Praxis Precision Medicines, Inc.

NasdaqGS:PRAX Stock Report

Market Cap: US$7.4b

Praxis Precision Medicines Past Earnings Performance

Past criteria checks 0/6

Praxis Precision Medicines's earnings have been declining at an average annual rate of -13.4%, while the Biotechs industry saw earnings growing at 36.2% annually. Revenues have been growing at an average rate of 54.9% per year.

Key information

-13.43%

Earnings growth rate

39.98%

EPS growth rate

Biotechs Industry Growth17.04%
Revenue growth rate54.86%
Return on equity-23.16%
Net Marginn/a
Last Earnings Update31 Mar 2026

Recent past performance updates

Recent updates

Seeking Alpha • Jun 05

Praxis' Premium Price May Reflect Unrealistic Market Prospects In Essential Tremor

Summary Praxis Precision Medicines, Inc. is valued as a pure-play on ulixacaltamide’s commercial launch in essential tremor, with pipeline optionality limited. I maintain a cautious Hold rating, as PRAX trades above my fair value estimate of $223.73 versus a current share price of $265. Key risks include real-world persistence, payer step edits, and competition from cheap off-label generics, which could materially limit ulixacaltamide’s addressable market and duration. Pipeline assets outside ET, such as elsunersen and vormatrigine, offer little valuation support, especially after recent clinical setbacks and negative risk-adjusted NPV. Read the full article on Seeking Alpha
Analysis Article • Jul 18

We're Hopeful That Praxis Precision Medicines (NASDAQ:PRAX) Will Use Its Cash Wisely

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Seeking Alpha • Mar 04

Praxis: A High-Risk, High-Reward Epilepsy Play Post Ulixacaltamide (Rating Upgrade)

Summary Ulixacaltamide’s Phase 3 study was recommended to stop for futility, significantly lowering its chances of success in essential tremor. Investor focus shifts to the epilepsy pipeline, led by vormatrigine (focal epilepsy) and relutrigine (SCN2A/SCN8A-DEEs). Vormatrigine must differentiate from Xcopri and XEN1101 in a highly competitive focal epilepsy market. Relutrigine showed promising seizure reduction in rare pediatric epilepsies but needs confirmation in larger pivotal trials. Praxis has $400M+ cash, funding operations into 2028, with key epilepsy trial readouts expected in 2H 2025. Read the full article on Seeking Alpha
Seeking Alpha • Dec 26

Praxis Precision Medicines: Multiple Potential Drivers

Summary Praxis Precision Medicines, Inc., a promising clinical stage biopharma concern, has seen significant stock gains in the second half of 2024. Analyst firms are quite bullish on the stock, with eight firms recently issuing Buy ratings and price targets ranging from $114 to $305 per share. The company has several potential drivers with its late-stage pipeline candidates and possesses a decent balance sheet. While the stock should only be considered by aggressive investors given its recent rally, I have taken a small position in PRAX stock via covered call orders. An analysis around Praxis Precision Medicines follows in the paragraphs below. Read the full article on Seeking Alpha
Seeking Alpha • Oct 13

Praxis Precision Medicines: Great Price Movement, But Still Not Convinced

Summary Praxis Precision Medicines has shown impressive growth, but past trial failures and current risks warrant caution before investing. The lead candidate, Ulixacaltamide, is in a phase 3 trial for essential tremor, with results expected by the end of 2024. PRAX-628 shows promise for epilepsy, but the small patient cohort and competitive landscape raise concerns. Despite significant stock gains, I remain unconvinced and seek more data before making an investment decision. Read the full article on Seeking Alpha
Seeking Alpha • Mar 26

Praxis: 2nd Half 2024 ET Readout Could Lead To U.S. Regulatory Filing

Summary Praxis Precision Medicines, Inc. results from the phase 3 Essential3 program, using ulixacaltamide for the treatment of patients with essential tremor, expected in the 2nd half of 2024. Company believes that the essential tremor U.S. market opportunity could be $4 billion. Positive data achieved in phase 2 study, using PRAX-628 for focal epilepsy; Phase 2b study targeting this very same patient population to be initiated 2nd half of 2024. With cash on hand, plus underwritten public offering that brought in $161.7 million in cash, Praxis Precision Medicines believes it can fund its operations into 2026. Read the full article on Seeking Alpha

Revenue & Expenses Breakdown

How Praxis Precision Medicines makes and spends money. Based on latest reported earnings, on an LTM basis.

Earnings and Revenue History

NasdaqGS:PRAX Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
31 Mar 260-327730
31 Dec 250-303590
30 Sep 257-273550
30 Jun 258-251570
31 Mar 258-213550
31 Dec 249-183560
30 Sep 242-151510
30 Jun 242-124450
31 Mar 242-125440
31 Dec 232-123420
30 Sep 232-138450
30 Jun 231-15750-89
31 Mar 231-183570
31 Dec 220-214600
30 Sep 220-2316244
30 Jun 220-23259166
31 Mar 220-20854102
31 Dec 210-16747120
30 Sep 210-1354193
30 Jun 210-1113373
31 Mar 210-882556
31 Dec 200-701745
30 Sep 200-53934
30 Jun 200-44731
31 Mar 200-41629
31 Dec 190-41630

Quality Earnings: PRAX is currently unprofitable.

Growing Profit Margin: PRAX is currently unprofitable.

Free Cash Flow vs Earnings Analysis

Past Earnings Growth Analysis

Earnings Trend: PRAX is unprofitable, and losses have increased over the past 5 years at a rate of 13.4% per year.

Accelerating Growth: Unable to compare PRAX's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: PRAX is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (54.5%).

Return on Equity

High ROE: PRAX has a negative Return on Equity (-23.16%), as it is currently unprofitable.

Return on Assets

Return on Capital Employed

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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/06/16 20:57
End of Day Share Price 2026/06/16 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Praxis Precision Medicines, Inc. is covered by 27 analysts. 17 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Brian SkorneyBaird
Joel BeattyBaird
null nullBaird