A Look at Amicus Therapeutics's Valuation After New 4-Year PROPEL Study Results

If you’ve been watching Amicus Therapeutics (FOLD) lately, you probably noticed the buzz after their recent data release. The company just unveiled fresh 4-year efficacy and safety results from its PROPEL open-label extension study, focused on cipaglucosidase alfa-atga plus miglustat for adults dealing with late-onset Pompe disease. Presented at a major medical conference, these updated findings offer a longer-term look at muscle function and patient outcomes, putting Amicus back on the radar for anyone tracking biotech opportunities.

This update feeds into a bigger story that’s been developing over the past year. While Amicus shares have slipped about 29% in that time, the past month paints a different picture: the stock is up 11%, and momentum has been even stronger over the last 3 months, showing a solid 33% increase. That kind of shift suggests renewed optimism, possibly driven by the clinical progress and how it might shape future revenue streams or risk perceptions.

The question now is whether the recent climb reflects true upside potential, or if the market has already priced in the growth story from these new results. Is there still room to run, or has the window for opportunity started to close?

Most Popular Narrative: 50.3% Undervalued

According to the most widely followed narrative, Amicus Therapeutics currently trades well below what analysts consider to be its fair value. The consensus points to significant upside potential if key growth assumptions hold true.

Expanding patient identification and improving diagnostic pathways have revealed a much larger underdiagnosed and untreated population for Fabry and Pompe diseases than previously estimated. This positions Amicus to drive sustained long-term revenue growth through increased patient penetration and global market expansion.

Curious which powerful trends could double the stock’s value? This narrative hinges on accelerated growth, wider margins, and bold profit milestones that could leave competitors scrambling. Wondering how these projections stack up against the current share price? Keep reading to uncover the full story fueling this dramatic undervaluation call.

Result: Fair Value of $16.09 (UNDERVALUED)

Have a read of the narrative in full and understand what's behind the forecasts.

However, persistent net losses and reliance on just a few products mean that any misstep or competitive shift could quickly upend these bullish projections.

Find out about the key risks to this Amicus Therapeutics narrative.

Another View: What Does the SWS DCF Model Say?

Looking at things from a different angle, our DCF model also points to Amicus being undervalued at present. This approach digs deeper into future cash flows rather than focusing on current sales. Could the true value be even further out of reach?

Look into how the SWS DCF model arrives at its fair value.

Simply Wall St performs a discounted cash flow (DCF) on every stock in the world every day (check out Amicus Therapeutics for example). We show the entire calculation in full. You can track the result in your watchlist or portfolio and be alerted when this changes, or use our stock screener to discover undervalued stocks based on their cash flows. If you save a screener we even alert you when new companies match - so you never miss a potential opportunity.

Build Your Own Amicus Therapeutics Narrative

If you have your own perspective or want to put the numbers to the test yourself, it only takes a few minutes to craft your own view. So why not Do it your way?

A good starting point is our analysis highlighting 4 key rewards investors are optimistic about regarding Amicus Therapeutics.

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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.

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