Madrigal Pharmaceuticals, Inc.

NasdaqGS:MDGL 株式レポート

時価総額：US$11.8b

Madrigal Pharmaceuticals 将来の成長

Future 基準チェック /66

Madrigal Pharmaceuticals利益と収益がそれぞれ年間59.1%と28.7%増加すると予測されています。EPS は年間 増加すると予想されています。自己資本利益率は 3 年後に61% 59.5%なると予測されています。

主要情報

59.1%

収益成長率

59.46%

EPS成長率

Biotechs 収益成長25.5%
収益成長率28.7%
将来の株主資本利益率61.05%
アナリストカバレッジ

Good

最終更新日13 May 2026

今後の成長に関する最新情報

Recent updates

ナラティブの更新 • May 18

MDGL: MASH Pool Assumptions Versus Gross To Net Execution Will Shape Outlook

The analyst price target for Madrigal Pharmaceuticals has risen from $529 to $550. Analysts point to survey work that highlights a large MASH treatment pool and higher projected Rezdiffra use, along with updated assumptions for patient mix, revenue growth, margins, and P/E multiples.
Seeking Alpha • Apr 28

Madrigal Pharmaceuticals: Boom Or Bust In MASH? Regretfully, I'm Bearish

Summary Madrigal Pharmaceuticals, Inc. receives a Sell rating, citing high valuation and intensifying MASH competition despite Rezdiffra's initial commercial success. Rezdiffra achieved $958.4m in 2025 sales with ~36,250 patients, but MDGL profitability remains elusive as operating expenses outpace revenue growth. SG&A and R&D costs are expected to rise in 2026, while no specific guidance has been provided, and consensus sees potential Q1 revenue softness. Pipeline bets and M&A speculation offer upside, but market congestion and uncertain long-term leadership prompt caution for MDGL stock after a 280% five-year gain. Read the full article on Seeking Alpha
ナラティブの更新 • Apr 27

MDGL: Gross To Net Execution And Margin Pressure Will Shape Balanced Outlook

Analysts have reset Madrigal Pharmaceuticals' price target to $529 from $570, reflecting updated forecasts that factor in recent commentary on gross to net adjustments, as well as revised assumptions for growth, profitability, and forward P/E. Analyst Commentary Bearish analysts have trimmed expectations for Madrigal Pharmaceuticals, pointing to updated assumptions around gross to net adjustments, as well as revisions to growth, profitability, and P/E assumptions.
ナラティブの更新 • Apr 13

MDGL: Gross To Net Execution And Cirrhosis Expansion Will Shape Balanced Outlook

Analyst price targets on Madrigal Pharmaceuticals have been reset to $529, with the change largely tied to updated forecasts that factor in comments on gross to net adjustments. Other recent research has introduced new bullish coverage and higher targets from different firms.
ナラティブの更新 • Mar 30

MDGL: MASH Combinations And Cirrhosis Expansion Will Shape Balanced Future Outlook

Analysts now set a consolidated price target for Madrigal Pharmaceuticals at $529, down from previous levels such as $570, reflecting updated forecasts around gross-to-net adjustments, even as model assumptions for revenue growth, profit margins, and future P/E remain broadly consistent. Analyst Commentary Recent research updates on Madrigal Pharmaceuticals show a mix of support and caution, with several bearish analysts rethinking how much upside is left after the stock's strong prior move and the latest company updates.
ナラティブの更新 • Mar 16

MDGL: Cirrhosis Expansion And MASH Combinations Will Drive Future Repricing

Analysts now set the fair value estimate for Madrigal Pharmaceuticals at $529, up $27 from $502. This reflects updated models that factor in gross to net adjustments, recent licensing activity, and mixed revisions to Street price targets across firms.
ナラティブの更新 • Mar 02

MDGL: MASH Franchise And DGAT2 Combo Plans Will Drive Future Upside

Madrigal Pharmaceuticals' updated analyst price target reflects a modest adjustment, with fair value edging from about $900.66 to $904.36 as analysts factor in recent target cuts around $529 to $570, alongside fresh bullish initiation and higher targets above $600 tied to updated product and combination-therapy assumptions. Analyst Commentary Recent Street research on Madrigal Pharmaceuticals shows a mix of caution and optimism, with valuation debate sitting alongside higher fair value estimates tied to execution on its MASH franchise and new pipeline additions.
ナラティブの更新 • Feb 16

MDGL: Future Leadership Will Rely On MASH Cirrhosis Uptake Versus GLP 1 Pressure

The analyst price target for Madrigal Pharmaceuticals has been revised higher to $671.07, up from $603.47. Analysts now factor in updated assumptions for fair value, discount rate, revenue growth, profit margins, and future P/E, following recent research that highlights both enthusiasm for Rezdiffra's commercial potential and some valuation concerns.
ナラティブの更新 • Feb 02

MDGL: MASH Franchise Expansion And New DGAT2 Combo Study Will Drive Upside

The updated analyst price target for Madrigal Pharmaceuticals moves from about $567 to roughly $901 per share, with analysts pointing to stronger modeled profitability, a higher assumed future P/E multiple, and continued enthusiasm for Rezdiffra across multiple research updates. Analyst Commentary Recent research coverage on Madrigal Pharmaceuticals has leaned positive overall, with a series of price target increases and a few ratings changes that highlight how divided views are at current levels.
ナラティブの更新 • Jan 19

MDGL: Cirrhosis Expansion And Combination Plans Will Test High Expectations

Analysts have modestly adjusted their price targets for Madrigal Pharmaceuticals, with a slight upward shift reflected in updated models that factor in Rezdiffra uptake, expanded MASH opportunities including potential combinations with ervogastat, and a range of views on valuation and longer term penetration assumptions. Analyst Commentary Recent research on Madrigal Pharmaceuticals shows a mix of optimism around Rezdiffra and its potential role in MASH, paired with increasingly careful debate around valuation, competitive pressures, and execution risks.
ナラティブの更新 • Jan 04

MDGL: Elevated Expectations For Cirrhosis Opportunity Will Face Heightened Competitive Pressures

Madrigal Pharmaceuticals' analyst price target has risen sharply from approximately $312 to $502 per share, as analysts factor in stronger long term profitability and higher penetration assumptions for Rezdiffra across F2-F3 and F4c MASH populations, despite moderating top line growth expectations and a modestly higher discount rate. Analyst Commentary Recent Street research reflects a broadly constructive outlook on Madrigal Pharmaceuticals, with multiple firms lifting price targets in response to stronger than expected Rezdiffra uptake and expanding commercial visibility in both F2 F3 and compensated F4c MASH populations.
ナラティブの更新 • Dec 20

MDGL: Future Leadership Will Depend On Cirrhosis Uptake Amid GLP 1 Competition

The analyst price target for Madrigal Pharmaceuticals has been raised by approximately $40 per share, as analysts cite stronger-than-expected real-world uptake of Rezdiffra, expanded penetration assumptions across F2, F3, and emerging F4c populations, and increased confidence in the drug's long-term commercial trajectory despite GLP-1 competition. Analyst Commentary Recent Street research reflects a strongly constructive tone on Madrigal Pharmaceuticals, with multiple firms lifting price targets into the mid to high $500s and $600s range, underpinned by faster than expected Rezdiffra adoption and expanding addressable populations across F2, F3, and emerging F4c disease.
ナラティブの更新 • Dec 06

MDGL: Future Leadership Will Depend On Expanding MASH Cirrhosis And Fibrosis Therapy Adoption

Madrigal Pharmaceuticals' analyst price target has been raised into the low to mid $600s per share from the high $500s, as analysts factor in stronger long term profitability expectations and sustained Rezdiffra uptake across F2-F3 and emerging F4c populations. Analyst Commentary Bullish analysts are increasingly constructive on Madrigal's outlook as they update models to reflect stronger real world Rezdiffra uptake, expanded addressable populations and emerging combination therapy optionality.
ナラティブの更新 • Nov 21

MDGL: Future Leadership Will Depend On Expanding Liver Fibrosis Therapy Penetration Amid Competition

Madrigal Pharmaceuticals’ analyst price target has been raised from approximately $536 to $564 per share. This reflects increased confidence among analysts in Rezdiffra’s market penetration and longer-term growth prospects, despite evolving competitive dynamics.
分析記事 • Nov 12

Madrigal Pharmaceuticals, Inc.'s (NASDAQ:MDGL) 26% Price Boost Is Out Of Tune With Revenues

Madrigal Pharmaceuticals, Inc. ( NASDAQ:MDGL ) shares have continued their recent momentum with a 26% gain in the last...
ナラティブの更新 • Nov 07

MDGL: Future Revenue Leadership Will Depend On Therapy Adoption Amid Rising Competition

The analyst consensus price target for Madrigal Pharmaceuticals has increased by approximately $23 to $536, as analysts cite continued strength from Rezdiffra as well as improved long-term profitability expectations. Analyst Commentary Bullish Takeaways Bullish analysts have increased price targets for Madrigal Pharmaceuticals, emphasizing Rezdiffra’s ongoing outperformance and supportive market dynamics, even as new competitors enter the F2-F3 MASH segment.
ナラティブの更新 • Oct 24

EU Expansion and Combination Therapies Will Drive Future Opportunity

Analysts have increased their price target for Madrigal Pharmaceuticals by approximately $100. They now expect shares to reach around $550, citing Rezdiffra's robust launch progress, new approvals, and potential from combination therapy strategies.
ナラティブの更新 • Oct 10

US Patent And EU Expansion Will Secure Future Potential

The analyst price target for Madrigal Pharmaceuticals has increased by approximately $8 to $489.54. Analysts cite stronger-than-expected revenue growth, improved profit margins, and favorable momentum following recent approvals and positive market dynamics.
ナラティブの更新 • Sep 26

US Patent And EU Expansion Will Secure Future Potential

Analysts raised Madrigal Pharmaceuticals’ price target to $481.85, citing strong EU approval momentum, first-mover advantage for Rezdiffra in MASH, guideline inclusion, and extended patent protection driving long-term value. Analyst Commentary Bullish analysts cite Madrigal’s strong positioning to dominate the metabolic dysfunction-associated steatohepatitis (MASH) treatment landscape through its proprietary thyroid hormone receptor-beta platform.
ナラティブの更新 • Sep 11

US Patent And EU Expansion Will Secure Future Potential

Madrigal Pharmaceuticals’ consensus price target has been raised to $466.38 as analysts cite EU conditional approval, first-line therapy status, improved sales visibility, and extended patent protection for Rezdiffra as key drivers strengthening blockbuster potential and reducing risk. Analyst Commentary Bullish analysts believe Madrigal is uniquely positioned to dominate the metabolic dysfunction-associated steatohepatitis (MASH) market, leveraging its thyroid hormone receptor-beta platform.
ナラティブの更新 • Aug 27

US Patent And EU Expansion Will Secure Future Potential

The consensus analyst price target for Madrigal Pharmaceuticals was raised from $449.57 to $461.43, primarily driven by the EU approval and expanded patent protection for Rezdiffra, which de-risks future cash flows and supports robust sales expectations in a large addressable market. Analyst Commentary Bullish analysts updated their models to reflect the recent EU approval of Rezdiffra, reducing risk and subsequently lowering the discount rate applied to future cash flows.
分析記事 • Aug 22

Madrigal Pharmaceuticals, Inc.'s (NASDAQ:MDGL) 30% Price Boost Is Out Of Tune With Revenues

Despite an already strong run, Madrigal Pharmaceuticals, Inc. ( NASDAQ:MDGL ) shares have been powering on, with a gain...
分析記事 • Aug 13

Forecast: Analysts Think Madrigal Pharmaceuticals, Inc.'s (NASDAQ:MDGL) Business Prospects Have Improved Drastically

NasdaqGS:MDGL 1 Year Share Price vs Fair Value Explore Madrigal Pharmaceuticals's Fair Values from the Community and...
分析記事 • Aug 08

Earnings Beat: Madrigal Pharmaceuticals, Inc. (NASDAQ:MDGL) Just Beat Analyst Forecasts, And Analysts Have Been Lifting Their Forecasts

NasdaqGS:MDGL 1 Year Share Price vs Fair Value Explore Madrigal Pharmaceuticals's Fair Values from the Community and...
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新しいナラティブ • May 03

FDA Approval Will Expand MASH Treatment Market Reach

First FDA-approved MASH treatment and strong U.S. market launch position Madrigal Pharmaceuticals for significant revenue growth.
Seeking Alpha • Feb 26

Madrigal Pharmaceuticals Q4 Earnings Review: Strong Quarter, Even Stronger Outlook

Summary Madrigal Pharmaceuticals, Inc.'s Rezdiffra, the first approved drug for MASH, showed strong sales growth, with Q4 net sales up 66% to $103.3m. Despite a net loss of $466m in 2024, Madrigal's cash position improved to $931m, and Rezdiffra's market potential remains significant with no current competitors. Positive study data and upcoming European approval could further boost Rezdiffra's market presence, making Madrigal a prime M&A target. While GLP-1 agonists pose a potential threat, Rezdiffra's oral availability and strong initial market penetration suggest long-term growth and a solid buy opportunity for MDGL stock. Read the full article on Seeking Alpha
Seeking Alpha • Jan 19

Madrigal Pharmaceuticals Rezdiffra Vies For Blockbuster Status In MASH

Summary Madrigal Pharma's REZDIFFRA achieved $100-$103M in Q4 sales, marking 61% growth, with market penetration of only 4% relative to TAM, indicating blockbuster potential. Potential competition from GLP-1 drugs and other MASH therapies exists, but REZDIFFRA's combination use and first-mover advantage mitigate these risks. Analysts project $515M in 2025 sales, driven by Medicare coverage, low market penetration, and European launch, making MDGL stock a STRONG BUY. Despite volatility and buyout speculation, Madrigal's commanding position in MASH supports a 12-month price target of $455/share. Read the full article on Seeking Alpha
Seeking Alpha • Jan 09

Fast Drug Launch For Madrigal Pharmaceuticals Brings Buyout Discussion

Summary Rezdiffra's strong launch has been confirmed by robust sales in the first two quarters, even though it may have only been used in 2% of its current target patient population. Competitors with MASH therapies like NVO, SGMT, ALT and Boehringer Ingelheim are making progress, although the possibility of combinations could limit any downside for MDGL. There is ongoing discussion about a potential buyout, adding another layer of interest for investors, and a potential EU launch in H2'25. Read the full article on Seeking Alpha
Seeking Alpha • Nov 03

Rezdiffra Gains Traction In NASH As Madrigal Pharmaceuticals Targets European Expansion

Summary Madrigal Pharmaceuticals' Rezdiffra has favorable initial market adoption and FDA approval, positioning it as a foundational therapy for NASH with advanced fibrosis. Broad insurance coverage and allowance for non-invasive testing [NIT] enhance patient accessibility and Rezdiffra’s adoption rate. Competition from Novo Nordisk's Semaglutide poses a market risk, but Rezdiffra’s liver-specific mechanism offers a targeted advantage. MDGL's strategic geographic expansion, particularly EMA approval in Europe, could significantly increase Rezdiffra’s TAM. Despite its cash burn, MDGL's growth and cash reserves provide enough runway. Thus, I maintain my "Buy" rating for MDGL stock. Read the full article on Seeking Alpha
Seeking Alpha • Oct 24

Madrigal: Why I'm Having Doubts On The Bull Case Ahead Of Q3 Earnings

Summary Madrigal's Rezdiffra, the first FDA-approved drug for MASH, shows promise but faces competition from GLP-1 drugs and financial challenges in launching in Europe. Despite meeting Phase 3 endpoints and early sales success, Madrigal's Q3 earnings will be crucial in determining Rezdiffra's commercial viability and stock performance. The potential for Rezdiffra to achieve blockbuster status is tempered by its high cost and the emerging threat of GLP-1 agonists in the MASH market. Given the uncertainties and competitive landscape, I am downgrading Madrigal from a "Buy" to a "Hold" ahead of Q3 earnings. Read the full article on Seeking Alpha
Seeking Alpha • Aug 08

While Madrigal's Rezdiffra Impresses, Great Uncertainties Loom In MASH Market

Summary Madrigal Pharmaceuticals' Q2 2024 revenue from Rezdiffra exceeded expectations at $14.6 million. The company's SG&A expenses surged to $105.4 million, reflecting launch activities. Over 2,000 patients are currently on Rezdiffra, with broad insurance coverage. I recommend selling Madrigal Pharmaceuticals due to significant uncertainties and competitive pressures. Read the full article on Seeking Alpha
Seeking Alpha • Jun 09

Madrigal May Not Be Able To Shrug GLP-1 Drugs For Long

Summary Eli Lilly's tirzepatide shows potential in resolving metabolic dysfunction-associated steatohepatitis without worsening fibrosis. GLP-1 drugs pose a serious threat to Madrigal's Rezdiffra, potentially dominating the MASH market. Madrigal's financial health is stable with sufficient funding for the launch of Rezdiffra, but profitability and market prospects remain uncertain. Despite its market position, Madrigal faces substantial risks, leading to a sell recommendation. Read the full article on Seeking Alpha

業績と収益の成長予測

NasdaqGS:MDGL - アナリストの将来予測と過去の財務データ ( )USD Millions
日付収益収益フリー・キャッシュフロー営業活動によるキャッシュ平均アナリスト数
12/31/20282,99979171058911
12/31/20272,20831322018315
12/31/20261,496-197-218-13015
3/31/20261,132-309-275-268N/A
12/31/2025958-288-193-190N/A
9/30/2025741-289-165-161N/A
6/30/2025516-282-308-307N/A
3/31/2025317-392-401-395N/A
12/31/2024180-466-462-456N/A
9/30/202477-519-438-431N/A
6/30/202415-510-456-449N/A
3/31/2024N/A-444-391-389N/A
12/31/2023N/A-374-326-324N/A
9/30/2023N/A-347-303-303N/A
6/30/2023N/A-330-277-277N/A
3/31/2023N/A-315-259-259N/A
12/31/2022N/A-295-225-225N/A
9/30/2022N/A-274-215-214N/A
6/30/2022N/A-256-201-201N/A
3/31/2022N/A-247-191-190N/A
12/31/2021N/A-242-184-184N/A
9/30/2021N/A-236-191-191N/A
6/30/2021N/A-231-193-193N/A
3/31/2021N/A-219-171-170N/A
12/31/2020N/A-202-158-158N/A
9/30/2020N/A-171-115-115N/A
6/30/2020N/A-134-79-78N/A
3/31/2020N/A-105-66-66N/A
12/31/2019N/A-84N/A-42N/A
9/30/2019N/A-68N/A-36N/A
6/30/2019N/A-55N/A-30N/A
3/31/2019N/A-42N/A-23N/A
12/31/2018N/A-33N/A-26N/A
9/30/2018N/A-30N/A-25N/A
6/30/2018N/A-30N/A-25N/A
3/31/2018N/A-32N/A-27N/A
12/31/2017N/A-31N/A-22N/A
9/30/2017N/A-30N/A-22N/A
6/30/2017N/A-36N/A-26N/A
3/31/2017N/A-31N/A-21N/A
12/31/2016N/A-26N/A-18N/A
9/30/2016N/A-21N/A-13N/A
6/30/2016N/A-8N/A-5N/A
3/31/2016N/A-7N/A-3N/A

アナリストによる今後の成長予測

収入対貯蓄率: MDGLは今後 3 年間で収益性が向上すると予測されており、これは 貯蓄率 ( 3.5% ) よりも高い成長率であると考えられます。

収益対市場: MDGL今後 3 年間で収益性が向上すると予想されており、これは市場平均を上回る成長と考えられます。

高成長収益: MDGL今後 3 年以内に収益を上げることが予想されます。

収益対市場: MDGLの収益 ( 28.7% ) US市場 ( 11.6% ) よりも速いペースで成長すると予測されています。

高い収益成長: MDGLの収益 ( 28.7% ) 20%よりも速いペースで成長すると予測されています。

一株当たり利益成長率予想

将来の株主資本利益率

将来のROE: MDGLの 自己資本利益率 は、3年後には非常に高くなると予測されています ( 61 %)。

成長企業の発掘

7D

1Y

7D

1Y

7D

1Y

企業分析と財務データの現状

データ最終更新日（UTC時間）
企業分析2026/05/20 09:49
終値2026/05/20 00:00
収益2026/03/31
年間収益2025/12/31

データソース

企業分析に使用したデータはS&P Global Market Intelligence LLC のものです。本レポートを作成するための分析モデルでは、以下のデータを使用しています。データは正規化されているため、ソースが利用可能になるまでに時間がかかる場合があります。

パッケージデータタイムフレーム米国ソース例
会社財務10年
  • 損益計算書
  • キャッシュ・フロー計算書
  • 貸借対照表
アナリストのコンセンサス予想+プラス3年
  • 予想財務
  • アナリストの目標株価
市場価格30年
  • 株価
  • 配当、分割、措置
所有権10年
  • トップ株主
  • インサイダー取引
マネジメント10年
  • リーダーシップ・チーム
  • 取締役会
主な進展10年
  • 会社からのお知らせ

* 米国証券を対象とした例であり、非米国証券については、同等の規制書式および情報源を使用。

特に断りのない限り、すべての財務データは1年ごとの期間に基づいていますが、四半期ごとに更新されます。これは、TTM（Trailing Twelve Month）またはLTM（Last Twelve Month）データとして知られています。詳細はこちら。

分析モデルとスノーフレーク

本レポートを生成するために使用した分析モデルの詳細は当社のGithubページでご覧いただけます。また、レポートの使用方法に関するガイドやYoutubeのチュートリアルも掲載しています。

シンプリー・ウォールストリート分析モデルを設計・構築した世界トップクラスのチームについてご紹介します。

業界およびセクターの指標

私たちの業界とセクションの指標は、Simply Wall Stによって6時間ごとに計算されます。

アナリスト筋

Madrigal Pharmaceuticals, Inc. 15 これらのアナリストのうち、弊社レポートのインプットとして使用した売上高または利益の予想を提出したのは、 。アナリストの投稿は一日中更新されます。28

アナリスト機関
Eliana MerleBarclays
Matthew LuchiniBMO Capital Markets Equity Research
Jason ZemanskyBofA Global Research