Stock Analysis

Liquidia (LQDA): Evaluating Valuation After Positive Tyvaso Results Shift Pulmonary Treatment Landscape

Shares of Liquidia (LQDA) drew investor attention after United Therapeutics reported positive clinical results for Tyvaso in idiopathic pulmonary fibrosis. This news has direct implications for Liquidia, given the overlap in their pulmonary treatment focus.

See our latest analysis for Liquidia.

Liquidia’s share price has seen a noticeable uptick over the past quarter, buoyed by optimism around developments in the pulmonary space and investor attention following the Tyvaso trial results. While its 3-year total shareholder return stands out at just over 3%, recent momentum suggests a growing interest in the stock’s long-term potential as regulatory catalysts and sector innovations continue to unfold.

If today’s clinical advances have you thinking bigger picture, now is a great opportunity to broaden your search and discover fast growing stocks with high insider ownership

With shares still trading well below analyst price targets, is Liquidia offering an undervalued entry point right now? Or has the market already priced in its future growth prospects?

Advertisement

Price-to-Book Ratio of 127.1x: Is it justified?

At a last close of $22.43, Liquidia’s price-to-book ratio is 127.1 times, dramatically above both peer and industry averages. This premium raises critical questions about whether the current valuation stands on solid ground.

The price-to-book (P/B) ratio compares a company’s market value to its net assets, measuring what investors are willing to pay for each dollar of book value. In the pharmaceuticals sector, high P/B ratios can sometimes reflect innovation potential or bullish expectations, but they also signal a need for caution in loss-making companies.

Liquidia’s 127.1x P/B multiple is far above the US pharmaceuticals average of 2.2x and the peer group’s 8.4x mark. This significant deviation suggests the market is pricing in substantial future success, but the valuation is difficult to justify on current fundamentals. If a fair value regression ratio were available, it would offer a vital benchmark for where investor sentiment could adjust toward more reasonable levels.

See what the numbers say about this price — find out in our valuation breakdown.

Result: Price-to-Book Ratio of 127.1x (OVERVALUED)

However, slowing revenue growth or ongoing net losses could quickly challenge the bullish outlook and put investor confidence in Liquidia's elevated valuation to the test.

Find out about the key risks to this Liquidia narrative.

Another Perspective: Discounted Cash Flow Paints a Different Picture

Looking at Liquidia from another angle, the SWS DCF model estimates the fair value at $135.81, which is far above its current share price of $22.43. This approach suggests the stock is trading at an 83.5% discount to estimated fair value. Does this disconnect reveal a potential opportunity, or could it be a sign the market is skeptical about future growth?

Look into how the SWS DCF model arrives at its fair value.

LQDA Discounted Cash Flow as at Oct 2025
LQDA Discounted Cash Flow as at Oct 2025

Simply Wall St performs a discounted cash flow (DCF) on every stock in the world every day (check out Liquidia for example). We show the entire calculation in full. You can track the result in your watchlist or portfolio and be alerted when this changes, or use our stock screener to discover undervalued stocks based on their cash flows. If you save a screener we even alert you when new companies match - so you never miss a potential opportunity.

Build Your Own Liquidia Narrative

If you have a different perspective or want to dive deeper, you can analyze the data yourself and shape your own conclusions in just a few minutes, then Do it your way

A great starting point for your Liquidia research is our analysis highlighting 2 key rewards and 1 important warning sign that could impact your investment decision.

Looking for more investment ideas?

Broaden your investing potential and open doors to exciting new sectors with the Simply Wall Street Screener. You could be missing out on tomorrow’s biggest opportunities by staying in your comfort zone.

This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

New: AI Stock Screener & Alerts

Our new AI Stock Screener scans the market every day to uncover opportunities.

• Dividend Powerhouses (3%+ Yield)
• Undervalued Small Caps with Insider Buying
• High growth Tech and AI Companies

Or build your own from over 50 metrics.

Explore Now for Free

Have feedback on this article? Concerned about the content? Get in touch with us directly. Alternatively, email editorial-team@simplywallst.com