its...
Narrative Update Apr 03

STX: Pediatric And China Approvals Will Expand Future Earnings Power

Analysts have maintained their fair value estimate for Shield Therapeutics at £0.14. The discount rate remains unchanged, and updated assumptions for revenue growth, profit margin and future P/E support the latest price target view.
Narrative Update Mar 20

STX: Pediatric Label Expansion And Added Exclusivity Will Support Future Upside

Analysts have kept their fair value framework for Shield Therapeutics broadly unchanged, with a slightly adjusted profit margin outlook and future P/E assumption. These updates feed into a refreshed price target in £ terms that remains closely aligned with the prior figure.
Narrative Update Mar 06

STX: Pediatric Expansion And China Filing Will Redefine Earnings Power

Analysts have lifted their price target for Shield Therapeutics to £0.14 from £0.10, citing updated assumptions for fair value, discount rate, revenue, profit margin and future P/E that they view as better aligned with the company’s current outlook. What's in the News Shield Therapeutics filed and received acceptance of a Marketing Authorisation Application for ACCRUFeR with China’s National Medical Products Administration for adults with iron deficiency, supported by prior US FDA data and a Phase 3 study in Chinese adults with iron deficiency anemia and inflammatory bowel disease who are intolerant to oral ferrous products (Key Developments).
Narrative Update Feb 19

STX: Pediatric Expansion And Extended Exclusivity Will Support Future Upside Potential

Analysts have kept their fair value estimate for Shield Therapeutics broadly steady at £0.17 per share, reflecting only small tweaks to assumptions on discount rate, revenue growth, profit margin and future P/E that they see as refinements rather than a change in thesis. What's in the News The FDA approved an extension of the indication for ACCRUFeR (ferric maltol) to treat iron deficiency in adult and pediatric patients 10 years and older, following a priority review supported by a Phase 3 pediatric trial in children from 1 month of age with iron deficiency anemia (Key Developments).
Narrative Update Feb 05

STX: Expanded Pediatric Indications And New Market Approvals Will Drive Upside

Analysts have nudged their price target for Shield Therapeutics slightly higher, reflecting small adjustments to revenue growth, profit margin expectations, and the implied future P/E multiple. What's in the News Shield Therapeutics issued earnings guidance for 2026, indicating that it expects to deliver an operating profit in that year (company guidance).
Narrative Update Jan 22

STX: Pediatric Expansion And New Market Approvals Will Support Future Upside

Analysts have lifted their price target on Shield Therapeutics from £0.16 to about £0.17, citing updated assumptions for revenue growth, profit margins, and a slightly lower future P/E multiple. What’s in the News US FDA grants priority review approval to extend ACCRUFeR’s indication to adolescents, covering iron deficiency treatment in patients 10 years and older, backed by positive Phase 3 pediatric trial data (FORTIS/ST10-01-305) (Key Developments).
Narrative Update Jan 07

STX: Expanded Pediatric And Global Approvals Will Support Future Upside

Analysts have trimmed their price target on Shield Therapeutics slightly, citing updated expectations for revenue growth of about 41.81%, a lower projected profit margin of around 13.33% and a higher future P/E of roughly 17.49x. Together, these factors imply less upside potential from current levels in cash terms than previously estimated.
Narrative Update Dec 18

STX: Future US Label Expansion Could Still Leave Shares Vulnerable

Analysts have raised their price target for Shield Therapeutics from 0.03 dollars to 0.10 dollars, citing slightly stronger long term revenue growth expectations, while applying a higher discount rate and more conservative profit margin and valuation multiples. What's in the News Presentation of pediatric FORTIS PK sub study at the American Society of Hematology conference in December 2025 showed ferric maltol is well absorbed across pediatric age groups, with maltol rapidly metabolized and excreted, supporting its suitability for iron replacement in children and adolescents (company announcement).
Narrative Update Dec 04

STX: New Regulatory Approvals And Pediatric Data Will Drive Future Upside

Analysts have modestly increased their price target on Shield Therapeutics, citing slightly stronger projected revenue growth, a marginally lower profit margin, and a modestly higher future price-to-earnings multiple. What's in the News The Korean Ministry of Food and Drug Safety granted regulatory approval for ACCRUFeR (ferric maltol) in adults with iron deficiency, opening a new commercial market and triggering eligibility for milestones and royalties (company announcement).
Analysis Article Nov 25

Shield Therapeutics plc's (LON:STX) Subdued P/S Might Signal An Opportunity

With a median price-to-sales (or "P/S") ratio of close to 2.6x in the Pharmaceuticals industry in the United Kingdom...
Narrative Update Nov 20

STX: FDA Priority Review and Regulatory Approvals Will Drive Significant Upside

Analysts have modestly raised their price target for Shield Therapeutics from $0.16 to $0.16 per share. This change reflects updated assumptions around discount rates and profit margins, while maintaining a cautiously optimistic outlook.
Narrative Update Nov 06

STX: Upcoming FDA Decision Will Drive Confidence After Positive Pediatric Results

Analysts have maintained their price target for Shield Therapeutics at $0.16, citing stable projections in key financial metrics, including revenue growth and profit margin improvements, as justification for the unchanged valuation. What's in the News Positive efficacy, tolerability, and palatability results for the ferric maltol pediatric FORTIS clinical trial were presented at the American Association of Pediatrics National Conference.
Narrative Update Oct 22

Analysts Maintain Target for Shield Therapeutics Amid Positive Clinical News and Stable Valuation Metrics

Narrative Update on Shield Therapeutics: Analyst Price Target Revision Analysts have maintained their price target for Shield Therapeutics at £0.16. This reflects confidence in the company's prospects, given stable fair value estimates and consistent growth expectations.
Narrative Update Oct 08

Global Aging Trends And Early Detection Will Unlock Markets

Analysts have raised their price target on Shield Therapeutics from $0.14 to $0.16 per share, citing improved profit margin expectations and a steady long-term outlook, despite minor adjustments to growth forecasts. What's in the News Positive efficacy, tolerability, and palatability results for ferric maltol pediatric FORTIS clinical trial were presented at the AAP National Conference, showing significant hemoglobin improvements with no serious adverse events reported (Key Developments).
Analysis Article Aug 23

The Market Lifts Shield Therapeutics plc (LON:STX) Shares 76% But It Can Do More

Despite an already strong run, Shield Therapeutics plc ( LON:STX ) shares have been powering on, with a gain of 76% in...
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New Narrative Aug 03

Global Aging Trends And Early Detection Will Unlock Markets

An expanding addressable market and greater screening activity are driving strong prescription growth and recurring revenues for Shield's main product.
Analysis Article Jun 28

Shield Therapeutics plc (LON:STX) Soars 27% But It's A Story Of Risk Vs Reward

Shield Therapeutics plc ( LON:STX ) shares have had a really impressive month, gaining 27% after a shaky period...
Analysis Article Feb 06

Even With A 26% Surge, Cautious Investors Are Not Rewarding Shield Therapeutics plc's (LON:STX) Performance Completely

Shield Therapeutics plc ( LON:STX ) shareholders have had their patience rewarded with a 26% share price jump in the...
Analysis Article Oct 30

Shield Therapeutics plc (LON:STX) Stock's 28% Dive Might Signal An Opportunity But It Requires Some Scrutiny

The Shield Therapeutics plc ( LON:STX ) share price has softened a substantial 28% over the previous 30 days, handing...
Analysis Article Oct 12

Shield Therapeutics (LON:STX) Is Making Moderate Use Of Debt

Some say volatility, rather than debt, is the best way to think about risk as an investor, but Warren Buffett famously...
Analysis Article Aug 01

Shield Therapeutics plc's (LON:STX) Shares Leap 44% Yet They're Still Not Telling The Full Story

Despite an already strong run, Shield Therapeutics plc ( LON:STX ) shares have been powering on, with a gain of 44% in...
Analysis Article Jun 13

Increases to Shield Therapeutics plc's (LON:STX) CEO Compensation Might Cool off for now

Key Insights Shield Therapeutics will host its Annual General Meeting on 20th of June CEO Greg Madison's total...
Analysis Article May 22

Market Might Still Lack Some Conviction On Shield Therapeutics plc (LON:STX) Even After 35% Share Price Boost

Shield Therapeutics plc ( LON:STX ) shareholders are no doubt pleased to see that the share price has bounced 35% in...

Revenue & Expenses Breakdown

How Shield Therapeutics makes and spends money. Based on latest reported earnings, on an LTM basis.


Earnings and Revenue History

AIM:STX Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
31 Dec 2550-18322
30 Sep 2546-19322
30 Jun 2541-21332
31 Mar 2537-24342
31 Dec 2432-27362
30 Sep 2427-32382
30 Jun 2421-36402
31 Mar 2417-35392
31 Dec 2313-33382
30 Sep 2310-40371
30 Jun 237-47360
31 Mar 236-49351
31 Dec 225-50341
30 Sep 225-39321
30 Jun 224-30320
31 Mar 223-29301
31 Dec 212-27271
30 Sep 212-22203
30 Jun 213-18145
31 Mar 219-11134
31 Dec 2014-4124
30 Sep 2013-3113
30 Jun 2011-2102
31 Mar 206-693
31 Dec 191-1293
30 Sep 198-4104
30 Jun 19153124
31 Mar 19150145
31 Dec 1815-2165
30 Sep 188-13186
30 Jun 181-24206
31 Mar 181-26227
31 Dec 171-26236
30 Sep 171-24205
30 Jun 170-21184
31 Mar 170-19153
31 Dec 160-19133
30 Sep 160-12114
30 Jun 160-486
31 Mar 160-1957
31 Dec 150-3528
30 Sep 150-4126
30 Jun 150-4924

Quality Earnings: STX is currently unprofitable.

Growing Profit Margin: STX is currently unprofitable.


Free Cash Flow vs Earnings Analysis


Past Earnings Growth Analysis

Earnings Trend: STX is unprofitable, and losses have increased over the past 5 years at a rate of 4.4% per year.

Accelerating Growth: Unable to compare STX's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: STX is unprofitable, making it difficult to compare its past year earnings growth to the Pharmaceuticals industry (33.7%).


Return on Equity

High ROE: STX's liabilities exceed its assets, so it is difficult to calculate its Return on Equity.


Return on Assets


Return on Capital Employed


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/06/15 17:51
End of Day Share Price 2026/06/15 00:00
Earnings2025/12/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Shield Therapeutics plc is covered by 10 analysts. 3 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Howard MillerCanaccord Genuity
Mark BrewerCavendish
Michael MitchellCavendish