Praxis Precision Medicines Ownership

Who are the major shareholders and have insiders been buying or selling?

Recent Insider Transactions

NasdaqGS:PRAX Recent Insider Transactions by Companies or Individuals
Date	Value	Name	Entity	Role	Shares	Max Price
05 Oct 23	BuyUS$25,375	Jill DeSimone	Individual		966.67	US$26.25
27 Jun 23	BuyUS$10,587	Marcio De'Souza	Individual		666.67	US$15.88

Insider Buying: Insufficient data to determine if insiders have bought more shares than they have sold in the past 3 months.

Dilution of Shares: Shareholders have been substantially diluted in the past year, with total shares outstanding growing by 115.2%.

Top 25 shareholders own 73.39% of the company

Ownership	Name	Shares	Current Value	Change %	Portfolio %
8.14%	Adage Capital Management, L.P.	1,393,028	US$52.5m	88.6%	0.09%
7.66%	Cormorant Asset Management, LP	1,310,000	US$49.4m	107%	2.76%
5.96%	Point72 Asset Management, L.P.	1,020,073	US$38.4m	34.5%	0.08%
4.84%	RA Capital Management, L.P.	828,380	US$31.2m	0%	0.42%
4.8%	Perceptive Advisors LLC	821,589	US$31.0m	0%	0.65%
4.35%	The Vanguard Group, Inc.	744,069	US$28.0m	101%	no data
4.13%	VR Adviser, LLC	706,126	US$26.6m	99.7%	1.26%
3.19%	Verition Fund Management LLC	545,408	US$20.6m	-22.4%	0.22%
3.13%	T. Rowe Price Group, Inc.	535,999	US$20.2m	0%	no data
2.79%	PFM Health Sciences, LP	477,605	US$18.0m	-27.3%	0.96%
2.69%	OrbiMed Advisors LLC	460,512	US$17.4m	0%	0.24%
2.59%	FMR LLC	442,571	US$16.7m	385,000%	no data
2.05%	Velan Capital Partners LP	350,666	US$13.2m	1.45%	7.9%
2.05%	Kingdon Capital Management, L.L.C.	350,000	US$13.2m	0.96%	1.67%
1.99%	5AM Venture Management, LLC	340,000	US$12.8m	0%	2.41%
1.81%	Janus Henderson Group plc	310,059	US$11.7m	0%	no data
1.56%	Driehaus Capital Management LLC	266,496	US$10.0m	0%	0.07%
1.52%	Octagon Capital Advisors LP	260,000	US$9.8m	0%	1.44%
1.32%	Laurion Capital Management LP	225,000	US$8.5m	0%	0.25%
1.3%	BlackRock, Inc.	221,745	US$8.4m	75.2%	no data
1.23%	Vestal Point Capital, LP	210,000	US$7.9m	0%	0.7%
1.12%	CIBC Asset Management Inc.	192,304	US$7.2m	10.6%	0.01%
1.11%	Silverarc Capital Management, LLC	190,556	US$7.2m	-32.9%	2.34%
1.04%	Sphera Funds Management Ltd	177,139	US$6.7m	-46.2%	1.1%
1.03%	Millennium Management LLC	176,952	US$6.7m	692%	0.01%