Puma Biotechnology, Inc.

NasdaqGS:PBYI Stock Report

Market Cap: US$346.6m

Puma Biotechnology Future Growth

Future criteria checks 0/6

Puma Biotechnology's revenue and earnings are forecast to decline at 1.6% and 49.9% per annum respectively while EPS is expected to decline by 51.4% per annum.

Key information

-49.9%

Earnings growth rate

-51.38%

EPS growth rate

Biotechs earnings growth25.5%
Revenue growth rate-1.6%
Future return on equityn/a
Analyst coverage

Low

Last updated08 May 2026

Recent future growth updates

Analysis Article May 11

Puma Biotechnology, Inc. (NASDAQ:PBYI) Analysts Are Pretty Bullish On The Stock After Recent Results

A week ago, Puma Biotechnology, Inc. ( NASDAQ:PBYI ) came out with a strong set of first-quarter numbers that could...

Recent updates

Narrative Update May 19

PBYI: 2026 Profit Outlook Will Likely Fail To Justify Current Pricing

Analysts have adjusted their price target on Puma Biotechnology to reflect updated views on fair value at $5.00. This change is accompanied by revised assumptions regarding the discount rate, revenue growth, profit margins, and a higher future P/E multiple.
Analysis Article May 15

There May Be Reason For Hope In Puma Biotechnology's (NASDAQ:PBYI) Disappointing Earnings

Puma Biotechnology, Inc.'s ( NASDAQ:PBYI ) earnings announcement last week didn't impress shareholders. However, our...
Analysis Article May 11

Puma Biotechnology, Inc. (NASDAQ:PBYI) Analysts Are Pretty Bullish On The Stock After Recent Results

A week ago, Puma Biotechnology, Inc. ( NASDAQ:PBYI ) came out with a strong set of first-quarter numbers that could...
Narrative Update Apr 28

PBYI: 2026 Profit Outlook Will Likely Fail To Justify Current Pricing

Analysts have adjusted their price target on Puma Biotechnology slightly, with the updated fair value moving to $5.00. This reflects refreshed views on the discount rate, long-term revenue growth, profit margins, and future P/E assumptions.
Narrative Update Apr 11

PBYI: 2026 Profitability Guidance Will Likely Fail To Support Current Pricing

Analysts have slightly adjusted their price target on Puma Biotechnology, keeping fair value around $5.00 while fine tuning inputs such as discount rate, revenue growth, profit margin, and future P/E to reflect updated assumptions about the company’s risk profile and earnings potential. What's in the News Puma Biotechnology issued new earnings guidance for the first quarter of 2026, projecting net product revenue of US$36 million to US$39 million and royalty revenue of US$2 million to US$3 million, for total revenue of US$38 million to US$42 million, with an expected net loss of US$8 million to US$10 million (company guidance).
Narrative Update Mar 28

PBYI: 2026 Guidance Will Likely Fail To Justify Current Pricing

Analysts have modestly adjusted their price target on Puma Biotechnology, reflecting small refinements to assumptions around the discount rate, revenue growth, profit margins, and forward P/E rather than a major shift in the outlook. What's in the News Puma Biotechnology issued earnings guidance for the first quarter of 2026, projecting net product revenue of US$36 million to US$39 million and royalty revenue of US$2 million to US$3 million, for total revenue of US$38 million to US$42 million (Key Developments).
Narrative Update Mar 13

PBYI: Index Inclusion Will Likely Fail To Offset Weak Revenue Outlook

Analysts have trimmed their price target on Puma Biotechnology to $5.00 from $5.00 in response to updated assumptions regarding discount rates, revenue growth, profit margins, and future P/E. These changes leave the fair value estimate effectively unchanged.
Narrative Update Feb 26

PBYI: Index Addition And Refined Assumptions Will Still Limit Upside Potential

Analysts have adjusted their price target on Puma Biotechnology to reflect an updated fair value of $5.00, a slightly lower discount rate of 7.25%, almost unchanged revenue growth at about 97%, a stable profit margin near 11.02%, and a marginally different future P/E of roughly 13.33x, indicating a largely intact valuation framework with only fine tuning to their assumptions. What's in the News Puma Biotechnology, Inc.
Narrative Update Feb 11

PBYI: Index Inclusion And Higher Multiple Will Likely Fail To Support Upside

Analysts have raised their price target on Puma Biotechnology to $5.00 from $3.50, citing updates to fair value estimates, discount rate assumptions, and expected future P/E levels. What's in the News Puma Biotechnology, Inc.
Narrative Update Jan 26

PBYI: Higher 2025 Guidance And Index Addition Will Not Sustain Current Optimism

Analysts have slightly adjusted their price target on Puma Biotechnology, citing modest tweaks to assumptions on discount rate, revenue growth, profit margin and future P/E. Together, these changes translate into a small refinement in estimated fair value rather than a major reset in outlook.
Narrative Update Jan 12

PBYI: Higher 2025 Guidance And Index Inclusion Will Still Look Overpriced

Analysts have lifted their price targets on Puma Biotechnology, citing updates to their models that reflect a fair value estimate of $5.00, adjusted discount rates, revised revenue growth assumptions of about 1% instead of a 3% decline, higher projected profit margins of around 10% compared with about 3%, and a lower assumed future P/E multiple near 14 versus about 37. What's in the News Puma Biotechnology, Inc.
Narrative Update Dec 26

PBYI: Raised 2025 Guidance Will Still Fail To Support Current Optimism

Analysts have modestly trimmed their price target on Puma Biotechnology to reflect a slightly lower future earnings multiple, even as estimates for fair value and long term growth remain largely unchanged. What's in the News Puma Biotechnology has been added to the NASDAQ Biotechnology Index, increasing its visibility among biotech-focused investors (index announcement).
Narrative Update Dec 12

PBYI: 2025 Revenue Guidance Will Fail To Justify Current Optimism

Analysts have modestly adjusted their price target on Puma Biotechnology higher, now seeing slightly improved valuation support in light of stable fair value estimates and marginally lower perceived risk in the companys long term outlook. What's in the News Puma Biotechnology issued new fourth quarter 2025 guidance, projecting total revenue between $67 million and $70 million and net income of $9 million to $11 million (company guidance).
Analysis Article Dec 09

With EPS Growth And More, Puma Biotechnology (NASDAQ:PBYI) Makes An Interesting Case

Investors are often guided by the idea of discovering 'the next big thing', even if that means buying 'story stocks...
Narrative Update Nov 27

PBYI: Rising Discount Rate Will Undermine Earnings Momentum In 2025

Analysts have slightly lowered their price target for Puma Biotechnology, citing marginal revisions in key financial estimates. This resulted in a new target of $3.50 per share, which remains unchanged from the previous assessment.
Analysis Article Nov 13

Puma Biotechnology's (NASDAQ:PBYI) Shareholders May Want To Dig Deeper Than Statutory Profit

The market shrugged off Puma Biotechnology, Inc.'s ( NASDAQ:PBYI ) solid earnings report. We think that investors might...
Seeking Alpha Nov 10

Puma Biotechnology: Step By Step In Making A Transition

Summary Puma Biotechnology has been in something of a stasis for years, selling one drug with no new approvals while developing alisertib. The cash position remains strong enough to carry them through key readouts of the ALISCA trials. Two interim readouts guided in 1H 2026 will inform what is next for PBYI, and I think this has a lot of promise. Read the full article on Seeking Alpha
Narrative Update Nov 09

PBYI: Rising Discount Rate And Weak Revenue Outlook Will Pressure Earnings

Analysts have raised their price target for Puma Biotechnology from $3.00 to $3.50, citing improved revenue growth projections and stronger expected profit margins. What's in the News Puma Biotechnology issued new earnings guidance for the fourth quarter of 2025, projecting total revenue between $67 million and $70 million, and net income between $9 million and $11 million (Key Developments).
Analysis Article Oct 18

Puma Biotechnology, Inc. (NASDAQ:PBYI) Stock Catapults 26% Though Its Price And Business Still Lag The Market

Puma Biotechnology, Inc. ( NASDAQ:PBYI ) shares have continued their recent momentum with a 26% gain in the last month...
Analysis Article Sep 11

Does Puma Biotechnology (NASDAQ:PBYI) Have A Healthy Balance Sheet?

Legendary fund manager Li Lu (who Charlie Munger backed) once said, 'The biggest investment risk is not the volatility...
Analysis Article Aug 12

Puma Biotechnology, Inc. (NASDAQ:PBYI) Stock Catapults 43% Though Its Price And Business Still Lag The Market

NasdaqGS:PBYI 1 Year Share Price vs Fair Value Explore Puma Biotechnology's Fair Values from the Community and select...
Analysis Article Aug 09

We Ran A Stock Scan For Earnings Growth And Puma Biotechnology (NASDAQ:PBYI) Passed With Ease

For beginners, it can seem like a good idea (and an exciting prospect) to buy a company that tells a good story to...
Analysis Article May 20

Puma Biotechnology, Inc. (NASDAQ:PBYI) Shares Fly 25% But Investors Aren't Buying For Growth

Puma Biotechnology, Inc. ( NASDAQ:PBYI ) shareholders have had their patience rewarded with a 25% share price jump in...
Seeking Alpha Apr 11

Puma Biotechnology: Initiating Hold Rating With Limited Near-Term Upside And Uncertain Pipeline Potential

Summary Initiate coverage of Puma Biotechnology with a Hold rating due to limited near-term upside, competitive landscape, and uncertain pipeline outlook. NERLYNX adoption is hindered by side effects and competition, while alisertib is still in early development with modest expectations. Puma's cash runway may extend several years, but that could change with faltering revenues for NERLYNX, new drug additions, or other unforeseen pipeline developments. Legal issues and competitive pressures contribute to the cautious outlook, with no clear signs of growth or turnaround. Read the full article on Seeking Alpha
Analysis Article Mar 10

Puma Biotechnology, Inc. (NASDAQ:PBYI) Held Back By Insufficient Growth Even After Shares Climb 26%

Puma Biotechnology, Inc. ( NASDAQ:PBYI ) shares have had a really impressive month, gaining 26% after a shaky period...
User avatar
New Narrative Feb 09

Alisertib Trials And International NERLYNX Approvals Will Expand Market, But Single Product Dependence And Safety Concerns Could Limit Gains

Strategic collaborations and regulatory approvals in international markets are expected to drive global revenue growth and increase overall sales.
Analysis Article Jan 14

Insufficient Growth At Puma Biotechnology, Inc. (NASDAQ:PBYI) Hampers Share Price

You may think that with a price-to-sales (or "P/S") ratio of 0.6x Puma Biotechnology, Inc. ( NASDAQ:PBYI ) is...
Seeking Alpha Dec 16

Puma Biotechnology: Continuing To Push Their Aurora Kinase Story Forward

Summary Puma Biotechnology focuses on expanding neratinib sales and developing alisertib for breast and lung cancers, despite recent stock declines. Neratinib sales are stagnant, but the company remains stable financially. Alisertib shows early efficacy signals, with phase 2 trials ongoing, but its future success remains uncertain. Despite market skepticism, I maintain a "Buy" sentiment due to PBYI's favorable financial status and potential growth from alisertib. Read the full article on Seeking Alpha
Analysis Article Nov 14

Puma Biotechnology's (NASDAQ:PBYI) Performance Is Even Better Than Its Earnings Suggest

When companies post strong earnings, the stock generally performs well, just like Puma Biotechnology, Inc.'s...
Analysis Article Sep 07

Is Puma Biotechnology (NASDAQ:PBYI) A Risky Investment?

David Iben put it well when he said, 'Volatility is not a risk we care about. What we care about is avoiding the...
Analysis Article Aug 15

Lacklustre Performance Is Driving Puma Biotechnology, Inc.'s (NASDAQ:PBYI) 26% Price Drop

To the annoyance of some shareholders, Puma Biotechnology, Inc. ( NASDAQ:PBYI ) shares are down a considerable 26% in...
Analysis Article Jun 07

The Market Doesn't Like What It Sees From Puma Biotechnology, Inc.'s (NASDAQ:PBYI) Earnings Yet As Shares Tumble 25%

To the annoyance of some shareholders, Puma Biotechnology, Inc. ( NASDAQ:PBYI ) shares are down a considerable 25% in...
Analysis Article Jun 05

Here's Why We Think Puma Biotechnology (NASDAQ:PBYI) Might Deserve Your Attention Today

For beginners, it can seem like a good idea (and an exciting prospect) to buy a company that tells a good story to...

Earnings and Revenue Growth Forecasts

NasdaqGS:PBYI - Analysts future estimates and past financials data (USD Millions)
DateRevenueEarningsFree Cash FlowCash from OpAvg. No. Analysts
12/31/2028216761N/A1
12/31/20272191065N/A1
12/31/20262221569N/A1
3/31/2026227245454N/A
12/31/2025228314242N/A
9/30/2025212374343N/A
6/30/2025238484444N/A
3/31/2025233383131N/A
12/31/2024230303939N/A
9/30/2024244233434N/A
6/30/202421993333N/A
3/31/2024227153536N/A
12/31/2023236221427N/A
9/30/20232294524N/A
6/30/2023230-21131N/A
3/31/20232355-614N/A
12/31/20222280-23-16N/A
9/30/202221810-29-29N/A
6/30/2022207-34-36-36N/A
3/31/2022201-49-22-22N/A
12/31/2021253-292121N/A
9/30/2021250-482020N/A
6/30/2021255-351212N/A
3/31/2021272-271828N/A
12/31/2020225-60-91N/A
9/30/2020235-56-28N/A
6/30/2020241-42-11-1N/A
3/31/2020224-822727N/A
12/31/2019272-76N/A22N/A
9/30/2019280-95N/A28N/A
6/30/2019287-92N/A28N/A
3/31/2019284-99N/A-34N/A
12/31/2018251-114N/A-24N/A
9/30/2018202-147N/A-67N/A
6/30/2018145-210N/A-114N/A
3/31/201894-243N/A-143N/A
12/31/201728-292N/A-172N/A
9/30/20176-301N/A-178N/A
6/30/2017N/A-289N/A-158N/A
3/31/2017N/A-278N/A-143N/A
12/31/2016N/A-276N/A-142N/A
9/30/2016N/A-265N/A-134N/A
6/30/2016N/A-260N/A-136N/A
3/31/2016N/A-258N/A-139N/A
12/31/2015N/A-239N/A-154N/A
9/30/2015N/A-225N/A-140N/A

Analyst Future Growth Forecasts

Earnings vs Savings Rate: PBYI's earnings are forecast to decline over the next 3 years (-49.9% per year).

Earnings vs Market: PBYI's earnings are forecast to decline over the next 3 years (-49.9% per year).

High Growth Earnings: PBYI's earnings are forecast to decline over the next 3 years.

Revenue vs Market: PBYI's revenue is expected to decline over the next 3 years (-1.6% per year).

High Growth Revenue: PBYI's revenue is forecast to decline over the next 3 years (-1.6% per year).


Earnings per Share Growth Forecasts


Future Return on Equity

Future ROE: Insufficient data to determine if PBYI's Return on Equity is forecast to be high in 3 years time


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/20 05:30
End of Day Share Price 2026/05/20 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Puma Biotechnology, Inc. is covered by 13 analysts. 1 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Geoffrey MeachamBofA Global Research
Yigal NochomovitzCitigroup Inc
Paul ChoiGoldman Sachs