Prelude Therapeutics (PRLD) Stock Overview
A clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. More details
| Snowflake Score | |
|---|---|
| Valuation | 3/6 |
| Future Growth | 5/6 |
| Past Performance | 0/6 |
| Financial Health | 5/6 |
| Dividends | 0/6 |
PRLD Community Fair Values
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Prelude Therapeutics Incorporated Competitors
Price History & Performance
| Historical stock prices | |
|---|---|
| Current Share Price | US$1.71 |
| 52 Week High | US$4.22 |
| 52 Week Low | US$0.61 |
| Beta | 1.06 |
| 1 Month Change | 12.50% |
| 3 Month Change | 47.41% |
| 1 Year Change | 90.91% |
| 3 Year Change | -65.38% |
| 5 Year Change | -97.80% |
| Change since IPO | -93.47% |
Recent News & Updates
Recent updates
Prelude Therapeutics Incorporated's (NASDAQ:PRLD) 66% Share Price Plunge Could Signal Some Risk
Dec 03
Prelude Therapeutics: A Subtle Shift In Pipeline Underscores Funding Challenges
Nov 03Prelude Therapeutics (NASDAQ:PRLD) Will Have To Spend Its Cash Wisely
Jun 16We Think Prelude Therapeutics (NASDAQ:PRLD) Needs To Drive Business Growth Carefully
Mar 17We're Keeping An Eye On Prelude Therapeutics' (NASDAQ:PRLD) Cash Burn Rate
Sep 16We Think Prelude Therapeutics (NASDAQ:PRLD) Needs To Drive Business Growth Carefully
May 09Prelude Therapeutics: Scientifically Interesting Oncology Company With Preclinical Data
Feb 03Here's Why We're Watching Prelude Therapeutics' (NASDAQ:PRLD) Cash Burn Situation
Sep 17We Think Prelude Therapeutics (NASDAQ:PRLD) Needs To Drive Business Growth Carefully
May 28Here's Why We're Not Too Worried About Prelude Therapeutics' (NASDAQ:PRLD) Cash Burn Situation
Jan 28We're Hopeful That Prelude Therapeutics (NASDAQ:PRLD) Will Use Its Cash Wisely
Oct 27Prelude wins FDA clearance to start Phase 1 trial for cancer candidate
Oct 18Prelude downgraded at Morgan Stanley ahead of key update
Sep 09We're Not Very Worried About Prelude Therapeutics' (NASDAQ:PRLD) Cash Burn Rate
Jun 28Companies Like Prelude Therapeutics (NASDAQ:PRLD) Are In A Position To Invest In Growth
Mar 14We Think Prelude Therapeutics (NASDAQ:PRLD) Can Afford To Drive Business Growth
Dec 14Companies Like Prelude Therapeutics (NASDAQ:PRLD) Are In A Position To Invest In Growth
Jul 05What Type Of Shareholders Own The Most Number of Prelude Therapeutics Incorporated (NASDAQ:PRLD) Shares?
Feb 16
Read This Before Selling Prelude Therapeutics Incorporated (NASDAQ:PRLD) Shares
Dec 25Shareholder Returns
| PRLD | US Biotechs | US Market | |
|---|---|---|---|
| 7D | 17.1% | -0.9% | -0.6% |
| 1Y | 90.9% | 20.5% | 12.4% |
Return vs Industry: PRLD exceeded the US Biotechs industry which returned 20.5% over the past year.
Return vs Market: PRLD exceeded the US Market which returned 12.4% over the past year.
Price Volatility
| PRLD volatility | |
|---|---|
| PRLD Average Weekly Movement | 49.0% |
| Biotechs Industry Average Movement | 11.3% |
| Market Average Movement | 6.5% |
| 10% most volatile stocks in US Market | 17.1% |
| 10% least volatile stocks in US Market | 3.0% |
Stable Share Price: PRLD's share price has been volatile over the past 3 months compared to the US market.
Volatility Over Time: PRLD's weekly volatility has increased from 28% to 49% over the past year.
About the Company
| Founded | Employees | CEO | Website |
|---|---|---|---|
| 2016 | 131 | Kris Vaddi | preludetx.com |
Prelude Therapeutics Incorporated, a clinical-stage precision oncology company, focuses on the discovery and development of novel precision cancer medicines to underserved patients. It is developing PRT3789, a selective degrader of SMARCA2 protein for the treatment of advanced or metastatic solid tumors with loss of SMARCA4 due to truncating mutation and/or deletion; PRT7732, a selective and orally bioavailable SMARCA2 degraders to treat advanced or metastatic solid tumors; and PRT2527, a cyclin-dependent kinase 9 inhibitor for the treatment of advanced solid tumors. The company’s CDK9 program is a regulator of cancer-promoting transcriptional programs, including MCL1, MYC, and MYB.
Prelude Therapeutics Incorporated Fundamentals Summary
| PRLD fundamental statistics | |
|---|---|
| Market cap | US$140.90m |
| Earnings (TTM) | -US$111.77m |
| Revenue (TTM) | US$10.50m |
Is PRLD overvalued?
See Fair Value and valuation analysisEarnings & Revenue
| PRLD income statement (TTM) | |
|---|---|
| Revenue | US$10.50m |
| Cost of Revenue | US$0 |
| Gross Profit | US$10.50m |
| Other Expenses | US$122.27m |
| Earnings | -US$111.77m |
Last Reported Earnings
Sep 30, 2025
Next Earnings Date
n/a
| Earnings per share (EPS) | -1.36 |
| Gross Margin | 100.00% |
| Net Profit Margin | -1,064.50% |
| Debt/Equity Ratio | 0% |
How did PRLD perform over the long term?
See historical performance and comparisonCompany Analysis and Financial Data Status
| Data | Last Updated (UTC time) |
|---|---|
| Company Analysis | 2025/12/15 22:53 |
| End of Day Share Price | 2025/12/12 00:00 |
| Earnings | 2025/09/30 |
| Annual Earnings | 2024/12/31 |
Data Sources
The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.
| Package | Data | Timeframe | Example US Source * |
|---|---|---|---|
| Company Financials | 10 years |
| |
| Analyst Consensus Estimates | +3 years |
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| Market Prices | 30 years |
| |
| Ownership | 10 years |
| |
| Management | 10 years |
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| Key Developments | 10 years |
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* Example for US securities, for non-US equivalent regulatory forms and sources are used.
Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.
Analysis Model and Snowflake
Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.
Learn about the world class team who designed and built the Simply Wall St analysis model.
Industry and Sector Metrics
Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.
Analyst Sources
Prelude Therapeutics Incorporated is covered by 5 analysts. 3 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.
| Analyst | Institution |
|---|---|
| Tazeen Ahmad | BofA Global Research |
| Reni Benjamin | Citizens JMP Securities, LLC |
| Graig Suvannavejh | Goldman Sachs |