Xenon Pharmaceuticals Inc.

Report azionario NasdaqGM:XENE

Capitalizzazione di mercato: US$5.2b

Xenon Pharmaceuticals Gestione

Criteri Gestione verificati 4/4

Xenon Pharmaceuticals Il CEO è Ian Mortimer, nominato in Mar2018, e ha un mandato di 8.17 anni. la retribuzione annua totale è $ 9.22M, composta da 8.5% di stipendio e 91.5% di bonus, comprese azioni e opzioni aziendali. possiede direttamente 0.035% delle azioni della società, per un valore di $ 1.85M. La durata media del mandato del team dirigenziale e del consiglio di amministrazione è rispettivamente 4.1 anni e 5.2 anni.

Informazioni chiave

Ian Mortimer

Amministratore delegato

US$9.2m

Compenso totale

Percentuale dello stipendio del CEO8.52%
Mandato del CEO8.2yrs
Proprietà del CEO0.04%
Durata media del management4.1yrs
Durata media del Consiglio di amministrazione5.2yrs

Aggiornamenti recenti sulla gestione

Recent updates

Seeking Alpha Apr 22

Xenon's Phase 3 Supports A 'Buy' Despite Its Premium

Summary Xenon Pharmaceuticals Inc.’s bull case improved after X-TOLE2 showed robust focal seizure reduction in a highly refractory patient population. Azetukalner’s differentiated Kv7 mechanism, once-daily dosing, and no-titration profile may help its future adoption, especially for polytreated epilepsy patients. XENE plans its NDA submission in Q3 2026, which would be a key transition toward potential commercialization and revenues. XENE also has ample liquidity after recent equity raises, which I think materially reduces its risk despite the ongoing cash burn. I believe XENE stock’s valuation already reflects its success to some extent. So, further upside likely depends on new indications and commercial execution. Read the full article on Seeking Alpha
Nuova narrazione Mar 27

Epilepsy And Depression Pipeline Will Define Fair Long Term Outlook

Catalysts About Xenon Pharmaceuticals Xenon Pharmaceuticals is a neuroscience focused biopharma company developing ion channel based therapies for epilepsy, depression, bipolar disorder and pain. What are the underlying business or industry changes driving this perspective?
Nuova narrazione Mar 09

Late Stage Neuroscience Pipeline Will Transform Ion Channel Franchise Over The Coming Years

Catalysts About Xenon Pharmaceuticals Xenon Pharmaceuticals is a neuroscience focused biopharma company developing ion channel targeted medicines for epilepsy, neuropsychiatric conditions and pain. What are the underlying business or industry changes driving this perspective?
Articolo di analisi Oct 01

Xenon Pharmaceuticals (NASDAQ:XENE) Is In A Good Position To Deliver On Growth Plans

There's no doubt that money can be made by owning shares of unprofitable businesses. For example, although Amazon.com...
Seeking Alpha Apr 18

Xenon- A Later Stage Story

Summary Xenon's lead asset, azetukalner, shows promise in treating focal onset seizures with positive phase IIb results and upcoming phase III data expected by end of 2025. Azetukalner's unique Kv7 potassium channel mechanism and rapid onset of action could address unmet needs in treatment-resistant epilepsy and potentially depression. Financially stable, Xenon is well-funded into 2027, with potential $1Bn market opportunity if azetukalner succeeds in focal onset seizures and expands into other indications. Despite broader biotech market challenges, Xenon's strong efficacy and safety data position it well, with significant interest from major pharma in neurology and neuropsychiatry. Read the full article on Seeking Alpha
Seeking Alpha Jan 16

Xenon Pharmaceuticals: 2025 Could Be Pivotal For Azetukalner's Epilepsy Potential

Summary Xenon Pharmaceuticals' Azetukalner has good Phase 2 data for MDD using Kv7 potassium channels. This also gives it a good safety profile. The company has robust financials with a runway that should last into 2027 or more. So, I think it should have enough resources to take its late-stage pipeline to approval. Epilepsy and MDD have an attractive TAM of several billions of dollars in the US and abroad. XENE could tap into these niche markets over time. I also believe its late-stage IP is diversified with ion channel modulators for pain and other neurological conditions. So it’s not overly exposed to Azetukalner. I concede that XENE has a premium valuation, but I think 2025 will provide significant clinical data that could justify a “Buy” rating at these levels. Read the full article on Seeking Alpha
Seeking Alpha Aug 09

Xenon Pharmaceuticals: Good Data In Epilepsy, But Doubts Remain

Summary Xenon Pharmaceuticals is a Canadian biopharma company targeting neurological diseases with a focus on ion channel-blocking technology. The clinical stage asset, azetukalner, is in late stage development for epilepsy and Major Depressive Disorder, showing promising results in reducing seizure frequency. Despite a history of failures and low trading volume, Xenon has a strong cash position and upcoming catalysts in phase 3 trials for their lead asset. Read the full article on Seeking Alpha
Seeking Alpha Feb 08

Xenon Pharmaceuticals: Analysts Still Positive Despite Recent Trial 'Setbacks'

Summary Today, we focused on Xenon Pharmaceuticals Inc., a clinical-stage biopharmaceutical company focused on developing therapeutics for neurological disorders. The company has experienced "setbacks" in recent trials, but its primary drug candidate, XEN1101, shows significant potential for treating epilepsy. Xenon has initiated Phase 3 clinical trials for XEN1101 and has received myriad positive ratings from analysts, but the stock may be vulnerable to profit-taking. An analysis around Xenon Pharmaceuticals follows in the paragraphs below. Read the full article on Seeking Alpha
Seeking Alpha Oct 19

Xenon started at outperform at Raymond James on experimental epilepsy drug

Raymond James has initiated Xenon Pharmaceuticals (NASDAQ:XENE) with an outperform rating citing the blockbuster potential of XEN1101, currently in phase 2 for epilepsy. The firm has a $52 price target (~46% upside based on Tuesday's close). Analyst Danielle Brill is confident that XEN1101 will be successful given its strong phase 2 results. She predicted a greater than $1B peak sales opportunity. Xenon (XENE) plans to initiate two identical phase 3 clinical trials. She noted that the the candidate, which is also under development for major depressive disorder, could further benefit from proof-of-concept data in that indication expected in 2023. Brill added that the company's pipeline also presents growth opportunities with XEN496 in KCNQ2 developmental and epileptic encephalopathy (KCNQ2-DEE), and NBI-921352 for SCN8A developmental and epileptic encephalopathy (SCN8A-DEE). XEN1101 is also under investigation for primary generic clonic tonic seizures (PGTCS). In August, BofA started Xenon (XENE) with a buy rating also citing the blockbuster potential of XEN1101 for epilepsy.
Seeking Alpha Sep 06

Putting Xenon Pharmaceuticals Back In The Spotlight

Summary Today, we are revisiting Xenon Pharmaceuticals for the first time in 2022. The company is well-funded and advancing several compounds in its pipeline, one of which might have blockbuster potential. An investment analysis follows in the paragraphs below. "Potential has a shelf life." - Margaret Atwood We last looked in on Xenon Pharmaceuticals (XENE) nearly nine months ago. In the summary of that article, the conclusion was that the company had some promising attributes and was worthy of a small 'watch item' via covered call positions. That turned out to be a profitable trade. Time for another potential round trip? We update the investment thesis on Xenon below. Seeking Alpha Company Overview: Xenon Pharmaceuticals is a clinical-stage biotech company focused on developing therapeutics to treat patients with neurological disorders. The company is based just outside of Vancouver, Canada. The stock trades just under $40.00 a share and sports an approximate market cap just north of $2.4 billion. August Company Presentation The company has several compounds in development as can be seen by the pipeline chart above. August Company Presentation The most important asset in development is a candidate called for the moment XEN1011. This is a next generation Kv7 potassium channel opener with potential applications in treating the focal onset seizures which occurs in epileptics as well as other potential neurological disorders. August Company Presentation A Phase 2b trial produced encouraging results in the fourth quarter of last year. The company then disclosed new, compelling efficacy data from that study 'X-TOLE' in June of this year. A Phase 2 study 'X-TOLE2' should initiate by the end of this year, followed shortly by a Phase 3 trial X-TOLE3. If successful, the company plans to submit a market application around this compound to treat epilepsy. August Company Presentation The compound is also in development for other neurological disorders. The company currently has a Phase 2 'X-NOVA' study underway examining XEN1101 in major depressive disorder or MDD. This trial in parallel with an investigator-led Phase 2 MDD study led by Xenon's collaborators at Mount Sinai. Topline results should be out in 2023. August Company Presentation XEN1101 is also now targeting primary generalized tonic clonic seizures or PGTCS. Management plans to initiate a Phase 3 clinical trial, called X-ACKT, to support potential regulatory submissions in PGTCS. This study should kick soon after initiation of the X-TOLE2 trial. August Company Presentation Another compound 'XEN496' is being developed to treat rare KCNQ2-DEE pediatric epilepsy. A Phase 3 study called EPIK, is ongoing to evaluate the efficacy, safety, and tolerability of XEN496 administered as adjunctive treatment in approximately 40 pediatric patients aged one month to less than six years with KCNQ2-DEE. This trial should complete sometime in 2023. August Company Presentation Finally the company has licensed a selective Nav1.6 sodium channel inhibitor 'XEN901', now known as NBI-921352, to Neurocrine Biosciences (NBIX). That compound is in Phase 2 development for a couple of indications. As the result of this licensing agreement, Xenon has the potential to receive certain clinical, regulatory, and commercial milestone payments, as well as future sales royalties on any eventual commercialization. Analyst Commentary & Balance Sheet: Since second quarter results were posted on August 9th, five analyst firms including Needham and Wedbush have reissued Buy ratings on XENE. Price targets proffered ranged from $46 to $52 a share. On August 29th, Bank of America initiated the shares as a new Buy with a $45 a share price target. Here is the commentary from the bank's analyst at the time of that call.
Seeking Alpha Aug 29

Xenon initiated with Buy at BofA citing potential of anti-seizure drug

Bank of America launched its coverage on clinical-stage biotech Xenon Pharmaceuticals Inc. (NASDAQ:XENE) with a Buy rating on Monday, arguing that the company’s mid-stage epilepsy candidate XEN1101 is poised to become a blockbuster drug. XEN1101 belongs to a class of drugs known as Kv7 potassium channel openers, and the drug is expected to undergo its Phase 3 program in H2 2022, XENE said this month.   The analysts led by Jason M. Gerberry point to the blockbuster potential of XEN1101 ahead of important catalysts for its safety data, second confirmatory, and label expansion studies. The ease of use, novel mechanism of action, and strong efficacy differentiate XEN1101 from other anti-seizure medications, the team with a $48 per share target on XENE argued. Wall Street stands firmly behind the prospects of Xenon (XENE) with eleven Buy ratings and no Hold or Sell ratings.
Seeking Alpha Dec 13

Sizing Up Xenon Pharmaceuticals

Today, we look at Xenon Pharmaceuticals, a clinical-stage biotech concern with several products advancing in its pipeline. The stock recently has surged on top of positive mid-stage trial results. The shares have also seen some insider buying lately as well. A full investment analysis follows in the paragraphs below.

Analisi delle retribuzioni degli amministratori delegati

Come è cambiata la remunerazione di Ian Mortimer rispetto agli utili di Xenon Pharmaceuticals?
DataCompenso totaleStipendioUtili della società
Mar 31 2026n/an/a

-US$383m

Dec 31 2025US$9mUS$786k

-US$346m

Sep 30 2025n/an/a

-US$306m

Jun 30 2025n/an/a

-US$278m

Mar 31 2025n/an/a

-US$251m

Dec 31 2024US$10mUS$715k

-US$234m

Sep 30 2024n/an/a

-US$213m

Jun 30 2024n/an/a

-US$199m

Mar 31 2024n/an/a

-US$189m

Dec 31 2023US$10mUS$666k

-US$182m

Sep 30 2023n/an/a

-US$175m

Jun 30 2023n/an/a

-US$164m

Mar 31 2023n/an/a

-US$147m

Dec 31 2022US$9mUS$595k

-US$125m

Sep 30 2022n/an/a

-US$113m

Jun 30 2022n/an/a

-US$91m

Mar 31 2022n/an/a

-US$83m

Dec 31 2021US$4mUS$524k

-US$77m

Sep 30 2021n/an/a

-US$66m

Jun 30 2021n/an/a

-US$59m

Mar 31 2021n/an/a

-US$37m

Dec 31 2020US$2mUS$462k

-US$29m

Sep 30 2020n/an/a

-US$28m

Jun 30 2020n/an/a

-US$28m

Mar 31 2020n/an/a

-US$38m

Dec 31 2019US$2mUS$421k

-US$42m

Compensazione vs Mercato: La retribuzione totale di Ian ($USD 9.22M ) è circa la media per le aziende di dimensioni simili nel mercato US ($USD 8.38M ).

Compensazione vs guadagni: La retribuzione di Ian è stata coerente con le performance aziendali dell'ultimo anno.


AMMINISTRATORE DELEGATO

Ian Mortimer (49 yo)

8.2yrs
Mandato
US$9,221,712
Compensazione

Mr. Ian C. Mortimer, M.B.A, C.P.A, C.M.A., has been the Chief Executive Officer and Director at Xenon Pharmaceuticals Inc. since June 03, 2021 and was its Interim CFO & Principal Financial Officer since Ju...


Gruppo dirigente

NomePosizioneMandatoCompensazioneProprietà
Ian Mortimer
President8.2yrsUS$9.22m0.035%
$ 1.9m
Thomas Kelly
Chief Financial Officerless than a yearUS$7.58mNessun dato
Andrea DiFabio
Chief Legal Officer & Corporate Secretary3.5yrsUS$3.06m0.0076%
$ 395.3k
Christopher Kenney
Chief Medical Officer4.8yrsUS$3.15m0.0073%
$ 382.8k
Darren Cline
Chief Commercial Officerless than a yearUS$4.25mNessun dato
Matthew Ronsheim
Chief Operating Officer1.8yrsNessun datoNessun dato
Shelley McCloskey
Executive Vice President of Human Resources6.7yrsNessun datoNessun dato
Robin Sherrington
Executive Vice President of Strategy & Innovationno dataUS$2.37mNessun dato
James Empfield
Executive Vice President of Drug Discovery10.3yrsUS$545.00kNessun dato
Colleen Alabiso
Senior Vice President of Corporate Affairsno dataNessun datoNessun dato
J.P. Gilbert
Senior Directorno dataNessun datoNessun dato
4.1yrs
Durata media
57yo
Età media

Gestione esperta: Il team dirigenziale di XENE è considerato esperto (durata media dell'incarico 4.1 anni).


Membri del Consiglio di amministrazione

NomePosizioneMandatoCompensazioneProprietà
Ian Mortimer
President4.9yrsUS$9.22m0.035%
$ 1.9m
Justin Gover
Independent Director2.8yrsUS$478.92k0%
$ 0
Gary Patou
Independent Director22.3yrsUS$461.42k0.029%
$ 1.5m
C. Machado
Independent Director5.5yrsUS$471.42k0%
$ 0
Steven Gannon
Independent Director11yrsUS$473.92k0.011%
$ 576.5k
Dawn Svoronos
Independent Chairman9.7yrsUS$498.92k0.026%
$ 1.4m
Gillian Cannon
Independent Director2.8yrsUS$458.92k0%
$ 0
Elizabeth Garofalo
Independent Director4.9yrsUS$458.92k0%
$ 0
5.2yrs
Durata media
62.5yo
Età media

Consiglio di amministrazione esperto: I membri del consiglio di amministrazione di XENE sono considerati esperti (durata media dell'incarico 5.2 anni).


Analisi aziendale e situazione dei dati finanziari

DatiUltimo aggiornamento (ora UTC)
Analisi dell'azienda2026/05/25 14:18
Prezzo dell'azione a fine giornata2026/05/22 00:00
Utili2026/03/31
Utili annuali2025/12/31

Fonti dei dati

I dati utilizzati nella nostra analisi aziendale provengono da S&P Global Market Intelligence LLC. I seguenti dati sono utilizzati nel nostro modello di analisi per generare questo report. I dati sono normalizzati, il che può comportare un ritardo nella disponibilità della fonte.

PacchettoDatiTempisticaEsempio Fonte USA *
Dati finanziari della società10 anni
  • Conto economico
  • Rendiconto finanziario
  • Bilancio
Stime di consenso degli analisti+3 anni
  • Previsioni finanziarie
  • Obiettivi di prezzo degli analisti
Prezzi di mercato30 anni
  • Prezzi delle azioni
  • Dividendi, scissioni e azioni
Proprietà10 anni
  • Top azionisti
  • Insider trading
Gestione10 anni
  • Team di leadership
  • Consiglio di amministrazione
Sviluppi principali10 anni
  • Annunci aziendali

* Esempio per i titoli statunitensi, per i titoli non statunitensi si utilizzano forme e fonti normative equivalenti.

Se non specificato, tutti i dati finanziari si basano su un periodo annuale ma vengono aggiornati trimestralmente. Si tratta dei cosiddetti dati TTM (Trailing Twelve Month) o LTM (Last Twelve Month). Per saperne di più.

Modello di analisi e Snowflake

I dettagli del modello di analisi utilizzato per generare questo report sono disponibili sulla nostra pagina Github; abbiamo anche guide su come utilizzare i nostri report e tutorial su Youtube.

Scoprite il team di livello mondiale che ha progettato e realizzato il modello di analisi Simply Wall St.

Metriche di settore e industriali

Le nostre metriche di settore e di sezione sono calcolate ogni 6 ore da Simply Wall St; i dettagli del nostro processo sono disponibili su Github.

Fonti analitiche

Xenon Pharmaceuticals Inc. è coperta da 25 analisti. 17 di questi analisti ha fornito le stime di fatturato o di utile utilizzate come input per il nostro report. Le stime degli analisti vengono aggiornate nel corso della giornata.

AnalistaIstituzione
Brian SkorneyBaird
Jason Matthew GerberryBofA Global Research
John NewmanCanaccord Genuity