Agenus Inc.

NasdaqCM:AGEN Stock Report

Market Cap: US$145.3m

Agenus Future Growth

Future criteria checks 0/6

Agenus's earnings are forecast to decline at 48.4% per annum while its annual revenue is expected to grow at 0.7% per year. EPS is expected to decline by 67% per annum.

Key information

-48.4%

Earnings growth rate

-67.02%

EPS growth rate

Biotechs earnings growth25.1%
Revenue growth rate0.7%
Future return on equityn/a
Analyst coverage

Low

Last updated22 May 2026

Recent future growth updates

Analysis Article May 09

Analysts Have Lowered Expectations For Agenus Inc. (NASDAQ:AGEN) After Its Latest Results

Shareholders might have noticed that Agenus Inc. ( NASDAQ:AGEN ) filed its quarterly result this time last week. The...

Recent updates

Narrative Update Jun 23

AGEN: Late-Stage Cancer Pipeline And Access Programs Will Drive Future Upside

Analysts have revised their price target on Agenus to reflect a lower assumed future P/E of 24.80x, down from 34.01x, alongside updated views on revenue growth and profit margins that together temper growth expectations while assuming a stronger profitability profile. What’s in the News for Agenus Agenus is advancing its botensilimab plus balstilimab program with new retrospective data using Noetik’s AI based TARIO-2 model to analyze routine H&E tumor images and identify spatial tumor microenvironment patterns linked with clinical outcomes in solid tumors, including microsatellite stable metastatic colorectal cancer, ovarian cancer, and sarcomas, with results to be presented at the 2026 ASCO Annual Meeting.
Narrative Update Jun 08

AGEN: Phase 3 Colorectal Cancer Trial Will Support Bullish Reassessment

Analyst price targets for Agenus have been reaffirmed at $15.50, with modest adjustments to the discount rate, revenue growth assumptions, profit margin and forward P/E reflecting analysts' updated view of the stock's risk profile and earnings potential. What's in the News Agenus is advancing its botensilimab plus balstilimab (BOT+BAL) program with multiple data disclosures, including new Phase 2 results in advanced cutaneous melanoma and published Phase 1b data in treatment refractory hepatocellular carcinoma.
Narrative Update May 24

AGEN: Phase 3 Colorectal Cancer Trial Will Drive Bullish Reassessment

Analysts now set a higher price target for Agenus, moving their fair value estimate from $12.33 to $15.50, citing updated assumptions around discount rates, revenue growth, profit margins, and future P/E levels. What's in the News Phase 2 data from the C-800-23 study in advanced cutaneous melanoma showed a 22% confirmed objective response rate for botensilimab plus balstilimab, with median overall survival of 16.6 months and a 42% 2 year overall survival rate in the overall cohort, and no treatment related deaths reported (Key Developments).
Narrative Update May 04

AGEN: Late Stage Cancer Data And Access Programs Will Drive Future Upside

Analysts have reduced their price targets on Agenus by $8.00 after updating their assumptions for revenue growth, profit margins, and future P/E levels to reflect a more conservative view of the stock’s valuation inputs. What's in the News Agenus is presenting four botensilimab and balstilimab abstracts at the 2026 ASCO Annual Meeting, including first Phase 2 data in advanced cutaneous melanoma and a trial-in-progress update on the Phase 3 CO.33/BATTMAN colorectal cancer study (Key Developments).
Narrative Update Apr 20

AGEN: Late Stage Gastrointestinal Cancer Data Will Drive Future Upside

Analysts have nudged their price target on Agenus higher to $8.00, reflecting updated assumptions around discount rates, revenue trends, profit margins, and future P/E expectations. What's in the News Agenus reported Phase II data from a Memorial Sloan Kettering trial combining botensilimab, balstilimab, agenT-797, ramucirumab, and paclitaxel in advanced PD-1 refractory gastroesophageal adenocarcinoma, with a 77% disease control rate in 17 patients and a subset showing survival beyond 20 months (AACR Annual Meeting 2026).
Narrative Update Apr 04

AGEN: Expanded Late-Stage Trials And Access Programs Will Drive Future Upside

Analysts have raised their price target on Agenus from $6.00 to $8.00. This reflects updated assumptions around fair value, discount rate, revenue growth, profit margin, and a higher future P/E of 28.67x compared with 19.01x previously.
Narrative Update Aug 17

Advanced Immuno-Oncology Therapies Will Reshape Future Cancer Care

The notable upward revision in Agenus’s fair value target is primarily driven by significant improvements in net profit margin and a modest increase in forecasted revenue growth, resulting in a consensus analyst price target increase from $11.00 to $12.33. What's in the News Agenus' botensilimab and balstilimab immunotherapy programs continue to show promising clinical progress, with new survival data and presentations at major oncology congresses, including a 42% two-year survival rate and 21-month median OS in immunotherapy-resistant MSS metastatic colorectal cancer.
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New Narrative Apr 08

BOT/BAL Trials And Cost Reductions Will Shape Future Advances

Strategic cost reduction and asset monetization aim to strengthen financials and fund key projects like BOT/BAL, enhancing potential revenues and earnings.
Seeking Alpha Jul 24

Agenus: Novel Drugs That Just Are Not Novel

Summary Agenus is a small biotech company focused on developing cancer treatments, with a history of poor stock performance and financial struggles. The company's primary assets in its pipeline are Botensilimab and Balstilimab, which have shown limited efficacy in pre-clinical and clinical trials. Recent FDA meeting and phase 2 metastatic colorectal cancer data plummeted AGEN stock 60%, due to discouragement to file for accelerated approval. Further funding is likely to be required soon, considering high cash burn rates and the upcoming phase 3 trial in mCRC. Read the full article on Seeking Alpha
Analysis Article May 21

There's No Escaping Agenus Inc.'s (NASDAQ:AGEN) Muted Revenues Despite A 102% Share Price Rise

Agenus Inc. ( NASDAQ:AGEN ) shareholders are no doubt pleased to see that the share price has bounced 102% in the last...
Analysis Article May 09

Analysts Have Lowered Expectations For Agenus Inc. (NASDAQ:AGEN) After Its Latest Results

Shareholders might have noticed that Agenus Inc. ( NASDAQ:AGEN ) filed its quarterly result this time last week. The...
Analysis Article Mar 29

Benign Growth For Agenus Inc. (NASDAQ:AGEN) Underpins Stock's 25% Plummet

Agenus Inc. ( NASDAQ:AGEN ) shareholders that were waiting for something to happen have been dealt a blow with a 25...
Seeking Alpha Jan 18

Agenus: 2024 May Finally Be The Year For A Major Turnaround

Summary Agenus is a beaten-down immuno-oncology biotech stock that has not participated in the recent biotech rally despite a promising pipeline and multiple partnerships. The company's lead asset, botensilimab (+/- balstilimab), has shown promising results in various advanced solid tumors (colorectal, pancreatic, melanoma, NSCLC, sarcomas, ovarian). A BLA is planned in mid-2024 for accelerated approval in metastatic colorectal cancer with potential for subsequent label expansion to earlier lines. Potential new partnerships are also being evaluated. Cash runway is a concern but planned transactions (sale of 2 assets and monetization of milestones/royalties from partnered programs) in 1H 2024 are expected to considerably extend cash runway. Considering AGEN's track record I am confident about these transactions. Read the full article on Seeking Alpha
Analysis Article Dec 22

Improved Revenues Required Before Agenus Inc. (NASDAQ:AGEN) Shares Find Their Feet

Agenus Inc.'s ( NASDAQ:AGEN ) price-to-sales (or "P/S") ratio of 2.9x might make it look like a strong buy right now...
Analysis Article Nov 09

News Flash: Analysts Just Made A Huge Upgrade To Their Agenus Inc. (NASDAQ:AGEN) Forecasts

Agenus Inc. ( NASDAQ:AGEN ) shareholders will have a reason to smile today, with the analysts making substantial...

Earnings and Revenue Growth Forecasts

NasdaqCM:AGEN - Analysts future estimates and past financials data (USD Millions)
DateRevenueEarningsFree Cash FlowCash from OpAvg. No. Analysts
12/31/2028118-37N/AN/A2
12/31/2027131-10N/AN/A2
12/31/202618546N/AN/A2
3/31/202612464-88-88N/A
12/31/20251140-77-77N/A
9/30/2025107-35-89-89N/A
6/30/2025102-166-128-128N/A
3/31/2025100-191-146-146N/A
12/31/2024103-227-159-158N/A
9/30/2024160-228-171-170N/A
6/30/2024160-224-186-182N/A
3/31/2024161-240-212-204N/A
12/31/2023156-246-234-224N/A
9/30/2023101-271-255-231N/A
6/30/202399-263-234-198N/A
3/31/202395-240-232-182N/A
12/31/202298-220-228-175N/A
9/30/202290-215-199-151N/A
6/30/202232018-4213N/A
3/31/2022310-19-380N/A
12/31/2021296-24-2410N/A
9/30/20213074-28-3N/A
6/30/202169-226-170-166N/A
3/31/202185-190-150-147N/A
12/31/202088-181-143-139N/A
9/30/202091-174-139-135N/A
6/30/202097-168-135-131N/A
3/31/202085-171-134-130N/A
12/31/2019150-108N/A-19N/A
9/30/2019122-126N/A-23N/A
6/30/2019115-113N/A-19N/A
3/31/2019115-87N/A-14N/A
12/31/201837-160N/A-131N/A
9/30/201839-147N/A-121N/A
6/30/201829-151N/A-123N/A
3/31/201818-158N/A-120N/A
12/31/201743-121N/A-94N/A
9/30/201740-112N/A-84N/A
6/30/201741-116N/A-82N/A
3/31/201744-113N/A-73N/A
12/31/201623-127N/A-80N/A
9/30/201625-117N/A-83N/A
6/30/201627-89N/A-78N/A
3/31/201627-101N/A-72N/A
12/31/201525-88N/A-47N/A
9/30/201519-98N/A-38N/A

Analyst Future Growth Forecasts

Earnings vs Savings Rate: AGEN's earnings are forecast to decline over the next 3 years (-48.4% per year).

Earnings vs Market: AGEN's earnings are forecast to decline over the next 3 years (-48.4% per year).

High Growth Earnings: AGEN's earnings are forecast to decline over the next 3 years.

Revenue vs Market: AGEN's revenue (0.7% per year) is forecast to grow slower than the US market (12.7% per year).

High Growth Revenue: AGEN's revenue (0.7% per year) is forecast to grow slower than 20% per year.


Earnings per Share Growth Forecasts


Future Return on Equity

Future ROE: Insufficient data to determine if AGEN's Return on Equity is forecast to be high in 3 years time


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/07/05 06:28
End of Day Share Price 2026/07/02 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Agenus Inc. is covered by 7 analysts. 2 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Mayank MamtaniB. Riley Securities, Inc.
Michael KingCitizens JMP Securities, LLC
Emily BodnarH.C. Wainwright & Co.