Madrigal Pharmaceuticals, Inc.

NasdaqGS:MDGL Voorraadrapport

Marktkapitalisatie: US$11.8b

Madrigal Pharmaceuticals Inkomsten in het verleden

Verleden criteriumcontroles 0/6

De winst van Madrigal Pharmaceuticals is gedaald met een gemiddeld jaarlijks percentage van -9.5%, terwijl de winst van de Biotechs -industrie jaarlijks groeide met 33.8%. De inkomsten zijn groeide met een gemiddeld percentage van 90.4% per jaar.

Belangrijke informatie

-9.48%

Groei van de winst

-2.24%

Groei van de winst per aandeel

Biotechs Groei van de industrie17.04%
Inkomstengroei90.45%
Rendement op eigen vermogen-56.94%
Nettomarge-27.32%
Laatste winstupdate31 Mar 2026

Recente prestatie-updates uit het verleden

Recent updates

Narratiefupdate May 18

MDGL: MASH Pool Assumptions Versus Gross To Net Execution Will Shape Outlook

The analyst price target for Madrigal Pharmaceuticals has risen from $529 to $550. Analysts point to survey work that highlights a large MASH treatment pool and higher projected Rezdiffra use, along with updated assumptions for patient mix, revenue growth, margins, and P/E multiples.
Seeking Alpha Apr 28

Madrigal Pharmaceuticals: Boom Or Bust In MASH? Regretfully, I'm Bearish

Summary Madrigal Pharmaceuticals, Inc. receives a Sell rating, citing high valuation and intensifying MASH competition despite Rezdiffra's initial commercial success. Rezdiffra achieved $958.4m in 2025 sales with ~36,250 patients, but MDGL profitability remains elusive as operating expenses outpace revenue growth. SG&A and R&D costs are expected to rise in 2026, while no specific guidance has been provided, and consensus sees potential Q1 revenue softness. Pipeline bets and M&A speculation offer upside, but market congestion and uncertain long-term leadership prompt caution for MDGL stock after a 280% five-year gain. Read the full article on Seeking Alpha
Narratiefupdate Apr 27

MDGL: Gross To Net Execution And Margin Pressure Will Shape Balanced Outlook

Analysts have reset Madrigal Pharmaceuticals' price target to $529 from $570, reflecting updated forecasts that factor in recent commentary on gross to net adjustments, as well as revised assumptions for growth, profitability, and forward P/E. Analyst Commentary Bearish analysts have trimmed expectations for Madrigal Pharmaceuticals, pointing to updated assumptions around gross to net adjustments, as well as revisions to growth, profitability, and P/E assumptions.
Narratiefupdate Apr 13

MDGL: Gross To Net Execution And Cirrhosis Expansion Will Shape Balanced Outlook

Analyst price targets on Madrigal Pharmaceuticals have been reset to $529, with the change largely tied to updated forecasts that factor in comments on gross to net adjustments. Other recent research has introduced new bullish coverage and higher targets from different firms.
Narratiefupdate Mar 30

MDGL: MASH Combinations And Cirrhosis Expansion Will Shape Balanced Future Outlook

Analysts now set a consolidated price target for Madrigal Pharmaceuticals at $529, down from previous levels such as $570, reflecting updated forecasts around gross-to-net adjustments, even as model assumptions for revenue growth, profit margins, and future P/E remain broadly consistent. Analyst Commentary Recent research updates on Madrigal Pharmaceuticals show a mix of support and caution, with several bearish analysts rethinking how much upside is left after the stock's strong prior move and the latest company updates.
Narratiefupdate Mar 16

MDGL: Cirrhosis Expansion And MASH Combinations Will Drive Future Repricing

Analysts now set the fair value estimate for Madrigal Pharmaceuticals at $529, up $27 from $502. This reflects updated models that factor in gross to net adjustments, recent licensing activity, and mixed revisions to Street price targets across firms.
Narratiefupdate Mar 02

MDGL: MASH Franchise And DGAT2 Combo Plans Will Drive Future Upside

Madrigal Pharmaceuticals' updated analyst price target reflects a modest adjustment, with fair value edging from about $900.66 to $904.36 as analysts factor in recent target cuts around $529 to $570, alongside fresh bullish initiation and higher targets above $600 tied to updated product and combination-therapy assumptions. Analyst Commentary Recent Street research on Madrigal Pharmaceuticals shows a mix of caution and optimism, with valuation debate sitting alongside higher fair value estimates tied to execution on its MASH franchise and new pipeline additions.
Narratiefupdate Feb 16

MDGL: Future Leadership Will Rely On MASH Cirrhosis Uptake Versus GLP 1 Pressure

The analyst price target for Madrigal Pharmaceuticals has been revised higher to $671.07, up from $603.47. Analysts now factor in updated assumptions for fair value, discount rate, revenue growth, profit margins, and future P/E, following recent research that highlights both enthusiasm for Rezdiffra's commercial potential and some valuation concerns.
Narratiefupdate Feb 02

MDGL: MASH Franchise Expansion And New DGAT2 Combo Study Will Drive Upside

The updated analyst price target for Madrigal Pharmaceuticals moves from about $567 to roughly $901 per share, with analysts pointing to stronger modeled profitability, a higher assumed future P/E multiple, and continued enthusiasm for Rezdiffra across multiple research updates. Analyst Commentary Recent research coverage on Madrigal Pharmaceuticals has leaned positive overall, with a series of price target increases and a few ratings changes that highlight how divided views are at current levels.
Narratiefupdate Jan 19

MDGL: Cirrhosis Expansion And Combination Plans Will Test High Expectations

Analysts have modestly adjusted their price targets for Madrigal Pharmaceuticals, with a slight upward shift reflected in updated models that factor in Rezdiffra uptake, expanded MASH opportunities including potential combinations with ervogastat, and a range of views on valuation and longer term penetration assumptions. Analyst Commentary Recent research on Madrigal Pharmaceuticals shows a mix of optimism around Rezdiffra and its potential role in MASH, paired with increasingly careful debate around valuation, competitive pressures, and execution risks.
Narratiefupdate Jan 04

MDGL: Elevated Expectations For Cirrhosis Opportunity Will Face Heightened Competitive Pressures

Madrigal Pharmaceuticals' analyst price target has risen sharply from approximately $312 to $502 per share, as analysts factor in stronger long term profitability and higher penetration assumptions for Rezdiffra across F2-F3 and F4c MASH populations, despite moderating top line growth expectations and a modestly higher discount rate. Analyst Commentary Recent Street research reflects a broadly constructive outlook on Madrigal Pharmaceuticals, with multiple firms lifting price targets in response to stronger than expected Rezdiffra uptake and expanding commercial visibility in both F2 F3 and compensated F4c MASH populations.
Narratiefupdate Dec 20

MDGL: Future Leadership Will Depend On Cirrhosis Uptake Amid GLP 1 Competition

The analyst price target for Madrigal Pharmaceuticals has been raised by approximately $40 per share, as analysts cite stronger-than-expected real-world uptake of Rezdiffra, expanded penetration assumptions across F2, F3, and emerging F4c populations, and increased confidence in the drug's long-term commercial trajectory despite GLP-1 competition. Analyst Commentary Recent Street research reflects a strongly constructive tone on Madrigal Pharmaceuticals, with multiple firms lifting price targets into the mid to high $500s and $600s range, underpinned by faster than expected Rezdiffra adoption and expanding addressable populations across F2, F3, and emerging F4c disease.
Narratiefupdate Dec 06

MDGL: Future Leadership Will Depend On Expanding MASH Cirrhosis And Fibrosis Therapy Adoption

Madrigal Pharmaceuticals' analyst price target has been raised into the low to mid $600s per share from the high $500s, as analysts factor in stronger long term profitability expectations and sustained Rezdiffra uptake across F2-F3 and emerging F4c populations. Analyst Commentary Bullish analysts are increasingly constructive on Madrigal's outlook as they update models to reflect stronger real world Rezdiffra uptake, expanded addressable populations and emerging combination therapy optionality.
Narratiefupdate Nov 21

MDGL: Future Leadership Will Depend On Expanding Liver Fibrosis Therapy Penetration Amid Competition

Madrigal Pharmaceuticals’ analyst price target has been raised from approximately $536 to $564 per share. This reflects increased confidence among analysts in Rezdiffra’s market penetration and longer-term growth prospects, despite evolving competitive dynamics.
Analyseartikel Nov 12

Madrigal Pharmaceuticals, Inc.'s (NASDAQ:MDGL) 26% Price Boost Is Out Of Tune With Revenues

Madrigal Pharmaceuticals, Inc. ( NASDAQ:MDGL ) shares have continued their recent momentum with a 26% gain in the last...
Narratiefupdate Nov 07

MDGL: Future Revenue Leadership Will Depend On Therapy Adoption Amid Rising Competition

The analyst consensus price target for Madrigal Pharmaceuticals has increased by approximately $23 to $536, as analysts cite continued strength from Rezdiffra as well as improved long-term profitability expectations. Analyst Commentary Bullish Takeaways Bullish analysts have increased price targets for Madrigal Pharmaceuticals, emphasizing Rezdiffra’s ongoing outperformance and supportive market dynamics, even as new competitors enter the F2-F3 MASH segment.
Narratiefupdate Oct 24

EU Expansion and Combination Therapies Will Drive Future Opportunity

Analysts have increased their price target for Madrigal Pharmaceuticals by approximately $100. They now expect shares to reach around $550, citing Rezdiffra's robust launch progress, new approvals, and potential from combination therapy strategies.
Narratiefupdate Oct 10

US Patent And EU Expansion Will Secure Future Potential

The analyst price target for Madrigal Pharmaceuticals has increased by approximately $8 to $489.54. Analysts cite stronger-than-expected revenue growth, improved profit margins, and favorable momentum following recent approvals and positive market dynamics.
Narratiefupdate Sep 26

US Patent And EU Expansion Will Secure Future Potential

Analysts raised Madrigal Pharmaceuticals’ price target to $481.85, citing strong EU approval momentum, first-mover advantage for Rezdiffra in MASH, guideline inclusion, and extended patent protection driving long-term value. Analyst Commentary Bullish analysts cite Madrigal’s strong positioning to dominate the metabolic dysfunction-associated steatohepatitis (MASH) treatment landscape through its proprietary thyroid hormone receptor-beta platform.
Narratiefupdate Sep 11

US Patent And EU Expansion Will Secure Future Potential

Madrigal Pharmaceuticals’ consensus price target has been raised to $466.38 as analysts cite EU conditional approval, first-line therapy status, improved sales visibility, and extended patent protection for Rezdiffra as key drivers strengthening blockbuster potential and reducing risk. Analyst Commentary Bullish analysts believe Madrigal is uniquely positioned to dominate the metabolic dysfunction-associated steatohepatitis (MASH) market, leveraging its thyroid hormone receptor-beta platform.
Narratiefupdate Aug 27

US Patent And EU Expansion Will Secure Future Potential

The consensus analyst price target for Madrigal Pharmaceuticals was raised from $449.57 to $461.43, primarily driven by the EU approval and expanded patent protection for Rezdiffra, which de-risks future cash flows and supports robust sales expectations in a large addressable market. Analyst Commentary Bullish analysts updated their models to reflect the recent EU approval of Rezdiffra, reducing risk and subsequently lowering the discount rate applied to future cash flows.
Analyseartikel Aug 22

Madrigal Pharmaceuticals, Inc.'s (NASDAQ:MDGL) 30% Price Boost Is Out Of Tune With Revenues

Despite an already strong run, Madrigal Pharmaceuticals, Inc. ( NASDAQ:MDGL ) shares have been powering on, with a gain...
Analyseartikel Aug 13

Forecast: Analysts Think Madrigal Pharmaceuticals, Inc.'s (NASDAQ:MDGL) Business Prospects Have Improved Drastically

NasdaqGS:MDGL 1 Year Share Price vs Fair Value Explore Madrigal Pharmaceuticals's Fair Values from the Community and...
Analyseartikel Aug 08

Earnings Beat: Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) Just Beat Analyst Forecasts, And Analysts Have Been Lifting Their Forecasts

NasdaqGS:MDGL 1 Year Share Price vs Fair Value Explore Madrigal Pharmaceuticals's Fair Values from the Community and...
User avatar
Nieuw narratief May 03

FDA Approval Will Expand MASH Treatment Market Reach

First FDA-approved MASH treatment and strong U.S. market launch position Madrigal Pharmaceuticals for significant revenue growth.
Seeking Alpha Feb 26

Madrigal Pharmaceuticals Q4 Earnings Review: Strong Quarter, Even Stronger Outlook

Summary Madrigal Pharmaceuticals, Inc.'s Rezdiffra, the first approved drug for MASH, showed strong sales growth, with Q4 net sales up 66% to $103.3m. Despite a net loss of $466m in 2024, Madrigal's cash position improved to $931m, and Rezdiffra's market potential remains significant with no current competitors. Positive study data and upcoming European approval could further boost Rezdiffra's market presence, making Madrigal a prime M&A target. While GLP-1 agonists pose a potential threat, Rezdiffra's oral availability and strong initial market penetration suggest long-term growth and a solid buy opportunity for MDGL stock. Read the full article on Seeking Alpha
Seeking Alpha Jan 19

Madrigal Pharmaceuticals Rezdiffra Vies For Blockbuster Status In MASH

Summary Madrigal Pharma's REZDIFFRA achieved $100-$103M in Q4 sales, marking 61% growth, with market penetration of only 4% relative to TAM, indicating blockbuster potential. Potential competition from GLP-1 drugs and other MASH therapies exists, but REZDIFFRA's combination use and first-mover advantage mitigate these risks. Analysts project $515M in 2025 sales, driven by Medicare coverage, low market penetration, and European launch, making MDGL stock a STRONG BUY. Despite volatility and buyout speculation, Madrigal's commanding position in MASH supports a 12-month price target of $455/share. Read the full article on Seeking Alpha
Seeking Alpha Jan 09

Fast Drug Launch For Madrigal Pharmaceuticals Brings Buyout Discussion

Summary Rezdiffra's strong launch has been confirmed by robust sales in the first two quarters, even though it may have only been used in 2% of its current target patient population. Competitors with MASH therapies like NVO, SGMT, ALT and Boehringer Ingelheim are making progress, although the possibility of combinations could limit any downside for MDGL. There is ongoing discussion about a potential buyout, adding another layer of interest for investors, and a potential EU launch in H2'25. Read the full article on Seeking Alpha
Seeking Alpha Nov 03

Rezdiffra Gains Traction In NASH As Madrigal Pharmaceuticals Targets European Expansion

Summary Madrigal Pharmaceuticals' Rezdiffra has favorable initial market adoption and FDA approval, positioning it as a foundational therapy for NASH with advanced fibrosis. Broad insurance coverage and allowance for non-invasive testing [NIT] enhance patient accessibility and Rezdiffra’s adoption rate. Competition from Novo Nordisk's Semaglutide poses a market risk, but Rezdiffra’s liver-specific mechanism offers a targeted advantage. MDGL's strategic geographic expansion, particularly EMA approval in Europe, could significantly increase Rezdiffra’s TAM. Despite its cash burn, MDGL's growth and cash reserves provide enough runway. Thus, I maintain my "Buy" rating for MDGL stock. Read the full article on Seeking Alpha
Seeking Alpha Oct 24

Madrigal: Why I'm Having Doubts On The Bull Case Ahead Of Q3 Earnings

Summary Madrigal's Rezdiffra, the first FDA-approved drug for MASH, shows promise but faces competition from GLP-1 drugs and financial challenges in launching in Europe. Despite meeting Phase 3 endpoints and early sales success, Madrigal's Q3 earnings will be crucial in determining Rezdiffra's commercial viability and stock performance. The potential for Rezdiffra to achieve blockbuster status is tempered by its high cost and the emerging threat of GLP-1 agonists in the MASH market. Given the uncertainties and competitive landscape, I am downgrading Madrigal from a "Buy" to a "Hold" ahead of Q3 earnings. Read the full article on Seeking Alpha
Seeking Alpha Aug 08

While Madrigal's Rezdiffra Impresses, Great Uncertainties Loom In MASH Market

Summary Madrigal Pharmaceuticals' Q2 2024 revenue from Rezdiffra exceeded expectations at $14.6 million. The company's SG&A expenses surged to $105.4 million, reflecting launch activities. Over 2,000 patients are currently on Rezdiffra, with broad insurance coverage. I recommend selling Madrigal Pharmaceuticals due to significant uncertainties and competitive pressures. Read the full article on Seeking Alpha
Seeking Alpha Jun 09

Madrigal May Not Be Able To Shrug GLP-1 Drugs For Long

Summary Eli Lilly's tirzepatide shows potential in resolving metabolic dysfunction-associated steatohepatitis without worsening fibrosis. GLP-1 drugs pose a serious threat to Madrigal's Rezdiffra, potentially dominating the MASH market. Madrigal's financial health is stable with sufficient funding for the launch of Rezdiffra, but profitability and market prospects remain uncertain. Despite its market position, Madrigal faces substantial risks, leading to a sell recommendation. Read the full article on Seeking Alpha

Opbrengsten en kosten

Hoe Madrigal Pharmaceuticals geld verdient en uitgeeft. Gebaseerd op laatst gerapporteerde winst, op LTM-basis.


Inkomsten en omzetgeschiedenis

NasdaqGS:MDGL Opbrengsten, kosten en inkomsten (USD Millions )
DatumInkomstenInkomstenG+A UitgavenR&D-uitgaven
31 Mar 261,132-309914453
31 Dec 25958-288814389
30 Sep 25741-289715298
30 Jun 25516-282614193
31 Mar 25317-392522210
31 Dec 24180-466435237
30 Sep 2477-519340282
30 Jun 2415-510260284
31 Mar 240-444173281
31 Dec 230-374108272
30 Sep 230-34776272
30 Jun 230-33061270
31 Mar 230-31555260
31 Dec 220-29548245
30 Sep 220-27445228
30 Jun 220-25641214
31 Mar 220-24740207
31 Dec 210-24237205
30 Sep 210-23632206
30 Jun 210-23129204
31 Mar 210-21924197
31 Dec 200-20222185
30 Sep 200-17121156
30 Jun 200-13420122
31 Mar 200-1052293
31 Dec 190-842372
30 Sep 190-682356
30 Jun 190-552443
31 Mar 190-421933
31 Dec 180-331525
30 Sep 180-301223
30 Jun 180-30924
31 Mar 180-32825
31 Dec 170-31824
30 Sep 170-30723
30 Jun 170-36925
31 Mar 170-31820
31 Dec 160-26716
30 Sep 160-21511
30 Jun 160-814
31 Mar 160-713

Kwaliteitswinsten: MDGL is momenteel verliesgevend.

Groeiende winstmarge: MDGL is momenteel verliesgevend.


Analyse vrije kasstroom versus winst


Analyse van de winstgroei in het verleden

Winsttrend: MDGL is verliesgevend en de verliezen zijn de afgelopen 5 jaar toegenomen met een snelheid van 9.5% per jaar.

Versnelling van de groei: Het is niet mogelijk om de winstgroei van MDGL over het afgelopen jaar te vergelijken met het gemiddelde over de afgelopen vijf jaar, omdat het bedrijf momenteel verliesgevend is.

Winst versus industrie: MDGL is verlieslatend, waardoor het lastig is om de winstgroei van het afgelopen jaar te vergelijken met die van de Biotechs industrie ( 43% ).


Rendement op eigen vermogen

Hoge ROE: MDGL heeft een negatief Return on Equity ( -56.94% ), omdat het momenteel verliesgevend is.


Rendement op activa


Rendement op geïnvesteerd vermogen


Ontdek sterk presterende bedrijven uit het verleden

Bedrijfsanalyse en status van financiële gegevens

GegevensLaatst bijgewerkt (UTC-tijd)
Bedrijfsanalyse2026/05/22 06:10
Aandelenkoers aan het einde van de dag2026/05/22 00:00
Inkomsten2026/03/31
Jaarlijkse inkomsten2025/12/31

Gegevensbronnen

De gegevens die gebruikt zijn in onze bedrijfsanalyse zijn afkomstig van S&P Global Market Intelligence LLC. De volgende gegevens worden gebruikt in ons analysemodel om dit rapport te genereren. De gegevens zijn genormaliseerd, waardoor er een vertraging kan optreden voordat de bron beschikbaar is.

PakketGegevensTijdframeVoorbeeld Amerikaanse bron *
Financiële gegevens bedrijf10 jaar
  • Resultatenrekening
  • Kasstroomoverzicht
  • Balans
Consensus schattingen analisten+3 jaar
  • Financiële prognoses
  • Koersdoelen analisten
Marktprijzen30 jaar
  • Aandelenprijzen
  • Dividenden, splitsingen en acties
Eigendom10 jaar
  • Top aandeelhouders
  • Handel met voorkennis
Beheer10 jaar
  • Leiderschapsteam
  • Raad van bestuur
Belangrijkste ontwikkelingen10 jaar
  • Bedrijfsaankondigingen

* Voorbeeld voor effecten uit de VS, voor niet-Amerikaanse effecten worden gelijkwaardige formulieren en bronnen gebruikt.

Tenzij anders vermeld zijn alle financiële gegevens gebaseerd op een jaarperiode, maar worden ze elk kwartaal bijgewerkt. Dit staat bekend als Trailing Twelve Month (TTM) of Last Twelve Month (LTM) gegevens. Meer informatie.

Analysemodel en Snowflake

Details van het analysemodel dat is gebruikt om dit rapport te genereren zijn beschikbaar op onze Github-pagina. We hebben ook handleidingen over hoe je onze rapporten kunt gebruiken en tutorials op YouTube.

Leer meer over het team van wereldklasse dat het Simply Wall St-analysemodel heeft ontworpen en gebouwd.

Industrie en sector

Onze industrie- en sectormetrics worden elke 6 uur berekend door Simply Wall St, details van ons proces zijn beschikbaar op Github.

Bronnen van analisten

Madrigal Pharmaceuticals, Inc. wordt gevolgd door 28 analisten. 15 van deze analisten hebben de schattingen van de omzet of winst ingediend die zijn gebruikt als input voor ons rapport. Inzendingen van analisten worden de hele dag door bijgewerkt.

AnalistInstelling
Eliana MerleBarclays
Matthew LuchiniBMO Capital Markets Equity Research
Jason ZemanskyBofA Global Research