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Delcath Systems (DCTH): Evaluating Valuation After CHOPIN Phase 2 Trial Results Announcement for Uveal Melanoma

Reviewed by Kshitija Bhandaru
Delcath Systems (DCTH) has announced that results from the CHOPIN Phase 2 trial will be presented at the 2025 ESMO Congress. This puts a spotlight on its CHEMOSAT Hepatic Delivery System in metastatic uveal melanoma.
See our latest analysis for Delcath Systems.
Delcath’s recent momentum around its upcoming CHOPIN trial results has re-energized investor attention, even as the stock’s total shareholder return shines with a 1-year gain of 27%. While the latest share price has moved sideways, broader interest hints at rising confidence in Delcath’s treatment pipeline.
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So with analysts setting price targets well above current levels amid solid fundamentals, is Delcath presenting a real buying opportunity for investors, or has the market already accounted for expected future growth in the stock?
Most Popular Narrative: 54.4% Undervalued
With the consensus narrative pinning Delcath Systems' fair value at $24.33, the gap between this and the recent $11.10 closing price is impossible to ignore. This creates a situation with high-stakes financial assumptions and market-moving catalysts.
"Accelerated growth in HEPZATO and CHEMOSAT sales is being driven by increased incidence of liver and metastatic cancers due to demographic shifts, supporting long-term revenue expansion as Delcath addresses a growing clinical need. Integration into the NDRA and 340B programs increases market access, particularly among large academic centers and underserved patient populations, which is likely to drive sustained volume growth and top-line revenue, partially offsetting the per-unit pricing reduction."
Curious what is powering this outsized valuation? The story hinges on a set of aggressive growth projections and a future profit profile more typical of sector leaders. Want to know which financial levers analysts are betting on to nearly double the share price? Only the full narrative reveals the bold bets behind this bullish outlook.
Result: Fair Value of $24.33 (UNDERVALUED)
Have a read of the narrative in full and understand what's behind the forecasts.
However, delays in expanding clinical trials or intensifying competition from alternative therapies could undermine Delcath’s projected growth trajectory and valuation assumptions.
Find out about the key risks to this Delcath Systems narrative.
Build Your Own Delcath Systems Narrative
If this viewpoint does not align with your perspective or you would rather dive into the numbers firsthand, you can shape your own narrative in under three minutes: Do it your way.
A great starting point for your Delcath Systems research is our analysis highlighting 4 key rewards and 1 important warning sign that could impact your investment decision.
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This article by Simply Wall St is general in nature. We provide commentary based on historical data and analyst forecasts only using an unbiased methodology and our articles are not intended to be financial advice. It does not constitute a recommendation to buy or sell any stock, and does not take account of your objectives, or your financial situation. We aim to bring you long-term focused analysis driven by fundamental data. Note that our analysis may not factor in the latest price-sensitive company announcements or qualitative material. Simply Wall St has no position in any stocks mentioned.
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About NasdaqCM:DCTH
Delcath Systems
An interventional oncology company, focuses on the treatment of primary and metastatic liver cancers in the United States and Europe.
Flawless balance sheet and undervalued.
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