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Cytokinetics, IncorporatedNasdaqGS:CYTK Stock Report

Market Cap US$9.6b
Share Price
US$74.84
US$92.94
19.5% undervalued intrinsic discount
1Y126.5%
7D25.6%
Portfolio Value
View

Cytokinetics, Incorporated

NasdaqGS:CYTK Stock Report

Market Cap: US$9.6b

Cytokinetics (CYTK) Stock Overview

A biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and muscle inhibitors as potential treatments for debilitating diseases in the United States. More details

CYTK fundamental analysis
Snowflake Score
Valuation2/6
Future Growth2/6
Past Performance0/6
Financial Health2/6
Dividends0/6

CYTK Community Fair Values

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See what 18 others think this stock is worth. Follow their fair value or set your own to get alerts.

Cytokinetics, Incorporated Competitors

Price History & Performance

Summary of share price highs, lows and changes for Cytokinetics
Historical stock prices
Current Share PriceUS$74.84
52 Week HighUS$80.20
52 Week LowUS$29.31
Beta0.38
1 Month Change15.24%
3 Month Change24.24%
1 Year Change126.51%
3 Year Change90.77%
5 Year Change207.73%
Change since IPO-22.53%

Recent News & Updates

Recent updates

CYTK: ACACIA Trial Readout Will Drive Next Phase Of Momentum

The analyst price target for Cytokinetics has shifted higher to $92.94 from $79.56, with analysts pointing to stronger modeled revenue growth, a higher future P/E assumption tied to growing interest in Myqorzo and ACACIA trial catalysts, as well as updated discount rate and margin forecasts. Analyst Commentary Recent research updates cluster around the same core themes, with most activity tied to reactions to Myqorzo approval for obstructive hypertrophic cardiomyopathy, expectations for the ACACIA non obstructive HCM trial, and tweaks to long term loss and margin forecasts.

CYTK: Future Returns Will Hinge On HCM Launch And ACACIA Trial Outcome

The analyst price target for Cytokinetics is now set at $67.00. This level is supported by analysts highlighting early Myqorzo launch traction in obstructive hypertrophic cardiomyopathy, growing focus on upcoming non obstructive HCM data, and updated assumptions around expenses and interest income.

CYTK: Future Returns Will Depend On HCM Launch And ACACIA Outcome

Cytokinetics' fair value estimate has been revised to $67 from $61, reflecting analysts' higher price targets tied to early Myqorzo launch signals and the potential impact of upcoming ACACIA non obstructive HCM data. Analyst Commentary Recent Street research on Cytokinetics has centered on two main themes: Myqorzo's early launch trends in obstructive hypertrophic cardiomyopathy and the upcoming ACACIA readout in non obstructive HCM.

CYTK: Upcoming ACACIA nHCM Readout Will Drive 2026 Repricing Potential

Analysts have raised their average price targets for Cytokinetics, citing updated views on the ACACIA nHCM trial, early MYQORZO launch progress, and revised loss and expense assumptions. Together, these factors support a slightly higher fair value estimate of about $123 per share.

CYTK: Future Returns Will Depend On HCM Data And Launch Execution

Analysts have lifted their average price targets on Cytokinetics by several dollars into a $67 to $101 range, citing Q4 updates, early MYQORZO launch traction in obstructive hypertrophic cardiomyopathy, and expectations around upcoming ACACIA trial data in both obstructive and non obstructive HCM. Analyst Commentary Across recent research updates, analysts have been adjusting their models and views on Cytokinetics around Q4 results, the early MYQORZO launch in obstructive hypertrophic cardiomyopathy, and expectations for the ACACIA program in both obstructive and non obstructive HCM.

CYTK: Fair Value Reset Will Hinge On Execution Of Commercial Transition

The analyst fair value estimate for Cytokinetics has moved to $61 from $55. This change reflects updated views from recent Street research that highlight revised revenue growth, profit margin, and P/E assumptions following a series of price target increases across several firms.

CYTK: 2026 HCM Launch And Cost Discipline Will Shape Repricing Potential

Analysts have nudged their fair value target for Cytokinetics higher from about US$120 to roughly US$122 per share, reflecting updated revenue, margin and P/E assumptions following a series of recent price target increases and Overweight or Outperform views across several firms. Analyst Commentary Recent Street research has largely leaned constructive on Cytokinetics, with several bullish analysts revisiting their models and price targets around key pipeline and financial milestones.

Need To Know: The Consensus Just Cut Its Cytokinetics, Incorporated (NASDAQ:CYTK) Estimates For 2026

Jan 27
Need To Know: The Consensus Just Cut Its Cytokinetics, Incorporated (NASDAQ:CYTK) Estimates For 2026

CYTK: Anticipated 2026 HCM Launch Will Drive Repricing Potential

Narrative Update on Cytokinetics The analyst price target for Cytokinetics has been nudged higher in line with a modest fair value increase to about $120.25, as analysts factor in updated revenue and expense modeling around the potential 2026 launch of aficamten and continued interest in U.S. small to mid cap biotech names. Analyst Commentary Recent research updates around Cytokinetics center on recalibrated price targets and refreshed modeling for aficamten and operating expenses, as analysts refine their views ahead of a potential 2026 commercial launch.

CYTK: Aficamten Launch Path And Cash Outlook Will Drive Repricing

Analysts have lifted their price targets on Cytokinetics, with recent moves such as RBC's increase to US$87 and BofA's incremental raises to US$63. These changes reflect updated modeling on operating expenses, revenue assumptions around the anticipated 2026 aficamten launch, and revised net cash forecasts.

Cytokinetics: Small Label Differences With Big Commercial Stakes

Dec 22

CYTK: Elevated Expectations For 2026 Launch Will Likely Prove Difficult To Sustain

The analyst price target for Cytokinetics has been raised from $41.00 to $55.00 as analysts factor in stronger aficamten launch expectations, higher long term revenue growth and margin assumptions, and updated operating expense forecasts informed by recent Street research. Analyst Commentary Recent Street research on Cytokinetics reflects a constructive but increasingly nuanced outlook as the aficamten launch approaches.

CYTK: Momentum Will Build Ahead Of Late Cycle FDA Decision

Analysts have nudged their blended price target for Cytokinetics modestly higher, with our fair value estimate increasing from about $78.44 to $79.56. Updated models reflect stronger long term aficamten launch dynamics, refined operating expense assumptions, and incremental confidence around regulatory and commercial execution.

CYTK: Momentum Will Build Ahead Of Anticipated FDA Decision Next Year

Analysts have modestly raised their price targets for Cytokinetics, with updated forecasts supported by expectations for robust aficamten launch dynamics, improved projected revenue growth, and refined operating expense assumptions. This has led to an increase in fair value from $76.67 to $78.44 per share.

CYTK: Strong Cardiology Data Will Drive Momentum Ahead Of December 2025 FDA Decision

Analysts have modestly raised their price target for Cytokinetics, increasing it by nearly $1 to approximately $76.67. They cite ongoing favorable feedback on aficamten from recent medical meetings and firm research updates.

Analyst Commentary Highlights Shifting Sentiment on Cytokinetics Amid Aficamten Progress and Valuation Changes

Analysts have raised their average price target for Cytokinetics by approximately $1.42 to $75.83. This reflects increased confidence in aficamten's upcoming launch and updated forecasts following positive regulatory and clinical developments.

Precision Medicine And Late-stage Trials Will Expand Global Reach

Cytokinetics’ consensus price target was modestly raised to $74.41, as strong MAPLE trial data for aficamten de-risked its profile, reinforced first-line oHCM potential, and highlighted underappreciated pipeline optionality, all outweighing near-term market adoption headwinds. Analyst Commentary Bullish analysts highlighted strong MAPLE trial data for aficamten presented at ESC, reinforcing confidence in its clinical value and de-risked, best-in-disease positioning for oHCM.

Precision Medicine And Late-stage Trials Will Expand Global Reach

Upward revisions in analyst price targets for Cytokinetics reflect increased confidence in aficamten’s strong Phase 3 data, anticipated favorable FDA outcomes, and expanded commercial prospects, partially offset by concerns over possible REMS limitations and launch pacing, resulting in a higher consensus price target of $73.21. Analyst Commentary Bullish analysts highlight strong Phase 3 MAPLE-HCM and extension study data for aficamten, citing de-risked profile and high efficacy/safety, increasing their confidence ahead of regulatory decisions.
User avatar

Precision Medicine And Late-stage Trials Will Expand Global Reach

Successful late-stage clinical trials, commercial readiness, and diversification in products position the company for strong growth and reduced dependence on a single therapy.

The Cytokinetics, Incorporated (NASDAQ:CYTK) Analysts Have Been Trimming Their Sales Forecasts

May 20
The Cytokinetics, Incorporated (NASDAQ:CYTK) Analysts Have Been Trimming Their Sales Forecasts

Cytokinetics Nears Approval: 'Buy' The New Potential Cardiology Franchise With Aficamten

Mar 16

Cytokinetics Aligns For U.S. Launch Amid HCM Market Evolution

Dec 31

Cytokinetics: On The Cusp Of Commercialization

Nov 14

Shareholder Returns

CYTKUS BiotechsUS Market
7D25.6%0.8%1.8%
1Y126.5%39.2%29.8%

Return vs Industry: CYTK exceeded the US Biotechs industry which returned 39.2% over the past year.

Return vs Market: CYTK exceeded the US Market which returned 29.8% over the past year.

Price Volatility

Is CYTK's price volatile compared to industry and market?
CYTK volatility
CYTK Average Weekly Movement7.6%
Biotechs Industry Average Movement10.6%
Market Average Movement7.1%
10% most volatile stocks in US Market16.1%
10% least volatile stocks in US Market3.2%

Stable Share Price: CYTK has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: CYTK's weekly volatility (8%) has been stable over the past year.

About the Company

FoundedEmployeesCEOWebsite
1997673Robert Blumwww.cytokinetics.com

Cytokinetics, Incorporated, a biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and muscle inhibitors as potential treatments for debilitating diseases in the United States. The company markets MYQORZO, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of symptomatic oHCM. It also develops Aficamten, a novel, oral, and small molecule cardiac myosin inhibitor for the treatment of HCM; and omecamtiv mecarbil, a potential treatment across the continuum of care in heart failure with severely reduced ejection fraction.

Cytokinetics, Incorporated Fundamentals Summary

How do Cytokinetics's earnings and revenue compare to its market cap?
CYTK fundamental statistics
Market capUS$9.59b
Earnings (TTM)-US$829.61m
Revenue (TTM)US$105.82m
88.0x
P/S Ratio
-11.2x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
CYTK income statement (TTM)
RevenueUS$105.82m
Cost of RevenueUS$416.19m
Gross Profit-US$310.37m
Other ExpensesUS$519.24m
Earnings-US$829.61m

Last Reported Earnings

Mar 31, 2026

Next Earnings Date

n/a

Earnings per share (EPS)-6.67
Gross Margin-293.31%
Net Profit Margin-784.02%
Debt/Equity Ratio-144.2%

How did CYTK perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/06 21:38
End of Day Share Price 2026/05/06 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Cytokinetics, Incorporated is covered by 36 analysts. 17 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Hang HuBarclays
Carter GouldBarclays
Huidong WangBarclays