Spyre Therapeutics Gelecekteki Büyüme

Future kriter kontrolleri 0/6

Spyre Therapeutics'in kazancının yıllık 17% oranında azalması, yıllık gelirinin ise yıllık 77.5% oranında artması beklenmektedir. EPS'nin düşmesi beklenmektedir. Özkaynak kârlılığının 3 yıl içinde -58.9% olacağı tahmin edilmektedir.

Anahtar bilgiler

-17.0%

Kazanç büyüme oranı

-10.92%

EPS büyüme oranı

Biotechs kazanç büyümesi	25.3%
Gelir büyüme oranı	77.5%
Gelecekteki özkaynak getirisi	-58.91%
Analist kapsamı	Good
Son güncelleme	20 May 2026

Gelecekteki son büyüme güncellemeleri

Recent updates

Seeking Alpha • Mar 17

Spyre: 'Strong Buy' As UC Program Moves Along And Q3 2026 RA Data Looms

Summary Spyre Therapeutics, Inc. receives a Strong Buy rating, driven by positive phase 1 data and robust pipeline progress in IBD and rheumatic diseases. SPY001 demonstrated a half-life 4x greater than ENTYVIO, supporting quarterly or twice-yearly dosing for ulcerative colitis in the ongoing phase 2 SKYLINE trial. Accelerated recruitment in the phase 2 SKYWAY RA sub-study brings the anti-TL1A SPY072 data readout forward to Q3 2026, enhancing SYRE's near-term catalysts. SYRE's $757M cash position funds operations into H2 2028, supporting multiple clinical milestones and reducing near-term financing risk. Read the full article on Seeking Alpha

Analiz Makalesi • Jul 15

Companies Like Spyre Therapeutics (NASDAQ:SYRE) Are In A Position To Invest In Growth

We can readily understand why investors are attracted to unprofitable companies. For example, although...

Seeking Alpha • Mar 04

Spyre Therapeutics: Targeting The Future Of IBD Treatment

Summary Spyre Therapeutics is emerging as a key player in inflammatory bowel disease, with a focus on pathway-specific monoclonal antibodies for superior disease control. The company has a healthy balance sheet with $603.1 million in cash, providing a four-year runway at its current burn rate. SYRE's innovative combination therapy approach targets multiple inflammatory pathways, aiming for better efficacy and long-term disease control in ulcerative colitis. Upcoming clinical trials in 2025 and 2026 are critical for validating Spyre's therapies and determining its potential to shift the treatment paradigm. Read the full article on Seeking Alpha

Seeking Alpha • Dec 12

Spyre Therapeutics: Different Name, Same Tune

Summary Today, we take an in-depth look at Spyre Therapeutics, Inc., which has promising assets in early-stage development, including SPY001, SPY002, and SPY003. The company changed its name from Aeglea BioTherapeutics, Inc. late last year, and thanks to a recent capital raise, is extremely well funded. Analyst firms also appear optimistic around the company's developmental approach. An analysis of SYRE stock follows in the paragraphs below. Read the full article on Seeking Alpha

Seeking Alpha • Oct 01

Spyre: Extended Half-Life Tech To Become Differentiating Factor For IBD Targeting

Summary Spyre Therapeutics, Inc. interim data from the phase 1 study, using SPY001 in healthy volunteers, is expected by the end of 2024. SPY001 is an a4b7 inhibitor being developed to target IBD like Crohn's Disease and Ulcerative Colitis. The Crohn's Disease treatment market is projected to reach a value of $17.80 billion by 2033. The global Ulcerative Colitis market is expected to be $10.79 billion by 2030. Read the full article on Seeking Alpha

Seeking Alpha • Aug 18

Aeglea stock jumps ~58% after hours on European nod for enzyme pegzilarginase

Aeglea BioTherapeutics (NASDAQ:AGLE) on Thursday said Europe's drug regulator had validated the company's marketing authorization application for enzyme pegzilarginase for the treatment of Arginase 1 deficiency. Shares of the micro-cap clinical-stage biotech soared 57.5% to $0.80 in postmarket trading. The application was submitted by AGLE's commercialization partner in Europe and Middle East, Immedica Pharma, AGLE said in a statement. Arginase 1 deficiency is a rare, inherited disorder in which there is complete or partial lack of the enzyme arginase in the liver and red blood cells. Aeglea (AGLE) earlier in Aug. reported a mixed set of Q2 results.

Seeking Alpha • Aug 04

Aeglea BioTherapeutics GAAP EPS of -$0.27 beats by $0.04, revenue of $0.63M misses by $0.08M

Aeglea BioTherapeutics press release (NASDAQ:AGLE): Q2 GAAP EPS of -$0.27 (vs. -0.10 Y/Y) beats by $0.04. Revenue of $0.63M (-95.4% Y/Y) misses by $0.08M. Shares +5.07% PM.

Seeking Alpha • Dec 07

Aeglea Presents Itself As Buy Opportunity After Latest Data Causes Stock To Trade Lower

Aeglea achieved primary endpoint in reducing arginine levels with its drug pegzilarginase for ARG1-D, which in turn reduced ammonia in the blood plasma, by an average of 80%. BLA filing of pegzilarginase for patients with ARG1-D is expected to occur in 1st half of 2022. Additional results from the phase 3 PEACE study, using pegzilarginase for patients with ARG1-D, are expected to be released at an upcoming medical meeting and in peer-reviewed medical journals. The company will also submit a regulatory application for pegzilarginase for ARG1-D, with its partner Immedica Pharma, to Europe and other Middle East countries in 2022.

Kazanç ve Gelir Büyüme Tahminleri

NasdaqGS:SYRE - Analistlerin gelecek tahminleri ve geçmiş finansal verileri (USD Millions )
Tarih	Gelir	Kazançlar	Serbest Nakit Akışı	Faaliyetlerden Nakit	Avg. Analist Sayısı
12/31/2028	N/A	-334	-299	-285	9
12/31/2027	N/A	-297	-275	-247	12
12/31/2026	N/A	-260	-185	-164	12
3/31/2026	N/A	-149	-149	-186	N/A
12/31/2025	N/A	-127	-162	-169	N/A
9/30/2025	N/A	-118	-162	-162	N/A
6/30/2025	N/A	-162	-154	-154	N/A
3/31/2025	N/A	-159	-170	-170	N/A
12/31/2024	N/A	-150	-157	-157	N/A
9/30/2024	N/A	75	-151	-151	N/A
6/30/2024	N/A	88	-141	-156	N/A
3/31/2024	1	-103	-96	-111	N/A
12/31/2023	1	-95	-85	-100	N/A
9/30/2023	1	-294	-72	-87	N/A
6/30/2023	1	-273	-67	-67	N/A
3/31/2023	1	-78	-72	-72	N/A
12/31/2022	2	-84	-80	-80	N/A
9/30/2022	6	-85	-81	-81	N/A
6/30/2022	7	-88	-83	-83	N/A
3/31/2022	20	-72	-61	-60	N/A
12/31/2021	19	-66	-54	-54	N/A
9/30/2021	15	-68	-53	-52	N/A
6/30/2021	14	-66	-54	-52	N/A
3/31/2021	N/A	-80	-77	-74	N/A
12/31/2020	N/A	-81	-80	-76	N/A
9/30/2020	N/A	-80	-79	-75	N/A
6/30/2020	N/A	-83	-79	-75	N/A
3/31/2020	N/A	-80	-74	-72	N/A
12/31/2019	N/A	-78	N/A	-66	N/A
9/30/2019	N/A	-72	N/A	-57	N/A
6/30/2019	N/A	-62	N/A	-48	N/A
3/31/2019	2	-53	N/A	-41	N/A
12/31/2018	4	-44	N/A	-32	N/A
9/30/2018	5	-36	N/A	-31	N/A
6/30/2018	7	-32	N/A	-30	N/A
3/31/2018	6	-29	N/A	-27	N/A
12/31/2017	5	-27	N/A	-25	N/A
9/30/2017	5	-26	N/A	-23	N/A
6/30/2017	5	-25	N/A	-22	N/A
3/31/2017	5	-23	N/A	-20	N/A
12/31/2016	5	-22	N/A	-19	N/A
9/30/2016	5	-20	N/A	-15	N/A
6/30/2016	5	-17	N/A	-13	N/A
3/31/2016	7	-13	N/A	-12	N/A
12/31/2015	6	-12	N/A	-11	N/A
9/30/2015	5	-11	N/A	-13	N/A
6/30/2015	3	-11	N/A	-11	N/A

Analist Gelecek Büyüme Tahminleri

Kazançlar ve Tasarruf Oranları: SYRE önümüzdeki 3 yıl boyunca kârsız kalmaya devam edeceği tahmin ediliyor.

Kazançlar ve Piyasa: SYRE önümüzdeki 3 yıl boyunca kârsız kalmaya devam edeceği tahmin ediliyor.

Yüksek Büyüme Kazançları: SYRE önümüzdeki 3 yıl boyunca kârsız kalmaya devam edeceği tahmin ediliyor.

Gelir ve Pazar: SYRE gelecek yıl gelir elde edemeyeceği tahmin ediliyor.

Yüksek Büyüme Geliri: SYRE gelecek yıl gelir elde edemeyeceği tahmin ediliyor.

Hisse Başına Kazanç Büyüme Tahminleri

Gelecekteki Özkaynak Getirisi

Gelecekteki ROE: SYRE 3 yıl içinde kârsız olması bekleniyor.

Büyüyen şirketleri keşfedin

Şirket Analizi ve Finansal Veri Durumu

Veri	Son Güncelleme (UTC saati)
Şirket Analizi	2026/05/22 07:37
Gün Sonu Hisse Fiyatı	2026/05/22 00:00
Kazançlar	2026/03/31
Yıllık Kazançlar	2025/12/31

Veri Kaynakları

Şirket analizimizde kullanılan veriler S&P Global Market Intelligence LLC'den alınmıştır. Bu raporu oluşturmak için analiz modelimizde aşağıdaki veriler kullanılmıştır. Veriler normalize edilmiştir, bu da kaynağın mevcut olmasından kaynaklanan bir gecikmeye neden olabilir.

Paket	Veri	Zaman Çerçevesi	Örnek ABD Kaynağı ^*
Şirket Finansalları	10 yıl	Gelir tablosu Nakit akış tablosu Bilanço	SEC Form 10-K SEC Form 10-Q
Analist Konsensüs Tahminleri	+3 yıl	Finansal tahminler Analist fiyat hedefleri	Analist Araştırma Raporları Blue Matrix
Piyasa Fiyatları	30 yıl	Hisse senedi fiyatları Temettüler, Bölünmeler ve Eylemler	ICE Piyasa Verileri SEC Form S-1
Sahiplik	10 yıl	En büyük hissedarlar İçeriden öğrenenlerin ticareti	SEC Form 4 SEC Form 13D
Yönetim	10 yıl	Liderlik ekibi Yönetim Kurulu	SEC Form 10-K SEC Form DEF 14A
Önemli Gelişmeler	10 yıl	Şirket duyuruları	SEC Form 8-K

* ABD menkul kıymetleri için örnek, ABD dışı için eşdeğer düzenleyici formlar ve kaynaklar kullanılmıştır.

Belirtilmediği sürece tüm finansal veriler yıllık bir döneme dayanmaktadır ancak üç ayda bir güncellenmektedir. Bu, İzleyen On İki Ay (TTM) veya Son On İki Ay (LTM) Verileri olarak bilinir. Daha fazla bilgi edinin.

Analiz Modeli ve Kar Tanesi

Bu raporu oluşturmak için kullanılan analiz modelinin ayrıntılarına GitHub sayfamızdan ulaşabilirsiniz, ayrıca raporlarımızı nasıl kullanacağınızı anlatan kılavuzlarımız ve Youtube'da eğitim videolarımız da bulunmaktadır.

Simply Wall St analiz modelini tasarlayan ve oluşturan dünya standartlarındaki ekip hakkında bilgi edinin.

Endüstri ve Sektör Metrikleri

Sektör ve bölüm metriklerimiz Simply Wall St tarafından her 6 saatte bir hesaplanmaktadır, sürecimizin ayrıntıları Github'da mevcuttur.

Analist Kaynakları

Spyre Therapeutics, Inc. 24 Bu analistlerden 12, raporumuzun girdisi olarak kullanılan gelir veya kazanç tahminlerini sunmuştur. Analistlerin gönderimleri gün boyunca güncellenmektedir.

Analist	Kurum
Colleen Kusy	Baird
Mayur Somaiya	BMO Capital Markets Equity Research
Julian Harrison	BTIG

Spyre Therapeutics Gelecekteki Büyüme

Future kriter kontrolleri 0/6

Anahtar bilgiler

Gelecekteki son büyüme güncellemeleri

Price target increased by 11% to US$67.43

Price target increased by 9.9% to US$64.36

Consensus revenue estimates increase by 48%

Price target increased by 20% to US$3.12

Consensus EPS estimates upgraded to US$0.61 loss

Price target decreased by 16% to US$2.27

Recent updates

Spyre Therapeutics Advances Six Mid-Stage Trials With Accelerated Data Readouts in 2026

New minor risk - Share price stability

Spyre Therapeutics, Inc. has completed a Follow-on Equity Offering in the amount of $403 million.

Spyre Therapeutics, Inc. has filed a Follow-on Equity Offering in the amount of $300 million.

Price target increased by 11% to US$67.43

Spyre Therapeutics, Inc., Annual General Meeting, May 27, 2026

Price target increased by 9.9% to US$64.36

Spyre: 'Strong Buy' As UC Program Moves Along And Q3 2026 RA Data Looms

Spyre Therapeutics, Inc. Announces Acceleration of Expected Topline Readout of SKYWAY Rheumatoid Arthritis Sub-study to Third Quarter 2026

CEO & Director notifies of intention to sell stock

Spyre Therapeutics, Inc. Appoints Kate Tansey Chevlen as Chief Commercial Officer

New minor risk - Share price stability

Spyre Therapeutics Announces Positive Interim Phase 1 Results for SPY003, Its Novel, Half-Life Extended Anti-IL-23 Antibody

CEO & Director notifies of intention to sell stock

New major risk - Shareholder dilution

New minor risk - Share price stability

Spyre Therapeutics, Inc. has completed a Follow-on Equity Offering in the amount of $275.000003 million.

Spyre Therapeutics, Inc. Doses First Patient in Pioneering Phase 2 SKYway Basket Trial of SPY072, the First Anti-TL1A Antibody Studied in Rheumatic Diseases

Chief Financial Officer recently sold US$300k worth of stock

Companies Like Spyre Therapeutics (NASDAQ:SYRE) Are In A Position To Invest In Growth

High number of new and inexperienced directors

Spyre Therapeutics, Inc. Announces Positive Interim Phase 1 Results for Two Next-Generation TL1A Antibody Programs, and Provides Clinical Development Updates Expected to Deliver 9 Phase 2 Readouts

Spyre Therapeutics, Inc. Announces Poster Presentations at Digestive Disease Week 2025 Including Up to Eight Months of Follow-Up from an Ongoing Phase 1 Trial of SPY001

Spyre Therapeutics, Inc., Annual General Meeting, May 29, 2025

Spyre Therapeutics Announces First Participant Dosed in Phase 1 Trial of Spy003, Its Novel Half-Life Extended Il-23 Antibody

Spyre Therapeutics: Targeting The Future Of IBD Treatment

Spyre Therapeutics: Different Name, Same Tune

Spyre Therapeutics Announces First Participants Dosed in Phase 1 Trials of Novel Half-Life Extended Anti-Tl1a Antibodies

Spyre Therapeutics, Inc. has completed a Follow-on Equity Offering.

Spyre Therapeutics, Inc. has filed a Follow-on Equity Offering in the amount of $200 million.

Spyre Therapeutics, Inc. Announces Positive Interim Phase 1 Data from its First-In-Human Trial of SPY001

Spyre: Extended Half-Life Tech To Become Differentiating Factor For IBD Targeting

Spyre Therapeutics Appoints Dr. Sheldon Sloan as Chief Medical Officer

Spyre Therapeutics, Inc. Announces First Participants Dose in Phase 1 Trial of SPY001

Spyre Therapeutics, Inc. Announces Board Changes

Spyre Therapeutics, Inc., Annual General Meeting, May 13, 2024

Spyre Therapeutics, Inc. announced that it expects to receive $180.005 million in funding from a group of investors

Spyre Therapeutics, Inc. Announces Board Changes

Spyre Therapeutics, Inc. announced that it has received $180 million in funding from a group of investors

Spyre Therapeutics, Inc. announced that it expects to receive $180 million in funding from a group of investors

Spyre Therapeutics, Inc.(NasdaqCM:SYRE) dropped from NASDAQ Composite Index

Aeglea BioTherapeutics, Inc. Announces Appointment of Cameron Turtle as Principal Executive Officer

Aeglea Biotherapeutics, Inc. Regains Compliance with Nasdaq Listing Rule

Aeglea Biotherapeutics Expands Executive Leadership Team with Appointment of Industry Veterans Scott Burrows and Heidy Abreu King-Jones

Immedica Pharma signed an agreement to acquire global rights to pegzilarginase from Aeglea BioTherapeutics, Inc from Aeglea BioTherapeutics, Inc. (NasdaqCM:AGLE) for $115 million.

Aeglea Biotherapeutics Receives Approval from Nasdaq of the Transfer of the Listing of Its Common Stock from Nasdaq Global Market to the Nasdaq Capital Market

High number of new directors

Aeglea BioTherapeutics, Inc. announced that it expects to receive $210.000248 million in funding from a group of investors

New major risk - Share price stability

Aeglea Biotherapeutics, Inc. Announces the Termination of Jeffrey Goldberg as Chief Executive Officer

Aeglea BioTherapeutics, Inc. Announces Executive Changes

Consensus revenue estimates increase by 48%

Price target increased by 20% to US$3.12

Consensus EPS estimates upgraded to US$0.61 loss

Price target decreased by 16% to US$2.27

No longer forecast to breakeven

Aeglea BioTherapeutics Receives Written Notice from The Nasdaq Stock Market, LLC Regarding Minimum Bid Price Requirement for Continued Listing

Aeglea Biotherapeutics, Inc. Announces Resignation of Leslie Sloan as Chief Operating Officer

Aeglea Biotherapeutics, Inc. Announces Chief Executive Officer Changes

Aeglea BioTherapeutics, Inc. Appoints Linda Neuman as Chief Medical Officer

Price target increased to US$2.70

Consensus forecasts updated

Price target increased to US$2.70

Aeglea BioTherapeutics, Inc. Provides Clinical Progress and Regulatory Update for Homocystinuria Program

Insider recently bought US$50k worth of stock

Aeglea Biotherapeutics Announces Leadership Transition

Aeglea BioTherapeutics, Inc. Announces European Medicines Agency Validation of Marketing Authorization Application for Pegzilarginase for the Treatment of Arginase 1 Deficiency

Aeglea stock jumps ~58% after hours on European nod for enzyme pegzilarginase

Consensus forecasts updated