Praxis Precision Medicines Ownership

Who are the major shareholders and have insiders been buying or selling?

Recent Insider Transactions

Insider Buying: Insufficient data to determine if insiders have bought more shares than they have sold in the past 3 months.

Dilution of Shares: Shareholders have been substantially diluted in the past year, with total shares outstanding growing by 117.5%.

Top 25 shareholders own 86% of the company

Ownership	Name	Shares	Current Value	Change %	Portfolio %
6.99%	BlackRock, Inc.	1,302,435	US$100.1m	0.65%	no data
6.63%	RA Capital Management, L.P.	1,235,599	US$95.0m	49.2%	1.1%
6.08%	Adage Capital Management, L.P.	1,134,083	US$87.2m	-18.6%	0.16%
6%	Perceptive Advisors LLC	1,119,035	US$86.0m	49.2%	1.86%
6%	Point72 Asset Management, L.P.	1,117,634	US$85.9m	9.56%	0.21%
5.24%	The Vanguard Group, Inc.	977,145	US$75.1m	31.3%	no data
5.04%	T. Rowe Price Group, Inc.	938,579	US$72.2m	75.1%	0.01%
4.4%	State Street Global Advisors, Inc.	819,142	US$63.0m	1,740%	no data
4.02%	Verition Fund Management LLC	748,320	US$57.5m	37.2%	0.48%
3.79%	VR Adviser, LLC	706,131	US$54.3m	0%	2.27%
3.68%	Cormorant Asset Management, LP	685,000	US$52.7m	-47.7%	2.46%
2.86%	Soleus Capital Management, L.P.	533,015	US$41.0m	1,330%	3.2%
2.43%	PFM Health Sciences, LP	453,146	US$34.8m	-5.12%	2.09%
2.39%	Franklin Resources, Inc.	445,208	US$34.2m	85.6%	0.01%
2.36%	Vestal Point Capital, LP	440,000	US$33.8m	110%	2.36%
2.23%	Kingdon Capital Management, L.L.C.	415,000	US$31.9m	18.6%	4.66%
2.14%	Geode Capital Management, LLC	398,838	US$30.7m	0.96%	no data
2.09%	Deep Track Capital, LP	389,546	US$29.9m	0%	0.78%
2.05%	Janus Henderson Group plc	381,685	US$29.3m	23.1%	0.01%
1.88%	Velan Capital Partners LP	350,666	US$27.0m	0%	29.23%
1.82%	5AM Venture Management, LLC	340,000	US$26.1m	0%	4.88%
1.56%	FMR LLC	290,955	US$22.4m	-34.3%	no data
1.52%	Sphera Funds Management Ltd	283,424	US$21.8m	60%	3.58%
1.42%	Driehaus Capital Management LLC	264,688	US$20.3m	-0.68%	0.13%
1.4%	Octagon Capital Advisors LP	260,000	US$20.0m	0%	3.12%