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Taysha Gene Therapies, Inc.NasdaqGS:TSHA Stock Report

Market Cap US$782.9m
Share Price
US$3.00
My Fair Value
US$8.67
65.4% undervalued intrinsic discount
1Y36.4%
7D2.0%
Portfolio Value
View

Taysha Gene Therapies, Inc.

NasdaqGS:TSHA Stock Report

Market Cap: US$782.9m

Taysha Gene Therapies (TSHA) Stock Overview

A clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. More details

TSHA fundamental analysis
Snowflake Score
Valuation3/6
Future Growth2/6
Past Performance0/6
Financial Health4/6
Dividends0/6

TSHA Community Fair Values

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US$8.32
FV
63.9% undervalued intrinsic discount
123.23%
Revenue growth p.a.
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10users have followed this narrative
24 days ago author updated this narrative

Taysha Gene Therapies, Inc. Competitors

Price History & Performance

Summary of share price highs, lows and changes for Taysha Gene Therapies
Historical stock prices
Current Share PriceUS$3.00
52 Week HighUS$3.31
52 Week LowUS$1.05
Beta0.96
1 Month Change11.52%
3 Month Change9.09%
1 Year Change36.36%
3 Year Change-8.54%
5 Year Changen/a
Change since IPO-87.53%

Recent News & Updates

Taysha: TSHA-102 Presses On With IND Part B Protocol And SAP Amendments

May 29

Recent updates

Taysha: TSHA-102 Presses On With IND Part B Protocol And SAP Amendments

May 29
User avatar

FDA Meetings And TSHA-102 Trials Will Advance Approval

Advancements in TSHA-102 trials and regulatory discussions could expedite approval and boost future revenue and investor confidence.

Taysha Gene Therapies Is Showing Promise For Rett Syndrome

Jan 28

Taysha Gene Therapies: Unjustified Sell-Off - Enough Cash Runway And Promising Rett Syndrome Data

Oct 14

More Unpleasant Surprises Could Be In Store For Taysha Gene Therapies, Inc.'s (NASDAQ:TSHA) Shares After Tumbling 37%

Jun 27
More Unpleasant Surprises Could Be In Store For Taysha Gene Therapies, Inc.'s (NASDAQ:TSHA) Shares After Tumbling 37%

Taysha Gene Therapies: Latest Rett Data Checks Momentum, Road Ahead Rocky

Jun 20

Growth Investors: Industry Analysts Just Upgraded Their Taysha Gene Therapies, Inc. (NASDAQ:TSHA) Revenue Forecasts By 23%

Apr 20
Growth Investors: Industry Analysts Just Upgraded Their Taysha Gene Therapies, Inc. (NASDAQ:TSHA) Revenue Forecasts By 23%

What Taysha Gene Therapies, Inc.'s (NASDAQ:TSHA) 55% Share Price Gain Is Not Telling You

Mar 21
What Taysha Gene Therapies, Inc.'s (NASDAQ:TSHA) 55% Share Price Gain Is Not Telling You

Taysha: Initial Rett Syndrome Data Leads To Other 2024 Catalysts

Mar 20

Taysha: Produces Solid Data But Has Abandoned Programs

Feb 06

Shareholder Returns

TSHAUS BiotechsUS Market
7D2.0%-0.2%0.5%
1Y36.4%-7.9%15.7%

Return vs Industry: TSHA exceeded the US Biotechs industry which returned -7.3% over the past year.

Return vs Market: TSHA exceeded the US Market which returned 15.1% over the past year.

Price Volatility

Is TSHA's price volatile compared to industry and market?
TSHA volatility
TSHA Average Weekly Movement7.6%
Biotechs Industry Average Movement10.8%
Market Average Movement6.5%
10% most volatile stocks in US Market17.4%
10% least volatile stocks in US Market3.0%

Stable Share Price: TSHA has not had significant price volatility in the past 3 months compared to the US market.

Volatility Over Time: TSHA's weekly volatility has decreased from 14% to 8% over the past year.

About the Company

FoundedEmployeesCEOWebsite
201973Sean Nolanwww.tayshagtx.com

Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of monogenic diseases of the central nervous system. It primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; TSHA-114 for the treatment of fragile X syndrome; and TSHA-101 for the treatment of GM2 gangliosidosis. The company has research, collaboration, and license agreement with The University of Texas Southwestern Medical Center.

Taysha Gene Therapies, Inc. Fundamentals Summary

How do Taysha Gene Therapies's earnings and revenue compare to its market cap?
TSHA fundamental statistics
Market capUS$782.92m
Earnings (TTM)-US$92.72m
Revenue (TTM)US$8.10m
101.1x
P/S Ratio
-8.8x
P/E Ratio

Earnings & Revenue

Key profitability statistics from the latest earnings report (TTM)
TSHA income statement (TTM)
RevenueUS$8.10m
Cost of RevenueUS$0
Gross ProfitUS$8.10m
Other ExpensesUS$100.82m
Earnings-US$92.72m

Last Reported Earnings

Jun 30, 2025

Next Earnings Date

n/a

Earnings per share (EPS)-0.34
Gross Margin100.00%
Net Profit Margin-1,144.97%
Debt/Equity Ratio16.5%

How did TSHA perform over the long term?

See historical performance and comparison

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2025/08/22 19:25
End of Day Share Price 2025/08/22 00:00
Earnings2025/06/30
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Taysha Gene Therapies, Inc. is covered by 23 analysts. 12 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Jack AllenBaird
Keith TapperBMO Capital Markets Equity Research
Evan SeigermanBMO Capital Markets Equity Research