Agenus Inc.

NasdaqCM:AGEN Stock Report

Market Cap: US$208.6m

Agenus Past Earnings Performance

Past criteria checks 2/6

Agenus has been growing earnings at an average annual rate of 3.2%, while the Biotechs industry saw earnings growing at 37.6% annually. Revenues have been declining at an average rate of 13.3% per year.

Key information

3.20%

Earnings growth rate

16.98%

EPS growth rate

Biotechs Industry Growth17.04%
Revenue growth rate-13.28%
Return on equityn/a
Net Margin51.98%
Last Earnings Update31 Mar 2026

Recent past performance updates

Recent updates

Narrative Update Jul 13

AGEN: Neoadjuvant Colorectal Cancer Focus And Funding Will Drive Bullish Reassessment

Agenus' analyst price target has been reset from $15.50 to $30.00. Analysts point to the company's refocus on botensilimab and balstilimab in neoadjuvant microsatellite stable colorectal cancer, as well as the recently announced $340.0m private placement, as key drivers of their updated view.
Narrative Update Jun 23

AGEN: Late-Stage Cancer Pipeline And Access Programs Will Drive Future Upside

Analysts have revised their price target on Agenus to reflect a lower assumed future P/E of 24.80x, down from 34.01x, alongside updated views on revenue growth and profit margins that together temper growth expectations while assuming a stronger profitability profile. What’s in the News for Agenus Agenus is advancing its botensilimab plus balstilimab program with new retrospective data using Noetik’s AI based TARIO-2 model to analyze routine H&E tumor images and identify spatial tumor microenvironment patterns linked with clinical outcomes in solid tumors, including microsatellite stable metastatic colorectal cancer, ovarian cancer, and sarcomas, with results to be presented at the 2026 ASCO Annual Meeting.
Narrative Update Jun 08

AGEN: Phase 3 Colorectal Cancer Trial Will Support Bullish Reassessment

Analyst price targets for Agenus have been reaffirmed at $15.50, with modest adjustments to the discount rate, revenue growth assumptions, profit margin and forward P/E reflecting analysts' updated view of the stock's risk profile and earnings potential. What's in the News Agenus is advancing its botensilimab plus balstilimab (BOT+BAL) program with multiple data disclosures, including new Phase 2 results in advanced cutaneous melanoma and published Phase 1b data in treatment refractory hepatocellular carcinoma.
Narrative Update May 24

AGEN: Phase 3 Colorectal Cancer Trial Will Drive Bullish Reassessment

Analysts now set a higher price target for Agenus, moving their fair value estimate from $12.33 to $15.50, citing updated assumptions around discount rates, revenue growth, profit margins, and future P/E levels. What's in the News Phase 2 data from the C-800-23 study in advanced cutaneous melanoma showed a 22% confirmed objective response rate for botensilimab plus balstilimab, with median overall survival of 16.6 months and a 42% 2 year overall survival rate in the overall cohort, and no treatment related deaths reported (Key Developments).
Narrative Update May 04

AGEN: Late Stage Cancer Data And Access Programs Will Drive Future Upside

Analysts have reduced their price targets on Agenus by $8.00 after updating their assumptions for revenue growth, profit margins, and future P/E levels to reflect a more conservative view of the stock’s valuation inputs. What's in the News Agenus is presenting four botensilimab and balstilimab abstracts at the 2026 ASCO Annual Meeting, including first Phase 2 data in advanced cutaneous melanoma and a trial-in-progress update on the Phase 3 CO.33/BATTMAN colorectal cancer study (Key Developments).
Narrative Update Apr 20

AGEN: Late Stage Gastrointestinal Cancer Data Will Drive Future Upside

Analysts have nudged their price target on Agenus higher to $8.00, reflecting updated assumptions around discount rates, revenue trends, profit margins, and future P/E expectations. What's in the News Agenus reported Phase II data from a Memorial Sloan Kettering trial combining botensilimab, balstilimab, agenT-797, ramucirumab, and paclitaxel in advanced PD-1 refractory gastroesophageal adenocarcinoma, with a 77% disease control rate in 17 patients and a subset showing survival beyond 20 months (AACR Annual Meeting 2026).
Narrative Update Apr 04

AGEN: Expanded Late-Stage Trials And Access Programs Will Drive Future Upside

Analysts have raised their price target on Agenus from $6.00 to $8.00. This reflects updated assumptions around fair value, discount rate, revenue growth, profit margin, and a higher future P/E of 28.67x compared with 19.01x previously.
Narrative Update Aug 17

Advanced Immuno-Oncology Therapies Will Reshape Future Cancer Care

The notable upward revision in Agenus’s fair value target is primarily driven by significant improvements in net profit margin and a modest increase in forecasted revenue growth, resulting in a consensus analyst price target increase from $11.00 to $12.33. What's in the News Agenus' botensilimab and balstilimab immunotherapy programs continue to show promising clinical progress, with new survival data and presentations at major oncology congresses, including a 42% two-year survival rate and 21-month median OS in immunotherapy-resistant MSS metastatic colorectal cancer.
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New Narrative Apr 08

BOT/BAL Trials And Cost Reductions Will Shape Future Advances

Strategic cost reduction and asset monetization aim to strengthen financials and fund key projects like BOT/BAL, enhancing potential revenues and earnings.
Seeking Alpha Jul 24

Agenus: Novel Drugs That Just Are Not Novel

Summary Agenus is a small biotech company focused on developing cancer treatments, with a history of poor stock performance and financial struggles. The company's primary assets in its pipeline are Botensilimab and Balstilimab, which have shown limited efficacy in pre-clinical and clinical trials. Recent FDA meeting and phase 2 metastatic colorectal cancer data plummeted AGEN stock 60%, due to discouragement to file for accelerated approval. Further funding is likely to be required soon, considering high cash burn rates and the upcoming phase 3 trial in mCRC. Read the full article on Seeking Alpha
Analysis Article May 21

There's No Escaping Agenus Inc.'s (NASDAQ:AGEN) Muted Revenues Despite A 102% Share Price Rise

Agenus Inc. ( NASDAQ:AGEN ) shareholders are no doubt pleased to see that the share price has bounced 102% in the last...
Analysis Article May 09

Analysts Have Lowered Expectations For Agenus Inc. (NASDAQ:AGEN) After Its Latest Results

Shareholders might have noticed that Agenus Inc. ( NASDAQ:AGEN ) filed its quarterly result this time last week. The...
Analysis Article Mar 29

Benign Growth For Agenus Inc. (NASDAQ:AGEN) Underpins Stock's 25% Plummet

Agenus Inc. ( NASDAQ:AGEN ) shareholders that were waiting for something to happen have been dealt a blow with a 25...

Revenue & Expenses Breakdown

How Agenus makes and spends money. Based on latest reported earnings, on an LTM basis.


Earnings and Revenue History

NasdaqCM:AGEN Revenue, expenses and earnings (USD Millions)
DateRevenueEarningsG+A ExpensesR&D Expenses
31 Mar 26124644667
31 Dec 2511405476
30 Sep 25107-3563164
30 Jun 25102-16669164
31 Mar 25100-19171164
31 Dec 24103-22772144
30 Sep 24160-228720
30 Jun 24160-224740
31 Mar 24161-240770
31 Dec 23156-24679228
30 Sep 23101-271830
30 Jun 2399-263820
31 Mar 2395-240800
31 Dec 2298-220810
30 Sep 2290-215780
30 Jun 2232018810
31 Mar 22310-19790
31 Dec 21296-24760
30 Sep 213074740
30 Jun 2169-226670
31 Mar 2185-190650
31 Dec 2088-181590
30 Sep 2091-174520
30 Jun 2097-168490
31 Mar 2085-171460
31 Dec 19150-108460
30 Sep 19122-126430
30 Jun 19115-113410
31 Mar 19115-87390
31 Dec 1837-160370
30 Sep 1839-147370
30 Jun 1829-151360
31 Mar 1818-158350
31 Dec 1743-121340
30 Sep 1740-112330
30 Jun 1741-116330
31 Mar 1744-113320
31 Dec 1623-127330
30 Sep 1625-117330
30 Jun 1627-89310
31 Mar 1627-101320
31 Dec 1525-88280
30 Sep 1519-98250

Quality Earnings: AGEN has a large one-off gain of $110.3M impacting its last 12 months of financial results to 31st March, 2026.

Growing Profit Margin: AGEN became profitable in the past.


Free Cash Flow vs Earnings Analysis


Past Earnings Growth Analysis

Earnings Trend: AGEN has become profitable over the past 5 years, growing earnings by 3.2% per year.

Accelerating Growth: AGEN has become profitable in the last year, making the earnings growth rate difficult to compare to its 5-year average.

Earnings vs Industry: AGEN has become profitable in the last year, making it difficult to compare its past year earnings growth to the Biotechs industry (54.5%).


Return on Equity

High ROE: AGEN's liabilities exceed its assets, so it is difficult to calculate its Return on Equity.


Return on Assets


Return on Capital Employed


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Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2026/07/16 21:50
End of Day Share Price 2026/07/16 00:00
Earnings2026/03/31
Annual Earnings2025/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

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Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Agenus Inc. is covered by 7 analysts. 2 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Mayank MamtaniB. Riley Securities, Inc.
Michael KingCitizens JMP Securities, LLC
Emily BodnarH.C. Wainwright & Co.