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Agios Pharmaceuticals, Inc.NasdaqGS:AGIO Stock Report

Market Cap US$2.1b
Share Price
US$35.09
My Fair Value
US$50
30.0% undervalued intrinsic discount
1Y-20.1%
7D-1.1%
Portfolio Value
View

Agios Pharmaceuticals, Inc.

NasdaqGS:AGIO Stock Report

Market Cap: US$2.1b

Agios Pharmaceuticals (AGIO) Stock Overview

A biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States. More details

AGIO fundamental analysis
Snowflake Score
Valuation5/6
Future Growth2/6
Past Performance3/6
Financial Health6/6
Dividends0/6

AGIO Community Fair Values

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US$50.14
FV
30.0% undervalued intrinsic discount
116.86%
Revenue growth p.a.
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4 days ago author updated this narrative

Agios Pharmaceuticals, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Agios Pharmaceuticals
Historical stock prices
Current Share PriceUS$35.76
52 Week HighUS$62.58
52 Week LowUS$23.42
Beta0.80
1 Month Change-8.43%
3 Month Change24.43%
1 Year Change-20.07%
3 Year Change26.32%
5 Year Change-14.18%
Change since IPO14.32%

Recent News & Updates

Recent updates

Agios Pharmaceuticals: A More Compelling Valuation

Jun 11

Why Agios Pharmaceuticals' (NASDAQ:AGIO) Earnings Are Weaker Than They Seem

Feb 20
Why Agios Pharmaceuticals' (NASDAQ:AGIO) Earnings Are Weaker Than They Seem

Agios Pharmaceuticals: Liver Toxicity Issues May Threaten Thalassemia Approval (Rating Downgrade)

Feb 14
author-image

Mitapivat May Launch In 2025 For Blood Disorders But Faces Regulatory And Competition Challenges

Mitapivat's launch in thalassemia and sickle cell markets promises revenue growth from new opportunities, leveraging positive Phase III data for adoption.

Agios Pharmaceuticals: Considering Risk/Reward Ahead Of FDA Decision

Jan 14

Agios Pharmaceuticals: A Long Overdue Follow Up

Dec 03

We're Not Very Worried About Agios Pharmaceuticals' (NASDAQ:AGIO) Cash Burn Rate

Sep 26
We're Not Very Worried About Agios Pharmaceuticals' (NASDAQ:AGIO) Cash Burn Rate

Agios' Mitapivat: A Potential Blockbuster In Thalassemia Treatment

Aug 27

Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Just Released Its Second-Quarter Earnings: Here's What Analysts Think

Aug 04
Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Just Released Its Second-Quarter Earnings: Here's What Analysts Think

Agios Pharmaceuticals: Potential Acquisition Target, Upcoming FDA Approvals, Promising Pipeline

Jun 12

Companies Like Agios Pharmaceuticals (NASDAQ:AGIO) Are In A Position To Invest In Growth

Jun 02
Companies Like Agios Pharmaceuticals (NASDAQ:AGIO) Are In A Position To Invest In Growth

Bearish: Analysts Just Cut Their Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Revenue and EPS estimates

Feb 17
Bearish: Analysts Just Cut Their Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Revenue and EPS estimates

Here's Why We're Not Too Worried About Agios Pharmaceuticals' (NASDAQ:AGIO) Cash Burn Situation

Jan 16
Here's Why We're Not Too Worried About Agios Pharmaceuticals' (NASDAQ:AGIO) Cash Burn Situation

Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Analysts Just Trimmed Their Revenue Forecasts By 50%

Nov 09
Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) Analysts Just Trimmed Their Revenue Forecasts By 50%

Here's Why We're Not Too Worried About Agios Pharmaceuticals' (NASDAQ:AGIO) Cash Burn Situation

Sep 26
Here's Why We're Not Too Worried About Agios Pharmaceuticals' (NASDAQ:AGIO) Cash Burn Situation

Are Investors Undervaluing Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) By 48%?

May 08
Are Investors Undervaluing Agios Pharmaceuticals, Inc. (NASDAQ:AGIO) By 48%?

We're Hopeful That Agios Pharmaceuticals (NASDAQ:AGIO) Will Use Its Cash Wisely

Feb 06
We're Hopeful That Agios Pharmaceuticals (NASDAQ:AGIO) Will Use Its Cash Wisely

Agios Pharmaceuticals (NASDAQ:AGIO) Is In A Good Position To Deliver On Growth Plans

Oct 18
Agios Pharmaceuticals (NASDAQ:AGIO) Is In A Good Position To Deliver On Growth Plans

Agios Pyrukynd for rare blood disorder gets EMA panel backing for approval in EU

Sep 16

Agios adds more than 13% after Novo deal to acquire rival Forma

Sep 01

Agios Pharmaceuticals GAAP EPS of -$1.68 beats by $0.07

Aug 04

Agios Pharmaceuticals Is A Buy On Coming Revenue Ramp

Jul 26

Agios Pharmaceuticals appoints new board chair, CEO

Jul 12

Shareholder Returns

AGIOUS BiotechsUS Market
7D-1.1%-1.5%2.4%
1Y-20.1%-7.7%20.2%

Return vs Industry: AGIO underperformed the US Biotechs industry which returned -7.7% over the past year.

Return vs Market: AGIO underperformed the US Market which returned 20.2% over the past year.

Price Volatility

Is AGIO's price volatile compared to industry and market?
AGIO volatility
AGIO Average Weekly Movement5.9%
Biotechs Industry Average Movement10.9%
Market Average Movement6.5%
10% most volatile stocks in US Market17.6%
10% least volatile stocks in US Market3.1%

Stable Share Price: AGIO has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: AGIO's weekly volatility (6%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
2007487Brian Goffwww.agios.com

Agios Pharmaceuticals, Inc., a biopharmaceutical company, discovers and develops medicines in the field of cellular metabolism in the United States. Its lead product includes PYRUKYND (mitapivat), an activator of wild-type and mutant pyruvate kinase (PK), enzymes used for the treatment of hemolytic anemias in adults with PK deficiency. The company’s PYRUKYND product also used for the treatment of sickle cell disease that is in phase 3 clinical trial; for the treatment of PK deficiency in pediatric patients; and for the treatment of adult patients with non-transfusion dependent and transfusion-dependent alpha- or beta-thalassemia.

Agios Pharmaceuticals, Inc. Fundamentals Summary

How do Agios Pharmaceuticals's earnings and revenue compare to its market cap?
AGIO fundamental statistics
Market capUS$2.08b
Earnings (TTM)US$650.08m
Revenue (TTM)US$40.88m
3.2x
P/E Ratio
50.8x
P/S Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
AGIO income statement (TTM)
RevenueUS$40.88m
Cost of RevenueUS$324.78m
Gross Profit-US$283.90m
Other Expenses-US$933.99m
EarningsUS$650.08m

Last Reported Earnings

Jun 30, 2025

Next Earnings Date

n/a

Earnings per share (EPS)11.19
Gross Margin-694.56%
Net Profit Margin1,590.42%
Debt/Equity Ratio0%

How did AGIO perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2025/08/11 20:52
End of Day Share Price 2025/08/08 00:00
Earnings2025/06/30
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Agios Pharmaceuticals, Inc. is covered by 31 analysts. 9 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Peter LawsonBarclays
George FarmerBMO Capital Markets Equity Research
Alec StranahanBofA Global Research