View Future GrowthCodexis 과거 순이익 실적과거 기준 점검 0/6Codexis 의 수입은 연평균 -19.7%의 비율로 감소해 온 반면, Life Sciences 산업은 연평균 3.8%의 비율로 감소했습니다. 매출은 연평균 13.3%의 비율로 감소해 왔습니다.핵심 정보-19.74%순이익 성장률-14.71%주당순이익(EPS) 성장률Life Sciences 산업 성장률21.51%매출 성장률-13.25%자기자본이익률-73.99%순이익률-40.96%최근 순이익 업데이트31 Mar 2026최근 과거 실적 업데이트Reported Earnings • May 11First quarter 2026 earnings: EPS and revenues exceed analyst expectationsFirst quarter 2026 results: US$0.096 loss per share (improved from US$0.25 loss in 1Q 2025). Revenue: US$15.2m (up 102% from 1Q 2025). Net loss: US$8.70m (loss narrowed 58% from 1Q 2025). Revenue exceeded analyst estimates by 5.0%. Earnings per share (EPS) also surpassed analyst estimates by 27%. Revenue is forecast to grow 20% p.a. on average during the next 3 years, compared to a 6.5% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has increased by 18% per year but the company’s share price has only increased by 1% per year, which means it is significantly lagging earnings growth.공시 • Apr 23Codexis, Inc. to Report Q1, 2026 Results on May 07, 2026Codexis, Inc. announced that they will report Q1, 2026 results After-Market on May 07, 2026Reported Earnings • Mar 12Full year 2025 earnings: EPS and revenues exceed analyst expectationsFull year 2025 results: US$0.51 loss per share (improved from US$0.89 loss in FY 2024). Revenue: US$70.4m (up 19% from FY 2024). Net loss: US$44.0m (loss narrowed 33% from FY 2024). Revenue exceeded analyst estimates by 4.6%. Earnings per share (EPS) also surpassed analyst estimates by 22%. Revenue is forecast to grow 22% p.a. on average during the next 3 years, compared to a 6.3% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has increased by 4% per year but the company’s share price has fallen by 25% per year, which means it is significantly lagging earnings.공시 • Feb 25Codexis, Inc. to Report Q4, 2025 Results on Mar 11, 2026Codexis, Inc. announced that they will report Q4, 2025 results After-Market on Mar 11, 2026공시 • Oct 23Codexis, Inc. to Report Q3, 2025 Results on Nov 06, 2025Codexis, Inc. announced that they will report Q3, 2025 results After-Market on Nov 06, 2025Reported Earnings • Aug 14Second quarter 2025 earnings: EPS and revenues exceed analyst expectationsSecond quarter 2025 results: US$0.15 loss per share (improved from US$0.32 loss in 2Q 2024). Revenue: US$15.3m (up 92% from 2Q 2024). Net loss: US$13.3m (loss narrowed 42% from 2Q 2024). Revenue exceeded analyst estimates by 8.1%. Earnings per share (EPS) also surpassed analyst estimates by 15%. Revenue is forecast to grow 24% p.a. on average during the next 3 years, compared to a 6.0% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 20% per year but the company’s share price has fallen by 28% per year, which means it is performing significantly worse than earnings.모든 업데이트 보기Recent updatesPrice Target Changed • May 11Price target decreased by 7.1% to US$6.58Down from US$7.08, the current price target is an average from 6 analysts. New target price is 148% above last closing price of US$2.65. Stock is up 0.4% over the past year. The company is forecast to post a net loss per share of US$0.40 next year compared to a net loss per share of US$0.50 last year.분석 기사 • May 11US$6.58: That's What Analysts Think Codexis, Inc. (NASDAQ:CDXS) Is Worth After Its Latest ResultsA week ago, Codexis, Inc. ( NASDAQ:CDXS ) came out with a strong set of quarterly numbers that could potentially lead...Reported Earnings • May 11First quarter 2026 earnings: EPS and revenues exceed analyst expectationsFirst quarter 2026 results: US$0.096 loss per share (improved from US$0.25 loss in 1Q 2025). Revenue: US$15.2m (up 102% from 1Q 2025). Net loss: US$8.70m (loss narrowed 58% from 1Q 2025). Revenue exceeded analyst estimates by 5.0%. Earnings per share (EPS) also surpassed analyst estimates by 27%. Revenue is forecast to grow 20% p.a. on average during the next 3 years, compared to a 6.5% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has increased by 18% per year but the company’s share price has only increased by 1% per year, which means it is significantly lagging earnings growth.공시 • Apr 30Codexis, Inc., Annual General Meeting, Jun 17, 2026Codexis, Inc., Annual General Meeting, Jun 17, 2026.Breakeven Date Change • Apr 26No longer forecast to breakevenThe 7 analysts covering Codexis no longer expect the company to break even during the foreseeable future. The company was expected to make a profit of US$20.0m in 2028. New consensus forecast suggests the company will make a loss of US$1.11m in 2028.공시 • Apr 23Codexis, Inc. to Report Q1, 2026 Results on May 07, 2026Codexis, Inc. announced that they will report Q1, 2026 results After-Market on May 07, 2026Reported Earnings • Mar 12Full year 2025 earnings: EPS and revenues exceed analyst expectationsFull year 2025 results: US$0.51 loss per share (improved from US$0.89 loss in FY 2024). Revenue: US$70.4m (up 19% from FY 2024). Net loss: US$44.0m (loss narrowed 33% from FY 2024). Revenue exceeded analyst estimates by 4.6%. Earnings per share (EPS) also surpassed analyst estimates by 22%. Revenue is forecast to grow 22% p.a. on average during the next 3 years, compared to a 6.3% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has increased by 4% per year but the company’s share price has fallen by 25% per year, which means it is significantly lagging earnings.공시 • Mar 12Codexis, Inc. Provides Earnings Guidance for Full Year 2026Codexis, Inc. provided earnings guidance for full year 2026. The company expects total revenues are expected to be in the range of $72 million to $76 million.공시 • Feb 25Codexis, Inc. to Report Q4, 2025 Results on Mar 11, 2026Codexis, Inc. announced that they will report Q4, 2025 results After-Market on Mar 11, 2026New Risk • Feb 24New minor risk - Market cap sizeThe company's market capitalization is less than US$100m. Market cap: US$96.6m This is considered a minor risk. Companies with a small market capitalization are most likely businesses that have not yet released a product to market or are simply a very small company without a wide reach. Either way, risk is elevated with these companies because there is a chance the product may not come to fruition or the company's addressable market or demand may not be as large as expected. In addition, if the company's size is the main factor, it is less likely to have many investors and analysts following it and scrutinizing its performance and outlook. Currently, the following risks have been identified for the company: Minor Risks Less than 1 year of cash runway based on current free cash flow (-US$62m). Market cap is less than US$100m (US$96.6m market cap).분석 기사 • Feb 12Positive Sentiment Still Eludes Codexis, Inc. (NASDAQ:CDXS) Following 29% Share Price SlumpCodexis, Inc. ( NASDAQ:CDXS ) shareholders that were waiting for something to happen have been dealt a blow with a 29...Breakeven Date Change • Feb 06Forecast to breakeven in 2028The 6 analysts covering Codexis expect the company to break even for the first time. New consensus forecast suggests the company will make a profit of US$20.0m in 2028. Average annual earnings growth of 61% is required to achieve expected profit on schedule.Board Change • Feb 06High number of new directorsThere are 6 new directors who have joined the board in the last 3 years. President, CEO & Director Alison Moore was the last director to join the board, commencing their role in 2025. The company’s lack of board continuity is considered a risk according to the Simply Wall St Risk Model.공시 • Nov 07+ 2 more updatesCodexis, Inc. Announces Workforce ReductionIn November 2025, Codexis eliminated 46 positions, or approximately 24% of its workforce. The company expects to recognize an additional expense of approximately $3.5 million in the fourth quarter of 2025.공시 • Oct 23Codexis, Inc. to Report Q3, 2025 Results on Nov 06, 2025Codexis, Inc. announced that they will report Q3, 2025 results After-Market on Nov 06, 2025Seeking Alpha • Sep 16Codexis Weighs ECO Scale As Cash Runway TightensSummary Codexis is considering shifting from enzyme supply to ECO Synthesis. This way, they could target siRNA as a near-term commercial wedge with engineered ligases. ECO could convert lab projects into GLP, then GMP supply. So far, 3 CDMOs have already replicated Codexis’s ligation processes, which bodes well for CDXS. However, in the near term, management may prioritize scaling up ECO over reaching breakeven. This is a risk, given their cash runway is somewhat tight already. After all, CDXS’s liquidity could become strained with potential added CAPEX for capacity and staffing if they pursue ECO growth. Overall, I think their valuation is reasonable at this stage, but the cash burn risks nudge me towards a neutral rating on CDXS until we see further growth. Read the full article on Seeking AlphaReported Earnings • Aug 14Second quarter 2025 earnings: EPS and revenues exceed analyst expectationsSecond quarter 2025 results: US$0.15 loss per share (improved from US$0.32 loss in 2Q 2024). Revenue: US$15.3m (up 92% from 2Q 2024). Net loss: US$13.3m (loss narrowed 42% from 2Q 2024). Revenue exceeded analyst estimates by 8.1%. Earnings per share (EPS) also surpassed analyst estimates by 15%. Revenue is forecast to grow 24% p.a. on average during the next 3 years, compared to a 6.0% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 20% per year but the company’s share price has fallen by 28% per year, which means it is performing significantly worse than earnings.공시 • Jul 31Codexis, Inc. to Report Q2, 2025 Results on Aug 13, 2025Codexis, Inc. announced that they will report Q2, 2025 results After-Market on Aug 13, 2025분석 기사 • Jul 03What You Can Learn From Codexis, Inc.'s (NASDAQ:CDXS) P/SWhen you see that almost half of the companies in the Life Sciences industry in the United States have price-to-sales...공시 • May 22Codexis, Inc. Presents Data at the Tides USA Annual Meeting in San Diego, CaliforniaCodexis, Inc. presented data at the TIDES USA annual meeting in San Diego, California. Codexis' presentations showcased its proprietary ECO Synthesis platform's ability to support siRNA manufacturing by reducing purification costs, improving process performance, and demonstrating the potential to control stereochemistry. During an oral Main Stage presentation, Codexis used inclisiran as an example to showcase how the use of mobilized enzymes in its ECO Synthesis platform delivers a consistent process with improved performance. Using sequential enzymatic synthesis, company: Continued to achieve consistent coupling efficiency of >98% Maintained the delivery of high product quality; Successfully decreased average cycle time by approximately 24%, translating into reduced production time; Demonstrated high yields of 30 grams of siRNA per liter. Using Codexis' ligase to manufacture siRNA, company data demonstrated the potential to reduce or eliminate costly downstream purification steps. This benefit of ligation has led many companies to explore using this method in siRNA manufacturing. The company's poster presentation highlighted how the Company's recently launched machine learning tool is improving the success rate of ligation to produce siRNA. The tool aids process design by guiding the selection of optimal pairings of ligases and RNA fragments and has been shown to significantly outperform traditional fragment selection by four to sixfold. By accelerating the ligase selection process and maximizing ligation efficiency, this tool demonstrates the potential to reduce process development time, lower costs, and enable an efficient manufacturing process for customers. Three CDMO Collaborator Presentations feature the Use of Codexis Ligases to Combine Short RNA Fragments: In addition to Codexis' presentations, Bachem, Nitto Avecia, and ST Pharm, three leading CDMOs in siRNA manufacturing, presented data on the use of Codexis ligases to successfully combine short RNA fragments. In a separate TIDES Talk presentation, Codexis highlighted a new feature under development for the ECO Synthesis technology to allow for stereochemical control during oligonucleotide synthesis. In contrast, the data in this oral presentation demonstrate how the ECO Synthesis platform can enable control over stereochemistry under process-relevant conditions.분석 기사 • May 17Codexis, Inc. (NASDAQ:CDXS) Just Released Its First-Quarter Results And Analysts Are Updating Their EstimatesCodexis, Inc. ( NASDAQ:CDXS ) missed earnings with its latest first-quarter results, disappointing overly-optimistic...New Risk • May 15New major risk - Financial positionThe company has less than a year of cash runway based on its current free cash flow trend. Free cash flow: -US$60m This is considered a major risk. With less than a year's worth of cash, the company will need to raise capital or take on debt unless its cash flows improve. This would dilute existing shareholders or increase balance sheet risk. Currently, the following risks have been identified for the company: Major Risk Less than 1 year of cash runway based on free cash flow trend (-US$60m free cash flow). Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$9.9m net loss in 3 years). Share price has been volatile over the past 3 months (14% average weekly change). Shareholders have been diluted in the past year (17% increase in shares outstanding).Reported Earnings • May 15First quarter 2025 earnings: EPS and revenues miss analyst expectationsFirst quarter 2025 results: US$0.25 loss per share (further deteriorated from US$0.17 loss in 1Q 2024). Revenue: US$7.54m (down 56% from 1Q 2024). Net loss: US$20.7m (loss widened 80% from 1Q 2024). Revenue missed analyst estimates by 22%. Earnings per share (EPS) also missed analyst estimates by 5.4%. Revenue is forecast to grow 24% p.a. on average during the next 3 years, compared to a 6.0% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 30% per year but the company’s share price has fallen by 38% per year, which means it is performing significantly worse than earnings.공시 • May 15Codexis, Inc. Reiterates Earnings Guidance for Full-Year 2025Codexis, Inc. Reiterated earnings guidance for full-year 2025. The company expects total revenues to be in the range of $64 million to $68 million.공시 • May 01Codexis, Inc. to Report Q1, 2025 Results on May 14, 2025Codexis, Inc. announced that they will report Q1, 2025 results After-Market on May 14, 2025공시 • Apr 28Codexis, Inc., Annual General Meeting, Jun 10, 2025Codexis, Inc., Annual General Meeting, Jun 10, 2025.공시 • Apr 10Codexis, Inc. Announces Retirement of Byron L. Dorgan as DirectorOn April 4, 2025, Byron L. Dorgan provided notice to the board of directors of Codexis, Inc. of his intention to retire and not to stand for reelection to the Board at the expiration of his current term at the Company’s 2025 Annual Meeting of Stockholders (the “2025 Annual Meeting”). Mr. Dorgan’s decision not to stand for reelection is not the result of any disagreement with the Company on any matter relating to its operations, policies, practices or otherwise. Mr. Dorgan will remain a director until the 2025 Annual Meeting. Mr. Dorgan joined the Board in 2011, served as Chairman from 2021 through 2024, and currently serves as the Chair of the Nominating and Corporate Governance Committee. He will remain a consultant to Codexis for one year following his departure from the Board.공시 • Apr 01Codexis, Inc. Appoints Cynthia Collins to the Board of DirectorsCodexis, Inc. announced the appointment of Cynthia Collins to the company’s board of directors. Cynthia Collins is a recognized leader with more than four decades of experience working in the pharmaceutical and biotech industry. She currently serves as Executive Chair and interim CEO of Nutcracker Therapeutics, a contract, research, development and manufacturing organization with a next generation RNA precision manufacturing platform. Previously, she was the CEO of Editas Medicine, a premier CRISPR company where she oversaw the first clinical trial administration of an in vivo CRISPR gene editing therapy. Her other notable roles include CEO of Human Longevity, CEO and general manager of various life science businesses at GE Healthcare, CEO of GenVec, group vice president at Beckman Coulter, CEO of Sequoia Pharmaceuticals, and president of oncology at Baxter Healthcare. Ms. Collins also currently serves as a board member at Certara, MaxCyte, DermTech, Alanis Therapeutics, Draper Laboratories, and Foundation for mRNA Medicines. She holds a bachelor’s degree in microbiology from the University of Illinois Urbana-Champaign and an MBA from the University of Chicago Booth School of Business.새로운 내러티브 • Mar 29ECO Synthesis Launch In 2025 Will Unlock Pharma Contracts Transitioning to commercial execution with ECO Synthesis and partnerships enhances revenue growth by securing new contracts and expanding into pharma and biotech segments. 분석 기사 • Mar 28Codexis, Inc. (NASDAQ:CDXS) Stocks Pounded By 27% But Not Lagging Industry On Growth Or PricingUnfortunately for some shareholders, the Codexis, Inc. ( NASDAQ:CDXS ) share price has dived 27% in the last thirty...Breakeven Date Change • Mar 07Forecast to breakeven in 2027The 7 analysts covering Codexis expect the company to break even for the first time. New consensus forecast suggests losses will reduce by 25% per year to 2026. The company is expected to make a profit of US$5.11m in 2027. Average annual earnings growth of 56% is required to achieve expected profit on schedule.New Risk • Mar 03New minor risk - ProfitabilityThe company is currently unprofitable and not forecast to become profitable over the next 3 years. Trailing 12-month net loss: US$65m Forecast net loss in 3 years: US$6.6m This is considered a minor risk. Companies that are not profitable are more likely to be burning through cash and less likely to be well established. Ultimately, shareholders want to see a good return on their investment and that generally comes from sharing in the company's profits. Without profits, the company is under pressure to grow significantly while potentially having to reduce costs and possibly needing to take on debt or raise capital to remain afloat. Currently, the following risks have been identified for the company: Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$6.6m net loss in 3 years). Share price has been volatile over the past 3 months (11% average weekly change). Shareholders have been diluted in the past year (18% increase in shares outstanding).New Risk • Mar 01New minor risk - Share price stabilityThe company's share price has been volatile over the past 3 months. It is more volatile than 75% of American stocks, typically moving 9.2% a week. This is considered a minor risk. Share price volatility indicates the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. It also increases the risk of potential losses in the short term as the stock tends to have larger drops in price more frequently than other stocks. Currently, the following risks have been identified for the company: Minor Risks Share price has been volatile over the past 3 months (9.2% average weekly change). Shareholders have been diluted in the past year (16% increase in shares outstanding).Breakeven Date Change • Feb 28Forecast to breakeven in 2027The 7 analysts covering Codexis expect the company to break even for the first time. New consensus forecast suggests losses will reduce by 23% per year to 2026. The company is expected to make a profit of US$5.11m in 2027. Average annual earnings growth of 58% is required to achieve expected profit on schedule.공시 • Feb 28Codexis, Inc. Provides Earnings Guidance for 2025Codexis, Inc. provided earnings guidance for 2025. The company expects total revenues to be in the range of $64 million to $68 million.공시 • Feb 14Codexis, Inc. to Report Q4, 2024 Results on Feb 27, 2025Codexis, Inc. announced that they will report Q4, 2024 results at 4:00 PM, US Eastern Standard Time on Feb 27, 2025공시 • Feb 09Codexis, Inc. Appoints Arthur Levin to Strategic Advisory BoardCodexis, Inc. announced the appointment of Arthur Levin, PhD, to the Company’s Strategic Advisory Board (SAB). Dr. Levin is a founding member of Avidity Biosciences, and currently serves on its Board of Directors. He brings three decades of experience developing oligonucleotides to Codexis as it continues to onboard customers for its Enzyme Catalyzed Oligonucleotide (ECO) Synthesis™ manufacturing platform. In addition to his role on the Board of Directors, Dr. Levin previously held the positions of Distinguished Scientist, Strategic Leader and Chief Scientific Officer at Avidity. Dr. Levin is a highly regarded key opinion leader in the RNA therapeutics field who has led teams responsible for the development of many oligonucleotides. Prior to joining Avidity, Dr. Levin was the Executive Vice President of Research and Development at miRagen Therapeutics and held senior drug development roles at Ionis (formerly Isis) Pharmaceuticals and Santaris Pharmaceuticals. He has published more than 100 scientific articles and has authored several of the most cited reviews in the field. In addition to Codexis, he serves on the scientific advisory boards of multiple institutions. Dr. Levin received a doctorate in toxicology from the University of Rochester and holds a bachelor’s degree in biology from Muhlenberg College.Buy Or Sell Opportunity • Jan 27Now 22% undervaluedOver the last 90 days, the stock has risen 48% to US$4.72. The fair value is estimated to be US$6.09, however this is not to be taken as a buy recommendation but rather should be used as a guide only. Revenue has declined by 22% over the last 3 years. Earnings per share has declined by 46%. For the next 3 years, revenue is forecast to grow by 21% per annum. Earnings are also forecast to grow by 48% per annum over the same time period.공시 • Jan 17Codexis, Inc. Appoints Christos Richards to Board of DirectorsCodexis, Inc. announced the appointment of Christos Richards to the Company’s Board of Directors. Christos Richards brings over 30 years of global executive advisory and search experience for the biopharmaceutical and healthcare industry to Codexis. To date, he has completed more than 450 executive level assignments, including over 200 Board, CEO and CEO succession projects in the Life Sciences sector. He currently serves as Global Head of Healthcare and Life Sciences at Calibre One, a global executive search firm with offices across California as well as Chicago, New York and London. Mr. Richards serves clients from venture-backed startups to leading global enterprises in devices, diagnostics, agricultural biotechnology, animal health, tools, services and digital health sectors. He has spent 20 years as a partner with two prominent boutique search firms, including serving as Chief Executive Officer of Levin & Company. Mr. Richards previously served on the Board of Directors for Coherus BioSciences and is also an advisor for the University of California, San Francisco Innovation Ventures Entrepreneurship Center. He holds a diploma in hospitality management from Schweizerische Wirteschule in Lucerne/Davos, Switzerland.Buy Or Sell Opportunity • Jan 08Now 22% undervaluedOver the last 90 days, the stock has risen 60% to US$4.76. The fair value is estimated to be US$6.09, however this is not to be taken as a buy recommendation but rather should be used as a guide only. Revenue has declined by 22% over the last 3 years. Earnings per share has declined by 46%. For the next 3 years, revenue is forecast to grow by 21% per annum. Earnings are also forecast to grow by 48% per annum over the same time period.분석 기사 • Jan 06Estimating The Intrinsic Value Of Codexis, Inc. (NASDAQ:CDXS)Key Insights Using the 2 Stage Free Cash Flow to Equity, Codexis fair value estimate is US$6.13 With US$5.43 share...분석 기사 • Dec 10Is Codexis (NASDAQ:CDXS) Using Debt In A Risky Way?Some say volatility, rather than debt, is the best way to think about risk as an investor, but Warren Buffett famously...공시 • Nov 15Codexis, Inc. Unveils Pioneering Enzymatic Synthesis Data to Enable the Future Manufacturing of RNAi TherapeuticsCodexis, Inc. announced data from three presentations at the TIDES Europe annual meeting being held November 12-14, 2024, in Hamburg, Germany. The data demonstrate the Company’s rapid advancement of its Enzyme Catalyzed Oligonucleotide (ECO) Synthesis™ manufacturing platform and establish Codexis’ position at the forefront of enzymatic synthesis technology to enable to ongoing expansion of RNAi therapeutics. During an oral Spotlight Presentation, Codexis unveiled the successful end-to-end enzymatic synthesis of an entire approved siRNA therapeutic asset, inclisiran. Codexis enzymatically synthesized the full-length sense and antisense strands of the molecule, including the enzymatic incorporation of a tissue-targeting moiety to the sense strand. To date, this process has only been completed utilizing phosphoramidite chemistry, a process that involves the use of harsh chemical conditions and vast amounts of toxic organic solvents. By contrast, Codexis’ ECO Synthesis manufacturing platform operates under milder, aqueous conditions, that improves product quality and dramatically decreases chemical waste production. In addition to this fully enzymatic route of synthesis, the Company demonstrated similar outcomes utilizing three routes of enzymatic ligation to produce the siRNA therapeutic asset, combining oligonucleotide fragments made by sequential enzymatic synthesis and traditional phosphoramidite chemistry. Key data from the presentation include: Achieved incorporation efficiency of >98% during sequential enzymatic oligo synthesis. Successfully attached the tri-GalNAc tissue-targeting moiety by enzymatic ligation. Obtained full-length oligonucleotides of equal quality and yields, using ligation of short fragments made with enzymes or by traditional phosphoramidite chemistry. Now that Codexis has successfully achieved this unprecedented milestone, the Company will continue to optimize its process for robustness, scaled-up quantities and improved purity with the goal of providing customers with siRNA material of comparable or better quality to phosphoramidite chemistry. The Company anticipates ramping up manufacturing of siRNA in quantities for preclinical testing following the successful build out of its ECO Synthesis Innovation Lab at the end of this year. Two additional presentations focused on results of direct comparisons of Codexis’ engineered double-stranded RNA (dsRNA) ligases and wild-type (WT) enzymes when used to combine short oligonucleotide fragments to synthesize full-length siRNA therapeutic compounds. In a joint poster with Bachem, one of the world’s leading CDMOs in oligonucleotide manufacturing, the data provided compelling external validation of the superior performance of Codexis ligases over existing wild-type enzymes in use today. Codexis enzymes demonstrated superior performance over wild-type enzymes across both volumetric productivity and substrate versatility. These dsRNA ligases outperformed on multiple substrate designs and enabled a higher conversion rate of oligonucleotide fragments into siRNA at increased concentrations of raw materials. In a separate TIDES Talk presentation, Codexis demonstrated improved performance of its dsRNA ligase over WT enzymes based on real customer case studies executed through the Company’s RNA Ligase Screening and Optimization Services, launched in May 2024. Codexis’ engineered ligases delivered robust, in-process performance, including higher substrate loading, faster reaction times and improved conversation at elevated temperatures. These data demonstrate the Company’s ability to accelerate delivery of lead ligase variants to customers and optimize process conditions for a customer’s specific asset.공시 • Nov 13Codexis, Inc. Appoints Raymond De Vré to Board of DirectorsCodexis, Inc. announced the appointment of Raymond De Vré, PhD, to the Company’s Board of Directors. Dr. De Vré brings over 20 years of executive-level experience to Codexis. He currently serves as Managing Director at RADV Advisory, an independent strategic and operational advisory company focused on investments in the global healthcare and contract development and manufacturing organization (CDMO) space. Prior to founding RADV Advisory, he was the Chief Executive Officer of PolyPeptide Group, a CDMO focused on peptide- and oligonucleotide-based therapies for pharmaceutical and biotech companies globally. Prior to PolyPeptide, Dr. De Vré held multiple senior leadership roles at Dr. Reddy’s Laboratories, including Senior Vice President, Head of Biologics, and served as a member of the Management Council. Earlier in his career, he was a Partner at McKinsey & Company, working mostly in the pharmaceutical and biotech practice. Dr. De Vré holds a PhD in Applied Physics from Stanford University and a master’s degree in engineering from Université Libre de Bruxelles.분석 기사 • Nov 07Codexis, Inc.'s (NASDAQ:CDXS) 29% Jump Shows Its Popularity With InvestorsCodexis, Inc. ( NASDAQ:CDXS ) shareholders have had their patience rewarded with a 29% share price jump in the last...New Risk • Nov 04New minor risk - Shareholder dilutionThe company's shareholders have been diluted in the past year. Increase in shares outstanding: 17% This is considered a minor risk. Shareholder dilution occurs when there is an increase in the number of shares on issue that is not proportionally distributed between all shareholders. Often due to the company raising equity capital or some options being converted into stock. All else being equal, if there are more shares outstanding then each existing share will be entitled to a lower proportion of the company's total earnings, thus reducing earnings per share (EPS). While dilution might not always result in lower EPS (like if the company is using the capital to fund an EPS accretive acquisition) in a lot cases it does, along with lower dividends per share and less voting power at shareholder meetings. Currently, the following risks have been identified for the company: Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$18m net loss in 3 years). Shareholders have been diluted in the past year (17% increase in shares outstanding).Reported Earnings • Nov 01Third quarter 2024 earnings: Revenues exceed analysts expectations while EPS lags behindThird quarter 2024 results: US$0.29 loss per share (improved from US$0.50 loss in 3Q 2023). Revenue: US$12.8m (up 38% from 3Q 2023). Net loss: US$20.6m (loss narrowed 41% from 3Q 2023). Revenue exceeded analyst estimates by 12%. Earnings per share (EPS) missed analyst estimates by 21%. Revenue is forecast to grow 20% p.a. on average during the next 3 years, compared to a 6.5% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 46% per year but the company’s share price has fallen by 56% per year, which means it is performing significantly worse than earnings.공시 • Oct 11Codexis, Inc. to Report Q3, 2024 Results on Oct 31, 2024Codexis, Inc. announced that they will report Q3, 2024 results After-Market on Oct 31, 2024공시 • Oct 03Codexis, Inc. Announces Executive ChangesCodexis, Inc. announced an increase in its cash reserves through capital raises totaling $31 million via the Company’s existing at-the-market facility during the quarter ended September 30, 2024. In addition to the financing, the Company strengthened its management team through the appointments of Alison Moore, PhD, to the newly created role of Chief Technology Officer. The Company also announced the appointment of John Schiffhauer as Senior Vice President of Intellectual Property. Mr. Schiffhauer brings over 20 years of experience in legal operations and intellectual property at Intel, and most recently, Zymergen, to this newly created role focused on managing the Company’s complex IP portfolio and executing strategic partnerships around it. Alison Moore brings to Codexis significant experience as a biotechnology and pharmaceutical executive, including an extensive background in biomanufacturing. She is former Chief Technical Officer of Allogene Therapeutics, a pioneering clinical-stage company advancing CAR-T therapies. Prior to Allogene, she spent a total of 20 years at Amgen, most recently as Senior Vice President, Process Development, and including roles in Supply Chain and Manufacturing. Dr. Moore also has experience at Genentech as a Director in Chemistry, Manufacturing and Controls, and in Regulatory Affairs. Dr. Moore holds a bachelor’s degree in pharmacology with honors and a doctorate degree in cell biology from Manchester University, England.Major Estimate Revision • Aug 19Consensus EPS estimates fall by 12%The consensus outlook for fiscal year 2024 has been updated. 2024 expected loss increased from -US$0.676 to -US$0.755 per share. Revenue forecast unchanged at US$65.1m. Life Sciences industry in the US expected to see average net income growth of 20% next year. Consensus price target of US$7.17 unchanged from last update. Share price rose 6.7% to US$3.01 over the past week.Major Estimate Revision • Aug 15Consensus EPS estimates fall by 11%The consensus outlook for fiscal year 2024 has been updated. 2024 expected loss increased from -US$0.676 to -US$0.75 per share. Revenue forecast unchanged at US$65.2m. Life Sciences industry in the US expected to see average net income growth of 20% next year. Consensus price target of US$7.43 unchanged from last update. Share price fell 11% to US$2.81 over the past week.Reported Earnings • Aug 09Second quarter 2024 earnings: Revenues exceed analysts expectations while EPS lags behindSecond quarter 2024 results: US$0.32 loss per share (further deteriorated from US$0.17 loss in 2Q 2023). Revenue: US$7.98m (down 63% from 2Q 2023). Net loss: US$22.8m (loss widened 98% from 2Q 2023). Revenue exceeded analyst estimates by 2.0%. Earnings per share (EPS) missed analyst estimates by 21%. Revenue is forecast to grow 19% p.a. on average during the next 3 years, compared to a 6.7% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 51% per year and the company’s share price has also fallen by 51% per year.공시 • Aug 09Codexis, Inc. Reiterates Earnings Guidance for the Full Year 2024Codexis, Inc. reiterated earnings guidance for the full year 2024. For the year, Product revenues are expected to be in the range of $38 million to $42 million, excluding revenue related to PAXLOVID.분석 기사 • Jul 26After Leaping 26% Codexis, Inc. (NASDAQ:CDXS) Shares Are Not Flying Under The RadarCodexis, Inc. ( NASDAQ:CDXS ) shares have continued their recent momentum with a 26% gain in the last month alone...공시 • Jul 19Codexis, Inc. to Report Q2, 2024 Results on Aug 08, 2024Codexis, Inc. announced that they will report Q2, 2024 results After-Market on Aug 08, 2024분석 기사 • Jul 12Is Codexis (NASDAQ:CDXS) Weighed On By Its Debt Load?Warren Buffett famously said, 'Volatility is far from synonymous with risk.' So it seems the smart money knows that...공시 • Jul 02Codexis, Inc. (NasdaqGS:CDXS) entered into an asset purchase agreement to acquire Gene Therapy Assets of Crosswalk Therapeutics.Codexis, Inc. (NasdaqGS:CDXS) entered into an asset purchase agreement to acquire Gene Therapy Assets of Crosswalk Therapeutics on July 1, 2024.분석 기사 • May 29Investors Appear Satisfied With Codexis, Inc.'s (NASDAQ:CDXS) ProspectsThere wouldn't be many who think Codexis, Inc.'s ( NASDAQ:CDXS ) price-to-sales (or "P/S") ratio of 3x is worth a...공시 • May 15Codexis, Inc. Presents Enzymatic Synthesis Data at TIDES USA Annual Meeting and Launches RNA Ligase Screening and Optimization ServicesCodexis, Inc. announced it has successfully synthesized an oligonucleotide via an enzymatic route to support RNA-based therapeutics manufacturing. Data highlighting this historic manufacturing milestone are being presented on May 14, 2024 in a Spotlight Presentation at the TIDES USA annual meeting taking place in Boston, MA, and virtually May 14 – 17, 2024. Codexis Enzymatically Synthesizes Fully Modified RNA Oligonucleotide: During the presentation, Codexis will showcase data on the enzymatic synthesis of a known siRNA oligonucleotide that incorporates the nucleotide modifications most frequently found in approved therapeutic assets today. This includes the synthesis of siRNA compounds using the Company’s Enzyme Catalyzed Oligonucleotide (ECO) Synthesis manufacturing platform from a starter oligonucleotide to the inclusion of a conjugation moiety. This final step primes the oligonucleotide for the attachment of a customer’s proprietary targeting moiety to enable direct delivery of the therapeutic agent to the desired cells. Key data from the presentation noted that the ECO Synthesis manufacturing platform: Incorporated RNA bases with common modifications used in current siRNA therapeutic assets; Achieved coupling efficiency greater than 98%; Executed the enzymatic addition of a conjugation moiety; and Confirmed lack of notable impurities typically observed in phosphoramidite chemistry synthesis. Now that Codexis has successfully achieved this important technical milestone, the Company is continuing process development to optimize yield, purity and quality with the goal of providing customers with siRNA material of comparable or better quality to phosphoramidite chemistry for preclinical testing. Codexis Launches RNA Ligase Screening and Optimization Services: Codexis also on May 14, 2024 announced the launch of its RNA Ligase Screening and Optimization Services. An overview of this new offering will be highlighted during a TIDES Talk session on Thursday, May 16, 2024. During phosphoramidite chemical synthesis of RNA, each nucleotide added to the growing oligonucleotide amplifies inherent coupling errors, leading to a decrease in the yield of the desired full-length RNA construct. By utilizing a ligation approach, multiple short, single-stranded RNA (ssRNA) fragments can be synthesized, via phosphoramidite chemistry or the ECO Synthesis manufacturing platform, then duplexed and ligated together with an ecoRNA double-stranded ligase to form the desired double-stranded RNA (dsRNA) construct. This method provides the potential for higher purity and yield, which allows for increased scalability and reduced manufacturing costs. As part of Codexis’ Center of Excellence for Enzymatic RNA Synthesis, the Company provides RNA ligase screening and optimization services, which include the custom evolution of dsRNA ligase enzyme variants, screening and protocol optimization for manufacturing and use of the dsRNA ligase, and research-grade RNA production, which can be used for future preclinical studies.Reported Earnings • May 03First quarter 2024 earnings: EPS and revenues exceed analyst expectationsFirst quarter 2024 results: US$0.17 loss per share (improved from US$0.34 loss in 1Q 2023). Revenue: US$17.1m (up 32% from 1Q 2023). Net loss: US$11.5m (loss narrowed 49% from 1Q 2023). Revenue exceeded analyst estimates by 28%. Earnings per share (EPS) also surpassed analyst estimates by 13%. Revenue is forecast to grow 14% p.a. on average during the next 3 years, compared to a 6.5% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 49% per year but the company’s share price has only fallen by 41% per year, which means it has not declined as severely as earnings.공시 • May 03Codexis, Inc. Reiterates Financial Guidance for the Fiscal 2024Codexis, Inc. reiterated financial guidance for the fiscal 2024. For the period, the company product revenues are expected to be in the range of $38 million to $42 million, excluding revenue related to PAXLOVID™. R&D revenues are expected to be in the range of $18 million to $22 million.공시 • Apr 28Codexis, Inc., Annual General Meeting, Jun 11, 2024Codexis, Inc., Annual General Meeting, Jun 11, 2024, at 09:00 Pacific Standard Time. Agenda: To elect the two Class II directors nominees identified in the accompanying proxy statement to hold office until the 2027 annual meeting of stockholders; to ratify the selection by the Audit Committee of the board of directors of KPMG LLP as an independent registered public accounting firm for the fiscal year ending December 31, 2024; to approve, on a non-binding, advisory basis, the compensation of named executive officers; and transact such other business as may properly come before the Annual Meeting.공시 • Apr 20Codexis, Inc. to Report Q1, 2024 Results on May 02, 2024Codexis, Inc. announced that they will report Q1, 2024 results After-Market on May 02, 2024공시 • Apr 11Codexis, Inc. Appoints Carole Cobb to Its Strategic Advisory BoardCodexis, Inc. announced the appointment of Carole Cobb, MBA, to the Company’s Strategic Advisory Board (SAB). Ms. Cobb is the former Chief Operating Officer at GreenLight Biosciences, a bio-performance company developing RNA-based solutions for agriculture and pharmaceutical applications. Her deep biotechnology experience includes leadership roles across fermentation-based commercial manufacturing, process development, plant operations and global supply chain management. Ms. Cobb has forty years of bio-based industry experience and is currently a business consultant for biotechnology companies. Most recently, she served as the Chief Operating Officer at GreenLight Biosciences where she led the Company’s efforts to scale their proprietary bioprocessing methods. Prior to joining GreenLight, Ms. Cobb served as Chief Operating Officer at Cobalt Technologies. Earlier in her career, Ms. Cobb held senior leadership roles at Danisco A/S and Genencor International. She holds a Master of Business Administration from the University of Rochester and Bachelor of Science degrees in Chemical Engineering, Biochemistry and Cell & Molecular Biology from the State University of New York at Buffalo. Current members include John Maraganore, PhD, founder and former Chief Executive Officer of Alnylam Pharmaceuticals; Masad Damha, PhD, Distinguished James McGill Professor at McGill University; Jim Lalonde, PhD, biotechnology consultant for start-up companies in enzyme engineering and former Senior Vice President of Research and Development at Codexis; and Carole Cobb, MBA, biotechnology consultant and former Chief Operating Officer at GreenLight Biosciences.Major Estimate Revision • Mar 06Consensus revenue estimates increase by 12%The consensus outlook for revenues in fiscal year 2024 has improved. 2024 revenue forecast increased from US$58.5m to US$65.4m. Forecast losses expected to reduce from -US$0.672 to -US$0.646 per share. Life Sciences industry in the US expected to see average net income growth of 12% next year. Consensus price target of US$6.57 unchanged from last update. Share price fell 2.2% to US$3.64 over the past week.Board Change • Mar 01High number of new directorsThere are 5 new directors who have joined the board in the last 3 years. Member of Strategic Advisory Board John M. Maraganore was the last director to join the board, commencing their role in 2024. The company’s lack of board continuity is considered a risk according to the Simply Wall St Risk Model.Reported Earnings • Feb 29Full year 2023 earnings: EPS and revenues exceed analyst expectationsFull year 2023 results: US$1.12 loss per share (further deteriorated from US$0.51 loss in FY 2022). Revenue: US$70.1m (down 49% from FY 2022). Net loss: US$76.2m (loss widened 127% from FY 2022). Revenue exceeded analyst estimates by 14%. Earnings per share (EPS) also surpassed analyst estimates by 5.0%. Revenue is forecast to grow 16% p.a. on average during the next 3 years, compared to a 6.1% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 48% per year but the company’s share price has only fallen by 39% per year, which means it has not declined as severely as earnings.공시 • Feb 21Codexis, Inc Appoints Masad Damha, PhD and Jim Lalonde, PhD to Strategic Advisory BoardCodexis, Inc. announced the appointment of Masad Damha, PhD, and Jim Lalonde, PhD, to the Company’s Strategic Advisory Board (SAB), joining John Maraganore, PhD, the founder and former Chief Executive Officer of Alnylam Pharmaceuticals. This board is now comprised of experts across oligonucleotide synthesis and manufacturing and was established to help guide the Company’s strategic direction, providing critical insights to inform the continued development of Codexis’ ECO Synthesis™ manufacturing platform. Masad Damha, PhD, is the Distinguished James McGill Professor at McGill University. His research has been instrumental in the development of new therapeutic drugs based on RNA targeting and gene editing, and he has authored more than 200 publications. Dr. Damha is a co-founder of Anagenis, Inc., a start-up with proprietary antisense technologies (ANA and FANA). His FANA technology is being applied by multiple research laboratories and industries to assess and develop modified oligonucleotides against several biological targets, including cancer and infectious diseases. Dr. Damha has served as the President of both the International Society of Nucleosides, Nucleotides and Nucleic Acids and the Oligonucleotide Therapeutic Society, and currently serves on the Editorial Board of the journal Nucleic Acids Therapeutics. He received both his PhD and BSc in Organic Chemistry from McGill University. Jim Lalonde, PhD, is a biotechnology consultant for start-up companies in enzyme engineering and biotechnology. Presently, Dr. Lalonde serves as Chairman of the Board of Directors at Willow Biosciences and as a Scientific Advisory Board member at Bota Biosciences, bitBiome, Curie Co. and Invizyne. Most recently, Dr. Lalonde served as the head of the Microbial Digital Genome Engineering Business at Inscripta. Prior to Inscripta, he spent nearly 15 years at Codexis, culminating in the role of Senior Vice President of Research and Development, where he oversaw the development of more than 50 enzymes for biotherapeutics, drug manufacturing, nutrition and molecular diagnostics applications. Earlier in his career, Dr. Lalonde held leadership roles in biocatalysis and chemical development at Altus Biologics and in scientific research at Vista Chemical Company. Dr. Lalonde earned a PhD in Organic Chemistry from Texas A&M University and a BS in Chemistry from Lakehead University.공시 • Feb 17Codexis, Inc. Announces Not to Stand for Reelection of Jennifer Aaker as Board of DirectorCodexis, Inc. announced on February 13, 2024, Jennifer Aaker, Ph.D. provided notice to the board of directors of Codexis, Inc. of her intention not to stand for reelection to the Board at the expiration of her current term at the company’s 2024 Annual Meeting of Stockholders (the 2024 Annual Meeting). Dr. Aaker’s decision not to stand for reelection is not the result of any disagreement with the company on any matter relating to its operations, policies, practices or otherwise. Dr. Aaker will remain a director until the 2024 Annual Meeting.공시 • Feb 15+ 1 more updateCodexis, Inc. to Report Q4, 2023 Results on Feb 28, 2024Codexis, Inc. announced that they will report Q4, 2023 results After-Market on Feb 28, 2024New Risk • Feb 07New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 17% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risk Share price has been highly volatile over the past 3 months (17% average weekly change). Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$19m net loss in 3 years). Shareholders have been diluted in the past year (6.3% increase in shares outstanding).공시 • Feb 02seqWell and Codexis to Unveil Engineered Transposase Enzyme for Genomics Applications at AGBT General MeetingseqWell and Codexis, Inc. announced the creation of an engineered high-performance transposase enzyme designed to drive superior performance in sequencing applications. The co-development of this new transposase enzyme - called TnX transposase - builds upon a multi-year partnership between the two companies, leveraging Codexis' strength in enzyme engineering, and seqWell's expertise in developing tools to improve next-generation sequencing (NGS) performance. Performance data highlighting this enzyme will be presented during the Advances in Genome Biology and Technology (AGBT) General Meeting being held February 5 - 8, 2024 in Orlando, Florida. This newly engineered transposase is designed to exhibit significantly lower bias, potentially providing more uniform coverage of sequenced DNA; improved activity, converting a higher percentage of DNA to library; and improved robustness across a range of assay conditions. seqWell plans to incorporate the TnX transposase into new NGS workflow kits currently in development.분석 기사 • Dec 20Codexis, Inc.'s (NASDAQ:CDXS) Shares Leap 56% Yet They're Still Not Telling The Full StoryCodexis, Inc. ( NASDAQ:CDXS ) shares have continued their recent momentum with a 56% gain in the last month alone. Not...분석 기사 • Dec 19What Does Codexis, Inc.'s (NASDAQ:CDXS) Share Price Indicate?Codexis, Inc. ( NASDAQ:CDXS ), might not be a large cap stock, but it received a lot of attention from a substantial...공시 • Dec 14Aldevron, LLC entered into an agreement to acquire global exclusive license for Codex® HiCap RNA Polymerase from Codexis, Inc. (NasdaqGS:CDXS).Aldevron, LLC entered into an agreement to acquire global exclusive license for Codex® HiCap RNA Polymerase from Codexis, Inc. (NasdaqGS:CDXS) on December 13, 2023. Under the terms of the deal, Aldevron will receive global manufacturing and commercialization rights to the Codex® HiCap RNA Polymerase and Codexis will receive payments for near-term technical milestones, along with commercial milestones and sales-based royalties.분석 기사 • Nov 15Is Codexis (NASDAQ:CDXS) In A Good Position To Deliver On Growth Plans?Just because a business does not make any money, does not mean that the stock will go down. For example, although...Major Estimate Revision • Nov 10Consensus EPS estimates fall by 15%The consensus outlook for earnings per share (EPS) in fiscal year 2023 has deteriorated. 2023 revenue forecast decreased from US$61.2m to US$60.6m. Losses expected to increase from US$1.03 per share to US$1.18. Life Sciences industry in the US expected to see average net income growth of 11% next year. Consensus price target down from US$7.43 to US$5.83. Share price fell 11% to US$1.60 over the past week.Price Target Changed • Nov 07Price target decreased by 17% to US$6.20Down from US$7.43, the current price target is an average from 5 analysts. New target price is 256% above last closing price of US$1.74. Stock is down 71% over the past year. The company is forecast to post a net loss per share of US$1.15 next year compared to a net loss per share of US$0.51 last year.Price Target Changed • Nov 05Price target increased by 13% to US$8.40Up from US$7.43, the current price target is an average from 5 analysts. New target price is 335% above last closing price of US$1.93. Stock is down 70% over the past year. The company is forecast to post a net loss per share of US$1.11 next year compared to a net loss per share of US$0.51 last year.Reported Earnings • Nov 03Third quarter 2023 earnings: EPS and revenues miss analyst expectationsThird quarter 2023 results: US$0.50 loss per share (further deteriorated from US$0.15 loss in 3Q 2022). Revenue: US$9.28m (down 73% from 3Q 2022). Net loss: US$34.9m (loss widened 249% from 3Q 2022). Revenue missed analyst estimates by 7.5%. Earnings per share (EPS) also missed analyst estimates by 54%. Revenue is forecast to grow 16% p.a. on average during the next 3 years, compared to a 3.8% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 42% per year but the company’s share price has fallen by 49% per year, which means it is performing significantly worse than earnings.공시 • Nov 03Codexis, Inc. Reiterates Earnings Guidance for the Year 2023Codexis, Inc. reiterated earnings guidance for the year 2023. Codexis reiterated its 2023 financial guidance ranges originally issued on July 20, 2023, and reiterated on August 3, 2023, as follows: Product revenues are expected to be in the range of $30 million to $35 million, excluding enzyme sales related to PAXLOVID™. R&D revenues are expected to be in the range of $21 million to $24 million.공시 • Oct 28Codexis, Inc. to Present Update on Eco Synthesis Platform At Tides EuropeCodexis, Inc. announced a presentation highlighting the role of an enzymatic approach to support RNA-based therapeutics manufacturing at the TIDES Europe annual meeting taking place in Amsterdam, Netherlands and virtually October 30- November 1, 2023. During the presentation, Codexis will showcase how engineered enzymes can complement traditional chemical synthesis methods by addressing scalability, cost and waste challenges associated with commercial-scale production. The Company will also showcase its technical progress on its Enzyme-Catalyzed Oligonucleotide (ECO) Synthesis(TM) technology platform, being developed to enable an enzymatic route of nucleic acid synthesis. The presentation will be held live and virtually on November 1, 2023. The Company will make a video recap of the TIDES Europe presentation available on its website following the conclusion of the meeting. About the ECO Synthesis(TM) Platform Ribonucleic acid (RNA) as a therapeutic modality has gained tremendous traction in recent years with the growing number of messenger RNA (mRNA) vaccines and small interfering RNA (siRNA) candidates advancing in clinical studies. However, large-scale production of RNAi therapeutics using traditional chemical synthesis faces complex challenges in nucleic acids quality and quantity, as well as overall economics. With over 450 RNA interference (RNAi) therapies currently in clinical development, including more than 40 assets in Phase 2 and Phase 3 clinical trials targeting disease indications impacting millions of patients, RNAi therapeutic demand is projected to outpace current production capabilities by the end of the decade. Codexis' proprietary ECO Synthesis(TM") technology platform is being designed to address these scalability and cost limitations by potentially enabling the commercial-scale manufacture of RNAi therapeutics through an enzymatic route. The Company is on track to demonstrate gram-scale synthesis by the end of 2023, where it will demonstrate the preparative-scale manufacture of an oligonucleotide, composed of the modified nucleotide building blocks typically used in RNAi therapeutics, under process-like conditions.공시 • Oct 20Codexis, Inc. to Report Q3, 2023 Results on Nov 02, 2023Codexis, Inc. announced that they will report Q3, 2023 results After-Market on Nov 02, 2023공시 • Jul 23+ 2 more updatesCodexis, Inc. to Report Q2, 2023 Results on Aug 03, 2023Codexis, Inc. announced that they will report Q2, 2023 results at 4:00 PM, US Eastern Standard Time on Aug 03, 2023분석 기사 • Jun 28Lacklustre Performance Is Driving Codexis, Inc.'s (NASDAQ:CDXS) Low P/SWith a price-to-sales (or "P/S") ratio of 1.5x Codexis, Inc. ( NASDAQ:CDXS ) may be sending very bullish signals at the...New Risk • Jun 16New minor risk - Share price stabilityThe company's share price has been volatile over the past 3 months. It is more volatile than 75% of American stocks, typically moving 10% a week. This is considered a minor risk. Share price volatility indicates the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. It also increases the risk of potential losses in the short term as the stock tends to have larger drops in price more frequently than other stocks. Currently, the following risks have been identified for the company: Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$48m net loss in 3 years). Share price has been volatile over the past 3 months (10% average weekly change). Shareholders have been diluted in the past year (2.2% increase in shares outstanding).분석 기사 • Jun 07Calculating The Intrinsic Value Of Codexis, Inc. (NASDAQ:CDXS)Key Insights Codexis' estimated fair value is US$2.68 based on 2 Stage Free Cash Flow to Equity With US$2.63 share...Price Target Changed • May 18Price target decreased by 7.1% to US$11.14Down from US$12.00, the current price target is an average from 7 analysts. New target price is 317% above last closing price of US$2.67. Stock is down 74% over the past year. The company is forecast to post a net loss per share of US$1.04 next year compared to a net loss per share of US$0.51 last year.공시 • May 11Codexis, Inc. Unveils Eco Synthesis Platform for Large-Scale RNAi Therapeutics Production at Tides USACodexis, Inc. announced the unveiling of its Enzyme-Catalyzed Oligonucleotide (ECO) Synthesis(TM) technology, a proprietary new synthesis platform being developed for manufacturing RNA oligonucleotide therapeutics at scale. The ECO Synthesis(TM) technology was unveiled during a pre-conference workshop at the TIDES USA annual meeting, being held May 7-10, 2023, in San Diego, CA. Ribonucleic acid (RNA) as a therapeutic modality has gained tremendous traction in recent years with the growing number of messenger RNA (mRNA) vaccines and small interfering RNA (siRNA) product candidates advancing in clinical studies. However, large-scale production faces complex challenges in nucleic acids quality and quantity, as well as overall economics. By replacing phosphoramidite chemistry with enzymatic methods, Codexis' proprietary ECO Synthesis(TM)technology is specifically engineered to overcome these difficulties to enable scalable and sustainable manufacturing.분석 기사 • May 09At US$3.41, Is It Time To Put Codexis, Inc. (NASDAQ:CDXS) On Your Watch List?Codexis, Inc. ( NASDAQ:CDXS ), is not the largest company out there, but it saw significant share price movement during...Price Target Changed • May 08Price target decreased by 10% to US$11.57Down from US$12.88, the current price target is an average from 7 analysts. New target price is 239% above last closing price of US$3.41. Stock is down 66% over the past year. The company is forecast to post a net loss per share of US$0.96 next year compared to a net loss per share of US$0.51 last year.매출 및 비용 세부 내역Codexis가 돈을 벌고 사용하는 방법. 최근 발표된 LTM 실적 기준.순이익 및 매출 추이NasdaqGS:CDXS 매출, 비용 및 순이익 (USD Millions)날짜매출순이익일반관리비연구개발비31 Mar 2678-3244031 Dec 2570-4447030 Sep 2553-6449030 Jun 2557-6551031 Mar 2550-7455031 Dec 2459-6555030 Sep 2464-6254030 Jun 2461-7653031 Mar 2474-6551031 Dec 2370-7653030 Sep 2374-8253030 Jun 2399-5755031 Mar 23116-4852031 Dec 22139-3452030 Sep 22133-3152030 Jun 22135-1951031 Mar 22122-2154031 Dec 21105-2149030 Sep 21101-1546030 Jun 2183-2342031 Mar 2172-2537031 Dec 2069-2435030 Sep 2067-2134030 Jun 2070-1433031 Mar 2068-1432031 Dec 1968-1232030 Sep 1966-1231030 Jun 1961-1430031 Mar 1962-1130031 Dec 1861-1129030 Sep 1866-930030 Jun 1859-1831031 Mar 1856-2030031 Dec 1750-2329030 Sep 1738-2928030 Jun 1743-1825031 Mar 1749-925031 Dec 1649-925030 Sep 1650-524030 Jun 1653-125031 Mar 1643-924031 Dec 1542-822030 Sep 1544-521030 Jun 1534-15210양질의 수익: CDXS 은(는) 현재 수익성이 없습니다.이익 마진 증가: CDXS는 현재 수익성이 없습니다.잉여현금흐름 대비 순이익 분석과거 순이익 성장 분석수익추이: CDXS은 수익성이 없으며 지난 5년 동안 손실이 연평균 19.7% 증가했습니다.성장 가속화: 현재 수익성이 없어 지난 1년간 CDXS의 수익 성장률을 5년 평균과 비교할 수 없습니다.수익 대 산업: CDXS은 수익성이 없어 지난 해 수익 성장률을 Life Sciences 업계(3.8%)와 비교하기 어렵습니다.자기자본이익률높은 ROE: CDXS는 현재 수익성이 없으므로 자본 수익률이 음수(-73.99%)입니다.총자산이익률투하자본수익률우수한 과거 실적 기업을 찾아보세요7D1Y7D1Y7D1YPharmaceuticals-biotech 산업에서 과거 실적이 우수한 기업.View Financial Health기업 분석 및 재무 데이터 상태데이터최종 업데이트 (UTC 시간)기업 분석2026/05/16 09:20종가2026/05/15 00:00수익2026/03/31연간 수익2025/12/31데이터 소스당사의 기업 분석에 사용되는 데이터는 S&P Global Market Intelligence LLC에서 제공됩니다. 아래 데이터는 이 보고서를 생성하기 위해 분석 모델에서 사용됩니다. 데이터는 정규화되므로 소스가 제공된 후 지연이 발생할 수 있습니다.패키지데이터기간미국 소스 예시 *기업 재무제표10년손익계산서현금흐름표대차대조표SEC 양식 10-KSEC 양식 10-Q분석가 컨센서스 추정치+3년재무 예측분석가 목표주가분석가 리서치 보고서Blue Matrix시장 가격30년주가배당, 분할 및 기타 조치ICE 시장 데이터SEC 양식 S-1지분 구조10년주요 주주내부자 거래SEC 양식 4SEC 양식 13D경영진10년리더십 팀이사회SEC 양식 10-KSEC 양식 DEF 14A주요 개발10년회사 공시SEC 양식 8-K* 미국 증권에 대한 예시이며, 비(非)미국 증권에는 해당 국가의 규제 서식 및 자료원을 사용합니다.별도로 명시되지 않는 한 모든 재무 데이터는 연간 기간을 기준으로 하지만 분기별로 업데이트됩니다. 이를 TTM(최근 12개월) 또는 LTM(지난 12개월) 데이터라고 합니다. 자세히 알아보기.분석 모델 및 스노우플레이크이 보고서를 생성하는 데 사용된 분석 모델에 대한 자세한 내용은 당사의 Github 페이지에서 확인하실 수 있습니다. 또한 보고서 활용 방법에 대한 가이드와 YouTube 튜토리얼도 제공합니다.Simply Wall St 분석 모델을 설계하고 구축한 세계적 수준의 팀에 대해 알아보세요.산업 및 섹터 지표산업 및 섹터 지표는 Simply Wall St가 6시간마다 계산하며, 프로세스에 대한 자세한 내용은 Github에서 확인할 수 있습니다.분석가 소스Codexis, Inc.는 18명의 분석가가 다루고 있습니다. 이 중 7명의 분석가가 우리 보고서에 입력 데이터로 사용되는 매출 또는 수익 추정치를 제출했습니다. 분석가의 제출 자료는 하루 종일 업데이트됩니다.분석가기관J. HorwitzBairdVishal ShahBarclaysRobert WassermanBenchmark Company15명의 분석가 더 보기
Reported Earnings • May 11First quarter 2026 earnings: EPS and revenues exceed analyst expectationsFirst quarter 2026 results: US$0.096 loss per share (improved from US$0.25 loss in 1Q 2025). Revenue: US$15.2m (up 102% from 1Q 2025). Net loss: US$8.70m (loss narrowed 58% from 1Q 2025). Revenue exceeded analyst estimates by 5.0%. Earnings per share (EPS) also surpassed analyst estimates by 27%. Revenue is forecast to grow 20% p.a. on average during the next 3 years, compared to a 6.5% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has increased by 18% per year but the company’s share price has only increased by 1% per year, which means it is significantly lagging earnings growth.
공시 • Apr 23Codexis, Inc. to Report Q1, 2026 Results on May 07, 2026Codexis, Inc. announced that they will report Q1, 2026 results After-Market on May 07, 2026
Reported Earnings • Mar 12Full year 2025 earnings: EPS and revenues exceed analyst expectationsFull year 2025 results: US$0.51 loss per share (improved from US$0.89 loss in FY 2024). Revenue: US$70.4m (up 19% from FY 2024). Net loss: US$44.0m (loss narrowed 33% from FY 2024). Revenue exceeded analyst estimates by 4.6%. Earnings per share (EPS) also surpassed analyst estimates by 22%. Revenue is forecast to grow 22% p.a. on average during the next 3 years, compared to a 6.3% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has increased by 4% per year but the company’s share price has fallen by 25% per year, which means it is significantly lagging earnings.
공시 • Feb 25Codexis, Inc. to Report Q4, 2025 Results on Mar 11, 2026Codexis, Inc. announced that they will report Q4, 2025 results After-Market on Mar 11, 2026
공시 • Oct 23Codexis, Inc. to Report Q3, 2025 Results on Nov 06, 2025Codexis, Inc. announced that they will report Q3, 2025 results After-Market on Nov 06, 2025
Reported Earnings • Aug 14Second quarter 2025 earnings: EPS and revenues exceed analyst expectationsSecond quarter 2025 results: US$0.15 loss per share (improved from US$0.32 loss in 2Q 2024). Revenue: US$15.3m (up 92% from 2Q 2024). Net loss: US$13.3m (loss narrowed 42% from 2Q 2024). Revenue exceeded analyst estimates by 8.1%. Earnings per share (EPS) also surpassed analyst estimates by 15%. Revenue is forecast to grow 24% p.a. on average during the next 3 years, compared to a 6.0% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 20% per year but the company’s share price has fallen by 28% per year, which means it is performing significantly worse than earnings.
Price Target Changed • May 11Price target decreased by 7.1% to US$6.58Down from US$7.08, the current price target is an average from 6 analysts. New target price is 148% above last closing price of US$2.65. Stock is up 0.4% over the past year. The company is forecast to post a net loss per share of US$0.40 next year compared to a net loss per share of US$0.50 last year.
분석 기사 • May 11US$6.58: That's What Analysts Think Codexis, Inc. (NASDAQ:CDXS) Is Worth After Its Latest ResultsA week ago, Codexis, Inc. ( NASDAQ:CDXS ) came out with a strong set of quarterly numbers that could potentially lead...
Reported Earnings • May 11First quarter 2026 earnings: EPS and revenues exceed analyst expectationsFirst quarter 2026 results: US$0.096 loss per share (improved from US$0.25 loss in 1Q 2025). Revenue: US$15.2m (up 102% from 1Q 2025). Net loss: US$8.70m (loss narrowed 58% from 1Q 2025). Revenue exceeded analyst estimates by 5.0%. Earnings per share (EPS) also surpassed analyst estimates by 27%. Revenue is forecast to grow 20% p.a. on average during the next 3 years, compared to a 6.5% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has increased by 18% per year but the company’s share price has only increased by 1% per year, which means it is significantly lagging earnings growth.
공시 • Apr 30Codexis, Inc., Annual General Meeting, Jun 17, 2026Codexis, Inc., Annual General Meeting, Jun 17, 2026.
Breakeven Date Change • Apr 26No longer forecast to breakevenThe 7 analysts covering Codexis no longer expect the company to break even during the foreseeable future. The company was expected to make a profit of US$20.0m in 2028. New consensus forecast suggests the company will make a loss of US$1.11m in 2028.
공시 • Apr 23Codexis, Inc. to Report Q1, 2026 Results on May 07, 2026Codexis, Inc. announced that they will report Q1, 2026 results After-Market on May 07, 2026
Reported Earnings • Mar 12Full year 2025 earnings: EPS and revenues exceed analyst expectationsFull year 2025 results: US$0.51 loss per share (improved from US$0.89 loss in FY 2024). Revenue: US$70.4m (up 19% from FY 2024). Net loss: US$44.0m (loss narrowed 33% from FY 2024). Revenue exceeded analyst estimates by 4.6%. Earnings per share (EPS) also surpassed analyst estimates by 22%. Revenue is forecast to grow 22% p.a. on average during the next 3 years, compared to a 6.3% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has increased by 4% per year but the company’s share price has fallen by 25% per year, which means it is significantly lagging earnings.
공시 • Mar 12Codexis, Inc. Provides Earnings Guidance for Full Year 2026Codexis, Inc. provided earnings guidance for full year 2026. The company expects total revenues are expected to be in the range of $72 million to $76 million.
공시 • Feb 25Codexis, Inc. to Report Q4, 2025 Results on Mar 11, 2026Codexis, Inc. announced that they will report Q4, 2025 results After-Market on Mar 11, 2026
New Risk • Feb 24New minor risk - Market cap sizeThe company's market capitalization is less than US$100m. Market cap: US$96.6m This is considered a minor risk. Companies with a small market capitalization are most likely businesses that have not yet released a product to market or are simply a very small company without a wide reach. Either way, risk is elevated with these companies because there is a chance the product may not come to fruition or the company's addressable market or demand may not be as large as expected. In addition, if the company's size is the main factor, it is less likely to have many investors and analysts following it and scrutinizing its performance and outlook. Currently, the following risks have been identified for the company: Minor Risks Less than 1 year of cash runway based on current free cash flow (-US$62m). Market cap is less than US$100m (US$96.6m market cap).
분석 기사 • Feb 12Positive Sentiment Still Eludes Codexis, Inc. (NASDAQ:CDXS) Following 29% Share Price SlumpCodexis, Inc. ( NASDAQ:CDXS ) shareholders that were waiting for something to happen have been dealt a blow with a 29...
Breakeven Date Change • Feb 06Forecast to breakeven in 2028The 6 analysts covering Codexis expect the company to break even for the first time. New consensus forecast suggests the company will make a profit of US$20.0m in 2028. Average annual earnings growth of 61% is required to achieve expected profit on schedule.
Board Change • Feb 06High number of new directorsThere are 6 new directors who have joined the board in the last 3 years. President, CEO & Director Alison Moore was the last director to join the board, commencing their role in 2025. The company’s lack of board continuity is considered a risk according to the Simply Wall St Risk Model.
공시 • Nov 07+ 2 more updatesCodexis, Inc. Announces Workforce ReductionIn November 2025, Codexis eliminated 46 positions, or approximately 24% of its workforce. The company expects to recognize an additional expense of approximately $3.5 million in the fourth quarter of 2025.
공시 • Oct 23Codexis, Inc. to Report Q3, 2025 Results on Nov 06, 2025Codexis, Inc. announced that they will report Q3, 2025 results After-Market on Nov 06, 2025
Seeking Alpha • Sep 16Codexis Weighs ECO Scale As Cash Runway TightensSummary Codexis is considering shifting from enzyme supply to ECO Synthesis. This way, they could target siRNA as a near-term commercial wedge with engineered ligases. ECO could convert lab projects into GLP, then GMP supply. So far, 3 CDMOs have already replicated Codexis’s ligation processes, which bodes well for CDXS. However, in the near term, management may prioritize scaling up ECO over reaching breakeven. This is a risk, given their cash runway is somewhat tight already. After all, CDXS’s liquidity could become strained with potential added CAPEX for capacity and staffing if they pursue ECO growth. Overall, I think their valuation is reasonable at this stage, but the cash burn risks nudge me towards a neutral rating on CDXS until we see further growth. Read the full article on Seeking Alpha
Reported Earnings • Aug 14Second quarter 2025 earnings: EPS and revenues exceed analyst expectationsSecond quarter 2025 results: US$0.15 loss per share (improved from US$0.32 loss in 2Q 2024). Revenue: US$15.3m (up 92% from 2Q 2024). Net loss: US$13.3m (loss narrowed 42% from 2Q 2024). Revenue exceeded analyst estimates by 8.1%. Earnings per share (EPS) also surpassed analyst estimates by 15%. Revenue is forecast to grow 24% p.a. on average during the next 3 years, compared to a 6.0% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 20% per year but the company’s share price has fallen by 28% per year, which means it is performing significantly worse than earnings.
공시 • Jul 31Codexis, Inc. to Report Q2, 2025 Results on Aug 13, 2025Codexis, Inc. announced that they will report Q2, 2025 results After-Market on Aug 13, 2025
분석 기사 • Jul 03What You Can Learn From Codexis, Inc.'s (NASDAQ:CDXS) P/SWhen you see that almost half of the companies in the Life Sciences industry in the United States have price-to-sales...
공시 • May 22Codexis, Inc. Presents Data at the Tides USA Annual Meeting in San Diego, CaliforniaCodexis, Inc. presented data at the TIDES USA annual meeting in San Diego, California. Codexis' presentations showcased its proprietary ECO Synthesis platform's ability to support siRNA manufacturing by reducing purification costs, improving process performance, and demonstrating the potential to control stereochemistry. During an oral Main Stage presentation, Codexis used inclisiran as an example to showcase how the use of mobilized enzymes in its ECO Synthesis platform delivers a consistent process with improved performance. Using sequential enzymatic synthesis, company: Continued to achieve consistent coupling efficiency of >98% Maintained the delivery of high product quality; Successfully decreased average cycle time by approximately 24%, translating into reduced production time; Demonstrated high yields of 30 grams of siRNA per liter. Using Codexis' ligase to manufacture siRNA, company data demonstrated the potential to reduce or eliminate costly downstream purification steps. This benefit of ligation has led many companies to explore using this method in siRNA manufacturing. The company's poster presentation highlighted how the Company's recently launched machine learning tool is improving the success rate of ligation to produce siRNA. The tool aids process design by guiding the selection of optimal pairings of ligases and RNA fragments and has been shown to significantly outperform traditional fragment selection by four to sixfold. By accelerating the ligase selection process and maximizing ligation efficiency, this tool demonstrates the potential to reduce process development time, lower costs, and enable an efficient manufacturing process for customers. Three CDMO Collaborator Presentations feature the Use of Codexis Ligases to Combine Short RNA Fragments: In addition to Codexis' presentations, Bachem, Nitto Avecia, and ST Pharm, three leading CDMOs in siRNA manufacturing, presented data on the use of Codexis ligases to successfully combine short RNA fragments. In a separate TIDES Talk presentation, Codexis highlighted a new feature under development for the ECO Synthesis technology to allow for stereochemical control during oligonucleotide synthesis. In contrast, the data in this oral presentation demonstrate how the ECO Synthesis platform can enable control over stereochemistry under process-relevant conditions.
분석 기사 • May 17Codexis, Inc. (NASDAQ:CDXS) Just Released Its First-Quarter Results And Analysts Are Updating Their EstimatesCodexis, Inc. ( NASDAQ:CDXS ) missed earnings with its latest first-quarter results, disappointing overly-optimistic...
New Risk • May 15New major risk - Financial positionThe company has less than a year of cash runway based on its current free cash flow trend. Free cash flow: -US$60m This is considered a major risk. With less than a year's worth of cash, the company will need to raise capital or take on debt unless its cash flows improve. This would dilute existing shareholders or increase balance sheet risk. Currently, the following risks have been identified for the company: Major Risk Less than 1 year of cash runway based on free cash flow trend (-US$60m free cash flow). Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$9.9m net loss in 3 years). Share price has been volatile over the past 3 months (14% average weekly change). Shareholders have been diluted in the past year (17% increase in shares outstanding).
Reported Earnings • May 15First quarter 2025 earnings: EPS and revenues miss analyst expectationsFirst quarter 2025 results: US$0.25 loss per share (further deteriorated from US$0.17 loss in 1Q 2024). Revenue: US$7.54m (down 56% from 1Q 2024). Net loss: US$20.7m (loss widened 80% from 1Q 2024). Revenue missed analyst estimates by 22%. Earnings per share (EPS) also missed analyst estimates by 5.4%. Revenue is forecast to grow 24% p.a. on average during the next 3 years, compared to a 6.0% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 30% per year but the company’s share price has fallen by 38% per year, which means it is performing significantly worse than earnings.
공시 • May 15Codexis, Inc. Reiterates Earnings Guidance for Full-Year 2025Codexis, Inc. Reiterated earnings guidance for full-year 2025. The company expects total revenues to be in the range of $64 million to $68 million.
공시 • May 01Codexis, Inc. to Report Q1, 2025 Results on May 14, 2025Codexis, Inc. announced that they will report Q1, 2025 results After-Market on May 14, 2025
공시 • Apr 28Codexis, Inc., Annual General Meeting, Jun 10, 2025Codexis, Inc., Annual General Meeting, Jun 10, 2025.
공시 • Apr 10Codexis, Inc. Announces Retirement of Byron L. Dorgan as DirectorOn April 4, 2025, Byron L. Dorgan provided notice to the board of directors of Codexis, Inc. of his intention to retire and not to stand for reelection to the Board at the expiration of his current term at the Company’s 2025 Annual Meeting of Stockholders (the “2025 Annual Meeting”). Mr. Dorgan’s decision not to stand for reelection is not the result of any disagreement with the Company on any matter relating to its operations, policies, practices or otherwise. Mr. Dorgan will remain a director until the 2025 Annual Meeting. Mr. Dorgan joined the Board in 2011, served as Chairman from 2021 through 2024, and currently serves as the Chair of the Nominating and Corporate Governance Committee. He will remain a consultant to Codexis for one year following his departure from the Board.
공시 • Apr 01Codexis, Inc. Appoints Cynthia Collins to the Board of DirectorsCodexis, Inc. announced the appointment of Cynthia Collins to the company’s board of directors. Cynthia Collins is a recognized leader with more than four decades of experience working in the pharmaceutical and biotech industry. She currently serves as Executive Chair and interim CEO of Nutcracker Therapeutics, a contract, research, development and manufacturing organization with a next generation RNA precision manufacturing platform. Previously, she was the CEO of Editas Medicine, a premier CRISPR company where she oversaw the first clinical trial administration of an in vivo CRISPR gene editing therapy. Her other notable roles include CEO of Human Longevity, CEO and general manager of various life science businesses at GE Healthcare, CEO of GenVec, group vice president at Beckman Coulter, CEO of Sequoia Pharmaceuticals, and president of oncology at Baxter Healthcare. Ms. Collins also currently serves as a board member at Certara, MaxCyte, DermTech, Alanis Therapeutics, Draper Laboratories, and Foundation for mRNA Medicines. She holds a bachelor’s degree in microbiology from the University of Illinois Urbana-Champaign and an MBA from the University of Chicago Booth School of Business.
새로운 내러티브 • Mar 29ECO Synthesis Launch In 2025 Will Unlock Pharma Contracts Transitioning to commercial execution with ECO Synthesis and partnerships enhances revenue growth by securing new contracts and expanding into pharma and biotech segments.
분석 기사 • Mar 28Codexis, Inc. (NASDAQ:CDXS) Stocks Pounded By 27% But Not Lagging Industry On Growth Or PricingUnfortunately for some shareholders, the Codexis, Inc. ( NASDAQ:CDXS ) share price has dived 27% in the last thirty...
Breakeven Date Change • Mar 07Forecast to breakeven in 2027The 7 analysts covering Codexis expect the company to break even for the first time. New consensus forecast suggests losses will reduce by 25% per year to 2026. The company is expected to make a profit of US$5.11m in 2027. Average annual earnings growth of 56% is required to achieve expected profit on schedule.
New Risk • Mar 03New minor risk - ProfitabilityThe company is currently unprofitable and not forecast to become profitable over the next 3 years. Trailing 12-month net loss: US$65m Forecast net loss in 3 years: US$6.6m This is considered a minor risk. Companies that are not profitable are more likely to be burning through cash and less likely to be well established. Ultimately, shareholders want to see a good return on their investment and that generally comes from sharing in the company's profits. Without profits, the company is under pressure to grow significantly while potentially having to reduce costs and possibly needing to take on debt or raise capital to remain afloat. Currently, the following risks have been identified for the company: Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$6.6m net loss in 3 years). Share price has been volatile over the past 3 months (11% average weekly change). Shareholders have been diluted in the past year (18% increase in shares outstanding).
New Risk • Mar 01New minor risk - Share price stabilityThe company's share price has been volatile over the past 3 months. It is more volatile than 75% of American stocks, typically moving 9.2% a week. This is considered a minor risk. Share price volatility indicates the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. It also increases the risk of potential losses in the short term as the stock tends to have larger drops in price more frequently than other stocks. Currently, the following risks have been identified for the company: Minor Risks Share price has been volatile over the past 3 months (9.2% average weekly change). Shareholders have been diluted in the past year (16% increase in shares outstanding).
Breakeven Date Change • Feb 28Forecast to breakeven in 2027The 7 analysts covering Codexis expect the company to break even for the first time. New consensus forecast suggests losses will reduce by 23% per year to 2026. The company is expected to make a profit of US$5.11m in 2027. Average annual earnings growth of 58% is required to achieve expected profit on schedule.
공시 • Feb 28Codexis, Inc. Provides Earnings Guidance for 2025Codexis, Inc. provided earnings guidance for 2025. The company expects total revenues to be in the range of $64 million to $68 million.
공시 • Feb 14Codexis, Inc. to Report Q4, 2024 Results on Feb 27, 2025Codexis, Inc. announced that they will report Q4, 2024 results at 4:00 PM, US Eastern Standard Time on Feb 27, 2025
공시 • Feb 09Codexis, Inc. Appoints Arthur Levin to Strategic Advisory BoardCodexis, Inc. announced the appointment of Arthur Levin, PhD, to the Company’s Strategic Advisory Board (SAB). Dr. Levin is a founding member of Avidity Biosciences, and currently serves on its Board of Directors. He brings three decades of experience developing oligonucleotides to Codexis as it continues to onboard customers for its Enzyme Catalyzed Oligonucleotide (ECO) Synthesis™ manufacturing platform. In addition to his role on the Board of Directors, Dr. Levin previously held the positions of Distinguished Scientist, Strategic Leader and Chief Scientific Officer at Avidity. Dr. Levin is a highly regarded key opinion leader in the RNA therapeutics field who has led teams responsible for the development of many oligonucleotides. Prior to joining Avidity, Dr. Levin was the Executive Vice President of Research and Development at miRagen Therapeutics and held senior drug development roles at Ionis (formerly Isis) Pharmaceuticals and Santaris Pharmaceuticals. He has published more than 100 scientific articles and has authored several of the most cited reviews in the field. In addition to Codexis, he serves on the scientific advisory boards of multiple institutions. Dr. Levin received a doctorate in toxicology from the University of Rochester and holds a bachelor’s degree in biology from Muhlenberg College.
Buy Or Sell Opportunity • Jan 27Now 22% undervaluedOver the last 90 days, the stock has risen 48% to US$4.72. The fair value is estimated to be US$6.09, however this is not to be taken as a buy recommendation but rather should be used as a guide only. Revenue has declined by 22% over the last 3 years. Earnings per share has declined by 46%. For the next 3 years, revenue is forecast to grow by 21% per annum. Earnings are also forecast to grow by 48% per annum over the same time period.
공시 • Jan 17Codexis, Inc. Appoints Christos Richards to Board of DirectorsCodexis, Inc. announced the appointment of Christos Richards to the Company’s Board of Directors. Christos Richards brings over 30 years of global executive advisory and search experience for the biopharmaceutical and healthcare industry to Codexis. To date, he has completed more than 450 executive level assignments, including over 200 Board, CEO and CEO succession projects in the Life Sciences sector. He currently serves as Global Head of Healthcare and Life Sciences at Calibre One, a global executive search firm with offices across California as well as Chicago, New York and London. Mr. Richards serves clients from venture-backed startups to leading global enterprises in devices, diagnostics, agricultural biotechnology, animal health, tools, services and digital health sectors. He has spent 20 years as a partner with two prominent boutique search firms, including serving as Chief Executive Officer of Levin & Company. Mr. Richards previously served on the Board of Directors for Coherus BioSciences and is also an advisor for the University of California, San Francisco Innovation Ventures Entrepreneurship Center. He holds a diploma in hospitality management from Schweizerische Wirteschule in Lucerne/Davos, Switzerland.
Buy Or Sell Opportunity • Jan 08Now 22% undervaluedOver the last 90 days, the stock has risen 60% to US$4.76. The fair value is estimated to be US$6.09, however this is not to be taken as a buy recommendation but rather should be used as a guide only. Revenue has declined by 22% over the last 3 years. Earnings per share has declined by 46%. For the next 3 years, revenue is forecast to grow by 21% per annum. Earnings are also forecast to grow by 48% per annum over the same time period.
분석 기사 • Jan 06Estimating The Intrinsic Value Of Codexis, Inc. (NASDAQ:CDXS)Key Insights Using the 2 Stage Free Cash Flow to Equity, Codexis fair value estimate is US$6.13 With US$5.43 share...
분석 기사 • Dec 10Is Codexis (NASDAQ:CDXS) Using Debt In A Risky Way?Some say volatility, rather than debt, is the best way to think about risk as an investor, but Warren Buffett famously...
공시 • Nov 15Codexis, Inc. Unveils Pioneering Enzymatic Synthesis Data to Enable the Future Manufacturing of RNAi TherapeuticsCodexis, Inc. announced data from three presentations at the TIDES Europe annual meeting being held November 12-14, 2024, in Hamburg, Germany. The data demonstrate the Company’s rapid advancement of its Enzyme Catalyzed Oligonucleotide (ECO) Synthesis™ manufacturing platform and establish Codexis’ position at the forefront of enzymatic synthesis technology to enable to ongoing expansion of RNAi therapeutics. During an oral Spotlight Presentation, Codexis unveiled the successful end-to-end enzymatic synthesis of an entire approved siRNA therapeutic asset, inclisiran. Codexis enzymatically synthesized the full-length sense and antisense strands of the molecule, including the enzymatic incorporation of a tissue-targeting moiety to the sense strand. To date, this process has only been completed utilizing phosphoramidite chemistry, a process that involves the use of harsh chemical conditions and vast amounts of toxic organic solvents. By contrast, Codexis’ ECO Synthesis manufacturing platform operates under milder, aqueous conditions, that improves product quality and dramatically decreases chemical waste production. In addition to this fully enzymatic route of synthesis, the Company demonstrated similar outcomes utilizing three routes of enzymatic ligation to produce the siRNA therapeutic asset, combining oligonucleotide fragments made by sequential enzymatic synthesis and traditional phosphoramidite chemistry. Key data from the presentation include: Achieved incorporation efficiency of >98% during sequential enzymatic oligo synthesis. Successfully attached the tri-GalNAc tissue-targeting moiety by enzymatic ligation. Obtained full-length oligonucleotides of equal quality and yields, using ligation of short fragments made with enzymes or by traditional phosphoramidite chemistry. Now that Codexis has successfully achieved this unprecedented milestone, the Company will continue to optimize its process for robustness, scaled-up quantities and improved purity with the goal of providing customers with siRNA material of comparable or better quality to phosphoramidite chemistry. The Company anticipates ramping up manufacturing of siRNA in quantities for preclinical testing following the successful build out of its ECO Synthesis Innovation Lab at the end of this year. Two additional presentations focused on results of direct comparisons of Codexis’ engineered double-stranded RNA (dsRNA) ligases and wild-type (WT) enzymes when used to combine short oligonucleotide fragments to synthesize full-length siRNA therapeutic compounds. In a joint poster with Bachem, one of the world’s leading CDMOs in oligonucleotide manufacturing, the data provided compelling external validation of the superior performance of Codexis ligases over existing wild-type enzymes in use today. Codexis enzymes demonstrated superior performance over wild-type enzymes across both volumetric productivity and substrate versatility. These dsRNA ligases outperformed on multiple substrate designs and enabled a higher conversion rate of oligonucleotide fragments into siRNA at increased concentrations of raw materials. In a separate TIDES Talk presentation, Codexis demonstrated improved performance of its dsRNA ligase over WT enzymes based on real customer case studies executed through the Company’s RNA Ligase Screening and Optimization Services, launched in May 2024. Codexis’ engineered ligases delivered robust, in-process performance, including higher substrate loading, faster reaction times and improved conversation at elevated temperatures. These data demonstrate the Company’s ability to accelerate delivery of lead ligase variants to customers and optimize process conditions for a customer’s specific asset.
공시 • Nov 13Codexis, Inc. Appoints Raymond De Vré to Board of DirectorsCodexis, Inc. announced the appointment of Raymond De Vré, PhD, to the Company’s Board of Directors. Dr. De Vré brings over 20 years of executive-level experience to Codexis. He currently serves as Managing Director at RADV Advisory, an independent strategic and operational advisory company focused on investments in the global healthcare and contract development and manufacturing organization (CDMO) space. Prior to founding RADV Advisory, he was the Chief Executive Officer of PolyPeptide Group, a CDMO focused on peptide- and oligonucleotide-based therapies for pharmaceutical and biotech companies globally. Prior to PolyPeptide, Dr. De Vré held multiple senior leadership roles at Dr. Reddy’s Laboratories, including Senior Vice President, Head of Biologics, and served as a member of the Management Council. Earlier in his career, he was a Partner at McKinsey & Company, working mostly in the pharmaceutical and biotech practice. Dr. De Vré holds a PhD in Applied Physics from Stanford University and a master’s degree in engineering from Université Libre de Bruxelles.
분석 기사 • Nov 07Codexis, Inc.'s (NASDAQ:CDXS) 29% Jump Shows Its Popularity With InvestorsCodexis, Inc. ( NASDAQ:CDXS ) shareholders have had their patience rewarded with a 29% share price jump in the last...
New Risk • Nov 04New minor risk - Shareholder dilutionThe company's shareholders have been diluted in the past year. Increase in shares outstanding: 17% This is considered a minor risk. Shareholder dilution occurs when there is an increase in the number of shares on issue that is not proportionally distributed between all shareholders. Often due to the company raising equity capital or some options being converted into stock. All else being equal, if there are more shares outstanding then each existing share will be entitled to a lower proportion of the company's total earnings, thus reducing earnings per share (EPS). While dilution might not always result in lower EPS (like if the company is using the capital to fund an EPS accretive acquisition) in a lot cases it does, along with lower dividends per share and less voting power at shareholder meetings. Currently, the following risks have been identified for the company: Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$18m net loss in 3 years). Shareholders have been diluted in the past year (17% increase in shares outstanding).
Reported Earnings • Nov 01Third quarter 2024 earnings: Revenues exceed analysts expectations while EPS lags behindThird quarter 2024 results: US$0.29 loss per share (improved from US$0.50 loss in 3Q 2023). Revenue: US$12.8m (up 38% from 3Q 2023). Net loss: US$20.6m (loss narrowed 41% from 3Q 2023). Revenue exceeded analyst estimates by 12%. Earnings per share (EPS) missed analyst estimates by 21%. Revenue is forecast to grow 20% p.a. on average during the next 3 years, compared to a 6.5% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 46% per year but the company’s share price has fallen by 56% per year, which means it is performing significantly worse than earnings.
공시 • Oct 11Codexis, Inc. to Report Q3, 2024 Results on Oct 31, 2024Codexis, Inc. announced that they will report Q3, 2024 results After-Market on Oct 31, 2024
공시 • Oct 03Codexis, Inc. Announces Executive ChangesCodexis, Inc. announced an increase in its cash reserves through capital raises totaling $31 million via the Company’s existing at-the-market facility during the quarter ended September 30, 2024. In addition to the financing, the Company strengthened its management team through the appointments of Alison Moore, PhD, to the newly created role of Chief Technology Officer. The Company also announced the appointment of John Schiffhauer as Senior Vice President of Intellectual Property. Mr. Schiffhauer brings over 20 years of experience in legal operations and intellectual property at Intel, and most recently, Zymergen, to this newly created role focused on managing the Company’s complex IP portfolio and executing strategic partnerships around it. Alison Moore brings to Codexis significant experience as a biotechnology and pharmaceutical executive, including an extensive background in biomanufacturing. She is former Chief Technical Officer of Allogene Therapeutics, a pioneering clinical-stage company advancing CAR-T therapies. Prior to Allogene, she spent a total of 20 years at Amgen, most recently as Senior Vice President, Process Development, and including roles in Supply Chain and Manufacturing. Dr. Moore also has experience at Genentech as a Director in Chemistry, Manufacturing and Controls, and in Regulatory Affairs. Dr. Moore holds a bachelor’s degree in pharmacology with honors and a doctorate degree in cell biology from Manchester University, England.
Major Estimate Revision • Aug 19Consensus EPS estimates fall by 12%The consensus outlook for fiscal year 2024 has been updated. 2024 expected loss increased from -US$0.676 to -US$0.755 per share. Revenue forecast unchanged at US$65.1m. Life Sciences industry in the US expected to see average net income growth of 20% next year. Consensus price target of US$7.17 unchanged from last update. Share price rose 6.7% to US$3.01 over the past week.
Major Estimate Revision • Aug 15Consensus EPS estimates fall by 11%The consensus outlook for fiscal year 2024 has been updated. 2024 expected loss increased from -US$0.676 to -US$0.75 per share. Revenue forecast unchanged at US$65.2m. Life Sciences industry in the US expected to see average net income growth of 20% next year. Consensus price target of US$7.43 unchanged from last update. Share price fell 11% to US$2.81 over the past week.
Reported Earnings • Aug 09Second quarter 2024 earnings: Revenues exceed analysts expectations while EPS lags behindSecond quarter 2024 results: US$0.32 loss per share (further deteriorated from US$0.17 loss in 2Q 2023). Revenue: US$7.98m (down 63% from 2Q 2023). Net loss: US$22.8m (loss widened 98% from 2Q 2023). Revenue exceeded analyst estimates by 2.0%. Earnings per share (EPS) missed analyst estimates by 21%. Revenue is forecast to grow 19% p.a. on average during the next 3 years, compared to a 6.7% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 51% per year and the company’s share price has also fallen by 51% per year.
공시 • Aug 09Codexis, Inc. Reiterates Earnings Guidance for the Full Year 2024Codexis, Inc. reiterated earnings guidance for the full year 2024. For the year, Product revenues are expected to be in the range of $38 million to $42 million, excluding revenue related to PAXLOVID.
분석 기사 • Jul 26After Leaping 26% Codexis, Inc. (NASDAQ:CDXS) Shares Are Not Flying Under The RadarCodexis, Inc. ( NASDAQ:CDXS ) shares have continued their recent momentum with a 26% gain in the last month alone...
공시 • Jul 19Codexis, Inc. to Report Q2, 2024 Results on Aug 08, 2024Codexis, Inc. announced that they will report Q2, 2024 results After-Market on Aug 08, 2024
분석 기사 • Jul 12Is Codexis (NASDAQ:CDXS) Weighed On By Its Debt Load?Warren Buffett famously said, 'Volatility is far from synonymous with risk.' So it seems the smart money knows that...
공시 • Jul 02Codexis, Inc. (NasdaqGS:CDXS) entered into an asset purchase agreement to acquire Gene Therapy Assets of Crosswalk Therapeutics.Codexis, Inc. (NasdaqGS:CDXS) entered into an asset purchase agreement to acquire Gene Therapy Assets of Crosswalk Therapeutics on July 1, 2024.
분석 기사 • May 29Investors Appear Satisfied With Codexis, Inc.'s (NASDAQ:CDXS) ProspectsThere wouldn't be many who think Codexis, Inc.'s ( NASDAQ:CDXS ) price-to-sales (or "P/S") ratio of 3x is worth a...
공시 • May 15Codexis, Inc. Presents Enzymatic Synthesis Data at TIDES USA Annual Meeting and Launches RNA Ligase Screening and Optimization ServicesCodexis, Inc. announced it has successfully synthesized an oligonucleotide via an enzymatic route to support RNA-based therapeutics manufacturing. Data highlighting this historic manufacturing milestone are being presented on May 14, 2024 in a Spotlight Presentation at the TIDES USA annual meeting taking place in Boston, MA, and virtually May 14 – 17, 2024. Codexis Enzymatically Synthesizes Fully Modified RNA Oligonucleotide: During the presentation, Codexis will showcase data on the enzymatic synthesis of a known siRNA oligonucleotide that incorporates the nucleotide modifications most frequently found in approved therapeutic assets today. This includes the synthesis of siRNA compounds using the Company’s Enzyme Catalyzed Oligonucleotide (ECO) Synthesis manufacturing platform from a starter oligonucleotide to the inclusion of a conjugation moiety. This final step primes the oligonucleotide for the attachment of a customer’s proprietary targeting moiety to enable direct delivery of the therapeutic agent to the desired cells. Key data from the presentation noted that the ECO Synthesis manufacturing platform: Incorporated RNA bases with common modifications used in current siRNA therapeutic assets; Achieved coupling efficiency greater than 98%; Executed the enzymatic addition of a conjugation moiety; and Confirmed lack of notable impurities typically observed in phosphoramidite chemistry synthesis. Now that Codexis has successfully achieved this important technical milestone, the Company is continuing process development to optimize yield, purity and quality with the goal of providing customers with siRNA material of comparable or better quality to phosphoramidite chemistry for preclinical testing. Codexis Launches RNA Ligase Screening and Optimization Services: Codexis also on May 14, 2024 announced the launch of its RNA Ligase Screening and Optimization Services. An overview of this new offering will be highlighted during a TIDES Talk session on Thursday, May 16, 2024. During phosphoramidite chemical synthesis of RNA, each nucleotide added to the growing oligonucleotide amplifies inherent coupling errors, leading to a decrease in the yield of the desired full-length RNA construct. By utilizing a ligation approach, multiple short, single-stranded RNA (ssRNA) fragments can be synthesized, via phosphoramidite chemistry or the ECO Synthesis manufacturing platform, then duplexed and ligated together with an ecoRNA double-stranded ligase to form the desired double-stranded RNA (dsRNA) construct. This method provides the potential for higher purity and yield, which allows for increased scalability and reduced manufacturing costs. As part of Codexis’ Center of Excellence for Enzymatic RNA Synthesis, the Company provides RNA ligase screening and optimization services, which include the custom evolution of dsRNA ligase enzyme variants, screening and protocol optimization for manufacturing and use of the dsRNA ligase, and research-grade RNA production, which can be used for future preclinical studies.
Reported Earnings • May 03First quarter 2024 earnings: EPS and revenues exceed analyst expectationsFirst quarter 2024 results: US$0.17 loss per share (improved from US$0.34 loss in 1Q 2023). Revenue: US$17.1m (up 32% from 1Q 2023). Net loss: US$11.5m (loss narrowed 49% from 1Q 2023). Revenue exceeded analyst estimates by 28%. Earnings per share (EPS) also surpassed analyst estimates by 13%. Revenue is forecast to grow 14% p.a. on average during the next 3 years, compared to a 6.5% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 49% per year but the company’s share price has only fallen by 41% per year, which means it has not declined as severely as earnings.
공시 • May 03Codexis, Inc. Reiterates Financial Guidance for the Fiscal 2024Codexis, Inc. reiterated financial guidance for the fiscal 2024. For the period, the company product revenues are expected to be in the range of $38 million to $42 million, excluding revenue related to PAXLOVID™. R&D revenues are expected to be in the range of $18 million to $22 million.
공시 • Apr 28Codexis, Inc., Annual General Meeting, Jun 11, 2024Codexis, Inc., Annual General Meeting, Jun 11, 2024, at 09:00 Pacific Standard Time. Agenda: To elect the two Class II directors nominees identified in the accompanying proxy statement to hold office until the 2027 annual meeting of stockholders; to ratify the selection by the Audit Committee of the board of directors of KPMG LLP as an independent registered public accounting firm for the fiscal year ending December 31, 2024; to approve, on a non-binding, advisory basis, the compensation of named executive officers; and transact such other business as may properly come before the Annual Meeting.
공시 • Apr 20Codexis, Inc. to Report Q1, 2024 Results on May 02, 2024Codexis, Inc. announced that they will report Q1, 2024 results After-Market on May 02, 2024
공시 • Apr 11Codexis, Inc. Appoints Carole Cobb to Its Strategic Advisory BoardCodexis, Inc. announced the appointment of Carole Cobb, MBA, to the Company’s Strategic Advisory Board (SAB). Ms. Cobb is the former Chief Operating Officer at GreenLight Biosciences, a bio-performance company developing RNA-based solutions for agriculture and pharmaceutical applications. Her deep biotechnology experience includes leadership roles across fermentation-based commercial manufacturing, process development, plant operations and global supply chain management. Ms. Cobb has forty years of bio-based industry experience and is currently a business consultant for biotechnology companies. Most recently, she served as the Chief Operating Officer at GreenLight Biosciences where she led the Company’s efforts to scale their proprietary bioprocessing methods. Prior to joining GreenLight, Ms. Cobb served as Chief Operating Officer at Cobalt Technologies. Earlier in her career, Ms. Cobb held senior leadership roles at Danisco A/S and Genencor International. She holds a Master of Business Administration from the University of Rochester and Bachelor of Science degrees in Chemical Engineering, Biochemistry and Cell & Molecular Biology from the State University of New York at Buffalo. Current members include John Maraganore, PhD, founder and former Chief Executive Officer of Alnylam Pharmaceuticals; Masad Damha, PhD, Distinguished James McGill Professor at McGill University; Jim Lalonde, PhD, biotechnology consultant for start-up companies in enzyme engineering and former Senior Vice President of Research and Development at Codexis; and Carole Cobb, MBA, biotechnology consultant and former Chief Operating Officer at GreenLight Biosciences.
Major Estimate Revision • Mar 06Consensus revenue estimates increase by 12%The consensus outlook for revenues in fiscal year 2024 has improved. 2024 revenue forecast increased from US$58.5m to US$65.4m. Forecast losses expected to reduce from -US$0.672 to -US$0.646 per share. Life Sciences industry in the US expected to see average net income growth of 12% next year. Consensus price target of US$6.57 unchanged from last update. Share price fell 2.2% to US$3.64 over the past week.
Board Change • Mar 01High number of new directorsThere are 5 new directors who have joined the board in the last 3 years. Member of Strategic Advisory Board John M. Maraganore was the last director to join the board, commencing their role in 2024. The company’s lack of board continuity is considered a risk according to the Simply Wall St Risk Model.
Reported Earnings • Feb 29Full year 2023 earnings: EPS and revenues exceed analyst expectationsFull year 2023 results: US$1.12 loss per share (further deteriorated from US$0.51 loss in FY 2022). Revenue: US$70.1m (down 49% from FY 2022). Net loss: US$76.2m (loss widened 127% from FY 2022). Revenue exceeded analyst estimates by 14%. Earnings per share (EPS) also surpassed analyst estimates by 5.0%. Revenue is forecast to grow 16% p.a. on average during the next 3 years, compared to a 6.1% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 48% per year but the company’s share price has only fallen by 39% per year, which means it has not declined as severely as earnings.
공시 • Feb 21Codexis, Inc Appoints Masad Damha, PhD and Jim Lalonde, PhD to Strategic Advisory BoardCodexis, Inc. announced the appointment of Masad Damha, PhD, and Jim Lalonde, PhD, to the Company’s Strategic Advisory Board (SAB), joining John Maraganore, PhD, the founder and former Chief Executive Officer of Alnylam Pharmaceuticals. This board is now comprised of experts across oligonucleotide synthesis and manufacturing and was established to help guide the Company’s strategic direction, providing critical insights to inform the continued development of Codexis’ ECO Synthesis™ manufacturing platform. Masad Damha, PhD, is the Distinguished James McGill Professor at McGill University. His research has been instrumental in the development of new therapeutic drugs based on RNA targeting and gene editing, and he has authored more than 200 publications. Dr. Damha is a co-founder of Anagenis, Inc., a start-up with proprietary antisense technologies (ANA and FANA). His FANA technology is being applied by multiple research laboratories and industries to assess and develop modified oligonucleotides against several biological targets, including cancer and infectious diseases. Dr. Damha has served as the President of both the International Society of Nucleosides, Nucleotides and Nucleic Acids and the Oligonucleotide Therapeutic Society, and currently serves on the Editorial Board of the journal Nucleic Acids Therapeutics. He received both his PhD and BSc in Organic Chemistry from McGill University. Jim Lalonde, PhD, is a biotechnology consultant for start-up companies in enzyme engineering and biotechnology. Presently, Dr. Lalonde serves as Chairman of the Board of Directors at Willow Biosciences and as a Scientific Advisory Board member at Bota Biosciences, bitBiome, Curie Co. and Invizyne. Most recently, Dr. Lalonde served as the head of the Microbial Digital Genome Engineering Business at Inscripta. Prior to Inscripta, he spent nearly 15 years at Codexis, culminating in the role of Senior Vice President of Research and Development, where he oversaw the development of more than 50 enzymes for biotherapeutics, drug manufacturing, nutrition and molecular diagnostics applications. Earlier in his career, Dr. Lalonde held leadership roles in biocatalysis and chemical development at Altus Biologics and in scientific research at Vista Chemical Company. Dr. Lalonde earned a PhD in Organic Chemistry from Texas A&M University and a BS in Chemistry from Lakehead University.
공시 • Feb 17Codexis, Inc. Announces Not to Stand for Reelection of Jennifer Aaker as Board of DirectorCodexis, Inc. announced on February 13, 2024, Jennifer Aaker, Ph.D. provided notice to the board of directors of Codexis, Inc. of her intention not to stand for reelection to the Board at the expiration of her current term at the company’s 2024 Annual Meeting of Stockholders (the 2024 Annual Meeting). Dr. Aaker’s decision not to stand for reelection is not the result of any disagreement with the company on any matter relating to its operations, policies, practices or otherwise. Dr. Aaker will remain a director until the 2024 Annual Meeting.
공시 • Feb 15+ 1 more updateCodexis, Inc. to Report Q4, 2023 Results on Feb 28, 2024Codexis, Inc. announced that they will report Q4, 2023 results After-Market on Feb 28, 2024
New Risk • Feb 07New major risk - Share price stabilityThe company's share price has been highly volatile over the past 3 months. It is more volatile than 90% of American stocks, typically moving 17% a week. This is considered a major risk. Share price volatility increases the risk of potential losses in the short-term as the stock tends to have larger drops in price more frequently than other stocks. It may also indicate the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. Currently, the following risks have been identified for the company: Major Risk Share price has been highly volatile over the past 3 months (17% average weekly change). Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$19m net loss in 3 years). Shareholders have been diluted in the past year (6.3% increase in shares outstanding).
공시 • Feb 02seqWell and Codexis to Unveil Engineered Transposase Enzyme for Genomics Applications at AGBT General MeetingseqWell and Codexis, Inc. announced the creation of an engineered high-performance transposase enzyme designed to drive superior performance in sequencing applications. The co-development of this new transposase enzyme - called TnX transposase - builds upon a multi-year partnership between the two companies, leveraging Codexis' strength in enzyme engineering, and seqWell's expertise in developing tools to improve next-generation sequencing (NGS) performance. Performance data highlighting this enzyme will be presented during the Advances in Genome Biology and Technology (AGBT) General Meeting being held February 5 - 8, 2024 in Orlando, Florida. This newly engineered transposase is designed to exhibit significantly lower bias, potentially providing more uniform coverage of sequenced DNA; improved activity, converting a higher percentage of DNA to library; and improved robustness across a range of assay conditions. seqWell plans to incorporate the TnX transposase into new NGS workflow kits currently in development.
분석 기사 • Dec 20Codexis, Inc.'s (NASDAQ:CDXS) Shares Leap 56% Yet They're Still Not Telling The Full StoryCodexis, Inc. ( NASDAQ:CDXS ) shares have continued their recent momentum with a 56% gain in the last month alone. Not...
분석 기사 • Dec 19What Does Codexis, Inc.'s (NASDAQ:CDXS) Share Price Indicate?Codexis, Inc. ( NASDAQ:CDXS ), might not be a large cap stock, but it received a lot of attention from a substantial...
공시 • Dec 14Aldevron, LLC entered into an agreement to acquire global exclusive license for Codex® HiCap RNA Polymerase from Codexis, Inc. (NasdaqGS:CDXS).Aldevron, LLC entered into an agreement to acquire global exclusive license for Codex® HiCap RNA Polymerase from Codexis, Inc. (NasdaqGS:CDXS) on December 13, 2023. Under the terms of the deal, Aldevron will receive global manufacturing and commercialization rights to the Codex® HiCap RNA Polymerase and Codexis will receive payments for near-term technical milestones, along with commercial milestones and sales-based royalties.
분석 기사 • Nov 15Is Codexis (NASDAQ:CDXS) In A Good Position To Deliver On Growth Plans?Just because a business does not make any money, does not mean that the stock will go down. For example, although...
Major Estimate Revision • Nov 10Consensus EPS estimates fall by 15%The consensus outlook for earnings per share (EPS) in fiscal year 2023 has deteriorated. 2023 revenue forecast decreased from US$61.2m to US$60.6m. Losses expected to increase from US$1.03 per share to US$1.18. Life Sciences industry in the US expected to see average net income growth of 11% next year. Consensus price target down from US$7.43 to US$5.83. Share price fell 11% to US$1.60 over the past week.
Price Target Changed • Nov 07Price target decreased by 17% to US$6.20Down from US$7.43, the current price target is an average from 5 analysts. New target price is 256% above last closing price of US$1.74. Stock is down 71% over the past year. The company is forecast to post a net loss per share of US$1.15 next year compared to a net loss per share of US$0.51 last year.
Price Target Changed • Nov 05Price target increased by 13% to US$8.40Up from US$7.43, the current price target is an average from 5 analysts. New target price is 335% above last closing price of US$1.93. Stock is down 70% over the past year. The company is forecast to post a net loss per share of US$1.11 next year compared to a net loss per share of US$0.51 last year.
Reported Earnings • Nov 03Third quarter 2023 earnings: EPS and revenues miss analyst expectationsThird quarter 2023 results: US$0.50 loss per share (further deteriorated from US$0.15 loss in 3Q 2022). Revenue: US$9.28m (down 73% from 3Q 2022). Net loss: US$34.9m (loss widened 249% from 3Q 2022). Revenue missed analyst estimates by 7.5%. Earnings per share (EPS) also missed analyst estimates by 54%. Revenue is forecast to grow 16% p.a. on average during the next 3 years, compared to a 3.8% growth forecast for the Life Sciences industry in the US. Over the last 3 years on average, earnings per share has fallen by 42% per year but the company’s share price has fallen by 49% per year, which means it is performing significantly worse than earnings.
공시 • Nov 03Codexis, Inc. Reiterates Earnings Guidance for the Year 2023Codexis, Inc. reiterated earnings guidance for the year 2023. Codexis reiterated its 2023 financial guidance ranges originally issued on July 20, 2023, and reiterated on August 3, 2023, as follows: Product revenues are expected to be in the range of $30 million to $35 million, excluding enzyme sales related to PAXLOVID™. R&D revenues are expected to be in the range of $21 million to $24 million.
공시 • Oct 28Codexis, Inc. to Present Update on Eco Synthesis Platform At Tides EuropeCodexis, Inc. announced a presentation highlighting the role of an enzymatic approach to support RNA-based therapeutics manufacturing at the TIDES Europe annual meeting taking place in Amsterdam, Netherlands and virtually October 30- November 1, 2023. During the presentation, Codexis will showcase how engineered enzymes can complement traditional chemical synthesis methods by addressing scalability, cost and waste challenges associated with commercial-scale production. The Company will also showcase its technical progress on its Enzyme-Catalyzed Oligonucleotide (ECO) Synthesis(TM) technology platform, being developed to enable an enzymatic route of nucleic acid synthesis. The presentation will be held live and virtually on November 1, 2023. The Company will make a video recap of the TIDES Europe presentation available on its website following the conclusion of the meeting. About the ECO Synthesis(TM) Platform Ribonucleic acid (RNA) as a therapeutic modality has gained tremendous traction in recent years with the growing number of messenger RNA (mRNA) vaccines and small interfering RNA (siRNA) candidates advancing in clinical studies. However, large-scale production of RNAi therapeutics using traditional chemical synthesis faces complex challenges in nucleic acids quality and quantity, as well as overall economics. With over 450 RNA interference (RNAi) therapies currently in clinical development, including more than 40 assets in Phase 2 and Phase 3 clinical trials targeting disease indications impacting millions of patients, RNAi therapeutic demand is projected to outpace current production capabilities by the end of the decade. Codexis' proprietary ECO Synthesis(TM") technology platform is being designed to address these scalability and cost limitations by potentially enabling the commercial-scale manufacture of RNAi therapeutics through an enzymatic route. The Company is on track to demonstrate gram-scale synthesis by the end of 2023, where it will demonstrate the preparative-scale manufacture of an oligonucleotide, composed of the modified nucleotide building blocks typically used in RNAi therapeutics, under process-like conditions.
공시 • Oct 20Codexis, Inc. to Report Q3, 2023 Results on Nov 02, 2023Codexis, Inc. announced that they will report Q3, 2023 results After-Market on Nov 02, 2023
공시 • Jul 23+ 2 more updatesCodexis, Inc. to Report Q2, 2023 Results on Aug 03, 2023Codexis, Inc. announced that they will report Q2, 2023 results at 4:00 PM, US Eastern Standard Time on Aug 03, 2023
분석 기사 • Jun 28Lacklustre Performance Is Driving Codexis, Inc.'s (NASDAQ:CDXS) Low P/SWith a price-to-sales (or "P/S") ratio of 1.5x Codexis, Inc. ( NASDAQ:CDXS ) may be sending very bullish signals at the...
New Risk • Jun 16New minor risk - Share price stabilityThe company's share price has been volatile over the past 3 months. It is more volatile than 75% of American stocks, typically moving 10% a week. This is considered a minor risk. Share price volatility indicates the stock is highly sensitive to market conditions or economic conditions rather than being sensitive to its own business performance, which may also be inconsistent. It also increases the risk of potential losses in the short term as the stock tends to have larger drops in price more frequently than other stocks. Currently, the following risks have been identified for the company: Minor Risks Currently unprofitable and not forecast to become profitable over next 3 years (US$48m net loss in 3 years). Share price has been volatile over the past 3 months (10% average weekly change). Shareholders have been diluted in the past year (2.2% increase in shares outstanding).
분석 기사 • Jun 07Calculating The Intrinsic Value Of Codexis, Inc. (NASDAQ:CDXS)Key Insights Codexis' estimated fair value is US$2.68 based on 2 Stage Free Cash Flow to Equity With US$2.63 share...
Price Target Changed • May 18Price target decreased by 7.1% to US$11.14Down from US$12.00, the current price target is an average from 7 analysts. New target price is 317% above last closing price of US$2.67. Stock is down 74% over the past year. The company is forecast to post a net loss per share of US$1.04 next year compared to a net loss per share of US$0.51 last year.
공시 • May 11Codexis, Inc. Unveils Eco Synthesis Platform for Large-Scale RNAi Therapeutics Production at Tides USACodexis, Inc. announced the unveiling of its Enzyme-Catalyzed Oligonucleotide (ECO) Synthesis(TM) technology, a proprietary new synthesis platform being developed for manufacturing RNA oligonucleotide therapeutics at scale. The ECO Synthesis(TM) technology was unveiled during a pre-conference workshop at the TIDES USA annual meeting, being held May 7-10, 2023, in San Diego, CA. Ribonucleic acid (RNA) as a therapeutic modality has gained tremendous traction in recent years with the growing number of messenger RNA (mRNA) vaccines and small interfering RNA (siRNA) product candidates advancing in clinical studies. However, large-scale production faces complex challenges in nucleic acids quality and quantity, as well as overall economics. By replacing phosphoramidite chemistry with enzymatic methods, Codexis' proprietary ECO Synthesis(TM)technology is specifically engineered to overcome these difficulties to enable scalable and sustainable manufacturing.
분석 기사 • May 09At US$3.41, Is It Time To Put Codexis, Inc. (NASDAQ:CDXS) On Your Watch List?Codexis, Inc. ( NASDAQ:CDXS ), is not the largest company out there, but it saw significant share price movement during...
Price Target Changed • May 08Price target decreased by 10% to US$11.57Down from US$12.88, the current price target is an average from 7 analysts. New target price is 239% above last closing price of US$3.41. Stock is down 66% over the past year. The company is forecast to post a net loss per share of US$0.96 next year compared to a net loss per share of US$0.51 last year.
