Prelude Therapeutics Ownership

Who are the major shareholders and have insiders been buying or selling?

Recent Insider Transactions

NasdaqGS:PRLD Recent Insider Transactions by Companies or Individuals
Date	Value	Name	Entity	Shares	Max Price
25 May 23	BuyUS$9,790	Krishna Vaddi	Individual	1,900	US$5.31
24 May 23	BuyUS$12,936	Bryant Lim	Individual	2,400	US$5.39
23 May 23	BuyUS$66,749	Krishna Vaddi	Individual	11,856	US$5.63
23 May 23	BuyUS$27,500	Laurent Chardonnet	Individual	5,000	US$5.50
22 May 23	BuyUS$4,999,999	OrbiMed Advisors LLC	Company	869,565	US$5.75

Insider Buying: Insufficient data to determine if insiders have bought more shares than they have sold in the past 3 months.

Dilution of Shares: Shareholders have been diluted in the past year, with total shares outstanding growing by 15.1%.

Top 25 shareholders own 91.77% of the company

Ownership	Name	Shares	Current Value	Change %	Portfolio %
31.5%	Baker Bros. Advisors LP	17,293,897	US$97.4m	0%	1.22%
30.2%	OrbiMed Advisors LLC	16,589,442	US$93.4m	0%	1.32%
7.53%	Deerfield Management Company, L.P. Series C	4,133,000	US$23.3m	0%	0.48%
4.68%	Tavistock Life Sciences	2,568,287	US$14.5m	2.94%	0.83%
3.94%	Krishna Vaddi	2,163,369	US$12.2m	0%	no data
2%	BlackRock, Inc.	1,095,589	US$6.2m	2.54%	no data
1.9%	T. Rowe Price Group, Inc.	1,042,737	US$5.9m	-2.26%	no data
1.83%	The Vanguard Group, Inc.	1,006,856	US$5.7m	3.42%	no data
1.01%	Blue Sky Trust, Endowment Arm	551,776	US$3.1m	0%	no data
0.93%	Massachusetts Financial Services Company	510,749	US$2.9m	0.09%	no data
0.91%	Paul Friedman	500,098	US$2.8m	0%	no data
0.64%	Geode Capital Management, LLC	349,367	US$2.0m	5.52%	no data
0.58%	Sio Capital Management, LLC	320,394	US$1.8m	-8.46%	0.69%
0.56%	Andrew Combs	307,207	US$1.7m	0%	no data
0.54%	Morgan Stanley, Investment Banking and Brokerage Investments	296,862	US$1.7m	22%	no data
0.48%	FMR LLC	264,686	US$1.5m	0.04%	no data
0.39%	Renaissance Technologies LLC	216,400	US$1.2m	55.3%	no data
0.39%	State Street Global Advisors, Inc.	212,234	US$1.2m	13.4%	no data
0.32%	Peggy Scherle	175,685	US$989.1k	0%	no data
0.29%	TD Asset Management, Inc.	160,652	US$904.5k	0%	no data
0.27%	Bridgeway Capital Management, LLC	148,749	US$837.5k	303%	0.01%
0.24%	Jacobs Levy Equity Management Inc	131,307	US$739.2k	-8.79%	no data
0.23%	Charles Schwab Investment Management, Inc.	124,700	US$702.1k	0%	no data
0.21%	Northern Trust Global Investments	114,097	US$642.4k	-1.23%	no data
0.18%	Millennium Management LLC	96,966	US$545.9k	51.8%	no data