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Organogenesis Holdings Inc.NasdaqCM:ORGO Stock Report

Market Cap US$342.3m
Share Price
US$2.66
US$8.5
68.7% undervalued intrinsic discount
1Y-8.3%
7D10.4%
1D
Portfolio Value
View

Organogenesis Holdings Inc.

NasdaqCM:ORGO Stock Report

Market Cap: US$342.3m

Organogenesis Holdings (ORGO) Stock Overview

A regenerative medicine company, develops, manufactures, and commercializes products for the advanced wound care, and surgical and sports medicine markets in the United States. More details

ORGO fundamental analysis
Snowflake Score
Valuation5/6
Future Growth0/6
Past Performance0/6
Financial Health6/6
Dividends0/6

ORGO Community Fair Values

Create Narrative

See what 8 others think this stock is worth. Follow their fair value or set your own to get alerts.

Organogenesis Holdings Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Organogenesis Holdings
Historical stock prices
Current Share PriceUS$2.66
52 Week HighUS$7.08
52 Week LowUS$2.04
Beta1.31
1 Month Change13.19%
3 Month Change-32.14%
1 Year Change-8.28%
3 Year Change-29.44%
5 Year Change-85.08%
Change since IPO-80.21%

Recent News & Updates

Seeking Alpha Apr 07

Organogenesis: Clinical Win De-Risks 2026, Recovery In Sight

Summary Organogenesis Holdings Inc. is a cash-generative wound care leader trading at distressed multiples due to overestimated short-term reimbursement risks. PuraPly AM achieved statistically significant results in a randomized controlled trial for diabetic foot ulcers, strengthening ORGO’s clinical and commercial position. ORGO faces a 25–38% revenue decline in 2026 from CMS reimbursement changes, but RCT-backed evidence de-risks coverage and supports a recovery thesis into 2027. With ORGO's EV/sales at 0.7x and EV/EBITDA at 5.4x trailing, the market is discounting severe but temporary revenue pressure, offering clear re-rating upside if reimbursement stabilizes. Read the full article on Seeking Alpha

Recent updates

Seeking Alpha Apr 07

Organogenesis: Clinical Win De-Risks 2026, Recovery In Sight

Summary Organogenesis Holdings Inc. is a cash-generative wound care leader trading at distressed multiples due to overestimated short-term reimbursement risks. PuraPly AM achieved statistically significant results in a randomized controlled trial for diabetic foot ulcers, strengthening ORGO’s clinical and commercial position. ORGO faces a 25–38% revenue decline in 2026 from CMS reimbursement changes, but RCT-backed evidence de-risks coverage and supports a recovery thesis into 2027. With ORGO's EV/sales at 0.7x and EV/EBITDA at 5.4x trailing, the market is discounting severe but temporary revenue pressure, offering clear re-rating upside if reimbursement stabilizes. Read the full article on Seeking Alpha
Narrative Update Feb 19

ORGO: FDA Rolling BLA For Knee Osteoarthritis Will Support Bullish Outlook

Analysts have maintained their $8.00 price target on Organogenesis Holdings, citing updated assumptions for discount rate, revenue growth, profit margin and future P/E that they view as better aligned with the company’s current risk and earnings profile. What's in the News Organogenesis completed a planned Type B meeting with the FDA, securing confirmation to begin a rolling Biologics License Application for ReNu, with the filing expected to start before the end of December (Key Developments).
Narrative Update Feb 05

ORGO: FDA BLA Progress For Knee Osteoarthritis Will Support Bullish Outlook

Analysts have slightly trimmed their price targets on Organogenesis Holdings, citing updated assumptions that include a modestly higher discount rate, slightly stronger revenue growth and profit margin estimates, and a somewhat lower future P/E multiple. What's in the News Organogenesis Holdings reported a successful Type B meeting with the FDA that cleared the way to start a rolling Biologics License Application, or BLA, for its ReNu product, with filing planned before the end of December (Key Developments).
Narrative Update Jan 21

ORGO: FDA Rolling Submission For Knee Osteoarthritis Therapy Will Support Bullish Outlook

Analysts have nudged their price target on Organogenesis Holdings higher to US$8.00, citing slightly firmer assumptions around the discount rate, revenue growth, profit margin, and future P/E expectations. What's in the News Completed a planned Type B meeting with the FDA, receiving confirmation to initiate a rolling Biologics License Application for ReNu, targeted before the end of December (Key Developments).
Analysis Article Jan 17

The Market Doesn't Like What It Sees From Organogenesis Holdings Inc.'s (NASDAQ:ORGO) Revenues Yet As Shares Tumble 28%

Organogenesis Holdings Inc. ( NASDAQ:ORGO ) shareholders won't be pleased to see that the share price has had a very...
Analysis Article Jan 11

Is Organogenesis Holdings (NASDAQ:ORGO) In A Good Position To Invest In Growth?

Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Narrative Update Jan 06

ORGO: Regulatory Momentum For Knee Osteoarthritis Therapy Will Support Bullish Outlook

Analysts have raised their fair value estimate for Organogenesis Holdings from US$7.00 to US$8.00, citing changes in the discount rate, revenue growth assumptions, profit margin expectations and future P/E estimates as key drivers of the updated price target. What's in the News Completed a planned Type-B meeting with the FDA, with confirmation to begin a rolling Biologics License Application (BLA) for ReNu before the end of December (Key Developments).
Narrative Update Dec 18

ORGO: Upcoming Knee Osteoarthritis BLA Filing Will Drive Long Term Upside

Analysts have modestly lifted their price target on Organogenesis Holdings to 8.50 dollars from 8.50 dollars, reflecting slightly higher long term profitability and valuation assumptions despite essentially unchanged growth and fair value estimates. What's in the News Completed a planned Type B FDA meeting confirming the path to initiate a rolling Biologics License Application for ReNu for knee osteoarthritis before the end of December, which advances the regulatory strategy for this lead asset (Key Developments) Raised 2025 guidance and projected net product revenue between 500.0 million dollars and 525.0 million dollars, an increase of 4% to 9% year over year, with expected net income between 8.6 million dollars and 25.4 million dollars (Key Developments) Reported that the second Phase 3 randomized controlled trial of ReNu in knee osteoarthritis did not meet its primary endpoint for statistical significance, but showed numerical pain reduction improvements and maintained a favorable safety profile, supporting plans for an FDA BLA filing (Key Developments) Highlighted that ReNu has been evaluated in three large randomized controlled trials involving more than 1,300 patients and previously received FDA Regenerative Medicine Advanced Therapy designation for knee osteoarthritis, which reinforces its clinical and regulatory foundation (Key Developments) Valuation Changes Fair Value Estimate remained unchanged at 8.50 dollars per share, indicating a stable view of intrinsic equity value.
Narrative Update Dec 04

ORGO: Upcoming Knee Osteoarthritis FDA Filing Will Support Future Share Price Expansion

Analysts have modestly raised their price target on Organogenesis Holdings to 8.50 dollars from 7.50 dollars, citing a slightly higher assumed future price to earnings multiple that more than offsets minor adjustments to the discount rate and margin assumptions. What's in the News Raised 2025 earnings guidance, expecting net product revenue of 500 million to 525 million dollars, up 4% to 9% year over year from 482 million dollars in 2024, with projected net income between 8.6 million and 25.4 million dollars (company guidance).
Analysis Article Nov 27

Organogenesis Holdings Inc.'s (NASDAQ:ORGO) Shares Bounce 27% But Its Business Still Trails The Industry

Organogenesis Holdings Inc. ( NASDAQ:ORGO ) shares have had a really impressive month, gaining 27% after a shaky period...
Narrative Update Nov 20

ORGO: Anticipated 2025 Guidance And Promising Data Will Support Share Price Expansion

Analysts have revised their price target for Organogenesis Holdings downward from $8.00 to $7.50. This reflects a tempered outlook based on updated forecasts for revenue growth and profit margins.
Narrative Update Aug 15

CMS Reform And Capacity Expansion Will Unlock Long Term Value

With no change in key metrics such as Future P/E and Net Profit Margin, the consensus analyst price target for Organogenesis Holdings remains steady at $8.00. What's in the News Organogenesis updated full-year 2025 guidance: expects net product revenue between $480 million and $510 million (roughly flat to 6% growth) and net income (loss) ranging from a $6.4 million loss to a $16.4 million profit.
Analysis Article May 04

Organogenesis Holdings Inc. (NASDAQ:ORGO) Stock Catapults 36% Though Its Price And Business Still Lag The Industry

Despite an already strong run, Organogenesis Holdings Inc. ( NASDAQ:ORGO ) shares have been powering on, with a gain of...
User avatar
New Narrative Apr 25

LCD Delays And ReNu Progress Will Unlock Market Potential

Delay in LCDs implementation offers a chance to capitalize on demand, boosting near-term revenue and market share for key products.
Analysis Article Mar 02

There's No Escaping Organogenesis Holdings Inc.'s (NASDAQ:ORGO) Muted Revenues Despite A 69% Share Price Rise

The Organogenesis Holdings Inc. ( NASDAQ:ORGO ) share price has done very well over the last month, posting an...
Seeking Alpha Oct 15

Organogenesis: Lurking Disruption With Recovery To Follow

Summary Medicare reimbursement issues expected for certain of Organogenesis' skin substitute projects disrupting revenues in 2025. Major catalyst is expected for ORGO with BLA filing in late 2025. Liquidity is adequate and excellent potential for acquisition on expected pullbacks. Read the full article on Seeking Alpha
Analysis Article Sep 09

Why Investors Shouldn't Be Surprised By Organogenesis Holdings Inc.'s (NASDAQ:ORGO) Low P/S

Organogenesis Holdings Inc.'s ( NASDAQ:ORGO ) price-to-sales (or "P/S") ratio of 0.7x might make it look like a strong...
Analysis Article Jun 15

We Think Organogenesis Holdings Inc.'s (NASDAQ:ORGO) CEO Compensation Package Needs To Be Put Under A Microscope

Key Insights Organogenesis Holdings to hold its Annual General Meeting on 20th of June Salary of US$908.7k is part of...
Seeking Alpha Jun 10

Organogenesis Holdings: Small-Cap Biotech With Inconsistent Earnings And A Powerful Catalyst

Summary Organogenesis has two disproportionate segments, with Surgical and Sports Medicine making up a small portion of revenues. The company's pipeline candidate, ReNu, has the potential to boost Surgical and Sports Medicine revenues. In recent years, Organogenesis has generated inconsistent earnings and may not need to raise cash before launching ReNu. Read the full article on Seeking Alpha
Analysis Article May 21

Investors Can Find Comfort In Organogenesis Holdings' (NASDAQ:ORGO) Earnings Quality

Organogenesis Holdings Inc.'s ( NASDAQ:ORGO ) recent soft profit numbers didn't appear to worry shareholders, as the...
Analysis Article May 01

Shareholders Should Be Pleased With Organogenesis Holdings Inc.'s (NASDAQ:ORGO) Price

When close to half the companies in the United States have price-to-earnings ratios (or "P/E's") below 16x, you may...
Analysis Article Apr 10

Is Organogenesis Holdings (NASDAQ:ORGO) Using Too Much Debt?

Warren Buffett famously said, 'Volatility is far from synonymous with risk.' So it might be obvious that you need to...

Shareholder Returns

ORGOUS BiotechsUS Market
7D10.4%1.2%1.1%
1Y-8.3%34.6%28.7%

Return vs Industry: ORGO underperformed the US Biotechs industry which returned 34.6% over the past year.

Return vs Market: ORGO underperformed the US Market which returned 28.7% over the past year.

Price Volatility

Is ORGO's price volatile compared to industry and market?
ORGO volatility
ORGO Average Weekly Movement9.2%
Biotechs Industry Average Movement10.8%
Market Average Movement7.2%
10% most volatile stocks in US Market16.5%
10% least volatile stocks in US Market3.1%

Stable Share Price: ORGO has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: ORGO's weekly volatility (9%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
n/a854Gary Gillheeneyorganogenesis.com

Organogenesis Holdings Inc., a regenerative medicine company, develops, manufactures, and commercializes products for the advanced wound care, and surgical and sports medicine markets in the United States. Its advanced wound care products include Affinity and Novachor, which are amnion and chorion placental allografts for use in the care of chronic and acute wounds as protective barriers and extracellular matrix (ECM) scaffolds; Apligraf, a bioengineered bi-layered skin substitute for the treatment of venous leg ulcers and diabetic foot ulcers (DFU); Dermagraft, a dermal substitute grown from human dermal fibroblasts to treat DFUs; NuShield, a dehydrated placental allograft and surgical barrier to provide a protective barrier and ECM scaffold to support native healing; PuraPly Antimicrobial (AM) and PuraPly SX, which are antimicrobial barriers for the management of open wounds in surgical settings; and CYGNUS Dual, VIA Matrix, and SimpliMax are placental tissue grafts used to treat chronic and acute wounds that can be stored at room temperature. The company also provides PuraPly MZ, a micronized version of PuraPly for the management of open wounds in surgical settings; PuraForce, a bioengineered porcine collagen surgical matrix for use in soft tissue reinforcement applications; FortiShield, a biosynthetic wound matrix for use as a temporary protective covering; and TransCyte, a bioengineered tissue scaffold that promotes burn healing.

Organogenesis Holdings Inc. Fundamentals Summary

How do Organogenesis Holdings's earnings and revenue compare to its market cap?
ORGO fundamental statistics
Market capUS$342.27m
Earnings (TTM)-US$14.55m
Revenue (TTM)US$514.70m
0.7x
P/S Ratio
-23.5x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
ORGO income statement (TTM)
RevenueUS$514.70m
Cost of RevenueUS$134.39m
Gross ProfitUS$380.31m
Other ExpensesUS$394.86m
Earnings-US$14.55m

Last Reported Earnings

Mar 31, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-0.11
Gross Margin73.89%
Net Profit Margin-2.83%
Debt/Equity Ratio0%

How did ORGO perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/24 07:24
End of Day Share Price 2026/05/22 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Organogenesis Holdings Inc. is covered by 7 analysts. 1 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Michael GormanBTIG
Ross OsbornCantor Fitzgerald & Co.
Richard NewitterLeerink Partners LLC