Cytokinetics, Incorporated

NasdaqGS:CYTK Stock Report

Market Cap: US$10.4b

Cytokinetics Past Earnings Performance

Past criteria checks 0/6

Cytokinetics's earnings have been declining at an average annual rate of -28.4%, while the Biotechs industry saw earnings growing at 33.8% annually. Revenues have been declining at an average rate of 5.5% per year.

Key information

-28.44%

Earnings growth rate

-19.04%

EPS growth rate

Biotechs Industry Growth17.04%
Revenue growth rate-5.50%
Return on equityn/a
Net Margin-784.02%
Last Earnings Update31 Mar 2026

Recent past performance updates

Recent updates

Analysis Article May 17

Need To Know: Analysts Are Much More Bullish On Cytokinetics, Incorporated (NASDAQ:CYTK) Revenues

Shareholders in Cytokinetics, Incorporated ( NASDAQ:CYTK ) may be thrilled to learn that the analysts have just...
Narrative Update May 14

CYTK: Future Returns Will Depend On HCM Launch And ACACIA Readout

Analysts have raised their average price target for Cytokinetics by about $5, citing a mix of updated trial expectations, improved projected profit margins, and adjustments to long term valuation assumptions. Analyst Commentary Recent research updates highlight a generally constructive stance on Cytokinetics, with several large firms lifting their price targets following product approval milestones, early launch indicators for Myqorzo in obstructive hypertrophic cardiomyopathy, and upcoming Phase 3 readouts in non obstructive disease.
Seeking Alpha May 10

Cytokinetics: Aficamten Has Momentum, But The Stock Is Too Expensive (Rating Downgrade)

Summary CYTK has begun its US launch of Myqorzo. So far, its early prescribing demand seems promising, and they’re moving towards its full commercial ramp. Additionally, aficamten recently met both primary endpoints in Phase 3 ACACIA-HCM for non-obstructive HCM. Similarly, CYTK’s MAPLE-HCM sNDA has been accepted, with a November 2026 PDUFA date. CYTK’s balance sheet also appears quite liquid today. After their recent equity offering, I estimate they now have a comfortable cash runway. Unfortunately, I feel CYTK’s valuation is now much more expensive than when I first covered it. So, ideally, I think you should wait for a dip before adding more shares. Read the full article on Seeking Alpha
Analysis Article May 07

Earnings Update: Cytokinetics, Incorporated (NASDAQ:CYTK) Just Reported And Analysts Are Boosting Their Estimates

The investors in Cytokinetics, Incorporated 's ( NASDAQ:CYTK ) will be rubbing their hands together with glee today...
Narrative Update Apr 29

CYTK: ACACIA Trial Readout Will Drive Next Phase Of Momentum

The analyst price target for Cytokinetics has shifted higher to $92.94 from $79.56, with analysts pointing to stronger modeled revenue growth, a higher future P/E assumption tied to growing interest in Myqorzo and ACACIA trial catalysts, as well as updated discount rate and margin forecasts. Analyst Commentary Recent research updates cluster around the same core themes, with most activity tied to reactions to Myqorzo approval for obstructive hypertrophic cardiomyopathy, expectations for the ACACIA non obstructive HCM trial, and tweaks to long term loss and margin forecasts.
Narrative Update Apr 14

CYTK: Future Returns Will Hinge On HCM Launch And ACACIA Trial Outcome

The analyst price target for Cytokinetics is now set at $67.00. This level is supported by analysts highlighting early Myqorzo launch traction in obstructive hypertrophic cardiomyopathy, growing focus on upcoming non obstructive HCM data, and updated assumptions around expenses and interest income.
Narrative Update Mar 31

CYTK: Future Returns Will Depend On HCM Launch And ACACIA Outcome

Cytokinetics' fair value estimate has been revised to $67 from $61, reflecting analysts' higher price targets tied to early Myqorzo launch signals and the potential impact of upcoming ACACIA non obstructive HCM data. Analyst Commentary Recent Street research on Cytokinetics has centered on two main themes: Myqorzo's early launch trends in obstructive hypertrophic cardiomyopathy and the upcoming ACACIA readout in non obstructive HCM.
Narrative Update Mar 17

CYTK: Upcoming ACACIA nHCM Readout Will Drive 2026 Repricing Potential

Analysts have raised their average price targets for Cytokinetics, citing updated views on the ACACIA nHCM trial, early MYQORZO launch progress, and revised loss and expense assumptions. Together, these factors support a slightly higher fair value estimate of about $123 per share.
Narrative Update Mar 03

CYTK: Future Returns Will Depend On HCM Data And Launch Execution

Analysts have lifted their average price targets on Cytokinetics by several dollars into a $67 to $101 range, citing Q4 updates, early MYQORZO launch traction in obstructive hypertrophic cardiomyopathy, and expectations around upcoming ACACIA trial data in both obstructive and non obstructive HCM. Analyst Commentary Across recent research updates, analysts have been adjusting their models and views on Cytokinetics around Q4 results, the early MYQORZO launch in obstructive hypertrophic cardiomyopathy, and expectations for the ACACIA program in both obstructive and non obstructive HCM.
Narrative Update Feb 17

CYTK: Fair Value Reset Will Hinge On Execution Of Commercial Transition

The analyst fair value estimate for Cytokinetics has moved to $61 from $55. This change reflects updated views from recent Street research that highlight revised revenue growth, profit margin, and P/E assumptions following a series of price target increases across several firms.
Narrative Update Feb 03

CYTK: 2026 HCM Launch And Cost Discipline Will Shape Repricing Potential

Analysts have nudged their fair value target for Cytokinetics higher from about US$120 to roughly US$122 per share, reflecting updated revenue, margin and P/E assumptions following a series of recent price target increases and Overweight or Outperform views across several firms. Analyst Commentary Recent Street research has largely leaned constructive on Cytokinetics, with several bullish analysts revisiting their models and price targets around key pipeline and financial milestones.
Analysis Article Jan 27

Need To Know: The Consensus Just Cut Its Cytokinetics, Incorporated (NASDAQ:CYTK) Estimates For 2026

Market forces rained on the parade of Cytokinetics, Incorporated ( NASDAQ:CYTK ) shareholders today, when the analysts...
Narrative Update Jan 19

CYTK: Anticipated 2026 HCM Launch Will Drive Repricing Potential

Narrative Update on Cytokinetics The analyst price target for Cytokinetics has been nudged higher in line with a modest fair value increase to about $120.25, as analysts factor in updated revenue and expense modeling around the potential 2026 launch of aficamten and continued interest in U.S. small to mid cap biotech names. Analyst Commentary Recent research updates around Cytokinetics center on recalibrated price targets and refreshed modeling for aficamten and operating expenses, as analysts refine their views ahead of a potential 2026 commercial launch.
Narrative Update Jan 05

CYTK: Aficamten Launch Path And Cash Outlook Will Drive Repricing

Analysts have lifted their price targets on Cytokinetics, with recent moves such as RBC's increase to US$87 and BofA's incremental raises to US$63. These changes reflect updated modeling on operating expenses, revenue assumptions around the anticipated 2026 aficamten launch, and revised net cash forecasts.
Narrative Update Dec 17

CYTK: Elevated Expectations For 2026 Launch Will Likely Prove Difficult To Sustain

The analyst price target for Cytokinetics has been raised from $41.00 to $55.00 as analysts factor in stronger aficamten launch expectations, higher long term revenue growth and margin assumptions, and updated operating expense forecasts informed by recent Street research. Analyst Commentary Recent Street research on Cytokinetics reflects a constructive but increasingly nuanced outlook as the aficamten launch approaches.
Narrative Update Dec 03

CYTK: Momentum Will Build Ahead Of Late Cycle FDA Decision

Analysts have nudged their blended price target for Cytokinetics modestly higher, with our fair value estimate increasing from about $78.44 to $79.56. Updated models reflect stronger long term aficamten launch dynamics, refined operating expense assumptions, and incremental confidence around regulatory and commercial execution.
Narrative Update Nov 19

CYTK: Momentum Will Build Ahead Of Anticipated FDA Decision Next Year

Analysts have modestly raised their price targets for Cytokinetics, with updated forecasts supported by expectations for robust aficamten launch dynamics, improved projected revenue growth, and refined operating expense assumptions. This has led to an increase in fair value from $76.67 to $78.44 per share.
Narrative Update Nov 05

CYTK: Strong Cardiology Data Will Drive Momentum Ahead Of December 2025 FDA Decision

Analysts have modestly raised their price target for Cytokinetics, increasing it by nearly $1 to approximately $76.67. They cite ongoing favorable feedback on aficamten from recent medical meetings and firm research updates.
Narrative Update Oct 22

Analyst Commentary Highlights Shifting Sentiment on Cytokinetics Amid Aficamten Progress and Valuation Changes

Analysts have raised their average price target for Cytokinetics by approximately $1.42 to $75.83. This reflects increased confidence in aficamten's upcoming launch and updated forecasts following positive regulatory and clinical developments.
Narrative Update Sep 18

Precision Medicine And Late-stage Trials Will Expand Global Reach

Cytokinetics’ consensus price target was modestly raised to $74.41, as strong MAPLE trial data for aficamten de-risked its profile, reinforced first-line oHCM potential, and highlighted underappreciated pipeline optionality, all outweighing near-term market adoption headwinds. Analyst Commentary Bullish analysts highlighted strong MAPLE trial data for aficamten presented at ESC, reinforcing confidence in its clinical value and de-risked, best-in-disease positioning for oHCM.
Narrative Update Sep 03

Precision Medicine And Late-stage Trials Will Expand Global Reach

Upward revisions in analyst price targets for Cytokinetics reflect increased confidence in aficamten’s strong Phase 3 data, anticipated favorable FDA outcomes, and expanded commercial prospects, partially offset by concerns over possible REMS limitations and launch pacing, resulting in a higher consensus price target of $73.21. Analyst Commentary Bullish analysts highlight strong Phase 3 MAPLE-HCM and extension study data for aficamten, citing de-risked profile and high efficacy/safety, increasing their confidence ahead of regulatory decisions.
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New Narrative Aug 10

Precision Medicine And Late-stage Trials Will Expand Global Reach

Successful late-stage clinical trials, commercial readiness, and diversification in products position the company for strong growth and reduced dependence on a single therapy.
Seeking Alpha Mar 16

Cytokinetics Nears Approval: 'Buy' The New Potential Cardiology Franchise With Aficamten

Summary Cytokinetics is now rapidly moving into commercialization efforts with Aficamten. If all goes well, it could be approved by September 2025. Aficamten had favorable Phase 3 data, so it could have solid competitive prospects if approved, possibly with better safety and simpler dosing. Although CYTK looks a bit pricey today, Aficamten’s $10 billion TAM by 2035 makes CYTK’s valuation much more reasonable. Still, regulatory and competitive risks remain, but I think CYTK’s rollout strategy and broader franchise ambitions outweigh the downside risks. Overall, I believe CYTK is a great long-term “Buy” due to Aficamten’s potential as an emerging blockbuster drug in cardiology. Read the full article on Seeking Alpha
Seeking Alpha Dec 31

Cytokinetics Aligns For U.S. Launch Amid HCM Market Evolution

Summary Cytokinetics is advancing aficamten, a potential competitor to Camzyos, targeting hypertrophic cardiomyopathy (HCM). Strategic licensing deals with Sanofi and Bayer secure resources and focus US commercialization. Clinical trials aim to expand aficamten's utility, including first-line and pediatric indications. Financials are strong, with $1.3 billion in cash, but liabilities create long-term risks. While aficamten shows promise, competition from Bristol Myers and financial risks suggest a tempered "Buy" recommendation. Read the full article on Seeking Alpha

Revenue & Expenses Breakdown

How Cytokinetics makes and spends money. Based on latest reported earnings, on an LTM basis.


Earnings and Revenue History

NasdaqGS:CYTK Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
31 Mar 26106-8303321
31 Dec 2588-7852840
30 Sep 2587-7522552
30 Jun 2586-6062422
31 Mar 2519-6152272
31 Dec 2418-5902150
30 Sep 243-5761970
30 Jun 243-5451810
31 Mar 244-5311690
31 Dec 238-5261740
30 Sep 238-5271830
30 Jun 2310-5401920
31 Mar 2398-4311950
31 Dec 2295-3891780
30 Sep 22148-2821580
30 Jun 22151-2161360
31 Mar 2265-2581140
31 Dec 2170-215970
30 Sep 2122-229770
30 Jun 2158-156630
31 Mar 2159-135560
31 Dec 2056-127530
30 Sep 2054-114490
30 Jun 2019-140470
31 Mar 2022-132430
31 Dec 1927-122400
30 Sep 1931-118370
30 Jun 1936-110330
31 Mar 1935-105310
31 Dec 1832-106310
30 Sep 1822-120340
30 Jun 1818-131370
31 Mar 1814-132380
31 Dec 1713-128360
30 Sep 1747-80330
30 Jun 1799-14300
31 Mar 171023290
31 Dec 1610616280
30 Sep 16830270
30 Jun 1632-42250
31 Mar 1633-41220
31 Dec 1529-38200
30 Sep 1541-20190
30 Jun 1542-17170

Quality Earnings: CYTK is currently unprofitable.

Growing Profit Margin: CYTK is currently unprofitable.


Free Cash Flow vs Earnings Analysis


Past Earnings Growth Analysis

Earnings Trend: CYTK is unprofitable, and losses have increased over the past 5 years at a rate of 28.4% per year.

Accelerating Growth: Unable to compare CYTK's earnings growth over the past year to its 5-year average as it is currently unprofitable

Earnings vs Industry: CYTK is unprofitable, making it difficult to compare its past year earnings growth to the Biotechs industry (43%).


Return on Equity

High ROE: CYTK's liabilities exceed its assets, so it is difficult to calculate its Return on Equity.


Return on Assets


Return on Capital Employed


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/05/20 12:34
End of Day Share Price 2026/05/20 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

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Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Cytokinetics, Incorporated is covered by 37 analysts. 19 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Carter GouldBarclays
Emily FieldBarclays
Huidong WangBarclays