Taysha Gene Therapies, Inc.

NasdaqGS:TSHA Stock Report

Market Cap: US$1.3b

Taysha Gene Therapies Ownership

Who are the major shareholders and have insiders been buying or selling?

Recent Insider Transactions

NasdaqGS:TSHA Recent Insider Transactions by Companies or Individuals
DateValueNameEntityRoleSharesMax Price
21 Aug 25SellUS$155,299Kamran AlamIndividual54,491US$2.85
21 Aug 25SellUS$162,604Sukumar NagendranIndividual57,054US$2.85
30 May 25BuyUS$2,062,500Paul ManningIndividual750,000US$2.75

Insider Trading Volume

Insider Buying: TSHA insiders have only sold shares in the past 3 months.

Ownership Breakdown

What is the ownership structure of TSHA?
Owner TypeNumber of SharesOwnership Percentage
Private Companies45,0000.0156%
VC/PE Firms23,555,6488.15%
Individual Insiders29,046,77210%
Hedge Funds46,721,58416.2%
Institutions189,663,32565.6%

Dilution of Shares: Shareholders have been substantially diluted in the past year, with total shares outstanding growing by 33.1%.

Top Shareholders

Top 25 shareholders own 93.66% of the company
OwnershipNameSharesCurrent ValueChange %Portfolio %
9.38%
Paul Manning
25,579,111US$124.8m3.02%no data
9.17%
RTW Investments, LP
25,021,584US$122.1m33.2%1.35%
8.63%
RA Capital Management, L.P.
23,555,648US$115.0m117%1.27%
7.95%
Avoro Capital Advisors LLC
21,700,000US$105.9m8.5%1.32%
6.18%
Morgan Stanley
16,858,644US$82.3m0.17%0.01%
5.73%
FMR LLC
15,627,562US$76.3m-0.03%no data
4.88%
BlackRock, Inc.
13,303,775US$64.9m-2.1%no data
4.62%
Octagon Capital Advisors LP
12,592,500US$61.5m17.7%8.05%
4.59%
The Goldman Sachs Group, Inc.
12,527,045US$61.1m3,880%0.02%
4.04%
Artal Group S.A.
11,014,737US$53.8m69.1%1.32%
3.99%
The Vanguard Group, Inc.
10,894,127US$53.2m24.2%no data
3.78%
Jefferies Financial Group Inc.
10,313,733US$50.3m4,110%0.7%
2.69%
Point72 Asset Management, L.P.
7,347,307US$35.9m60.2%0.06%
1.97%
Deerfield Management Company, L.P.
5,386,000US$26.3m0%0.42%
1.88%
State Street Global Advisors, Inc.
5,138,310US$25.1m58.9%no data
1.83%
Polar Capital Holdings Plc
5,000,000US$24.4m66.7%0.07%
1.77%
Adage Capital Management, L.P.
4,839,000US$23.6m0%0.04%
1.73%
Cowen Inc.
4,728,806US$23.1m0%2.04%
1.5%
Tybourne Capital Management (HK) Ltd.
4,095,000US$20.0m10.7%40.63%
1.47%
Baker Bros. Advisors LP
4,004,756US$19.5m0%0.13%
1.39%
Geode Capital Management, LLC
3,793,572US$18.5m3.52%no data
1.18%
Suvretta Capital Management, LLC
3,217,449US$15.7m0%0.48%
1.1%
ADAR1 Capital Management, LLC
3,009,870US$14.7m182%1.48%
1.1%
Vestal Point Capital, LP
3,000,000US$14.6m0%0.57%
1.08%
MPM BioImpact LLC
2,953,562US$14.4m0%1.97%

Company Analysis and Financial Data Status

DataLast Updated (UTC time)
Company Analysis2025/10/03 17:30
End of Day Share Price 2025/10/03 00:00
Earnings2025/06/30
Annual Earnings2024/12/31

Data Sources

The data used in our company analysis is from S&P Global Market Intelligence LLC. The following data is used in our analysis model to generate this report. Data is normalised which can introduce a delay from the source being available.

PackageDataTimeframeExample US Source *
Company Financials10 years
  • Income statement
  • Cash flow statement
  • Balance sheet
Analyst Consensus Estimates+3 years
  • Forecast financials
  • Analyst price targets
Market Prices30 years
  • Stock prices
  • Dividends, Splits and Actions
Ownership10 years
  • Top shareholders
  • Insider trading
Management10 years
  • Leadership team
  • Board of directors
Key Developments10 years
  • Company announcements

* Example for US securities, for non-US equivalent regulatory forms and sources are used.

Unless specified all financial data is based on a yearly period but updated quarterly. This is known as Trailing Twelve Month (TTM) or Last Twelve Month (LTM) Data. Learn more.

Analysis Model and Snowflake

Details of the analysis model used to generate this report is available on our Github page, we also have guides on how to use our reports and tutorials on Youtube.

Learn about the world class team who designed and built the Simply Wall St analysis model.

Industry and Sector Metrics

Our industry and section metrics are calculated every 6 hours by Simply Wall St, details of our process are available on Github.

Analyst Sources

Taysha Gene Therapies, Inc. is covered by 23 analysts. 12 of those analysts submitted the estimates of revenue or earnings used as inputs to our report. Analysts submissions are updated throughout the day.

AnalystInstitution
Jack AllenBaird
Keith TapperBMO Capital Markets Equity Research
Evan SeigermanBMO Capital Markets Equity Research