Agios Pharmaceuticals, Inc.

NasdaqGS:AGIO Stock Report

Market Cap: US$3.1b

Agios Pharmaceuticals Valuation

Is AGIO undervalued compared to its fair value, analyst forecasts and its price relative to the market?

Valuation Score

5/6

Valuation Score 5/6

  • Below Fair Value

  • Significantly Below Fair Value

  • Price-To-Earnings vs Peers

  • Price-To-Earnings vs Industry

  • Price-To-Earnings vs Fair Ratio

  • Analyst Forecast

Share Price vs Fair Value

What is the Fair Price of AGIO when looking at its future cash flows? For this estimate we use a Discounted Cash Flow model.

Below Fair Value: AGIO ($54.62) is trading below our estimate of fair value ($251.89)

Significantly Below Fair Value: AGIO is trading below fair value by more than 20%.


Key Valuation Metric

Which metric is best to use when looking at relative valuation for AGIO?

Key metric: As AGIO is profitable we use its Price-To-Earnings Ratio for relative valuation analysis.

The above table shows the Price to Earnings ratio for AGIO. This is calculated by dividing AGIO's market cap by their current earnings.
What is AGIO's PE Ratio?
PE Ratio4.6x
EarningsUS$674.31m
Market CapUS$3.10b

Price to Earnings Ratio vs Peers

How does AGIO's PE Ratio compare to its peers?

The above table shows the PE ratio for AGIO vs its peers. Here we also display the market cap and forecasted growth for additional consideration.
CompanyForward PEEstimated GrowthMarket Cap
Peer Average48.5x
PTGX Protagonist Therapeutics
14.2x-31.4%US$2.3b
CPRX Catalyst Pharmaceuticals
17.7x17.5%US$2.6b
ADMA ADMA Biologics
74.1x30.5%US$4.9b
MNKD MannKind
88x39.7%US$1.9b
AGIO Agios Pharmaceuticals
4.6x-56.7%US$3.1b

Price-To-Earnings vs Peers: AGIO is good value based on its Price-To-Earnings Ratio (4.6x) compared to the peer average (48.5x).


Price to Earnings Ratio vs Industry

How does AGIO's PE Ratio compare vs other companies in the US Biotechs Industry?

11 CompaniesPrice / EarningsEstimated GrowthMarket Cap
Industry Avg.16.8x28.3%
AGIO Agios Pharmaceuticals
4.6x-56.7%US$3.10b
ROIV Roivant Sciences
1.8x-46.3%US$8.23b
INBX Inhibrx Biosciences
0.1xn/aUS$206.86m
AGIO 4.6xIndustry Avg. 16.8xNo. of Companies11PE020406080100+
11 CompaniesEstimated GrowthMarket Cap
Industry Avg.16.8x28.3%
AGIO Agios Pharmaceuticals
4.6x-56.7%US$3.10b
No more companies

Price-To-Earnings vs Industry: AGIO is good value based on its Price-To-Earnings Ratio (4.6x) compared to the US Biotechs industry average (17.2x).


Price to Earnings Ratio vs Fair Ratio

What is AGIO's PE Ratio compared to its Fair PE Ratio? This is the expected PE Ratio taking into account the company's forecast earnings growth, profit margins and other risk factors.

AGIO PE Ratio vs Fair Ratio.
Fair Ratio
Current PE Ratio4.6x
Fair PE Ratio7.6x

Price-To-Earnings vs Fair Ratio: AGIO is good value based on its Price-To-Earnings Ratio (4.6x) compared to the estimated Fair Price-To-Earnings Ratio (7.6x).


Analyst Price Targets

What is the analyst 12-month forecast and do we have any statistical confidence in the consensus price target?

The above table shows the analyst AGIO forecast and predictions for the stock price in 12 month’s time.
DateShare PriceAverage 1Y Price TargetDispersionHighLow1Y Actual priceAnalysts
CurrentUS$54.62
US$53.88
-1.4%
6.6%US$57.00US$46.00n/a8
Nov ’25US$44.87
US$53.88
+20.1%
6.6%US$57.00US$46.00n/a8
Oct ’25US$42.47
US$54.50
+28.3%
7.1%US$57.00US$46.00n/a6
Sep ’25US$45.91
US$54.33
+18.3%
8.1%US$60.00US$46.00n/a6
Aug ’25US$44.50
US$53.83
+21.0%
8.9%US$60.00US$46.00n/a6
Jul ’25US$43.38
US$52.83
+21.8%
8.9%US$61.00US$46.00n/a6
Jun ’25US$36.34
US$46.00
+26.6%
18.2%US$59.00US$33.00n/a5
May ’25US$33.66
US$40.67
+20.8%
20.3%US$49.00US$29.00n/a6
Apr ’25US$28.86
US$40.67
+40.9%
20.3%US$49.00US$29.00n/a6
Mar ’25US$32.27
US$40.67
+26.0%
20.3%US$49.00US$29.00n/a6
Feb ’25US$22.96
US$40.17
+74.9%
20.2%US$49.00US$28.00n/a6
Jan ’25US$22.27
US$38.33
+72.1%
19.0%US$49.00US$28.00n/a6
Dec ’24US$22.90
US$38.00
+65.9%
19.2%US$49.00US$28.00n/a6
Nov ’24US$21.30
US$38.50
+80.8%
13.8%US$46.00US$32.00US$44.876
Oct ’24US$24.75
US$38.83
+56.9%
13.3%US$46.00US$32.00US$42.476
Sep ’24US$28.17
US$38.83
+37.9%
13.3%US$46.00US$32.00US$45.916
Aug ’24US$26.79
US$38.67
+44.3%
12.8%US$46.00US$32.00US$44.506
Jul ’24US$28.32
US$38.67
+36.5%
12.8%US$46.00US$32.00US$43.386
Jun ’24US$25.71
US$36.67
+42.6%
10.2%US$41.00US$32.00US$36.346
May ’24US$23.19
US$36.83
+58.8%
9.8%US$41.00US$32.00US$33.666
Apr ’24US$22.97
US$36.83
+60.4%
9.8%US$41.00US$32.00US$28.866
Mar ’24US$25.01
US$36.83
+47.3%
9.8%US$41.00US$32.00US$32.276
Feb ’24US$29.56
US$36.20
+22.5%
8.8%US$40.00US$32.00US$22.965
Jan ’24US$28.08
US$36.20
+28.9%
10.7%US$43.00US$32.00US$22.275
Dec ’23US$29.39
US$36.20
+23.2%
10.7%US$43.00US$32.00US$22.905
Nov ’23US$28.37
US$37.20
+31.1%
28.9%US$48.00US$17.00US$21.305

Analyst Forecast: Target price is lower than the current share price.


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