Exagen’s autoimmune testing business could grow as doctors adopt new markers for conditions like rheumatoid arthritis and lupus, but insurers are taking a harder look that may slow payments and strain near-term results. With a bigger sales footprint and a growing pharma services line, the story comes down to whether pricing and reimbursement improve fast enough to unlock the longer-term upside.Read more
Exagen is pushing to grow its autoimmune testing business by rolling out new AVISE tests, expanding its sales reach, and building more clinical proof that can persuade insurers to cover the tests more widely. The upside comes with big hurdles: the company is still losing money and faces reimbursement and technology risks that could slow adoption or squeeze what it earns per test.Read more
Catalysts About Exagen Exagen develops and commercializes advanced autoimmune diagnostic tests that improve disease detection, treatment decisions and patient monitoring. What are the underlying business or industry changes driving this perspective?Read more
Exagen Inc. designs, develops, and commercializes various testing products under the AVISE brand in the United States. The company enables healthcare providers to care for patients through the diagnosis, prognosis, and monitoring of complex rheumatic, and autoimmune and autoimmune-related diseases, including systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). The company’s lead testing product is AVISE CTD that enables differential diagnosis for patients presenting with symptoms indicative of various connective tissue diseases (CTDs) and other related diseases with overlapping symptoms. The company offers AVISE Lupus platform, a cornerstone of the SLE assessment that begins by quantifying the level of CB-CAPs biomarkers (EC4d and BC4d) in the patient’s blood; and AVISE APS that aids in the diagnosis and management of APS. In addition, it provides AVISE Vasculitis AAV, which utilizes a testing panel of individual analytes to provide physicians with results in the assessment and monitoring of anti-neutrophil cytoplasmic antibody associated vasculitis; AVISE Anti-Histone, a test for autoantibodies to histone proteins; AVISE SLE Prognostic, a panel of autoantibodies for assessing the potential for complications affecting the kidney, brain, and cardiovascular system; and AVISE Anti-CarP, a biomarker-driven RA prognostic test. Further, the company offers AVISE SLE Monitor, a blood test that employs CB-CAPs technology; AVISE MTX, a patented and validated blood test; and AVISE HCQ, a blood test to monitor levels of hydroxychloroquine. It has a research collaboration and license agreement with Allegheny Health Network (AHN) Research Institute to develop T-Cell biomarkers. The company was formerly known as Exagen Diagnostics, Inc. and changed its name to Exagen Inc. in January 2019. Exagen Inc. was incorporated in 2002 and is headquartered in Vista, California.
