Loading...
ANRO logo

Alto Neuroscience, Inc.NYSE:ANRO Stock Report

Market Cap US$755.0m
Share Price
US$21.22
US$35.13
39.6% undervalued intrinsic discount
1Y600.3%
7D-7.7%
1D
Portfolio Value
View

Alto Neuroscience, Inc.

NYSE:ANRO Stock Report

Market Cap: US$755.0m

ANRO Community Fair Values

Create Narrative

See what 6 others think this stock is worth. Follow their fair value or set your own to get alerts.

Alto Neuroscience, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Alto Neuroscience
Historical stock prices
Current Share PriceUS$21.22
52 Week HighUS$28.44
52 Week LowUS$2.15
Beta1.65
1 Month Change-21.87%
3 Month Change20.43%
1 Year Change600.33%
3 Year Changen/a
5 Year Changen/a
Change since IPO2.51%

Recent News & Updates

Recent updates

Analysis Article Jan 01

Alto Neuroscience, Inc.'s (NYSE:ANRO) Intrinsic Value Is Potentially 33% Above Its Share Price

Key Insights Using the 2 Stage Free Cash Flow to Equity, Alto Neuroscience fair value estimate is US$23.71 Alto...
Analysis Article Nov 22

Alto Neuroscience (NYSE:ANRO) Has Debt But No Earnings; Should You Worry?

Warren Buffett famously said, 'Volatility is far from synonymous with risk.' So it might be obvious that you need to...
Seeking Alpha Mar 21

Alto Neuroscience: Potential First-In-Class Approach To Targeting CNS Disorders

Summary Results from phase 2b study, using ALTO-100 for the treatment of patients with Major Depressive Disorder, expected in the 2nd half of 2024. Results from phase 2b study, using ALTO-300 for the treatment of patients with Major Depressive Disorder, expected in the 1st half of 2025. The major depressive disorder market across the 8 major markets is expected to grow to $9.6 billion in 2029. The Precision Psychiatry Platform is designed to help the company develop drugs where patients are likely to respond to treatment based on biomarker confirmation. Read the full article on Seeking Alpha

Shareholder Returns

ANROUS PharmaceuticalsUS Market
7D-7.7%4.9%1.0%
1Y600.3%44.2%28.7%

Return vs Industry: ANRO exceeded the US Pharmaceuticals industry which returned 41.8% over the past year.

Return vs Market: ANRO exceeded the US Market which returned 27.1% over the past year.

Price Volatility

Is ANRO's price volatile compared to industry and market?
ANRO volatility
ANRO Average Weekly Movement10.5%
Pharmaceuticals Industry Average Movement10.1%
Market Average Movement7.2%
10% most volatile stocks in US Market16.4%
10% least volatile stocks in US Market3.1%

Stable Share Price: ANRO has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: ANRO's weekly volatility has decreased from 18% to 10% over the past year.

About the Company

FoundedEmployeesCEOWebsite
201968Amit Etkinwww.altoneuroscience.com

Alto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company in the United States. The company’s product pipeline includes ALTO-100, which is in Phase 2b clinical trial for the treatment of patients with bipolar depression (BPD). It also develops ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties, which is in Phase 2b clinical trial to treat patients with major depressive disorder (MDD); ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor that is in Phase 2 proof-of-concept (POC) trial for the treatment of cognitive impairment associated with schizophrenia; ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist, which is in Phase 2 POC trial to treat patients with MDD and higher levels of anhedonia; ALTO-202, an investigational orally bioavailable antagonist of the GluN2B subunit of the NMDA receptor that is in Phase 1 clinical trial for the treatment of MDD; and ALTO-208, a fixed-dose combination of pramipexole and aprepitant, an antiemetic, neurokinin-1 (NK-1) receptor antagonist for patients with Parkinson’s disease for patients with Parkinson’s disease.

Alto Neuroscience, Inc. Fundamentals Summary

How do Alto Neuroscience's earnings and revenue compare to its market cap?
ANRO fundamental statistics
Market capUS$755.04m
Earnings (TTM)-US$74.31m
Revenue (TTM)n/a
0.0x
P/S Ratio
-10.0x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
ANRO income statement (TTM)
RevenueUS$0
Cost of RevenueUS$0
Gross ProfitUS$0
Other ExpensesUS$74.31m
Earnings-US$74.31m

Last Reported Earnings

Mar 31, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-2.12
Gross Margin0.00%
Net Profit Margin0.00%
Debt/Equity Ratio7.5%

How did ANRO perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/22 11:11
End of Day Share Price 2026/05/22 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Alto Neuroscience, Inc. is covered by 13 analysts. 11 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Brian SkorneyBaird
Tazeen AhmadBofA Global Research
Thomas ShraderBTIG